[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

EA201000928A1 - ТРИАЗОЛО[4,5-d]ПИРИМИДИНОВЫЕ СОЕДИНЕНИЯ ДЛЯ ЛЕЧЕНИЯ АНЕВРИЗМ БРЮШНОЙ АОРТЫ - Google Patents

ТРИАЗОЛО[4,5-d]ПИРИМИДИНОВЫЕ СОЕДИНЕНИЯ ДЛЯ ЛЕЧЕНИЯ АНЕВРИЗМ БРЮШНОЙ АОРТЫ

Info

Publication number
EA201000928A1
EA201000928A1 EA201000928A EA201000928A EA201000928A1 EA 201000928 A1 EA201000928 A1 EA 201000928A1 EA 201000928 A EA201000928 A EA 201000928A EA 201000928 A EA201000928 A EA 201000928A EA 201000928 A1 EA201000928 A1 EA 201000928A1
Authority
EA
Eurasian Patent Office
Prior art keywords
triazolo
treatment
abdominal aortic
pyrimidine compounds
aortic aneurysm
Prior art date
Application number
EA201000928A
Other languages
English (en)
Inventor
Жан-Баптист Мишель
Original Assignee
Астразенека Аб
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Астразенека Аб filed Critical Астразенека Аб
Publication of EA201000928A1 publication Critical patent/EA201000928A1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

В изобретении предложены триазоло[4,5-d]пиримидиновые соединения, действующие в качестве антагонистов рецептора P(P2Y). Соединения полезны для лечения или предупреждения аневризм брюшной аорты.
EA201000928A 2007-12-03 2008-12-02 ТРИАЗОЛО[4,5-d]ПИРИМИДИНОВЫЕ СОЕДИНЕНИЯ ДЛЯ ЛЕЧЕНИЯ АНЕВРИЗМ БРЮШНОЙ АОРТЫ EA201000928A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07301616 2007-12-03
PCT/SE2008/051386 WO2009072967A1 (en) 2007-12-03 2008-12-02 Triazolo [4,5-d] pyrimidine compounds for treatment of abdominal aortic aneurysms

Publications (1)

Publication Number Publication Date
EA201000928A1 true EA201000928A1 (ru) 2010-12-30

Family

ID=40717966

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201000928A EA201000928A1 (ru) 2007-12-03 2008-12-02 ТРИАЗОЛО[4,5-d]ПИРИМИДИНОВЫЕ СОЕДИНЕНИЯ ДЛЯ ЛЕЧЕНИЯ АНЕВРИЗМ БРЮШНОЙ АОРТЫ

Country Status (25)

Country Link
US (2) US20100298350A1 (ru)
EP (1) EP2229172B1 (ru)
JP (1) JP5701060B2 (ru)
KR (1) KR101563757B1 (ru)
CN (2) CN101883565A (ru)
AU (1) AU2008331984B2 (ru)
BR (1) BRPI0819458A2 (ru)
CA (1) CA2707488C (ru)
CY (1) CY1115760T1 (ru)
DK (1) DK2229172T3 (ru)
EA (1) EA201000928A1 (ru)
ES (1) ES2522317T3 (ru)
HK (1) HK1148195A1 (ru)
HR (1) HRP20141081T1 (ru)
IL (1) IL205613A (ru)
MX (1) MX2010006101A (ru)
MY (1) MY159656A (ru)
NZ (1) NZ585513A (ru)
PL (1) PL2229172T3 (ru)
PT (1) PT2229172E (ru)
RS (1) RS53635B1 (ru)
SI (1) SI2229172T1 (ru)
UA (1) UA100864C2 (ru)
WO (1) WO2009072967A1 (ru)
ZA (1) ZA201003599B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102653539B (zh) * 2011-03-01 2014-09-17 秦引林 一种抗血小板聚集化合物及其药物组合
CN102924457A (zh) * 2011-08-12 2013-02-13 上海恒瑞医药有限公司 三唑并嘧啶类衍生物、其制备方法及其用途
US9539246B2 (en) 2011-08-30 2017-01-10 University Of Utah Research Foundation Methods and compositions for treating nephrogenic diabetes insipidus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE217010T1 (de) * 1995-07-11 2002-05-15 Astrazeneca Ab Inhibitoren der plättchenaggregation
AR017014A1 (es) * 1997-07-22 2001-08-22 Astrazeneca Ab Compuestos de triazolo [4,5-d]pirimidina, composiciones farmaceuticas, uso de los mismos para preparar medicamentos y procesos para la preparacionde dichos compuestos
TWI229674B (en) * 1998-12-04 2005-03-21 Astra Pharma Prod Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses
GB0013407D0 (en) * 2000-06-02 2000-07-26 Astrazeneca Ab Forms of a chemical compound
SE0101932D0 (sv) * 2001-05-31 2001-05-31 Astrazeneca Ab Pharmaceutical combinations
WO2009007675A2 (en) * 2007-07-11 2009-01-15 Cardoz Ab Combination for use in the treatment of atherosclerosis comprising a mast cell inhibitor and a p2 gamma 12 antagonist

