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DK3290024T3 - Vedvarende indgivelse af aktive midler til behandling af glaukom og okulær hypertension - Google Patents

Vedvarende indgivelse af aktive midler til behandling af glaukom og okulær hypertension Download PDF

Info

Publication number
DK3290024T3
DK3290024T3 DK17183171.2T DK17183171T DK3290024T3 DK 3290024 T3 DK3290024 T3 DK 3290024T3 DK 17183171 T DK17183171 T DK 17183171T DK 3290024 T3 DK3290024 T3 DK 3290024T3
Authority
DK
Denmark
Prior art keywords
glaucum
submission
continuing
treatment
ocular hypertension
Prior art date
Application number
DK17183171.2T
Other languages
English (en)
Inventor
Suzanne Cadden
Yong Hao
Deepank Utkhede
Valery Rubinchik
Charles Richard Kjellbotn
Original Assignee
Mati Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mati Therapeutics Inc filed Critical Mati Therapeutics Inc
Application granted granted Critical
Publication of DK3290024T3 publication Critical patent/DK3290024T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00772—Apparatus for restoration of tear ducts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts, ocular implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK17183171.2T 2011-08-29 2012-08-29 Vedvarende indgivelse af aktive midler til behandling af glaukom og okulær hypertension DK3290024T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161528736P 2011-08-29 2011-08-29
US201261644397P 2012-05-08 2012-05-08
EP16187646.1A EP3120834A1 (en) 2011-08-29 2012-08-29 Sustained release delivery of active agents to treat glaucoma and ocular hypertension

Publications (1)

Publication Number Publication Date
DK3290024T3 true DK3290024T3 (da) 2019-06-03

Family

ID=47744708

Family Applications (2)

Application Number Title Priority Date Filing Date
DK12827871.0T DK2750660T3 (da) 2011-08-29 2012-08-29 Indgivelse med langvarig frigørelse af aktive midler til behandling af glaukom og okulær hypertension
DK17183171.2T DK3290024T3 (da) 2011-08-29 2012-08-29 Vedvarende indgivelse af aktive midler til behandling af glaukom og okulær hypertension

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK12827871.0T DK2750660T3 (da) 2011-08-29 2012-08-29 Indgivelse med langvarig frigørelse af aktive midler til behandling af glaukom og okulær hypertension

Country Status (8)

Country Link
US (4) US20130053794A1 (da)
EP (3) EP3290024B1 (da)
JP (1) JP6100782B2 (da)
CN (2) CN103889401B (da)
CA (1) CA2846384C (da)
DK (2) DK2750660T3 (da)
ES (2) ES2611807T3 (da)
WO (1) WO2013030679A2 (da)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136010A (en) 1999-03-04 2000-10-24 Perclose, Inc. Articulating suturing device and method
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
AU2010246067B2 (en) 2009-05-04 2016-07-07 Eyepoint Pharmaceuticals Us, Inc. Porous silicon drug-eluting particles
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
US10272040B2 (en) 2010-08-12 2019-04-30 Nanyang Technological University Liposomal formulation for ocular drug delivery
CA2816576C (en) 2010-11-01 2020-06-02 Psivida Us, Inc. Bioerodible silicon-based devices for delivery of therapeutic agents
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
JP6100782B2 (ja) * 2011-08-29 2017-03-22 キューエルティー インコーポレイテッド 緑内障および高眼圧症を治療するための活性剤の徐放送達
US20140309610A1 (en) * 2013-03-12 2014-10-16 Psivida Corp. Drug Delivery Device Comprising Silicon-Based Carrier Particles
