|
CA2804840C
(en)
|
2010-07-22 |
2018-09-11 |
Gilead Sciences, Inc. |
Methods and compounds for treating paramyxoviridae virus infections
|
|
KR101939710B1
(ko)
|
2011-12-21 |
2019-01-17 |
노비라 테라퓨틱스, 인코포레이티드 |
B형 간염의 항바이러스성 제제
|
|
UA122385C2
(uk)
|
2012-08-28 |
2020-11-10 |
ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі |
Сульфамоїлариламіди та їх застосування як лікарських препаратів для лікування гепатиту b
|
|
DK2961732T3
(en)
|
2013-02-28 |
2017-07-10 |
Janssen Sciences Ireland Uc |
SULFAMOYLARYLAMIDS AND USE THEREOF AS MEDICINES TO TREAT HEPATITIS B
|
|
BR112015025052A2
(pt)
|
2013-04-03 |
2021-07-06 |
Janssen Sciences Ireland Uc |
derivados de n-fenil-carboxamida e o seu uso como medicamentos para o tratamento da hepatite b
|
|
PT2997019T
(pt)
|
2013-05-17 |
2018-11-21 |
Janssen Sciences Ireland Uc |
Derivados de sulfamoíltiofenamida e o seu uso como medicamentos para o tratamento da hepatite b
|
|
JO3603B1
(ar)
|
2013-05-17 |
2020-07-05 |
Janssen Sciences Ireland Uc |
مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
|
|
JP6533217B2
(ja)
*
|
2013-05-17 |
2019-06-19 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
Ｂ型肝炎ウイルス感染症の治療および予防のための６−架橋ヘテロアリールジヒドロピリミジン類
|
|
SG10201805033XA
(en)
|
2013-07-25 |
2018-07-30 |
Janssen Sciences Ireland Uc |
Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
|
ES2655518T3
(es)
|
2013-10-23 |
2018-02-20 |
Janssen Sciences Ireland Uc |
Derivados de carboxamida y su uso como medicamentos para el tratamiento de la hepatitis B
|
|
RU2697707C9
(ru)
|
2013-11-27 |
2019-10-03 |
Саншайн Лейк Фарма Ко., Лтд. |
Процессы приготовления производных соединений дигидропиримидина и их промежуточных продуктов
|
|
US10392349B2
(en)
|
2014-01-16 |
2019-08-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
|
ES2792848T3
(es)
|
2014-02-05 |
2020-11-12 |
Novira Therapeutics Inc |
Politerapia para el tratamiento de infecciones por VHB
|
|
UY35980A
(es)
|
2014-02-06 |
2015-08-31 |
Janssen Sciences Ireland Uc |
Derivados de sulfamoilpirrolamida como inhibidores del hbv y composiciones farmacéuticas que los contienen
|
|
EP3114128B1
(en)
*
|
2014-03-07 |
2019-01-02 |
F. Hoffmann-La Roche AG |
Novel 6-fused heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
|
EP3122747B1
(en)
|
2014-03-28 |
2020-05-20 |
North & South Brother Pharmacy Investment Company Limited |
Dihydropyrimidine compounds and their application in pharmaceuticals
|
|
CA2950807C
(en)
*
|
2014-05-30 |
2022-05-31 |
Medshine Discovery Inc. |
Dihydropyrimido fused ring derivative as hbv inhibitor
|
|
TWI698444B
(zh)
|
2014-10-29 |
2020-07-11 |
美商基利科學股份有限公司 |
製備核糖苷的方法
|
|
CN105859708B
(zh)
|
2015-02-07 |
2020-01-21 |
广东东阳光药业有限公司 |
二氢嘧啶衍生物的盐及其在药物中的应用
|
|
CR20170424A
(es)
|
2015-03-16 |
2018-01-26 |
Hoffmann La Roche |
Tratamiento combinado con un agonista de tlr7 y un inhibidor del ensamblaje de la cápsula del vhb
|
|
WO2016161268A1
(en)
|
2015-04-01 |
2016-10-06 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antviral agents
|
|
US10738035B2
(en)
|
2015-05-13 |
