DK3114225T3 - Sammensætning og fremgangsmåde til stabilisering af nukleinsyrer i biologiske prøver - Google Patents
Sammensætning og fremgangsmåde til stabilisering af nukleinsyrer i biologiske prøver Download PDFInfo
- Publication number
- DK3114225T3 DK3114225T3 DK15758044.0T DK15758044T DK3114225T3 DK 3114225 T3 DK3114225 T3 DK 3114225T3 DK 15758044 T DK15758044 T DK 15758044T DK 3114225 T3 DK3114225 T3 DK 3114225T3
- Authority
- DK
- Denmark
- Prior art keywords
- stabilization
- procedure
- composition
- nucleic acids
- biological samples
- Prior art date
Links
- 239000012472 biological sample Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 230000006641 stabilisation Effects 0.000 title 1
- 238000011105 stabilization Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/713—Double-stranded nucleic acids or oligonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461949692P | 2014-03-07 | 2014-03-07 | |
| US201462057769P | 2014-09-30 | 2014-09-30 | |
| PCT/CA2015/050173 WO2015131291A1 (en) | 2014-03-07 | 2015-03-06 | Composition and method for stabilizing nucleic acids in biological samples |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3114225T3 true DK3114225T3 (da) | 2021-07-26 |
Family
ID=54054312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK15758044.0T DK3114225T3 (da) | 2014-03-07 | 2015-03-06 | Sammensætning og fremgangsmåde til stabilisering af nukleinsyrer i biologiske prøver |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US10435735B2 (da) |
| EP (1) | EP3114225B1 (da) |
| JP (1) | JP6670765B2 (da) |
| KR (1) | KR102392407B1 (da) |
| CN (1) | CN106255753B (da) |
| AU (1) | AU2015226811B2 (da) |
| CA (1) | CA2941764C (da) |
| DK (1) | DK3114225T3 (da) |
| ES (1) | ES2880310T3 (da) |
| IL (1) | IL247662B2 (da) |
| MX (1) | MX375482B (da) |
| PL (1) | PL3114225T3 (da) |
| PT (1) | PT3114225T (da) |
| RU (1) | RU2717644C2 (da) |
| SA (2) | SA521421271B1 (da) |
| SG (2) | SG10201807736SA (da) |
| WO (1) | WO2015131291A1 (da) |
| ZA (1) | ZA201906139B (da) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| EP3150702B1 (en) | 2011-06-19 | 2021-05-19 | DNA Genotek, Inc. | Devices, solutions and methods for sample collection |
| US10435735B2 (en) * | 2014-03-07 | 2019-10-08 | Dna Genotek Inc. | Composition and method for stabilizing nucleic acids in biological samples |
| US12265089B2 (en) | 2014-09-11 | 2025-04-01 | Board Of Regents Of The University Of Texas System | Discriminating Parkinson's disease from multiple system atrophy using alpha-synuclein PMCA |
| CA3005963A1 (en) * | 2015-09-09 | 2017-03-16 | uBiome, Inc. | Method and system for microbiome-derived diagnostics and therapeutics for bacterial vaginosis |
| CA3055981A1 (en) | 2017-03-15 | 2018-09-20 | Ancestry.Com Dna, Llc | Sample collection device and method |
| AU2018345714A1 (en) | 2017-10-06 | 2020-05-21 | Ancestry.Com Dna, Llc | Systems, devices, and methods for sample collection |
| US11426734B2 (en) | 2017-11-22 | 2022-08-30 | Ancestry.Com Dna, Llc | Sample collection kit including cap having selectively movable sleeve |
| EP3713498A4 (en) | 2017-11-22 | 2021-08-04 | Ancestry.com DNA, LLC | SAMPLE COLLECTION KIT INCLUDING A CAP WITH A SELECTIVELY MOBILE SLEEVE |
| CN107955810A (zh) * | 2017-12-25 | 2018-04-24 | 宁波卡尔新材料科技有限公司 | 一种新型动物肝脏核酸提取试剂盒及提取方法 |