JP2016512839A (ja) 2013-03-15 2016-05-09 シヴィダ・ユーエス・インコーポレイテッドＰｓｉｖｉｄａ Ｕｓ， Ｉｎｃ． 治療物質の送達のための生体内分解性ケイ素系組成物
CA2930390A1 (en) * 2013-11-15 2015-05-21 Glaukos Corporation Ocular implants configured to store and release stable drug formulations
US9956195B2 (en) 2014-01-07 2018-05-01 Nanyang Technological University Stable liposomal formulations for ocular drug delivery
WO2015184173A1 (en) 2014-05-29 2015-12-03 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
CN107206015A (zh) 2014-10-24 2017-09-26 阿维塔斯有限公司 透细胞质膜的传递
KR102511830B1 (ko) * 2014-11-25 2023-03-17 엑시모어 엘티디. 단일 및 다수 생체활성제를 전달하기 위한 조성물 및 방법
WO2016099946A1 (en) * 2014-12-17 2016-06-23 Paul Gavaris Canalicular plug, method and kit for treating dry eye
US10219943B2 (en) * 2015-06-26 2019-03-05 Innfocus, Inc. Glaucoma device delivery system and trans-conjunctival method of delivery
CA2993182A1 (en) * 2015-07-22 2017-01-26 Incept, Llc Coated punctal plug
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
WO2017053885A1 (en) * 2015-09-25 2017-03-30 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
US11013403B2 (en) 2015-09-29 2021-05-25 The Regents Of The University Of California Methods of diagnosing diseases of mucosal surfaces
CN116676292A (zh) 2015-12-30 2023-09-01 阿维塔斯有限公司 基因编辑蛋白和组合物向细胞和组织的无载体递送
CN109937025B (zh) 2016-04-20 2022-07-29 多斯医学公司 生物可吸收眼部药物的递送装置
US20200078215A1 (en) * 2016-07-06 2020-03-12 MicroOptx Inc. Glaucoma treatment devices and methods
EP3474794A4 (en) * 2016-07-13 2019-07-24 Mati Therapeutics Inc. STATIC PIN INTRODUCTION TOOL FOR LACRYMAL IMPLANT
KR20200069261A (ko) * 2017-05-30 2020-06-16 엑시모어 엘티디. 항생제 마크로라이드를 전달하는 안구건조증을 치료하기 위한 조성물 및 방법
CN108433748A (zh) * 2018-04-11 2018-08-24 中山大学中山眼科中心 带阀门的液态标本的采集装置
JP2023510747A (ja) * 2020-01-08 2023-03-15 アイポイント ファーマシューティカルズ， インコーポレイテッド Ｔｉｅ－２活性化物質とプロスタグランジンの組み合わせおよびその使用
CN111920577B (zh) * 2020-06-03 2022-07-15 永康市第一人民医院 泪道瓣膜探通扩张器械
CN111920578B (zh) * 2020-06-03 2022-08-02 永康市第一人民医院 一种泪道检查治疗器械
CN112618152B (zh) * 2020-12-14 2022-02-08 中国人民解放军总医院 一种可测眼压的粘弹剂及灌注液一体推注装置

Family Cites Families (205)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3321108A (en) 1965-11-26 1967-05-23 William E Bowe Printing ink dispenser
US3681608A (en) 1971-03-17 1972-08-01 Us Navy Laser beam receiver having a high signal to noise ratio
US3865108A (en) 1971-05-17 1975-02-11 Ortho Pharma Corp Expandable drug delivery device
US3949750A (en) 1974-10-07 1976-04-13 Freeman Jerre M Punctum plug and method for treating keratoconjunctivitis sicca (dry eye) and other ophthalmic aliments using same
US4014335A (en) 1975-04-21 1977-03-29 Alza Corporation Ocular drug delivery device
US4281654A (en) 1980-04-07 1981-08-04 Alza Corporation Drug delivery system for controlled ocular therapy
US4304765A (en) 1980-10-14 1981-12-08 Alza Corporation Ocular insert housing steroid in two different therapeutic forms
NZ200429A (en) 1981-04-30 1984-10-19 Smith & Nephew Ass Applicator for placing pharmaceutically active agent in contact with moist surface,e.g.,eye
US4660546A (en) 1984-11-07 1987-04-28 Robert S. Herrick Method for treating for deficiency of tears
US5049142A (en) 1984-11-07 1991-09-17 Herrick Robert S Intracanalicular implant for horizontal canalicular blockade treatment of the eye
US5053030A (en) 1984-11-07 1991-10-01 Herrick Robert S Intracanalicular implant for horizontal canalicular blockade treatment of the eye
US5229128A (en) 1986-06-11 1993-07-20 Haddad Heskel M Drug delivery ophthalmic insert and method of preparing same
