EA201370063A1 - Фосфолипидом рака - Google Patents
Фосфолипидом ракаInfo
- Publication number
- EA201370063A1 EA201370063A1 EA201370063A EA201370063A EA201370063A1 EA 201370063 A1 EA201370063 A1 EA 201370063A1 EA 201370063 A EA201370063 A EA 201370063A EA 201370063 A EA201370063 A EA 201370063A EA 201370063 A1 EA201370063 A1 EA 201370063A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- cancer
- diagnosing
- derived
- analysis
- phospholypide
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
- G01N2333/918—Carboxylic ester hydrolases (3.1.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Physiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
В целом, изобретение относится к идентификации липидомных биомаркеров для анализа на рак и обеспечивает прогностические и предиктивные способы и наборы для диагностики и субтипирования рака и для диагностики и/или прогнозирования развития опухоли и ее ответа на нацеленную на липидный метаболизм или другие типы терапии у субъекта путем применения анализа фосфолипидного профиля, при котором признаками фенотипа удлинения служат изменения объединенной длины ацильных цепей интактных видов фосфолипидов, полученных из биологических жидкостей или полученных из опухоли.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1016139.6A GB201016139D0 (en) | 2010-09-24 | 2010-09-24 | Cancer phosholipidome |
PCT/EP2011/051936 WO2011098509A1 (en) | 2010-02-11 | 2011-02-10 | Phospholipid profiling and cancer |
PCT/EP2011/066568 WO2012038525A1 (en) | 2010-09-24 | 2011-09-23 | Cancer phospholipidome |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201370063A1 true EA201370063A1 (ru) | 2013-08-30 |
Family
ID=43127956
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201370063A EA201370063A1 (ru) | 2010-09-24 | 2011-09-23 | Фосфолипидом рака |
Country Status (6)
Country | Link |
---|---|
US (1) | US9400274B2 (ru) |
CN (1) | CN103119447A (ru) |
BR (1) | BR112013006528A2 (ru) |
EA (1) | EA201370063A1 (ru) |
GB (1) | GB201016139D0 (ru) |
WO (1) | WO2012038525A1 (ru) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9164084B2 (en) | 2012-01-31 | 2015-10-20 | Purdue Research Foundation | Methods for determining aggressiveness of a cancer and treatment thereof |
WO2015085225A1 (en) * | 2013-12-06 | 2015-06-11 | Hector De Leon | Lipid biomarker signatures for lung injury diagnosis |
WO2016051020A1 (en) | 2014-10-02 | 2016-04-07 | Zora Biosciences Oy | Methods for detecting ovarian cancer |
EP3307243A4 (en) * | 2015-06-09 | 2019-01-02 | The Board of Regents of The University of Texas System | Diagnostic test for early stage cancer |
CN106802334A (zh) * | 2015-11-26 | 2017-06-06 | 中国医学科学院基础医学研究所 | 一组监测癌症疾病进展和或耐药性产生的个体化标志物 |
EP3427066A4 (en) * | 2016-03-10 | 2020-02-19 | Agency for Science, Technology and Research | LIPID BIOMARKERS FOR CANCER DIAGNOSIS |
CN106526028A (zh) * | 2016-11-14 | 2017-03-22 | 中国药科大学 | 代谢标志物在诊断鉴别甲状腺良恶性病变中的应用 |
CN106770873B (zh) * | 2017-01-19 | 2019-02-19 | 中国人民解放军第四军医大学 | 一种膀胱癌诊断标志物及其应用和诊断试剂盒 |
US20180246112A1 (en) * | 2017-02-28 | 2018-08-30 | University Of Kentucky Research Foundation | Biomarkers of Breast and Lung Cancer |
CN108872578B (zh) * | 2017-05-11 | 2021-07-02 | 首都医科大学附属北京口腔医院 | 一种诊断和监测口腔癌的新方法 |
EP3649472A1 (en) | 2017-07-05 | 2020-05-13 | Zora Biosciences OY | Methods for detecting ovarian cancer |
CN109212216B (zh) * | 2018-10-31 | 2019-07-09 | 中国药科大学 | 对羟基肉桂酸或磷脂酰乙醇胺在大肠癌早期诊断方面的应用 |
WO2020163581A1 (en) * | 2019-02-06 | 2020-08-13 | Berg Llc | Markers for the diagnosis of biochemical recurrence in prostate cancer |
KR102156217B1 (ko) * | 2019-03-05 | 2020-09-15 | 연세대학교 산학협력단 | 대장암 진단용 지질 바이오마커 및 이의 용도 |
WO2020182995A1 (en) * | 2019-03-14 | 2020-09-17 | Universität Heidelberg | Vlcfa-containing lipids as prognostic and predictive marker for cancer therapies |
AU2020287121A1 (en) * | 2019-06-04 | 2022-01-06 | Avanti Polar Lipids, Llc | Universal lipid quantitative standards for use in lipidomics |
CN116027041B (zh) * | 2023-01-13 | 2023-12-05 | 郑州大学第一附属医院 | 口腔癌辅助诊断标志物、试剂盒及其应用 |
CN117388495B (zh) * | 2023-12-13 | 2024-02-09 | 哈尔滨脉图精准技术有限公司 | 用于诊断肺癌分期的代谢标志物的应用及试剂盒 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20010005550A (ko) * | 1997-03-21 | 2001-01-15 | 아타르진 테크놀로지스 인코퍼레이티드 | 리소포스포리피드 농도 변화와 연관된 암 감지 방법 |
US6248553B1 (en) * | 1998-10-22 | 2001-06-19 | Atairgin Technologies, Inc. | Enzyme method for detecting lysophospholipids and phospholipids and for detecting and correlating conditions associated with altered levels of lysophospholipids |
IL158552A0 (en) * | 2003-10-22 | 2004-05-12 | Enzymotec Ltd | Lipids containing omega-3 fatty acids |
US8067153B2 (en) * | 2005-07-27 | 2011-11-29 | Oncotheraphy Science, Inc. | Genes and polypeptides relating to prostate cancers |
EP2002262B1 (en) * | 2006-03-15 | 2016-06-22 | The General Hospital Corporation | Devices and methods for detecting cells and other analytes |
JP5778185B2 (ja) | 2010-02-11 | 2015-09-16 | カトリーケ・ウニベルシタイト・リユーベン | リン脂質プロファイリング及びガン |
-
2010
- 2010-09-24 GB GBGB1016139.6A patent/GB201016139D0/en not_active Ceased
-
2011
- 2011-09-23 CN CN2011800455995A patent/CN103119447A/zh active Pending
- 2011-09-23 EA EA201370063A patent/EA201370063A1/ru unknown
- 2011-09-23 BR BR112013006528A patent/BR112013006528A2/pt not_active IP Right Cessation
- 2011-09-23 WO PCT/EP2011/066568 patent/WO2012038525A1/en active Application Filing
-
2013
- 2013-03-25 US US13/849,885 patent/US9400274B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2012038525A1 (en) | 2012-03-29 |
US20140220613A1 (en) | 2014-08-07 |
GB201016139D0 (en) | 2010-11-10 |
CN103119447A (zh) | 2013-05-22 |
US9400274B2 (en) | 2016-07-26 |
BR112013006528A2 (pt) | 2016-08-02 |
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