Also Published As

Publication number Publication date
WO2009072967A1 (en) 2009-06-11
JP2011505417A (ja) 2011-02-24
EP2229172A1 (en) 2010-09-22
UA100864C2 (ru) 2013-02-11
PT2229172E (pt) 2014-11-03
PL2229172T3 (pl) 2015-01-30
HRP20141081T1 (hr) 2015-01-02
CN101883565A (zh) 2010-11-10
MX2010006101A (es) 2010-10-04
KR20100099175A (ko) 2010-09-10
CA2707488A1 (en) 2009-06-11
AU2008331984B2 (en) 2012-08-16
NZ585513A (en) 2012-07-27
ZA201003599B (en) 2012-10-31
AU2008331984A1 (en) 2009-06-11
SI2229172T1 (sl) 2014-12-31
JP5701060B2 (ja) 2015-04-15
US20100298350A1 (en) 2010-11-25
HK1148195A1 (en) 2011-09-02
CN103919781A (zh) 2014-07-16
ES2522317T3 (es) 2014-11-14
KR101563757B1 (ko) 2015-10-27
DK2229172T3 (da) 2014-11-10
US20150272955A1 (en) 2015-10-01
IL205613A0 (en) 2010-11-30
BRPI0819458A2 (pt) 2015-05-05
MY159656A (en) 2017-01-13
RS53635B1 (en) 2015-04-30
EP2229172B1 (en) 2014-09-10
EP2229172A4 (en) 2012-12-26
CA2707488C (en) 2015-07-28
IL205613A (en) 2015-04-30
CY1115760T1 (el) 2017-01-25

Similar Documents

Publication Publication Date Title
ATE530210T1 (de) Endoprothesen
CY1120665T1 (el) Ανθρωποποιημενα αντισωματα anti-cxcr5, παραγωγα αυτων και χρησεις τους
TNSN07323A1 (en) Imidazo (1, 2-a) pyridine compounds as vegf-r2 inhibitors
SG178591A1 (en) Jak2 inhibitors and their use for the treatment of myeloproliferative diseases and cancer
MX2009008347A (es) Oxabicicloheptanos y oxabicicloheptenos, su preparacion y uso.
EA201100133A1 (ru) Антагонисты рецепторов простагландина d
GB2453058A (en) Kinase antagonists
MX2009007075A (es) Metodos de uso para analogos de ciclopamina.
EA200870292A1 (ru) Соединения на основе имидазола, композиции, содержащие их, и способы их применения
MX2009012625A (es) Metodos para el tratamiento, diagnostico y deteccion de trastornos asociados con el fgf21.
WO2007150015A3 (en) Method of treatment
WO2007059257A3 (en) N4-phenyl-quinaz0line-4 -amine derivatives and related compounds as erbb type i receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases
ATE430747T1 (de) 2-pyrimidinyl-pyrazolopyridin-erbb- kinaseinhibitoren
GT200800187A (es) Compuestos de tetrahidropiridotienopirimidina y procedimientos de uso de los mismos
EA200971068A1 (ru) Триазолиламинопиримидиновые соединения
TW200631583A (en) Substituted pteridines for the treatment of inflammatory diseases
TW200800967A (en) Benzimidazole thiophene compounds
PA8842501A1 (es) Compuestos novedosos como ligandos de receptores de canabinoides
DK2041093T3 (da) Til behandling af GPR38-receptor medierede sygdomme anvendelige piperazinylderivativer
WO2008060693A3 (en) Tetracyclic imidazole analogs
EA201000928A1 (ru) ТРИАЗОЛО[4,5-d]ПИРИМИДИНОВЫЕ СОЕДИНЕНИЯ ДЛЯ ЛЕЧЕНИЯ АНЕВРИЗМ БРЮШНОЙ АОРТЫ
TW200740766A (en) Substituted-3-sulfonylindazole derivatives as 5-hydroxytryptamine-6-ligands
CL2008001837A1 (es) Uso de compuestos derivados de cinolin-3-carboxamida en el tratamiento de la esquizofrenia.
EA200971067A1 (ru) Триазолиламинопиримидиновые соединения
DE602005015160D1 (de) Stent-Graft zur Behandlung von Aneurysmen