2020-08-11 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
|
WO2017011552A1
(en)
|
2015-07-13 |
2017-01-19 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
US10301255B2
(en)
|
2015-07-22 |
2019-05-28 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
EP4088718A1
(en)
|
2015-09-16 |
2022-11-16 |
Gilead Sciences, Inc. |
Methods for treating coronaviridae virus infections
|
|
WO2017049140A2
(en)
|
2015-09-18 |
2017-03-23 |
Wake Forest University Health Sciences |
Angiotensin (1-7) analogs and methods relating thereto
|
|
WO2017064156A1
(en)
|
2015-10-16 |
2017-04-20 |
F. Hoffmann-La Roche Ag |
Novel 6-fused and 2-heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
|
BR112018009009A8
(pt)
*
|
2015-11-03 |
2019-02-26 |
Hoffmann La Roche |
terapia combinada de um inibidor de formação de capsídeo hbv e um interferon
|
|
CA2914601A1
(en)
*
|
2015-12-11 |
2017-06-11 |
Wake Forest University Health Sciences |
Angiotensin-(1-7) analogs and methods relating thereto
|
|
WO2017108630A1
(en)
*
|
2015-12-21 |
2017-06-29 |
F. Hoffmann-La Roche Ag |
Combination therapy of an hbsag inhibitor and an hbv capsid assembly inhibitor
|
|
WO2017136403A1
(en)
*
|
2016-02-02 |
2017-08-10 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
AR107633A1
(es)
*
|
2016-02-19 |
2018-05-16 |
Hoffmann La Roche |
Procedimiento para la preparación del ácido 4-fenil-5-alcoxicarbonil-2-tiazol-2-il-1,4-dihidropirimidin-6-il-[metil]-3-oxo-5,6,8,8a-tetrahidro-1h-imidazo[1,5a]pirazin-2-il-carboxílico
|
|
WO2017140821A1
(en)
|
2016-02-19 |
2017-08-24 |
Novartis Ag |
Tetracyclic pyridone compounds as antivirals
|
|
PL3426245T3
(pl)
|
2016-03-07 |
2023-05-22 |
Enanta Pharmaceuticals, Inc. |
Środki przeciwwirusowe zapalenia wątroby typu b
|
|
MA44671A
(fr)
|
2016-04-15 |
2019-02-20 |
Janssen Sciences Ireland Uc |
Associations et méthodes comprenant un inhibiteur d'ensemble capside
|
|
DE202016102339U1
(de)
*
|
2016-05-03 |
2016-06-22 |
Freund Maschinenfabrik Gmbh & Co. Kg |
Gleitblock für ein Sägeband in einer Bandsägemaschine
|
|
JP6957518B2
(ja)
*
|
2016-05-20 |
2021-11-02 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
感染症の治療のための酸素、硫黄および窒素リンカーを有する新規ピラジン化合物
|
|
EP3468561A4
(en)
|
2016-06-10 |
2019-12-04 |
Enanta Pharmaceuticals, Inc. |
ANTIVIRAL AGENTS AGAINST HEPATITIS B
|
|
WO2017216686A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
8,9-fused 2-oxo-6,7-dihydropyrido-isoquinoline compounds as antivirals
|
|
WO2017216685A1
(en)
|
2016-06-16 |
2017-12-21 |
Novartis Ag |
Pentacyclic pyridone compounds as antivirals
|
|
JP6991213B2
(ja)
*
|
2016-07-29 |
2022-01-14 |
グアンジョウ・ルペン・ファーマシューティカル・カンパニー・リミテッド |
Ｈｂｖ感染の治療のための新規治療薬
|
|
EP3503894A1
(en)
|
2016-08-24 |
2019-07-03 |
H. Hoffnabb-La Roche Ag |
Combination therapy of an hbv capsid assembly inhibitor and a nucleos(t)ide analogue
|
|
KR102268448B1
(ko)
|
2016-09-02 |
2021-06-22 |
길리애드 사이언시즈, 인코포레이티드 |
톨 유사 수용체 조정제 화합물
|
|
WO2018045150A1
(en)
|
2016-09-02 |
2018-03-08 |
Gilead Sciences, Inc. |
4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
|
|
WO2018047109A1
(en)
|
2016-09-09 |