| WO2019159167A1 (en) | 2018-02-14 | 2019-08-22 | Salignostics Ltd. | Methods and apparatus for detecting analytes |
| CN108893523A (zh) * | 2018-05-31 | 2018-11-27 | 厦门安捷致善医学数据科技有限公司 | 一种粪便样品常温保存液 |
| EP3880689A4 (en) * | 2018-11-14 | 2022-08-31 | Spectrum Solutions L.L.C. | RNA PRESERVATION SOLUTION AND METHODS OF PREPARING AND USING THEREOF |
| US11714088B2 (en) * | 2019-02-19 | 2023-08-01 | Univerisy of South Carolina | Early detection of colorectal cancer |
| US11482306B2 (en) | 2019-02-27 | 2022-10-25 | Ancestry.Com Dna, Llc | Graphical user interface displaying relatedness based on shared DNA |
| CN109810974B (zh) * | 2019-04-08 | 2020-11-24 | 珠海丽珠试剂股份有限公司 | 提取人类免疫缺陷病毒hiv-1核酸的试剂组合产品及其方法 |
| AU2020343654A1 (en) | 2019-09-05 | 2022-03-31 | The Regents Of The University Of California | Noninvasive method to quantify kidney function and functional decline |
| CN113186185B (zh) * | 2020-01-14 | 2023-05-26 | 东北林业大学 | 一种从哺乳动物粪便中高效富集宿主dna的方法 |
| WO2021150775A1 (en) * | 2020-01-21 | 2021-07-29 | Board Of Regents Of The University Of Texas System | Discriminating parkinson's disease from multiple system atrophy using alpha-synuclein pmca |
| JP7555858B2 (ja) | 2020-03-11 | 2024-09-25 | 花王株式会社 | 皮膚表上脂質由来ｒｎａの調製方法 |
| US20220064709A1 (en) * | 2020-09-01 | 2022-03-03 | Longhorn Vaccines And Diagnostics, Llc | Compositions and Methods for Screening Biological Samples |
| US20240002905A1 (en) * | 2020-11-11 | 2024-01-04 | Biocept, Inc. | Pathogen inactivating and nucleic acid stabilization media for microorganism collection and transport |
| EP4263383A4 (en) | 2020-12-17 | 2024-10-23 | Nephrosant, Inc. | KITS FOR STABILIZATION OF URINE SAMPLES |
| CN114847272A (zh) * | 2021-02-03 | 2022-08-05 | 上海究本生物科技有限公司 | 一种稳定化生物学样本遗传信息物质的组合物 |
| KR20230171989A (ko) * | 2021-04-16 | 2023-12-21 | 그리폴스 다이어그노스틱 솔루션즈 인크. | 생물학적 샘플을 저장하기 위한 조성물 및 방법 |
| US20240341302A1 (en) * | 2021-08-09 | 2024-10-17 | University Of Central Florida Research Foundation, Inc. | Method to preserve nucleic acids in water samples |
| KR102750700B1 (ko) * | 2021-12-30 | 2025-01-09 | 주식회사 랩 지노믹스 | 생물학적 샘플 내 핵산의 안정화 또는 추출용 조성물 및 이를 이용한 방법 |
| US20250149114A1 (en) * | 2022-02-10 | 2025-05-08 | Dna Genotek Inc. | Methods and systems for defining test sample read count limits for a range of microbial sequence reads |
| US12332902B2 (en) | 2022-04-20 | 2025-06-17 | Ancestry.Com Dna, Llc | Filtering individual datasets in a database |
| CN115728110A (zh) * | 2022-11-24 | 2023-03-03 | 海军军医大学第一附属医院 | 一种改进试剂盒粪便样本萃取的方法 |
Family Cites Families (99)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4663161A (en) * | 1985-04-22 | 1987-05-05 | Mannino Raphael J | Liposome methods and compositions |
| GB8614084D0 (en) * | 1986-06-10 | 1986-07-16 | Serono Diagnostics Ltd | Immunoassay |
| US4918178A (en) | 1987-10-22 | 1990-04-17 | Wisconsin Alumni Research Foundation | Test for Johne's disease |
| JP2791367B2 (ja) | 1988-04-21 | 1998-08-27 | マイクロプローブ・コーポレーション | 核酸抽出方法 |
| JPH04187077A (ja) | 1990-11-22 | 1992-07-03 | Shimadzu Corp | 核酸の抽出精製装置 |
| JPH0599923A (ja) | 1991-10-11 | 1993-04-23 | Nitto Denko Corp | ヒトヘモグロビンの検出方法及びそれに用いる便溶解用緩衝液 |
| DE4204012A1 (de) * | 1992-02-12 | 1993-08-19 | Ulrich Prof Dr Zimmermann | Mitogenfreie substanz, deren herstellung und verwendung |