US5322691A (en) 1986-10-02 1994-06-21 Sohrab Darougar Ocular insert with anchoring protrusions
US4747404A (en) 1986-11-10 1988-05-31 Kresge Eye Institute Of Wayne State University Foldable intraocular lens inserter
US4952581A (en) 1987-04-03 1990-08-28 The Trustees Of Columbia University In The City Of New York Use of a prostaglandin in combination with an adrenergic blocking agent for reduction of intraocular pressure
US4933708A (en) 1987-04-06 1990-06-12 Brother Kogyo Kabushiki Kaisha Image recording apparatus using microcapsules to form a color image
US4886488A (en) 1987-08-06 1989-12-12 White Thomas C Glaucoma drainage the lacrimal system and method
GB8806367D0 (en) 1988-03-17 1988-04-13 Erba Carlo Spa Siloxane matrices with internal non-uniform drug distribution
US4936008A (en) 1988-05-09 1990-06-26 Teledyne Mec Laser striping method for assembling TWT
US4934708A (en) 1988-05-20 1990-06-19 Kolkind Gerald L Family quiz board game
US4915684A (en) 1988-06-21 1990-04-10 Mackeen Donald L Method and apparatus for modulating the flow of lacrimal fluid through a punctum and associated canaliculus
US5296504A (en) 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US5133159A (en) 1989-01-13 1992-07-28 Nestle S.A. Method for polishing silicone products
US4959048A (en) 1989-01-17 1990-09-25 Helix Medical, Inc. Lacrimal duct occluder
US5128058A (en) 1989-05-31 1992-07-07 Hoya Corporation Contact lens cleaner containing a microcapsular polishing agent
US4931708A (en) 1989-10-05 1990-06-05 Thore Johnsen Independent band spring door gear motor operator
IE910450A1 (en) 1990-02-15 1991-08-28 Bausch & Lomb Soft contact lens processing aid
JP2605918B2 (ja) 1990-03-27 1997-04-30 日産自動車株式会社 車両の旋回挙動制御装置
US5171270A (en) 1990-03-29 1992-12-15 Herrick Robert S Canalicular implant having a collapsible flared section and method
US5163959A (en) 1990-03-29 1992-11-17 Herrick Robert S Method for treating an eye with a canalicular implant having a collapsible flared section
US5041081A (en) 1990-05-18 1991-08-20 Odrich Ronald B Ocular implant for controlling glaucoma
US5090108A (en) 1990-10-17 1992-02-25 Globe Products Inc. Stator coil winding and lead termination method and apparatus
US5273530A (en) 1990-11-14 1993-12-28 The University Of Rochester Intraretinal delivery and withdrawal instruments
JP3300391B2 (ja) 1991-10-11 2002-07-08 株式会社東芝 画像処理装置
NZ245514A (en) 1991-12-27 1994-12-22 Merck & Co Inc Controlled release drug delivery device comprising a core and a polymeric coating which is water impermeable but contains apertures to expose the core
US5283063A (en) 1992-01-31 1994-02-01 Eagle Vision Punctum plug method and apparatus
US5334137A (en) 1992-02-21 1994-08-02 Eagle Vision, Inc. Lacrimal fluid control device
US5211308A (en) 1992-02-27 1993-05-18 Nyco International, Inc. Universal funnel for a paper dispenser
US5254089A (en) 1992-04-02 1993-10-19 Boston Scientific Corp. Medication dispensing balloon catheter
US5259508A (en) 1992-08-27 1993-11-09 Beckerman Stephen M Protective shipping package
US5469867A (en) 1992-09-02 1995-11-28 Landec Corporation Cast-in place thermoplastic channel occluder
US5318513A (en) 1992-09-24 1994-06-07 Leib Martin L Canalicular balloon fixation stent
CA2146127C (en) 1992-10-13 2000-06-13 Louis Desantis, Jr. Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
FR2700265B1 (fr) 1993-01-08 1995-03-31 France Chirurgie Instr Bouchon méatique pour pathologie lacrymale.