2018-03-15 |
Novartis Ag |
Polycyclic pyridone compounds as antivirals
|
|
WO2018050571A1
(en)
*
|
2016-09-13 |
2018-03-22 |
F. Hoffmann-La Roche Ag |
Combined treatment with a tlr7 agonist and an hbv capsid assembly inhibitor
|
|
SG11201903042VA
(en)
|
2016-10-14 |
2019-05-30 |
Precision Biosciences Inc |
Engineered meganucleases specific for recognition sequences in the hepatitis b virus genome
|
|
WO2018073753A1
(en)
|
2016-10-18 |
2018-04-26 |
Novartis Ag |
Fused tetracyclic pyridone compounds as antivirals
|
|
JP7113009B2
(ja)
|
2016-11-07 |
2022-08-04 |
アービュタス バイオファーマ コーポレイション |
置換ピリジノン含有三環式化合物およびそれを使用する方法
|
|
US11166954B2
(en)
|
2016-11-18 |
2021-11-09 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
Dihydropyrimidine compound and preparation method and use thereof
|
|
EP3508483B1
(en)
*
|
2016-11-18 |
2021-10-06 |
Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. |
Dihydropyrimidine compound and preparation method and use thereof
|
|
CN108341810B
(zh)
*
|
2017-01-23 |
2022-01-18 |
上海长森药业有限公司 |
环硫脲类化合物及其用途
|
|
TWI714820B
(zh)
|
2017-01-31 |
2021-01-01 |
美商基利科學股份有限公司 |
替諾福韋艾拉酚胺(tenofovir alafenamide)之晶型
|
|
CN116036112A
(zh)
|
2017-03-14 |
2023-05-02 |
吉利德科学公司 |
治疗猫冠状病毒感染的方法
|
|
WO2018172852A1
(en)
|
2017-03-21 |
2018-09-27 |
Arbutus Biopharma Corporation |
Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same
|
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
|
AR111419A1
(es)
|
2017-04-27 |
2019-07-10 |
Novartis Ag |
Compuestos fusionados de indazol piridona como antivirales
|
|
AU2018262501B2
(en)
|
2017-05-01 |
2020-12-10 |
Gilead Sciences, Inc. |
Crystalline forms of (S) 2 ethylbutyl 2 (((S) (((2R,3S,4R,5R) 5 (4 aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy) phosphoryl)amino)propanoate
|
|
JP7260488B2
(ja)
*
|
2017-06-26 |
2023-04-18 |
サンシャイン・レイク・ファーマ・カンパニー・リミテッド |
ジヒドロピリミジン化合物、及び医薬におけるその使用
|
|
AU2018291688B2
(en)
|
2017-06-27 |
2022-02-03 |
Janssen Pharmaceutica Nv |
Heteroaryldihydropyrimidine derivatives and methods of treating hepatitis B infections
|
|
US10675296B2
(en)
|
2017-07-11 |
2020-06-09 |
Gilead Sciences, Inc. |
Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections
|
|
JP7221277B2
(ja)
|
2017-08-28 |
2023-02-13 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
Ｂ型肝炎抗ウイルス剤
|
|
JP7202373B2
(ja)
*
|
2017-10-18 |
2023-01-11 |
サンシャイン・レイク・ファーマ・カンパニー・リミテッド |
ジヒドロピリミジン化合物、及び医薬におけるその使用
|
|
AU2018361364B2
(en)
|
2017-11-02 |
2020-11-26 |
Aicuris Gmbh & Co. Kg |
Novel, highly active amino-thiazole substituted indole-2-carboxamides active against the hepatitis B virus (HBV)
|
|
SG11202003746UA
(en)
|
2017-11-02 |
2020-05-28 |
Aicuris Gmbh & Co Kg |
Novel, highly active pyrazolo-piperidine substituted indole-2-carboxamides active against the hepatitis b virus (hbv)
|
|
US20210079015A1
(en)
|
2017-11-17 |
2021-03-18 |
Novartis Ag |
Novel dihydroisoxazole compounds and their use for the treatment of hepatitis b
|
|
US10428070B2
(en)
|
2017-12-06 |
2019-10-01 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
US10723733B2
(en)
|