| EP0672181B1 (en) | 1992-04-01 | 2003-11-05 | The Johns Hopkins University School Of Medicine | Methods of detecting mammalian nucleic acids isolated from stool specimen and reagents therefor |
| DE4321904B4 (de) | 1993-07-01 | 2013-05-16 | Qiagen Gmbh | Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen |
| WO1995014768A2 (en) | 1993-11-29 | 1995-06-01 | Gen-Probe Incorporated | Method for extracting nucleic acids from a wide range of organisms |
| GB9506843D0 (en) | 1995-04-03 | 1995-05-24 | Chiroscience Ltd | Oxidative process and products thereof |
| DE19530132C2 (de) | 1995-08-16 | 1998-07-16 | Max Planck Gesellschaft | Verfahren zur Reinigung, Stabilisierung oder Isolierung von Nukleinsäuren aus biologischen Materialien |
| GB9518156D0 (en) | 1995-09-06 | 1995-11-08 | Medical Res Council | Method of isolating cells |
| NO954667D0 (no) | 1995-11-17 | 1995-11-17 | Dagfinn Oegreid | Fremgangsmåte til deteksjon av Ki-ras mutasjoner |
| EP0920535B1 (de) | 1996-08-26 | 2007-11-14 | Invitek Gesellschaft für Biotechnik & Biodesign mbH. | Verfahren zum nachweis klinisch relevanter veränderungen der dns-sequenz des ki-ras-onkogens, seine verwendung und testkit zur früherkennung von tumoren |
| WO1998012351A1 (de) | 1996-09-19 | 1998-03-26 | Roth W Kurt | Verfahren zur reinigung und gegebenenfalls analyse von nukleinsäuren aus biologischen proben |
| AU7816898A (en) | 1997-06-16 | 1999-01-04 | Exact Laboratories, Inc. | Methods for stool sample preparation |
| US6268136B1 (en) | 1997-06-16 | 2001-07-31 | Exact Science Corporation | Methods for stool sample preparation |
| AU2509799A (en) | 1997-12-18 | 1999-07-12 | Invitek Gmbh | Method for isolating short and long-chain nucleic acids |
| EP1053311B1 (en) | 1998-02-02 | 2007-11-28 | QIAGEN North American Holdings, Inc. | Compositions and methods for using a lysing matrix for isolating dna |
| EP0939118A1 (en) | 1998-02-20 | 1999-09-01 | Universiteit Maastricht | Method for isolating DNA and RNA from faeces |
| AU4934099A (en) | 1998-08-04 | 2000-02-28 | Center For Advanced Science And Technology Incubation, Ltd. | Method for enzymatic amplification of nucleic acid |
| WO2000029618A1 (en) | 1998-11-12 | 2000-05-25 | University Of Virginia Patent Foundation | Non-invasive detection of helicobacter pylori infection |
| DE19856064C2 (de) * | 1998-12-04 | 2000-11-30 | Invitek Gmbh | Universelles Verfahren zur Isolierung von DNA aus beliebigen Ausgangsmaterialien |
| DE19900638C2 (de) | 1999-01-11 | 2002-12-19 | Max Planck Gesellschaft | Methode zur Isolierung von DNA aus biologischen Materialien |
| DE60028732T2 (de) * | 1999-02-25 | 2007-06-14 | Exact Sciences Corp., Maynard | Verfahren zur erhaltung der dns-integrität |
| US20020004206A1 (en) | 1999-04-09 | 2002-01-10 | Berger Barry M. | Methods of screening for disease |
| EP1175431A4 (en) | 1999-04-30 | 2002-09-11 | Whatman Inc | SUBSTRATE CONTAINING ANIONIC NUCLEIC ACID PURIFICATION DETERGENT |
| US6270970B1 (en) * | 1999-05-14 | 2001-08-07 | Promega Corporation | Mixed-bed solid phase and its use in the isolation of nucleic acids |
| US6586177B1 (en) | 1999-09-08 | 2003-07-01 | Exact Sciences Corporation | Methods for disease detection |
| US6849403B1 (en) | 1999-09-08 | 2005-02-01 | Exact Sciences Corporation | Apparatus and method for drug screening |
| EP1238106A2 (en) | 1999-12-07 | 2002-09-11 | Exact Sciences Corporation | Apparatus and methods for drug screening based 0on nucleic acid analysis |
