DK383984A - Fremgangsmaade til fremstilling af sekretin - Google Patents

Fremgangsmaade til fremstilling af sekretin Download PDF

Info

Publication number: DK383984A
Authority: DK; Denmark
Prior art keywords: secretin; secretylglycine; genetic engineering; gene; enzymatically
Prior art date: 1983-08-10

Application number

DK383984A

Other languages

English (en)

Other versions

DK383984D0 (da

Inventor

Wolfgang Koenig

Joachim Engels

Eugen Uhlmann

Waldemar Wetekam

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-08-10

Filing date

1984-08-09

Publication date

1985-02-11

1984-08-09 Application filed by Hoechst Ag filed Critical Hoechst Ag

1984-08-09 Publication of DK383984D0 publication Critical patent/DK383984D0/da

1985-02-11 Publication of DK383984A publication Critical patent/DK383984A/da

Links

238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1
108010086019 Secretin Proteins 0.000 abstract 3
102100037505 Secretin Human genes 0.000 abstract 3
229960002101 secretin Drugs 0.000 abstract 3
OWMZNFCDEHGFEP-NFBCVYDUSA-N secretin human Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O)[C@@H](C)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC=1NC=NC=1)[C@@H](C)O)C1=CC=CC=C1 OWMZNFCDEHGFEP-NFBCVYDUSA-N 0.000 abstract 3
238000010353 genetic engineering Methods 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
150000001735 carboxylic acids Chemical class 0.000 abstract 1
238000006243 chemical reaction Methods 0.000 abstract 1
238000003776 cleavage reaction Methods 0.000 abstract 1
ATDGTVJJHBUTRL-UHFFFAOYSA-N cyanogen bromide Chemical compound BrC#N ATDGTVJJHBUTRL-UHFFFAOYSA-N 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1
108020001507 fusion proteins Proteins 0.000 abstract 1
102000037865 fusion proteins Human genes 0.000 abstract 1
DXMZNKNJOBUNRO-UHFFFAOYSA-N glycyl radical Chemical group N[CH]C(O)=O DXMZNKNJOBUNRO-UHFFFAOYSA-N 0.000 abstract 1
108090000765 processed proteins & peptides Proteins 0.000 abstract 1
230000007017 scission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/645—Secretins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
Biomedical Technology (AREA)
Zoology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biotechnology (AREA)
Wood Science & Technology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
Plant Pathology (AREA)
Physics & Mathematics (AREA)
Endocrinology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Microbiology (AREA)
Medicinal Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Saccharide Compounds (AREA)
Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
Tires In General (AREA)
Control Of Vending Devices And Auxiliary Devices For Vending Devices (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK383984A 1983-08-10 1984-08-09 Fremgangsmaade til fremstilling af sekretin DK383984A (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19833328793 DE3328793A1 (de)	1983-08-10	1983-08-10	Herstellung von sekretin

Publications (2)

Publication Number	Publication Date
DK383984D0 DK383984D0 (da)	1984-08-09
DK383984A true DK383984A (da)	1985-02-11

Family

ID=6206183

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK383984A DK383984A (da)	1983-08-10	1984-08-09	Fremgangsmaade til fremstilling af sekretin

Country Status (8)

Country	Link
US (1)	US4711847A (da)
EP (1)	EP0136472B1 (da)
JP (1)	JPS6069098A (da)
AT (1)	ATE40717T1 (da)
CA (1)	CA1224167A (da)
DE (2)	DE3328793A1 (da)
DK (1)	DK383984A (da)
GR (1)	GR80059B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5759815A (en) *	1988-02-11	1998-06-02	Creative Biomolecules, Inc.	Production of platelet derived growth factor (PDGF) an muteins thereof
JP2753274B2 (ja) *	1988-08-24	1998-05-18	株式会社三和化学研究所	モチリン様ポリペプチドの製法並びにそのための組換えｄｎａ及び発現用プラスミド
AU748147B2 (en)	1997-05-19	2002-05-30	Repligen Corporation	Method for assisting in differential diagnosis and treatment of autistic syndromes
US6197746B1 (en)	1998-05-19	2001-03-06	Repligen Corporation	Method of using secretin for treating autism
US20030190740A1 (en)	1998-10-13	2003-10-09	The University Of Georgia Research Foundation, Inc	Stabilized bioactive peptides and methods of identification, synthesis, and use
AU773428B2 (en)	1998-10-13	2004-05-27	Peptide Biosciences, Inc.	Stabilized bioactive peptides and methods of identification, synthesis and use
US6967247B2 (en) *	2002-07-24	2005-11-22	Isis Pharmaceuticals, Inc.	Deprotection of phosphorus in oligonucleotide synthesis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH089639B2 (ja) *	1982-05-20	1996-01-31	サントリー株式会社	Ｃ末端アミド化ペプチドの前駆体およびその製造法

1983
- 1983-08-10 DE DE19833328793 patent/DE3328793A1/de not_active Withdrawn
1984
- 1984-08-04 DE DE8484109276T patent/DE3476681D1/de not_active Expired
- 1984-08-04 EP EP84109276A patent/EP0136472B1/de not_active Expired
- 1984-08-04 AT AT84109276T patent/ATE40717T1/de not_active IP Right Cessation
- 1984-08-08 US US06/638,789 patent/US4711847A/en not_active Expired - Fee Related
- 1984-08-08 GR GR80059A patent/GR80059B/el unknown
- 1984-08-09 DK DK383984A patent/DK383984A/da not_active Application Discontinuation
- 1984-08-09 JP JP59165761A patent/JPS6069098A/ja active Pending
- 1984-08-09 CA CA000460693A patent/CA1224167A/en not_active Expired

Also Published As

Publication number	Publication date
EP0136472A1 (de)	1985-04-10
DE3476681D1 (en)	1989-03-16
DE3328793A1 (de)	1985-02-28
DK383984D0 (da)	1984-08-09
CA1224167A (en)	1987-07-14
US4711847A (en)	1987-12-08
JPS6069098A (ja)	1985-04-19
GR80059B (en)	1984-12-12
ATE40717T1 (de)	1989-02-15
EP0136472B1 (de)	1989-02-08

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Legal Events

Date	Code	Title	Description
1991-04-22	AHB	Application shelved due to non-payment