US5707643A (en) 1993-02-26 1998-01-13 Santen Pharmaceutical Co., Ltd. Biodegradable scleral plug
US5417651A (en) 1993-07-01 1995-05-23 Guena; Nicolas Punctum plug and monocanalicular probe for lacrimal pathology
WO1995003807A1 (en) 1993-07-27 1995-02-09 The University Of Sydney Treatment of age-related macular degeneration
US5423777A (en) 1993-10-27 1995-06-13 Tajiri; Akira Punctum plug
US5466233A (en) 1994-04-25 1995-11-14 Escalon Ophthalmics, Inc. Tack for intraocular drug delivery and method for inserting and removing same
JP3486758B2 (ja) 1994-06-24 2004-01-13 株式会社高研 注入可能な涙小管閉鎖剤
EP0957949B1 (en) 1995-05-14 2004-08-04 Optonol Ltd. Intraocular implant, delivery device, and method of implantation
US5723005A (en) 1995-06-07 1998-03-03 Herrick Family Limited Partnership Punctum plug having a collapsible flared section and method
US6149684A (en) 1995-06-07 2000-11-21 Herrick; Robert S. Punctum plug having a thin elongated lip and a distal starting tip and method of using
US5766243A (en) 1995-08-21 1998-06-16 Oasis Medical, Inc. Abrasive polished canalicular implant
US5773019A (en) 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5741292A (en) 1995-10-26 1998-04-21 Eagle Vision Punctum dilating and plug inserting instrument with push-button plug release
US5824073A (en) 1996-03-18 1998-10-20 Peyman; Gholam A. Macular indentor for use in the treatment of subretinal neovascular membranes
JPH1033584A (ja) 1996-07-26 1998-02-10 M L C:Kk 涙道挿管器具
US5928662A (en) 1996-07-31 1999-07-27 Phillips; Andrew F. Ocular drug delivery device
US5993407A (en) 1996-10-25 1999-11-30 Moazed; Kambiz Thomas Transnasal lacrimal insert
JP2001504042A (ja) 1996-11-01 2001-03-27 アルコン ラボラトリーズ，インコーポレイテッド 軟質アクリル物品の低温研磨方法
EP0944371A1 (fr) 1997-02-04 1999-09-29 Alain Fouere Tampon meatique vissable pour canal lacrymal
US6082362A (en) 1997-03-27 2000-07-04 Eagle Vision, Inc. Punctum plug
US6016806A (en) 1997-03-27 2000-01-25 Eaglevision, Inc Punctum plug
US6041785A (en) 1997-03-27 2000-03-28 Eaglevision, Inc. Punctum plug
US6027470A (en) 1998-06-10 2000-02-22 Eagle Vision, Inc. Punctum plug and method for inserting the same into the punctual opening
DK0981327T3 (da) 1997-05-07 2003-03-10 Galen Chemicals Ltd Intravaginale lægemiddeltilførselsanordninger til indgivelse af testosteron og testosteronprecursorer
US5961370A (en) 1997-05-08 1999-10-05 Chiron Vision Corporation Intraocular lens tumbling process using coated beads
MY125870A (en) 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
US6306426B1 (en) 1997-08-11 2001-10-23 Allergan Sales, Inc. Implant device with a retinoid for improved biocompatibility
US5830171A (en) * 1997-08-12 1998-11-03 Odyssey Medical, Inc. Punctal occluder
US5902598A (en) 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US6060439A (en) 1997-09-29 2000-05-09 Kyzen Corporation Cleaning compositions and methods for cleaning resin and polymeric materials used in manufacture
US6335335B2 (en) 1997-11-05 2002-01-01 Senju Pharmaceutical Co., Ltd. Prolonged-action eye drop
US5947974A (en) 1997-12-09 1999-09-07 Allergan Folding device and method for an intraocular lens
NL1008090C2 (nl) 1998-01-22 1999-07-26 Lubberman Bernardus H M Plug voor het afsluiten van een traanbuis.
