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DK32190A - INTERMEDIATE FOR THE PREPARATION OF CHOLESTEROL SYNTHESIS INHIBITORS AND PROCEDURE FOR THE PRODUCTION OF THE INTERMEDIATE - Google Patents

INTERMEDIATE FOR THE PREPARATION OF CHOLESTEROL SYNTHESIS INHIBITORS AND PROCEDURE FOR THE PRODUCTION OF THE INTERMEDIATE Download PDF

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Publication number
DK32190A
DK32190A DK032190A DK32190A DK32190A DK 32190 A DK32190 A DK 32190A DK 032190 A DK032190 A DK 032190A DK 32190 A DK32190 A DK 32190A DK 32190 A DK32190 A DK 32190A
Authority
DK
Denmark
Prior art keywords
procedure
preparation
production
synthesis inhibitors
cholesterol synthesis
Prior art date
Application number
DK032190A
Other languages
Danish (da)
Other versions
DK32190D0 (en
DK167805B1 (en
Inventor
Aiya Sato
Akira Terahara
Yoshio Tsujita
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=12604367&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK32190(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of DK32190A publication Critical patent/DK32190A/en
Publication of DK32190D0 publication Critical patent/DK32190D0/en
Application granted granted Critical
Publication of DK167805B1 publication Critical patent/DK167805B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK032190A 1980-03-31 1990-02-07 INTERMEDIATE FOR THE PREPARATION OF CHOLESTEROL SYNTHESIS INHIBITORS DK167805B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP55041292A JPH0692381B2 (en) 1980-03-31 1980-03-31 MB-530A derivative
JP4129280 1980-03-31

Publications (3)

Publication Number Publication Date
DK32190A true DK32190A (en) 1990-02-07
DK32190D0 DK32190D0 (en) 1990-02-07
DK167805B1 DK167805B1 (en) 1993-12-20

Family

ID=12604367

Family Applications (3)

Application Number Title Priority Date Filing Date
DK145481A DK151273C (en) 1980-03-31 1981-03-31 PROCEDURE FOR THE PREPARATION OF THE CHOLESTEROL BIOSYNTHESE INHIBITOR MB-530A.
DK032190A DK167805B1 (en) 1980-03-31 1990-02-07 INTERMEDIATE FOR THE PREPARATION OF CHOLESTEROL SYNTHESIS INHIBITORS
DK032290A DK32290A (en) 1980-03-31 1990-02-07 APPLICATION OF 8'-ACYLED DERIVATIVES OF THE INTERMEDIATE COMPOUND MB-530A FOR THE PREPARATION OF A MEDICINE FOR TREATING HYPERCHOLESTEROLAEMIA

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK145481A DK151273C (en) 1980-03-31 1981-03-31 PROCEDURE FOR THE PREPARATION OF THE CHOLESTEROL BIOSYNTHESE INHIBITOR MB-530A.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK032290A DK32290A (en) 1980-03-31 1990-02-07 APPLICATION OF 8'-ACYLED DERIVATIVES OF THE INTERMEDIATE COMPOUND MB-530A FOR THE PREPARATION OF A MEDICINE FOR TREATING HYPERCHOLESTEROLAEMIA

Country Status (15)

Country Link
JP (1) JPH0692381B2 (en)
AT (1) ATA150781A (en)
AU (1) AU6893281A (en)
BE (1) BE888214A (en)
CH (1) CH646966A5 (en)
DE (2) DE3153666C2 (en)
DK (3) DK151273C (en)
FI (1) FI810991L (en)
FR (1) FR2479222A1 (en)
GB (1) GB2073193A (en)
IE (1) IE52367B1 (en)
IT (1) IT1144325B (en)
MX (1) MX9203567A (en)
NL (1) NL8101592A (en)
SE (1) SE461590B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472426A (en) * 1982-12-22 1984-09-18 Merck & Co., Inc. Antihypercholesterolemic compounds
ATE69602T1 (en) * 1985-09-13 1991-12-15 Sankyo Co HYDROXY-ML-236B DERIVATIVES, THEIR PREPARATION AND USE.
US4997848A (en) * 1987-10-27 1991-03-05 Sankyo Company, Limited Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
US5075327A (en) * 1988-08-10 1991-12-24 Hoffmann-La Roche Inc. Antipsoriatic agents
US5021451A (en) * 1988-11-14 1991-06-04 Hoffman-La Roche Inc. Method for inhibiting hyperproliferative diseases
US5200549A (en) * 1988-11-14 1993-04-06 Hoffman-La Roche Inc. Antipsoriatic agents
US5073568A (en) * 1988-11-14 1991-12-17 Hoffmann-La Roche Inc. Antipsoriatic agents
US5159104A (en) * 1991-05-01 1992-10-27 Merck & Co., Inc. Process to simvastatin ester
FR2937537A1 (en) * 2008-10-29 2010-04-30 Centre Nat Rech Scient NANOPARTICLES OF STATIN
KR101820099B1 (en) 2013-01-18 2018-01-18 에스프린팅솔루션 주식회사 resistive heat generating material, heating member and fusing device adopting the same
EP3737676B1 (en) 2018-01-09 2024-03-06 Ligand Pharmaceuticals, Inc. Acetal compounds and therapeutic uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5612114B2 (en) * 1974-06-07 1981-03-18
JPS5925599B2 (en) * 1979-02-20 1984-06-19 三共株式会社 New physiologically active substance monacolin K and its production method
GR69216B (en) * 1979-06-15 1982-05-07 Merck & Co Inc
US4231938A (en) * 1979-06-15 1980-11-04 Merck & Co., Inc. Hypocholesteremic fermentation products and process of preparation
AU548996B2 (en) * 1980-02-04 1986-01-09 Merck & Co., Inc. Tetrahydro-2h-pyran-2-one derivatives
PT72394B (en) * 1980-02-04 1982-09-06 Merck & Co Inc Process for preparing dihydro and tetrahydromevinoline hypocholesterolimics
ZA81703B (en) * 1980-02-04 1982-09-29 Merck & Co Inc New antihypercholesterolemic compounds,intermediates and processes
US4282155A (en) * 1980-02-04 1981-08-04 Merck & Co., Inc. Antihypercholesterolemic compounds

Also Published As

Publication number Publication date
NL8101592A (en) 1981-10-16
SE461590B (en) 1990-03-05
DK32290D0 (en) 1990-02-07
JPS56138181A (en) 1981-10-28
IE52367B1 (en) 1987-09-30
DE3112566C2 (en) 1990-04-05
SE8102047L (en) 1981-10-01
AU6893281A (en) 1981-10-08
JPH0692381B2 (en) 1994-11-16
GB2073193A (en) 1981-10-14
DE3112566A1 (en) 1982-03-11
IT1144325B (en) 1986-10-29
IT8167438A0 (en) 1981-03-30
IE810698L (en) 1981-09-30
DK151273C (en) 1988-07-04
DE3153666C2 (en) 1993-11-11
BE888214A (en) 1981-09-30
FI810991L (en) 1981-10-01
DK32290A (en) 1990-02-07
DK151273B (en) 1987-11-16
DK32190D0 (en) 1990-02-07
MX9203567A (en) 1992-09-01
DK145481A (en) 1981-10-01
FR2479222B1 (en) 1983-08-26
DK167805B1 (en) 1993-12-20
ATA150781A (en) 1983-03-15
FR2479222A1 (en) 1981-10-02
CH646966A5 (en) 1984-12-28

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired