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EA200301321A1 - Фармацевтические композиции для координированной доставки средств нестероидных противовоспалительных лекарственных средств - Google Patents

Фармацевтические композиции для координированной доставки средств нестероидных противовоспалительных лекарственных средств

Info

Publication number
EA200301321A1
EA200301321A1 EA200301321A EA200301321A EA200301321A1 EA 200301321 A1 EA200301321 A1 EA 200301321A1 EA 200301321 A EA200301321 A EA 200301321A EA 200301321 A EA200301321 A EA 200301321A EA 200301321 A1 EA200301321 A1 EA 200301321A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pharmaceutical compositions
dosage form
nonsteroid anti
release
coordinated delivery
Prior art date
Application number
EA200301321A
Other languages
English (en)
Other versions
EA006398B1 (ru
Inventor
Джон Р. Плачетка
Original Assignee
Поузен Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23134063&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200301321(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Поузен Инк. filed Critical Поузен Инк.
Publication of EA200301321A1 publication Critical patent/EA200301321A1/ru
Publication of EA006398B1 publication Critical patent/EA006398B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Настоящее изобретение относится к дозированным лекарственным формам, которые высвобождают агент, повышающий показатель pH желудочно-кишечного тракта нуждающегося субъекта, и затем нестероидное противовоспалительное лекарственное средство. Дозированная форма создана таким образом, что NSAID не высвобождается до тех пор, пока внутрижелудочный показатель pH не повысится до безопасного уровня. Данное изобретение относится также к способам лечения нуждающихся субъектов, которые включают введение защищающей желудок единичной дозированной формы с координированным высвобождением, представляющей комбинацию средства против артрита и аналгезирующего средства, с целью ослабления боли и других симптомов при снижении риска возникновения поражений желудочно-кишечного тракта, таких как язвы, эрозии и кровотечения.Отчет о международном поиске был опубликован 2003.06.26.
EA200301321A 2001-06-01 2002-05-31 Фармацевтические композиции для координированной доставки нестероидных противовоспалительных лекарственных средств EA006398B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29458801P 2001-06-01 2001-06-01
PCT/US2002/017105 WO2002098352A2 (en) 2001-06-01 2002-05-31 PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs

Publications (2)

Publication Number Publication Date
EA200301321A1 true EA200301321A1 (ru) 2004-06-24
EA006398B1 EA006398B1 (ru) 2005-12-29

Family

ID=23134063

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200301321A EA006398B1 (ru) 2001-06-01 2002-05-31 Фармацевтические композиции для координированной доставки нестероидных противовоспалительных лекарственных средств

Country Status (18)

Country Link
US (1) US6926907B2 (ru)
EP (3) EP2163241A1 (ru)
JP (1) JP4756823B2 (ru)
AT (1) ATE474559T1 (ru)
AU (3) AU2002305758B2 (ru)
BE (1) BE2011C016I2 (ru)
CA (1) CA2449098C (ru)
CY (1) CY1110842T1 (ru)
DE (1) DE60237087D1 (ru)
DK (1) DK1411900T4 (ru)
EA (1) EA006398B1 (ru)
ES (1) ES2348710T5 (ru)
IL (2) IL159129A0 (ru)
LU (1) LU91858I2 (ru)
MX (1) MXPA03011017A (ru)
NO (2) NO333836B1 (ru)
PT (1) PT1411900E (ru)
WO (1) WO2002098352A2 (ru)

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