WO1999044553A1 (en) 1998-03-02 1999-09-10 Herrick Family Limited Partnership A punctum plug having a collapsible flared section and method
US6290684B1 (en) 1998-03-02 2001-09-18 Herrick Family Limited Partnership Punctum plug having a collapsible expanded section and distal tip extending substantially perpendicular thereto and method of inserting same
US6196993B1 (en) 1998-04-20 2001-03-06 Eyelab Group, Llc Ophthalmic insert and method for sustained release of medication to the eye
US6306114B1 (en) * 1998-06-16 2001-10-23 Eagle Vision, Inc. Valved canalicular plug for lacrimal duct occlusion
US6225348B1 (en) 1998-08-20 2001-05-01 Alfred W. Paulsen Method of treating macular degeneration with a prostaglandin derivative
JP2000070296A (ja) 1998-08-27 2000-03-07 M L C:Kk 涙道内挿管器具
US6095901A (en) 1998-12-09 2000-08-01 Alcon Laboratories, Inc. Polishing method for soft acrylic articles
US20040121014A1 (en) 1999-03-22 2004-06-24 Control Delivery Systems, Inc. Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US6622308B1 (en) 1999-03-23 2003-09-16 Scientific-Atlanta, Inc. Automatic digital television (DTV) bypass for a CATV converter using a CATV tuner
US6234175B1 (en) 1999-03-23 2001-05-22 Medennium, Inc. Smart ocular plug design and method of insertion for punctal and intracanalicular implants
US6383192B1 (en) 1999-04-28 2002-05-07 Mlc Limited Company Apparatus for intubation of lacrimal duct
US6428502B1 (en) 1999-06-25 2002-08-06 Alcon Manufacturing, Ltd. Punctal cannula
US6706275B1 (en) 1999-09-08 2004-03-16 Matthew W. Camp Scleral plug system
US6331313B1 (en) 1999-10-22 2001-12-18 Oculex Pharmaceticals, Inc. Controlled-release biocompatible ocular drug delivery implant devices and methods
US6264971B1 (en) 1999-11-04 2001-07-24 Btg International Limited Ocular insert
US6566345B2 (en) 2000-04-28 2003-05-20 Fziomed, Inc. Polyacid/polyalkylene oxide foams and gels and methods for their delivery
AU2626601A (en) 2000-01-03 2001-07-16 Johns Hopkins University, The Device and method for manual retinal vein catheterization
US6344047B1 (en) 2000-02-02 2002-02-05 Eagle Vision Instrument for inserting a punctum plug and method for manufacturing the instrument
US7867186B2 (en) 2002-04-08 2011-01-11 Glaukos Corporation Devices and methods for treatment of ocular disorders
US6638239B1 (en) 2000-04-14 2003-10-28 Glaukos Corporation Apparatus and method for treating glaucoma
US7708711B2 (en) 2000-04-14 2010-05-04 Glaukos Corporation Ocular implant with therapeutic agents and methods thereof
US20040175410A1 (en) 2000-04-26 2004-09-09 Control Delivery Systems, Inc. Sustained release device and method for ocular delivery of carbonic anhydrase inhibitors
US20040208910A1 (en) 2000-04-26 2004-10-21 Control Delivery Systems, Inc. Sustained release device and method for ocular delivery of adrenergic agents
US6375972B1 (en) 2000-04-26 2002-04-23 Control Delivery Systems, Inc. Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof
US6371122B1 (en) 2000-06-20 2002-04-16 Robert M. Mandelkorn Gauge/dilator apparatus
US6629533B1 (en) 2000-06-30 2003-10-07 Eagle Vision, Inc. Punctum plug with at least one anchoring arm
ES2231306T3 (es) 2000-08-04 2005-05-16 Medennium, Inc. Tapon ocular para implantar en el punto lagrimal y el canaliculo.
US6534693B2 (en) 2000-11-06 2003-03-18 Afmedica, Inc. Surgically implanted devices having reduced scar tissue formation
US6756049B2 (en) 2000-12-29 2004-06-29 Bausch & Lomb Incorporated Sustained release drug delivery devices
JP2004521882A (ja) 2001-01-03 2004-07-22 ボシュ・アンド・ロム・インコーポレイテッド 組立式透過性プラグを備えた徐放薬剤送達装置
US6991808B2 (en) 2001-01-26 2006-01-31 Bausch & Lomb Inc. Process for the production of sustained release drug delivery devices
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