2017-12-06 |
2020-07-28 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
US10966999B2
(en)
|
2017-12-20 |
2021-04-06 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
WO2019123285A1
(en)
|
2017-12-20 |
2019-06-27 |
Novartis Ag |
Fused tricyclic pyrazolo-dihydropyrazinyl-pyridone compounds as antivirals
|
|
US11203610B2
(en)
|
2017-12-20 |
2021-12-21 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2′3′ cyclic dinucleotides with phosphonate bond activating the sting adaptor protein
|
|
US20220135590A1
(en)
*
|
2017-12-21 |
2022-05-05 |
Janssen Science Ireland Unlimited Company |
Isoxazole compounds for the treatment of diseases associated with hbv infections
|
|
EP3732177B1
(en)
|
2017-12-28 |
2021-11-17 |
F. Hoffmann-La Roche AG |
Dihydropyrimidinylthiazole for the treatment and prophylaxis of hepatitis b virus infection
|
|
WO2019143902A2
(en)
|
2018-01-22 |
2019-07-25 |
Enanta Pharmaceuticals, Inc. |
Substituted heterocycles as antiviral agents
|
|
BR102019002873A2
(pt)
|
2018-02-13 |
2019-09-10 |
Gilead Sciences Inc |
inibidores de pd-1/pd-l1
|
|
WO2019165374A1
(en)
|
2018-02-26 |
2019-08-29 |
Gilead Sciences, Inc. |
Substituted pyrrolizine compounds as hbv replication inhibitors
|
|
JP2021514982A
(ja)
|
2018-02-28 |
2021-06-17 |
ノバルティス アーゲー |
インドール−２−カルボニル化合物及びｂ型肝炎治療のためのそれらの使用
|
|
JP2021515769A
(ja)
|
2018-03-14 |
2021-06-24 |
ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー |
カプシド集合調節剤の投薬レジメン
|
|
WO2019191166A1
(en)
|
2018-03-29 |
2019-10-03 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
EP3774883A1
(en)
|
2018-04-05 |
2021-02-17 |
Gilead Sciences, Inc. |
Antibodies and fragments thereof that bind hepatitis b virus protein x
|
|
TW202005654A
(zh)
|
2018-04-06 |
2020-02-01 |
捷克科學院有機化學與生物化學研究所 |
２，２，─環二核苷酸
|
|
TWI818007B
(zh)
|
2018-04-06 |
2023-10-11 |
捷克科學院有機化學與生物化學研究所 |
2'3'-環二核苷酸
|
|
TWI833744B
(zh)
|
2018-04-06 |
2024-03-01 |
捷克科學院有機化學與生物化學研究所 |
3'3'-環二核苷酸
|
|
TW201945388A
(zh)
|
2018-04-12 |
2019-12-01 |
美商精密生物科學公司 |
對b型肝炎病毒基因體中之識別序列具有特異性之最佳化之經工程化巨核酸酶
|
|
KR102591947B1
(ko)
|
2018-04-19 |
2023-10-25 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
|
TW202014193A
(zh)
|
2018-05-03 |
2020-04-16 |
捷克科學院有機化學與生物化學研究所 |
包含碳環核苷酸之2’3’－環二核苷酸
|
|
TWI809427B
(zh)
|
2018-07-13 |
2023-07-21 |
美商基利科學股份有限公司 |
Pd‐1/pd‐l1抑制劑
|
|
TW202416959A
(zh)
|
2018-07-27 |
2024-05-01 |
加拿大商愛彼特生物製藥公司 |
經取代四氫環戊[c]吡咯、經取代二氫吡咯𠯤，其類似物及使用其之方法
|
|
WO2020028097A1
(en)
|
2018-08-01 |
2020-02-06 |
Gilead Sciences, Inc. |
Solid forms of (r)-11-(methoxymethyl)-12-(3-methoxypropoxy)-3,3-dimethyl-8-0x0-2,3,8,13b-tetrahydro-1h-pyrido[2,1-a]pyrrolo[1,2-c] phthalazine-7-c arboxylic acid
|
|
US11053235B2
(en)
|
2018-08-09 |
2021-07-06 |
Janssen Sciences Ireland Unlimited Company |
Substituted 1,4-dihydropyrimidines for the treatment of HBV infection or HBV-induced diseases
|
|
WO2020061435A1
(en)
|
2018-09-21 |
2020-03-26 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocycles as antiviral agents
|
|
EP3870566A1
(en)
|
2018-10-24 |
2021-09-01 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
|
