DK3436074T3 - Thiazolidforbindelser til behandling af virale infektioner - Google Patents
Thiazolidforbindelser til behandling af virale infektioner Download PDFInfo
- Publication number
- DK3436074T3 DK3436074T3 DK17716741.8T DK17716741T DK3436074T3 DK 3436074 T3 DK3436074 T3 DK 3436074T3 DK 17716741 T DK17716741 T DK 17716741T DK 3436074 T3 DK3436074 T3 DK 3436074T3
- Authority
- DK
- Denmark
- Prior art keywords
- thiazolid
- compounds
- treatment
- viral infections
- infections
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662316463P | 2016-03-31 | 2016-03-31 | |
| PCT/US2017/024976 WO2017173056A1 (en) | 2016-03-31 | 2017-03-30 | Thiazolide compounds for treating viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3436074T3 true DK3436074T3 (da) | 2020-08-03 |
Family
ID=58530692
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17716741.8T DK3436074T3 (da) | 2016-03-31 | 2017-03-30 | Thiazolidforbindelser til behandling af virale infektioner |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US11135202B2 (da) |
| EP (2) | EP3436074B1 (da) |
| JP (2) | JP6567781B2 (da) |
| KR (3) | KR20210035339A (da) |
| CN (1) | CN108289961A (da) |
| AU (2) | AU2017244145B2 (da) |
| BR (1) | BR112018069974A2 (da) |
| CA (2) | CA3019326C (da) |
| CY (1) | CY1123221T1 (da) |
| DK (1) | DK3436074T3 (da) |
| EA (2) | EA202091849A1 (da) |
| ES (1) | ES2810303T3 (da) |
| HK (1) | HK1250945A1 (da) |
| HR (1) | HRP20201261T1 (da) |
| HU (1) | HUE050601T2 (da) |
| IL (2) | IL262018A (da) |
| LT (1) | LT3436074T (da) |
| MX (1) | MX2021004464A (da) |
| PH (1) | PH12018502058A1 (da) |
| PL (1) | PL3436074T3 (da) |
| PT (1) | PT3436074T (da) |
| SG (1) | SG11201808453UA (da) |
| SI (1) | SI3436074T1 (da) |
| UA (1) | UA126114C2 (da) |
| WO (1) | WO2017173056A1 (da) |
| ZA (1) | ZA201806644B (da) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111012778B (zh) * | 2018-10-10 | 2022-06-24 | 北京市农林科学院 | Nitazoxanide在抑制犬细小病毒中的应用 |
| CN109536460A (zh) * | 2018-12-07 | 2019-03-29 | 中国医学科学院医学生物学研究所 | 一种cv-a10病毒毒种及其人用灭活疫苗 |
| CN110787161B (zh) * | 2019-09-19 | 2022-09-27 | 中山大学 | 噻唑类化合物用于抗鱼类病毒的新用途 |
| CN111012788B (zh) * | 2019-12-12 | 2021-01-15 | 武汉职业技术学院 | 硝唑尼特和替唑尼特在制备抗猪繁殖与呼吸综合征病毒药物中的应用 |
| EP4182304A1 (en) | 2020-07-20 | 2023-05-24 | Romark Laboratories, L.C. | Crystalline salts of tizoxanide and 2-hydroxy-n-(5-chloro-1,3-thiazol-2-yl)benzamide (rm-4848) with ethanolamine, morpholine, propanolamine, piperazine and n-methylpiperazine |
| WO2022046622A1 (en) | 2020-08-24 | 2022-03-03 | Romark Laboratories L.C. | Use of thiazolides against coronaviruses |
| CA3219500A1 (en) * | 2021-05-28 | 2022-12-01 | Theodore HENDERSON | Treatment using an antiviral compound and nitazoxanide |
| WO2023040990A1 (zh) | 2021-09-15 | 2023-03-23 | 南京强新生物医药有限公司 | 治疗冠状病毒感染的新联用药物、药物组合物及其用途 |
| CN114404439B (zh) * | 2022-02-11 | 2023-07-11 | 山东农业大学 | 抑制不同类型猪繁殖与呼吸综合症病毒感染的阻断剂 |