DE60225815T2 (de) 2001-04-07 2009-02-05 Glaukos Corp., Laguna Hills Glaukom-stent für die glaukom-behandlung
US6981958B1 (en) 2001-05-02 2006-01-03 Glaukos Corporation Implant with pressure sensor for glaucoma treatment
US6605108B2 (en) 2001-04-13 2003-08-12 Eagle Vision, Inc. Monocanalicular stent
US6982090B2 (en) 2001-05-10 2006-01-03 Gillespie Donald E More easily visualized punctum plug configurations
US7404825B2 (en) 2001-06-11 2008-07-29 Herrick Ii Robert S Implant capable of forming a differential image in an eye
FR2829019B3 (fr) 2001-08-31 2003-10-31 Alain Fouere Bouchons lacrymaux et methodes de mise en place de ces dispositifs
NZ530550A (en) 2001-09-11 2004-11-26 Smart Drug Systems Inc Preparation of sustained release pharmaceutical composition
US6729939B2 (en) 2001-12-17 2004-05-04 Bausch & Lomb Incorporated Polishing method for intraocular lens
FR2834446B1 (fr) 2002-01-08 2004-02-13 Ioltechnologie Production Clou meatique a expansion
US20050255564A1 (en) 2002-01-18 2005-11-17 Takara Bio Inc Sulfated fucan
US7204995B2 (en) 2002-01-31 2007-04-17 El-Sherif Dalia M Treatment and control of dry eye by use of biodegradable polymer capsules
US20040116524A1 (en) 2002-02-04 2004-06-17 Cohen Ben Z. Method of administering opthalmic fluids
US9301875B2 (en) 2002-04-08 2016-04-05 Glaukos Corporation Ocular disorder treatment implants with multiple opening
US20040147870A1 (en) 2002-04-08 2004-07-29 Burns Thomas W. Glaucoma treatment kit
US8871241B2 (en) 2002-05-07 2014-10-28 Psivida Us, Inc. Injectable sustained release delivery devices
US7300364B2 (en) 2004-02-06 2007-11-27 Acushnet Company Multi-layer golf ball having velocity gradient from faster center to slower cover
US20040043067A1 (en) 2002-06-19 2004-03-04 Salamone Joseph C. Fluorosiloxane matrix controlled diffusion drug delivery systems
US6866563B2 (en) 2002-06-27 2005-03-15 Bausch & Lomb Incorporated Apparatus and method for target polishing intraocular lenses
FR2841770B1 (fr) 2002-07-05 2004-10-01 Ioltechnologie Production Clou meatique d'obturation d'un meat lacrymal
FR2844182B1 (fr) 2002-09-11 2004-12-03 Humanoptics Ag Bouchon d'obturation d'un canalicule lacrymal
US7169163B2 (en) 2002-09-30 2007-01-30 Bruce Becker Transnasal method and catheter for lacrimal system
JP2004119919A (ja) 2002-09-30 2004-04-15 Hitachi Ltd 半導体薄膜および半導体薄膜の製造方法
US7785578B2 (en) 2002-10-11 2010-08-31 Aciont, Inc. Non-invasive ocular drug delivery
US7354574B2 (en) 2002-11-07 2008-04-08 Advanced Ocular Systems Limited Treatment of ocular disease
WO2004058289A1 (en) 2002-12-20 2004-07-15 Chakshu Research, Inc. Ophthalmic formulation for the prevention and treatment of ocular conditions
US20040144392A1 (en) 2003-01-23 2004-07-29 Mueller Richard L. Breast nipple duct protective device
WO2004075781A2 (en) 2003-02-26 2004-09-10 Medivas, Llc Bioactive stents and methods for use thereof
US20050283109A1 (en) 2003-03-07 2005-12-22 Peyman Gholam A Method and apparatus for lacrimal canal obstruction
JP2004321669A (ja) * 2003-04-28 2004-11-18 Masao Miyake 涙道閉塞治療用具
WO2004098565A2 (en) 2003-05-02 2004-11-18 Surmodics, Inc. Implantable controlled release bioactive agent delivery device
US7017580B2 (en) 2003-05-22 2006-03-28 Clarity Corporation Punctum plug system including a punctum plug and passive insertion tool therefor
US7204253B2 (en) 2003-05-22 2007-04-17 Clarity Corporation Punctum plug
US20040236343A1 (en) 2003-05-23 2004-11-25 Taylor Jon B. Insertion tool for ocular implant and method for using same
JP4104137B2 (ja) 2003-05-30 2008-06-18 有限会社エム・エル・シー 涙点プラグ
US7662864B2 (en) 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
JP4339635B2 (ja) 2003-06-12 2009-10-07 有限会社エム・エル・シー 涙点プラグ
US6994684B2 (en) * 2003-06-16 2006-02-07 Alphamed Inc. Punctum plugs having fluid collecting recesses and methods of punctal occlusion