TWI721624B
(zh)
|
2018-10-31 |
2021-03-11 |
美商基利科學股份有限公司 |
經取代之6-氮雜苯并咪唑化合物
|
|
EP3873488A4
(en)
|
2018-10-31 |
2022-08-03 |
The University of Sydney |
COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRUS INFECTION
|
|
EP3873903B1
(en)
|
2018-10-31 |
2024-01-24 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds as hpk1 inhibitors
|
|
UY38439A
(es)
|
2018-11-02 |
2020-05-29 |
Aicuris Gmbh & Co Kg |
Novedosas urea 6,7-dihidro-4h-pirazolo[4,3-c]piridinas activas contra el virus de la hepatitis b (vhb)
|
|
UY38435A
(es)
|
2018-11-02 |
2020-05-29 |
Aicuris Gmbh & Co Kg |
Nuevas urea 6,7-dihidro-4h-pirazol[1,5-a] pirazinas activas contra el virus de la hepatitis b (vhb)
|
|
AR117189A1
(es)
|
2018-11-02 |
2021-07-21 |
Aicuris Gmbh & Co Kg |
Derivados de 6,7-dihidro-4h-pirazolo[1,5-a]pirazin indol-2-carboxamidas activos contra el virus de la hepatitis b (vhb)
|
|
AR116947A1
(es)
|
2018-11-02 |
2021-06-30 |
Aicuris Gmbh & Co Kg |
Derivados de urea 6,7-dihidro-4h-pirazolo[1,5-a]pirazinas-indol-2-carboxamidas activas contra el virus de la hepatitis b (vhb)
|
|
AU2019373679A1
(en)
|
2018-11-02 |
2021-05-27 |
Aicuris Gmbh & Co. Kg |
Novel urea 6,7-dihydro-4H-thiazolo(5,4-c)pyridines active against the hepatitis B virus (HBV)
|
|
UY38437A
(es)
|
2018-11-02 |
2020-05-29 |
Aicuris Gmbh & Co Kg |
Nuevas urea 6,7-dihidro-4h-pirazolo[1,5-a]pirazinas activas contra el virus de la hepatitis b (hbv)
|
|
BR112021009854A2
(pt)
|
2018-11-21 |
2021-08-17 |
Enanta Pharmaceuticals, Inc. |
heterociclos funcionalizados como agentes antivirais
|
|
TW202415643A
(zh)
|
2018-12-12 |
2024-04-16 |
加拿大商愛彼特生物製藥公司 |
經取代之芳基甲基脲類及雜芳基甲基脲類、其類似物及其使用方法
|
|
TW202035412A
(zh)
*
|
2018-12-20 |
2020-10-01 |
比利時商健生藥品公司 |
雜芳基二氫嘧啶衍生物和治療ｂ型肝炎感染之方法
|
|
CA3124317A1
(en)
*
|
2018-12-20 |
2020-06-25 |
Janssen Pharmaceutica Nv |
Heteroaryldihydropyrimidine derivatives and methods of treating hepatitis b infections
|
|
CN113166154B
(zh)
*
|
2018-12-25 |
2022-12-27 |
广东东阳光药业有限公司 |
氘代二氢嘧啶类化合物及其在药物中的应用
|
|
BR112021015618A2
(pt)
|
2019-02-22 |
2021-10-05 |
Janssen Sciences Ireland Unlimited Company |
Derivados de amida úteis no tratamento da infecção pelo hbv ou doenças induzidas pelo hbv
|
|
US11766447B2
(en)
|
2019-03-07 |
2023-09-26 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
3′3′-cyclic dinucleotide analogue comprising a cyclopentanyl modified nucleotide as sting modulator
|
|
KR20210137518A
(ko)
|
2019-03-07 |
2021-11-17 |
인스티튜트 오브 오가닉 케미스트리 앤드 바이오케미스트리 에이에스 씨알 브이.브이.아이. |
3'3'-사이클릭 다이뉴클레오티드 및 이의 프로드럭
|
|
AU2020231201A1
(en)
|
2019-03-07 |
2021-08-26 |
Institute Of Organic Chemistry And Biochemistry Ascr, V.V.I. |
2'3'-cyclic dinucleotides and prodrugs thereof
|
|
AU2020249331A1
(en)
|
2019-03-25 |
2021-09-23 |
F. Hoffmann-La Roche Ag |
Solid forms of a compound of HBV core protein allosteric modifier
|
|
CN111825676B
(zh)
*
|
2019-04-15 |
2023-10-17 |
广东东阳光药业股份有限公司 |
二氢嘧啶类化合物及其在药物中的应用
|
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TW202212339A
(zh)
|
2019-04-17 |
2022-04-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TW202104210A