| CN118161479A (zh) * | 2024-03-12 | 2024-06-11 | 中国动物卫生与流行病学中心 | 银杏双黄酮在制备抗猪塞内卡病毒的制剂中的应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1437800A (en) | 1973-08-08 | 1976-06-03 | Phavic Sprl | Derivatives of 2-benzamido-5-nitro-thiazoles |
| US5387598A (en) | 1994-04-13 | 1995-02-07 | Rossignol; Jean-Francois | Composition and galenic formulation suitable for combatting affections of the lower abdomen |
| US5859038A (en) | 1994-09-08 | 1999-01-12 | Romark Laboratories, L.C. | Method for treatment of helicobacter pylori infections |
| US5856348A (en) | 1994-09-08 | 1999-01-05 | Romark Laboratories, L.C. | Method for treatment of trematodes with pharmaceutical compositions of tizoxanide and nitazoxanide |
| MX9604483A (es) | 1994-09-08 | 1998-02-28 | Jean-Francois Rossignol | Derivados de benzamida, composiciones que contienen dicho derivado y uso de las mismas. |
| US5965590A (en) | 1994-09-08 | 1999-10-12 | Romark Lab Lc | Method for treatment of opportunistic infections with pharmaceutical compositions of tizoxanide and nitazoxanide |
| US5968961A (en) | 1997-05-07 | 1999-10-19 | Romark Laboratories, L.C. | Pharmaceutical compositions of tizoxanide and nitazoxanide |
| US5935591A (en) | 1998-01-15 | 1999-08-10 | Romark Laboratories, L.C. | Method for treatment of equine protozoal myeloencephalitis with thiazolides |
| US7582297B2 (en) | 2003-04-11 | 2009-09-01 | Medimmune, Llc | Methods of treating respiratory conditions |
| UA90864C2 (en) * | 2004-09-09 | 2010-06-10 | Ромарк Лебораториз, Л.К. | Halogenated benzamide derivatives |
| US20060194853A1 (en) | 2004-10-08 | 2006-08-31 | Rossignol Jean F | Alkyl benzamides |
| US20070015803A1 (en) * | 2005-04-12 | 2007-01-18 | Romark Laboratories L.C. | Methods for treating diseases through interruption of protein maturation, compounds that inhibit the function of molecular chaperones such as protein disulfide isomerases or interfere with glycosylation, pharmaceutical compositions comprising them, and screening methods for identifying therapeutic agents |
| CN101448497B (zh) | 2006-01-09 | 2013-07-10 | 罗马克实验室有限公司 | 包含硝唑尼特、替唑尼特、或其混合物的组合物在制备治疗丙型肝炎药物中的应用 |
| ES2550755T3 (es) | 2007-08-03 | 2015-11-12 | Romark Laboratories, L.C. | Compuestos de tiazolida sustituidos con alquilsulfonilo |
| GB0716292D0 (en) * | 2007-08-21 | 2007-09-26 | Biofocus Dpi Ltd | Imidazopyrazine compounds |
| EP2395840B1 (en) | 2009-02-13 | 2020-04-15 | Romark Laboratories, L.C. | Controlled release pharmaceutical formulations of nitazoxanide |
| AU2010247816B2 (en) * | 2009-05-12 | 2015-12-17 | Romark Laboratories L.C. | Haloalkyl heteroaryl benzamide compounds |
| AP2012006064A0 (en) | 2009-06-26 | 2012-02-29 | Romark Lab Lc | Compounds and methods for treating influenza. |
| WO2011160191A1 (en) * | 2010-06-25 | 2011-12-29 | Biota Scientific Management Pty Ltd | Compound for the treatment of enteroviruses |
| NZ611410A (en) | 2010-11-01 | 2016-02-26 | Romark Lab Lc | Alkylsulfinyl-substituted thiazolide compounds |
| CA2836253C (en) | 2011-05-16 | 2021-02-16 | Romark Laboratories, L.C. | Use of thiazolide compounds for the prevention and treatment of viral diseases, cancer and diseases caused by intracellular infections |