US20040265356A1 (en) 2003-06-30 2004-12-30 Bausch & Lomb Incorporated Drug delivery device
JP4280128B2 (ja) 2003-08-19 2009-06-17 有限会社エム・エル・シー 涙点プラグ
JP2005110765A (ja) 2003-10-03 2005-04-28 M L C:Kk 涙点プラグセット
JP2005110930A (ja) 2003-10-07 2005-04-28 M L C:Kk 涙点プラグセット
US20050129731A1 (en) 2003-11-03 2005-06-16 Roland Horres Biocompatible, biostable coating of medical surfaces
US20050095269A1 (en) 2003-11-04 2005-05-05 Ainpour Parviz R. Gel plug for blockage of the canaliculus
NZ575950A (en) 2003-11-13 2010-06-25 Psivida Inc Injectable sustained release implant having a bioerodible matrix core and a bioerodible skin
US7291125B2 (en) 2003-11-14 2007-11-06 Transcend Medical, Inc. Ocular pressure regulation
SI1704141T1 (sl) 2004-01-05 2016-04-29 Nicox S.A. Nitrooksi-derivati prostaglandinov
US20050220882A1 (en) 2004-03-04 2005-10-06 Wilson Pritchard Materials for medical implants and occlusive devices
US20050197614A1 (en) 2004-03-04 2005-09-08 Wilson Pritchard Occlusive biomedical devices, punctum plugs, and methods of use thereof
US20050232972A1 (en) * 2004-04-15 2005-10-20 Steven Odrich Drug delivery via punctal plug
JP2004202276A (ja) 2004-04-16 2004-07-22 M L C:Kk 涙道再建用挿管器具
US20050244469A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Extended therapeutic effect ocular implant treatments
JP2005312835A (ja) 2004-04-30 2005-11-10 M L C:Kk 糸で補強した涙道ステント
US8425929B2 (en) 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
JP4644438B2 (ja) 2004-05-11 2011-03-02 有限会社エム・エル・シー ツバつき涙道ステント
JP4510511B2 (ja) 2004-05-18 2010-07-28 有限会社エム・エル・シー ツバを円盤で補強した涙道ステント及び涙道プラグ
EP1765454B1 (en) 2004-07-02 2016-04-13 Mati Therapeutics Inc. Treatment medium delivery device for the eye
US20060020253A1 (en) 2004-07-26 2006-01-26 Prescott Anthony D Implantable device having reservoir with controlled release of medication and method of manufacturing the same
US7117870B2 (en) 2004-07-26 2006-10-10 Clarity Corporation Lacrimal insert having reservoir with controlled release of medication and method of manufacturing the same
EP1778198A1 (en) 2004-07-26 2007-05-02 Clarity Corporation Implantable device having reservoir with controlled release of medication and method of manufacturing the same
US20080038317A1 (en) 2004-09-10 2008-02-14 Chin-Ming Chang Therapeutic Lacrimal Canalicular Inserts And Related Methods
US20060074370A1 (en) 2004-09-24 2006-04-06 Medennium, Inc. Ocular occluder and method of insertion
BRPI0518582A2 (pt) 2004-11-24 2008-11-25 Therakine Corp implante para liberaÇço de medicamento intra-ocular
US20060233858A1 (en) 2005-03-08 2006-10-19 Allergan, Inc. Systems and methods providing targeted intraocular drug delivery
WO2006122414A1 (en) 2005-05-17 2006-11-23 Matregen Corp. Depot for sustained and controlled delivery of methotrexate
WO2007009061A2 (en) 2005-07-13 2007-01-18 Anthrogenesis Corporation Ocular plug formed from placenta derived collagen biofabric
US7862532B2 (en) 2005-10-07 2011-01-04 Delta Life Sciences, Inc. Punctum plugs having insertion guides and strengthening beams
US20070132125A1 (en) 2005-12-08 2007-06-14 Bausch & Lomb Incorporated Use of a super-cooled fluid in lens processing
JP4078371B2 (ja) 2006-01-27 2008-04-23 章弘 小栗 涙点プラグ
BRPI0709663A2 (pt) 2006-03-31 2011-07-26 Qlt Plug Delivery Inc mÉtodos de liberaÇço de drogas, estruturas e composiÇÕes para um sistema nasolacrimal
US9173773B2 (en) 2006-06-21 2015-11-03 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
US20080045911A1 (en) 2006-06-21 2008-02-21 Borgia Maureen J Punctal plugs for the delivery of active agents
US9474645B2 (en) 2006-06-21 2016-10-25 Johnson & Johnson Vision Care, Inc. Punctal plugs for the delivery of active agents
FR2908042B1 (fr) 2006-11-08 2009-06-05 Bruno Fayet Ensemble d'intubation monocanaliculonasal et/ou monocanaliculaire,notamment pour l'imperforation lacrymonasale.