(zh)
|
2019-04-17 |
2021-02-01 |
美商基利科學股份有限公司 |
Hiv蛋白酶抑制劑
|
|
CU20210089A7
(es)
|
2019-04-30 |
2022-06-06 |
Aicuris Gmbh & Co Kg |
Compuestos derivados de fenil y piridil ureas activas contra el virus de la hepatitis b (vhb)
|
|
WO2020221824A1
(en)
|
2019-04-30 |
2020-11-05 |
Aicuris Gmbh & Co. Kg |
Novel indolizine-2-carboxamides active against the hepatitis b virus (hbv)
|
|
KR20220003023A
(ko)
|
2019-04-30 |
2022-01-07 |
아이쿠리스 게엠베하 운트 코. 카게 |
B형 간염 바이러스 (hbv)에 대해 활성인 신규 옥살릴 피페라진
|
|
US20220194951A1
(en)
*
|
2019-04-30 |
2022-06-23 |
Sunshine Lake Pharma Co., Ltd. |
Dihydropyrimidine compound and application thereof as drug
|
|
EP3962914A1
(en)
|
2019-04-30 |
2022-03-09 |
AiCuris GmbH & Co. KG |
Novel indole-2-carboxamides active against the hepatitis b virus (hbv)
|
|
WO2020225230A1
(en)
|
2019-05-06 |
2020-11-12 |
Janssen Sciences Ireland Unlimited Company |
Amide derivatives useful in the treatment of hbv infection or hbv-induced diseases
|
|
CN113825758B
(zh)
*
|
2019-05-14 |
2023-08-01 |
正大天晴药业集团股份有限公司 |
抗HBV的四氢异噁唑并[4,3-c]吡啶类化合物的晶型
|
|
WO2020237025A1
(en)
|
2019-05-23 |
2020-11-26 |
Gilead Sciences, Inc. |
Substituted exo-methylene-oxindoles which are hpk1/map4k1 inhibitors
|
|
US11236111B2
(en)
|
2019-06-03 |
2022-02-01 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
WO2020247575A1
(en)
|
2019-06-04 |
2020-12-10 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
|
US11760755B2
(en)
|
2019-06-04 |
2023-09-19 |
Enanta Pharmaceuticals, Inc. |
Hepatitis B antiviral agents
|
|
BR112021024398A2
(pt)
*
|
2019-06-06 |
2022-01-18 |
Hoffmann La Roche |
Processo alternativo para a preparação de ácido 4-fenil-5-alcoxicarbonil-2-tiazol-2-il-1,4-di-hidropirimidin-6-il]metil]-3-oxo-5,6,8,8a-tetra-hidro-1h-imidazo[1,5-a]pirazin-2-il]-carboxílico
|
|
WO2020255017A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
|
|
WO2020255016A1
(en)
|
2019-06-18 |
2020-12-24 |
Janssen Sciences Ireland Unlimited Company |
Combination of hepatitis b virus (hbv) vaccines and dihydropyrimidine derivatives as capsid assembly modulators
|
|
AU2020301161B2
(en)
|
2019-06-25 |
2023-10-26 |
Gilead Sciences, Inc. |
FLT3L-Fc fusion proteins and methods of use
|
|
US11738019B2
(en)
|
2019-07-11 |
2023-08-29 |
Enanta Pharmaceuticals, Inc. |
Substituted heterocycles as antiviral agents
|
|
WO2021011891A1
(en)
|
2019-07-18 |
2021-01-21 |
Gilead Sciences, Inc. |
Long-acting formulations of tenofovir alafenamide
|
|
TW202122392A
(zh)
*
|
2019-07-31 |
2021-06-16 |
愛爾蘭商健生科學愛爾蘭無限公司 |
二氫嘧啶衍生物及其於治療ｈｂｖ感染或ｈｂｖ誘發的疾病之用途
|
|
AU2020322598A1
(en)
*
|
2019-07-31 |
2022-03-24 |
Janssen Sciences Ireland Unlimited Company |
Dihydropyrimidine derivatives and uses thereof in the treatment of HBV infection or of HBV-induced diseases
|
|
EP4017476A1
(en)
|
2019-08-19 |
2022-06-29 |
Gilead Sciences, Inc. |
Pharmaceutical formulations of tenofovir alafenamide
|
|
US11236108B2
(en)
|
2019-09-17 |
2022-02-01 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocycles as antiviral agents
|
|
WO2021053126A1
(en)
|
2019-09-20 |