| WO2013136495A1 (ja) | 2012-03-15 | 2013-09-19 | トヨタ自動車株式会社 | 車両走行制御装置 |
| SG10201804835VA (en) * | 2013-10-11 | 2018-07-30 | Alios Biopharma Inc | Substituted nucleosides, nucleotides and analogs thereof |
| WO2016044656A1 (en) * | 2014-09-17 | 2016-03-24 | Ansun Biopharma, Inc. | Treatment of infection by human enterovirus d68 |
| EP3217795A4 (en) | 2014-11-11 | 2018-08-22 | Romark Laboratories, L.C. | Compositions and methods of treatment with prodrugs of tizoxanide, an analogue or salt thereof |
-
2017
- 2017-03-30 CN CN201780004281.XA patent/CN108289961A/zh active Pending
- 2017-03-30 US US15/474,267 patent/US11135202B2/en active Active
- 2017-03-30 EP EP17716741.8A patent/EP3436074B1/en active Active
- 2017-03-30 KR KR1020217008677A patent/KR20210035339A/ko not_active Application Discontinuation
- 2017-03-30 WO PCT/US2017/024976 patent/WO2017173056A1/en active Application Filing
- 2017-03-30 HU HUE17716741A patent/HUE050601T2/hu unknown
- 2017-03-30 PT PT177167418T patent/PT3436074T/pt unknown
- 2017-03-30 EA EA202091849A patent/EA202091849A1/ru unknown
- 2017-03-30 CA CA3019326A patent/CA3019326C/en active Active
- 2017-03-30 ES ES17716741T patent/ES2810303T3/es active Active
- 2017-03-30 AU AU2017244145A patent/AU2017244145B2/en not_active Ceased
- 2017-03-30 SG SG11201808453UA patent/SG11201808453UA/en unknown
- 2017-03-30 EA EA201891975A patent/EA036505B1/ru unknown
- 2017-03-30 KR KR1020187030535A patent/KR102233826B1/ko active IP Right Grant
- 2017-03-30 DK DK17716741.8T patent/DK3436074T3/da active
- 2017-03-30 KR KR1020187030521A patent/KR102136803B1/ko active IP Right Grant
- 2017-03-30 PL PL17716741T patent/PL3436074T3/pl unknown
- 2017-03-30 BR BR112018069974A patent/BR112018069974A2/pt not_active Application Discontinuation
- 2017-03-30 UA UAA201809863A patent/UA126114C2/uk unknown
- 2017-03-30 JP JP2018550728A patent/JP6567781B2/ja active Active
- 2017-03-30 CA CA3113354A patent/CA3113354A1/en not_active Abandoned
- 2017-03-30 SI SI201730344T patent/SI3436074T1/sl unknown
- 2017-03-30 LT LTEP17716741.8T patent/LT3436074T/lt unknown
- 2017-03-30 EP EP20157908.3A patent/EP3677282A1/en not_active Withdrawn
-
2018
- 2018-08-14 HK HK18110444.1A patent/HK1250945A1/zh unknown
- 2018-09-26 PH PH12018502058A patent/PH12018502058A1/en unknown
- 2018-09-27 IL IL262018A patent/IL262018A/en unknown
- 2018-09-28 MX MX2021004464A patent/MX2021004464A/es unknown
- 2018-10-05 ZA ZA2018/06644A patent/ZA201806644B/en unknown
-
2019
- 2019-07-31 JP JP2019141433A patent/JP2019203014A/ja active Pending
- 2019-09-23 AU AU2019236602A patent/AU2019236602A1/en not_active Abandoned
-
2020
- 2020-08-06 CY CY20201100732T patent/CY1123221T1/el unknown
- 2020-08-11 HR HRP20201261TT patent/HRP20201261T1/hr unknown
-
2021
- 2021-01-21 IL IL280327A patent/IL280327A/en unknown
- 2021-10-01 US US17/491,878 patent/US20220125767A1/en active Pending
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