RU2009128703A (ru) * 2006-12-26 2011-02-10 Клт Плаг Диливери, Инк. (Us) Имплантаты, доставляющие лекарства, для уменьшения оптических дефектов
UY30883A1 (es) 2007-01-31 2008-05-31 Alcon Res Tapones punctales y metodos de liberacion de agentes terapeuticos
US20080299176A1 (en) 2007-05-30 2008-12-04 Yu-Chin Lai Drug delivery device comprising crosslinked polyurethane-siloxane-containing copolymers
CN102112076B (zh) * 2007-09-07 2015-04-22 马缇医疗股份有限公司 泪腺植入物及相关方法
DK2865361T3 (da) * 2007-09-07 2019-07-08 Mati Therapeutics Inc Tåreimplantater og tilhørende fremgangsmåder
WO2009035565A1 (en) 2007-09-07 2009-03-19 Qlt Plug Delivery, Inc Prostaglandin analogues for implant devices and methods
CN101969897A (zh) 2007-09-07 2011-02-09 Qlt栓塞输送公司 用于泪腺植入物的插入和抽出工具
KR20100067099A (ko) 2007-09-07 2010-06-18 큐엘티 플러그 딜리버리, 인코포레이티드 눈물 임플랜트 검출
ES2538838T3 (es) 2007-09-07 2015-06-24 Mati Therapeutics Inc. Método para preparar insertos de fármacos para liberación sostenida de agentes terapéuticos
US20100310622A1 (en) * 2007-12-17 2010-12-09 University Of Florida Research Foundation, Inc. Dry eye treatment by puncta plugs
NZ587335A (en) * 2008-02-18 2012-05-25 Quadra Logic Tech Inc Lacrimal implants and related methods with implant having drug core
CN104623741A (zh) 2008-04-30 2015-05-20 马缇医疗股份有限公司 复合泪管植入物及相关方法
US7846124B2 (en) * 2008-05-07 2010-12-07 Becker Bruce B Punctal anchor for lacrimal stent, introducer tool and method
CN102123713A (zh) * 2008-05-09 2011-07-13 Qlt栓塞输送公司 治疗青光眼和眼高血压的活性剂的持续释放递送
CN102119075A (zh) 2008-05-30 2011-07-06 Qlt栓塞输送公司 表面处理的可植入制品和相关方法
EP2303184A4 (en) 2008-06-24 2013-06-19 Quadra Logic Tech Inc GLAUCOMA ASSOCIATION TREATMENT
TW201006453A (en) * 2008-07-08 2010-02-16 Qlt Plug Delivery Inc Lacrimal implant body including comforting agent
CA2747556A1 (en) 2008-12-19 2010-06-24 Qlt Inc. Substance delivering punctum implants and methods
BRPI1007318A2 (pt) * 2009-01-23 2019-04-09 Qlt Inc. distribuição com liberação sustentada de um ou mais agentes.
EP3415124A3 (en) * 2009-02-23 2019-02-27 Mati Therapeutics Inc. Lacrimal implants
WO2011066479A1 (en) * 2009-11-27 2011-06-03 Qlt Plug Delivery, Inc. Lacrimal implants including split and insertable drug core
US9974685B2 (en) * 2011-08-29 2018-05-22 Mati Therapeutics Drug delivery system and methods of treating open angle glaucoma and ocular hypertension
JP6100782B2 (ja) * 2011-08-29 2017-03-22 キューエルティー インコーポレイテッド 緑内障および高眼圧症を治療するための活性剤の徐放送達
EP3652633B1 (en) 2017-07-14 2024-03-06 Canon Production Printing Holding B.V. Roll-fed printing apparatus, raster image processor, software medium, method for controlling a roll-fed printing apparatus, and method for controlling the raster image processor

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US20170202853A1 (en) 2017-07-20
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US20130053794A1 (en) 2013-02-28
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