2021-03-25 |
F. Hoffmann-La Roche Ag |
Method of treating hbv infection using a core protein allosteric modulator
|
|
CN114555799A
(zh)
|
2019-09-30 |
2022-05-27 |
吉利德科学公司 |
Hbv疫苗和治疗hbv的方法
|
|
CN112707910A
(zh)
*
|
2019-10-24 |
2021-04-27 |
广东东阳光药业有限公司 |
二氢嘧啶类化合物及其在药物中的应用
|
|
WO2021113765A1
(en)
|
2019-12-06 |
2021-06-10 |
Precision Biosciences, Inc. |
Optimized engineered meganucleases having specificity for a recognition sequence in the hepatitis b virus genome
|
|
CA3160543A1
(en)
*
|
2019-12-20 |
2021-06-24 |
Gang Deng |
Heteroaryldihydropyrimidine derivatives and methods of treating hepatitis b infections
|
|
BR112022012625A2
(pt)
|
2019-12-24 |
2022-09-06 |
Carna Biosciences Inc |
Compostos moduladores de diacilglicerol quinase
|
|
US20230044958A1
(en)
|
2019-12-24 |
2023-02-09 |
Hoffmann-La Roche Inc. |
Method of treating virus infection using a tlr7 agonist
|
|
AU2020415322A1
(en)
|
2019-12-24 |
2022-06-16 |
F. Hoffmann-La Roche Ag |
Pharmaceutical combination of antiviral agents targeting HBV and/or an immune modulator for treatment of HBV
|
|
EP4081639A1
(en)
|
2019-12-24 |
2022-11-02 |
F. Hoffmann-La Roche AG |
Pharmaceutical combination of a therapeutic oligonucleotide targeting hbv and a tlr7 agonist for treatment of hbv
|
|
CN118766947A
(zh)
|
2020-01-27 |
2024-10-15 |
吉利德科学公司 |
用于治疗SARS CoV-2感染的方法
|
|
EP4118085A2
(en)
|
2020-03-12 |
2023-01-18 |
Gilead Sciences, Inc. |
Methods of preparing 1'-cyano nucleosides
|
|
US11802125B2
(en)
|
2020-03-16 |
2023-10-31 |
Enanta Pharmaceuticals, Inc. |
Functionalized heterocyclic compounds as antiviral agents
|
|
AU2021237718B2
(en)
|
2020-03-20 |
2023-09-21 |
Gilead Sciences, Inc. |
Prodrugs of 4'-C-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same
|
|
CA3172483A1
(en)
|
2020-04-06 |
2021-10-14 |
Scott Ellis |
Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
|
|
BR112022021928A2
(pt)
|
2020-04-28 |
2022-12-13 |
Hoffmann La Roche |
Processo para a preparação de um ácido piperazina-2-carboxílico quiral
|
|
US11975012B2
(en)
|
2020-05-29 |
2024-05-07 |
Gilead Sciences, Inc. |
Remdesivir treatment methods
|
|
CR20220675A
(es)
|
2020-06-24 |
2023-02-15 |
Gilead Sciences Inc |
Análogos de nucleósido de 1´- ciano y usos de los mismos
|
|
EP4182032A1
(en)
|
2020-07-14 |
2023-05-24 |
F. Hoffmann-La Roche AG |
Hydroisoquinoline or hydronaphthyridine compounds for the treatment of autoimmune disease
|
|
MX2023001443A
(es)
|
2020-08-05 |
2023-04-14 |
Hoffmann La Roche |
Tratamiento con oligonucleotidos de pacientes con hepatitis b.
|
|
CR20230071A
(es)
|
2020-08-07 |
2023-04-11 |
Gilead Sciences Inc |
Profármacos de análogos de nucleótidos de fosfonamida y su uso farmacéutico
|
|
IL300412A
(en)
|
2020-08-24 |
2023-04-01 |
Gilead Sciences Inc |
Phospholipid compounds and their uses
|
|
JP7560659B2
(ja)
|
2020-08-27 |
2024-10-02 |
ギリアード サイエンシーズ， インコーポレイテッド |
ウイルス感染症の治療のための化合物及び方法
|
|
CN111892544A
(zh)
*
|
2020-08-31 |
2020-11-06 |
南通大学 |
一种3-（氨基甲基）-4-（4-氟苯基）哌嗪-1-羧酸叔丁酯及其合成方法
|
|
WO2022052923A1
(zh)
*
|
2020-09-08 |
2022-03-17 |
和博医药有限公司 |
