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EA201170616A1 - Лекарственная форма ацетаминофен/трамадол с замедленным действием для перорального приема - Google Patents

Лекарственная форма ацетаминофен/трамадол с замедленным действием для перорального приема

Info

Publication number
EA201170616A1
EA201170616A1 EA201170616A EA201170616A EA201170616A1 EA 201170616 A1 EA201170616 A1 EA 201170616A1 EA 201170616 A EA201170616 A EA 201170616A EA 201170616 A EA201170616 A EA 201170616A EA 201170616 A1 EA201170616 A1 EA 201170616A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tramadol
dosage form
acetaminophen
action
slowed
Prior art date
Application number
EA201170616A
Other languages
English (en)
Other versions
EA023149B1 (ru
Inventor
Вэй-го Дай
Лян-чан Дун
Тае-хонг Чой
Сунг Дзоо Хванг
Дзае Хиун Ким
Донг Хо Ли
Original Assignee
Алза Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41514164&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201170616(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Алза Корпорейшн filed Critical Алза Корпорейшн
Publication of EA201170616A1 publication Critical patent/EA201170616A1/ru
Publication of EA023149B1 publication Critical patent/EA023149B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Лекарственная форма, содержащая ацетаминофен и трамадол, с замедленным действием для перорального приема. Лекарственная форма включает композицию ацетаминофена и комплекса трамадола с анионным полимером. Комплекс трамадола обеспечивает замедленное высвобождение трамадола для синхронизированного (согласованного) характера высвобождения ацетаминофена и трамадола.
EA201170616A 2008-10-27 2009-10-23 Фармацевтическая композиция, содержащая ацетаминофен и комплекс трамадола с каррагинаном, лекарственная форма, способ ее изготовления и применение комплекса трамадола с каррагинаном для лечения боли EA023149B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10861808P 2008-10-27 2008-10-27
PCT/US2009/061803 WO2010062524A1 (en) 2008-10-27 2009-10-23 Extended release oral acetaminophen/tramadol dosage form

Publications (2)

Publication Number Publication Date
EA201170616A1 true EA201170616A1 (ru) 2011-12-30
EA023149B1 EA023149B1 (ru) 2016-04-29

Family

ID=41514164

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201170616A EA023149B1 (ru) 2008-10-27 2009-10-23 Фармацевтическая композиция, содержащая ацетаминофен и комплекс трамадола с каррагинаном, лекарственная форма, способ ее изготовления и применение комплекса трамадола с каррагинаном для лечения боли

Country Status (26)

Country Link
US (1) US20100104638A1 (ru)
EP (1) EP2362768B1 (ru)
JP (1) JP5713911B2 (ru)
KR (3) KR20110036858A (ru)
CN (2) CN102264355A (ru)
AU (1) AU2009320181B2 (ru)
BR (1) BRPI0920082A2 (ru)
CA (1) CA2741751C (ru)
CL (1) CL2011000935A1 (ru)
CO (1) CO6331423A2 (ru)
CR (1) CR20110287A (ru)
EA (1) EA023149B1 (ru)
EC (1) ECSP11011009A (ru)
ES (1) ES2582779T3 (ru)
HK (1) HK1162915A1 (ru)
HN (1) HN2011001184A (ru)
IL (1) IL212453A (ru)
MX (1) MX339867B (ru)
MY (1) MY161550A (ru)
NI (1) NI201100079A (ru)
NZ (1) NZ592325A (ru)
PE (1) PE20110855A1 (ru)
TW (1) TWI561257B (ru)
UA (1) UA102706C2 (ru)
WO (1) WO2010062524A1 (ru)
ZA (1) ZA201103880B (ru)

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CN105764491A (zh) 2013-12-09 2016-07-13 度瑞公司 药物活性剂复合物、聚合物复合物，以及包括其的组合物和方法
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CA2947786A1 (en) 2014-05-12 2015-11-19 Grunenthal Gmbh Tamper resistant immediate release capsule formulation comprising tapentadol
CA2949422A1 (en) 2014-05-26 2015-12-03 Grunenthal Gmbh Multiparticles safeguarded against ethanolic dose-dumping
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Also Published As

Publication number Publication date
CA2741751A1 (en) 2010-06-03
HK1162915A1 (zh) 2012-09-07
MX2011004403A (es) 2011-05-25
US20100104638A1 (en) 2010-04-29
NZ592325A (en) 2012-09-28
WO2010062524A1 (en) 2010-06-03
CA2741751C (en) 2017-05-09
ES2582779T3 (es) 2016-09-15
JP2012506907A (ja) 2012-03-22
EP2362768A1 (en) 2011-09-07
KR20110036858A (ko) 2011-04-11
AU2009320181B2 (en) 2015-08-27
CN102264355A (zh) 2011-11-30
AU2009320181A1 (en) 2010-06-03
CL2011000935A1 (es) 2011-10-21
JP5713911B2 (ja) 2015-05-07
EA023149B1 (ru) 2016-04-29
EP2362768B1 (en) 2016-04-20
CN107028908A (zh) 2017-08-11
KR20110119845A (ko) 2011-11-02
BRPI0920082A2 (pt) 2019-09-24
MY161550A (en) 2017-04-28
PE20110855A1 (es) 2011-12-05
ECSP11011009A (es) 2011-06-30
KR101631140B1 (ko) 2016-06-20
IL212453A0 (en) 2011-06-30
CR20110287A (es) 2011-11-10
CO6331423A2 (es) 2011-10-20
UA102706C2 (ru) 2013-08-12
HN2011001184A (es) 2014-09-01
IL212453A (en) 2017-03-30
MX339867B (es) 2016-06-14
TW201028180A (en) 2010-08-01
NI201100079A (es) 2011-10-21
TWI561257B (en) 2016-12-11
KR20130137720A (ko) 2013-12-17
ZA201103880B (en) 2012-10-31

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