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DK538888D0 - Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat - Google Patents

Anvendelse af castanosperminestere til fremstilling af et farmaceutisk praeparat

Info

Publication number
DK538888D0
DK538888D0 DK538888A DK538888A DK538888D0 DK 538888 D0 DK538888 D0 DK 538888D0 DK 538888 A DK538888 A DK 538888A DK 538888 A DK538888 A DK 538888A DK 538888 D0 DK538888 D0 DK 538888D0
Authority
DK
Denmark
Prior art keywords
preparation
castanosperminesters
pharmaceutical
pharmaceutical preparation
aids
Prior art date
Application number
DK538888A
Other languages
English (en)
Other versions
DK538888A (da
DK172788B1 (da
Inventor
Paul S Liu
Sai P Sunkara
Terry L Bowlin
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK538888D0 publication Critical patent/DK538888D0/da
Publication of DK538888A publication Critical patent/DK538888A/da
Application granted granted Critical
Publication of DK172788B1 publication Critical patent/DK172788B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK198805388A 1987-09-29 1988-09-28 Anvendelse af castanosperminestere til fremstilling af et farmaceutisk præparat DK172788B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/102,070 US5004746A (en) 1987-09-29 1987-09-29 Anti-retroviral castanospermine esters
US10207087 1987-09-29

Publications (3)

Publication Number Publication Date
DK538888D0 true DK538888D0 (da) 1988-09-28
DK538888A DK538888A (da) 1989-03-30
DK172788B1 DK172788B1 (da) 1999-07-19

Family

ID=22287973

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198805388A DK172788B1 (da) 1987-09-29 1988-09-28 Anvendelse af castanosperminestere til fremstilling af et farmaceutisk præparat

Country Status (12)

Country Link
US (1) US5004746A (da)
EP (1) EP0309952B1 (da)
JP (1) JP2761898B2 (da)
KR (1) KR960009416B1 (da)
AT (1) ATE107506T1 (da)
AU (1) AU614993B2 (da)
DE (1) DE3850335T2 (da)
DK (1) DK172788B1 (da)
ES (1) ES2058201T3 (da)
IE (1) IE64311B1 (da)
PH (1) PH24431A (da)
ZA (1) ZA887160B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987003903A1 (en) * 1985-12-23 1987-07-02 Fred Hutchinson Cancer Research Center Regulating retroviral replication, infection, and pathogenesis
US4952585A (en) * 1988-12-15 1990-08-28 Merrell Dow Pharmaceuticals Inc. Castanospermine esters in the inhibition of tumor metastasis
AU628228B2 (en) * 1989-10-17 1992-09-10 Merrell Dow Pharmaceuticals Inc. Esters of castanospermine in the treatment of cerebral malaria
US5214050A (en) * 1989-10-17 1993-05-25 Merrell Dow Pharmaceuticals Inc. Esters of castanospermine in the treatment of cerebral malaria
GB8924292D0 (en) * 1989-10-27 1989-12-13 Novalal Ltd The production of a novel dimer chemical product"novo dimers"by the polymersation of indolizidine alkaloids using cyclo dextrin glucosyl transferase
US5028614A (en) * 1990-03-30 1991-07-02 Merrell Dow Pharmaceuticals Inc. Hydroxymethyl-indolizidines and quinolizidines and their use as α-glucosidase I inhibitors
GB9027433D0 (en) * 1990-12-18 1991-02-06 Merrell Dow Pharma Anti-herpes castanospermine esters
US5939430A (en) * 1993-02-22 1999-08-17 Merrell Pharmaceuticals Inc. Combinations of retroviral inhibitors
GB9303518D0 (en) * 1993-02-22 1993-04-07 Merrell Dow Pharma Combinations of retroviral inhibitors
US5959111A (en) * 1997-05-22 1999-09-28 Hoechst Marion Roussel, Inc. Process for preparing 6-0-monoesters of castanospermine
DE69821757T2 (de) * 1997-05-22 2005-01-13 Aventis Pharmaceuticals Inc. Verfahren zur herstellung von 6-0-monoestern von castanospermine
GB0110832D0 (en) * 2001-05-03 2001-06-27 Virogen Ltd Antiviral compounds
CN101014341A (zh) * 2004-08-13 2007-08-08 麦根克斯有限公司 治疗或预防嗜肝dna病毒科病毒感染的组合物和方法
WO2006037227A1 (en) * 2004-10-06 2006-04-13 Migenix Inc. Combination anti-viral compositions comprising castanospermine and methods of use
US20080138351A1 (en) * 2006-08-02 2008-06-12 United Therapeutics Corporation Liposome treatment of viral infections
EP2282723A2 (en) * 2008-03-26 2011-02-16 University of Oxford Endoplasmic reticulum targeting liposomes
WO2010109330A2 (en) * 2009-03-27 2010-09-30 University Of Oxford Cholesterol level lowering liposomes
US11369592B2 (en) 2020-02-21 2022-06-28 Florida State University Research Foundation, Inc. Treatment of human coronavirus infections using alpha-glucosidase glycoprotein processing inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987003903A1 (en) * 1985-12-23 1987-07-02 Fred Hutchinson Cancer Research Center Regulating retroviral replication, infection, and pathogenesis
ZA883925B (en) * 1987-06-08 1989-02-22 Merrell Dow Pharma Inhibitors of glycoprotein processing having anti-retroviral activity
CA1315276C (en) * 1987-07-02 1993-03-30 Paul S. Liu Castanospermine esters and glycosides
US4952585A (en) * 1988-12-15 1990-08-28 Merrell Dow Pharmaceuticals Inc. Castanospermine esters in the inhibition of tumor metastasis

Also Published As

Publication number Publication date
DE3850335T2 (de) 1994-10-13
EP0309952A3 (en) 1990-09-26
JPH01106821A (ja) 1989-04-24
AU2280288A (en) 1989-04-06
DK538888A (da) 1989-03-30
KR960009416B1 (en) 1996-07-19
AU614993B2 (en) 1991-09-19
PH24431A (en) 1990-06-25
IE882933L (en) 1989-03-29
DK172788B1 (da) 1999-07-19
US5004746A (en) 1991-04-02
IE64311B1 (en) 1995-07-26
JP2761898B2 (ja) 1998-06-04
EP0309952A2 (en) 1989-04-05
ATE107506T1 (de) 1994-07-15
EP0309952B1 (en) 1994-06-22
ZA887160B (en) 1989-05-30
ES2058201T3 (es) 1994-11-01
KR890004701A (ko) 1989-05-09
DE3850335D1 (de) 1994-07-28

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