二氢嘧啶类化合物、其应用
|
|
WO2022078479A1
(en)
*
|
2020-10-16 |
2022-04-21 |
Janssen Pharmaceuticals, Inc. |
Combination therapy for treating hepatitis b virus infection
|
|
TWI811812B
(zh)
|
2020-10-16 |
2023-08-11 |
美商基利科學股份有限公司 |
磷脂化合物及其用途
|
|
TW202406932A
(zh)
|
2020-10-22 |
2024-02-16 |
美商基利科學股份有限公司 |
介白素2-Fc融合蛋白及使用方法
|
|
CN114573589B
(zh)
*
|
2020-11-30 |
2023-10-20 |
广东东阳光药业股份有限公司 |
二氢嘧啶衍生物的盐、复合物以及它们在药物中的应用
|
|
CN114621219A
(zh)
*
|
2020-12-09 |
2022-06-14 |
上海维申医药有限公司 |
一种二氢嘧啶类化合物、其制备方法及应用
|
|
US20240246978A1
(en)
*
|
2021-02-05 |
2024-07-25 |
Hepagene Therapeutics (HK) Limited |
Phenyldihydropyrimidine compound and use thereof
|
|
CN114853761A
(zh)
*
|
2021-02-05 |
2022-08-05 |
刘沛 |
一种含有二氢嘧啶的双功能衍生物及其用途
|
|
US20240166649A1
(en)
*
|
2021-02-09 |
2024-05-23 |
Shanghai Visonpharma Co., Ltd. |
Dihydropyrimidine compound, preparation method therefor and application thereof
|
|
CA3217107A1
(en)
|
2021-05-13 |
2022-11-17 |
Daniel J. CLOUTIER |
Combination of a tlr8 modulating compound and anti-hbv sirna therapeutics
|
|
US20230000873A1
(en)
|
2021-05-26 |
2023-01-05 |
Gilead Sciences, Inc. |
Phospholipid formulations of 1'-cyano substituted carba-nucleoside analogs
|
|
AU2022299051A1
(en)
|
2021-06-23 |
2023-12-07 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
|
KR20240025616A
(ko)
|
2021-06-23 |
2024-02-27 |
길리애드 사이언시즈, 인코포레이티드 |
다이아실글리세롤 키나제 조절 화합물
|
|
JP2024522594A
(ja)
|
2021-06-23 |
2024-06-21 |
ギリアード サイエンシーズ， インコーポレイテッド |
ジアシルグリセロールキナーゼ調節化合物
|
|
KR20240023628A
(ko)
|
2021-06-23 |
2024-02-22 |
길리애드 사이언시즈, 인코포레이티드 |
디아실글리세롤 키나제 조절 화합물
|
|
US12116380B2
(en)
|
2021-08-18 |
2024-10-15 |
Gilead Sciences, Inc. |
Phospholipid compounds and methods of making and using the same
|
|
CN114702497B
(zh)
*
|
2021-12-23 |
2023-03-21 |
华南理工大学 |
二氢嘧啶衍生物的晶型及其制备方法和在药物中的应用
|
|
CN114702498B
(zh)
*
|
2021-12-23 |
2022-12-16 |
华南理工大学 |
二氢嘧啶衍生物的酸加成盐及其在药物中的应用
|
|
AU2023227470A1
(en)
|
2022-03-02 |
2024-08-29 |
Gilead Sciences, Inc. |
Compounds and methods for treatment of viral infections
|
|
MX2024010591A
(es)
|
2022-03-02 |
2024-09-06 |
Gilead Sciences Inc |
Compuestos y metodos para el tratamiento de infecciones virales.
|
|
MX2024010671A
(es)
|
2022-03-03 |
2024-09-11 |
Gilead Sciences Inc |
Compuestos antivirales y metodos de elaboracion y uso de los mismos.
|
|
KR20240155327A
(ko)
|
2022-03-03 |
2024-10-28 |
길리애드 사이언시즈, 인코포레이티드 |
항바이러스 화합물 및 이의 제조와 사용 방법
|
|
TW202415386A
(zh)
|
2022-06-06 |
2024-04-16 |
美商基利科學股份有限公司 |
用於治療病毒感染之方法
|
|
US20240051962A1
(en)
|
2022-06-29 |
2024-02-15 |
Gilead Sciences, Inc. |
Solid forms of a nucleoside analogue and uses thereof
|
|
US20240043466A1
(en)
|
2022-06-30 |
2024-02-08 |
Gilead Sciences, Inc. |
Solid forms of a nucleoside analogue and uses thereof
|
|
US20240309028A1
(en)
|
2023-02-16 |
2024-09-19 |
Gilead Sciences, Inc. |
Phospholipid compounds and methods of making and using the same
|
|
WO2024218026A1
(en)
|
2023-04-17 |
2024-10-24 |
F. Hoffmann-La Roche Ag |
Process for the preparation of 4-hydroxy-4,5-dihydrothiazole-2-carbonitrile and derivatives thereof
|