| US6919174B1 (en) | 1999-12-07 | 2005-07-19 | Exact Sciences Corporation | Methods for disease detection |
| ATE376067T1 (de) | 2000-02-04 | 2007-11-15 | Qiagen Gmbh | Nukleinsäure-isolierung aus stuhlproben und anderen biologischen materialien, die reich an inhibitoren sind |
| EP1254238B1 (de) * | 2000-02-09 | 2009-09-16 | Basf Se | Neues elongasegen und verfahren zur herstellung mehrfach ungesättigter fettsäuren |
| FR2808276B1 (fr) | 2000-04-26 | 2004-04-02 | Renaud Nalin | Procede d'extraction indirecte de l'adn d'organismes non cultivables et adn susceptible d'etre obtenu par ledit procede |
| DE10031236A1 (de) | 2000-06-27 | 2002-01-10 | Qiagen Gmbh | Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien |
| JP4599684B2 (ja) | 2000-07-26 | 2010-12-15 | 株式会社島津製作所 | 糞便からの核酸精製法 |
| CU23095A1 (es) * | 2000-11-07 | 2005-11-18 | Cnic Ct Nac Investigaciones | Proceso para la tipificación rápida de microorganismos y juego de reactivos empleado |
| US7029840B2 (en) | 2000-11-15 | 2006-04-18 | Becton, Dickinson And Company | Method for preservation of cells and nucleic acid targets |
| US6911308B2 (en) | 2001-01-05 | 2005-06-28 | Exact Sciences Corporation | Methods for detecting, grading or monitoring an H. pylori infection |
| DE10102338A1 (de) * | 2001-01-19 | 2002-07-25 | Basf Plant Science Gmbh | Verfahren zur Expression von Biosynthesegenen in pflanzlichen Samen unter Verwendung von neuen multiplen Expressionskonstrukten |
| AU2002356053A1 (en) | 2001-08-20 | 2003-03-03 | Whatman, Inc. | Dna purification and recovery from high particulate and solids samples |
| CA2463317A1 (en) | 2001-10-12 | 2003-04-24 | Gentra Systems, Inc. | Compositions and methods for using a solid support to purify rna |
| US7893228B2 (en) | 2001-10-12 | 2011-02-22 | Qiagen North American Holdings, Inc. | Compositions and methods for using a solid support to purify RNA |
| US7148343B2 (en) | 2001-10-12 | 2006-12-12 | Gentra Systems, Inc. | Compositions and methods for using a solid support to purify RNA |
| US20030109548A1 (en) * | 2001-11-09 | 2003-06-12 | Royt Paulette W. | Compositions and methods of treating iron excess |
| DE10222133A1 (de) | 2002-05-17 | 2003-12-04 | Gl Biotech Gmbh | Verfahren zur Nukleinsäure-Extraktion und Nukleinsäure-Reinigung |
| US20030215954A1 (en) | 2002-05-17 | 2003-11-20 | Cockerill Franklin R. | Nucleic acid recovery reagents and methods |
| AU2003232781A1 (en) | 2002-05-17 | 2003-12-02 | Gl Bio Tech Gmbh | Method for nucleic acid extraction and nucleic acid purification |
| EP1506995B1 (en) | 2002-05-21 | 2009-10-14 | ARKRAY, Inc. | Method of effecting lysis of acid-fast bacteria and method of performing gene amplification or detection therewith |
| JP4092141B2 (ja) | 2002-06-07 | 2008-05-28 | 株式会社島津製作所 | 核酸抽出同時精製法 |
| US6852495B2 (en) | 2002-06-06 | 2005-02-08 | Shimadzu Corporation | Process of extracting nucleic acid and process of simultaneously carrying out extraction and purification of nucleic acid |
| JP4092139B2 (ja) | 2002-06-06 | 2008-05-28 | 株式会社島津製作所 | 核酸抽出法 |
| US7482116B2 (en) * | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| EP1391520A1 (en) | 2002-08-20 | 2004-02-25 | Becton Dickinson and Company | Method for preservation of cells and nucleic acid targets |
| US20040157219A1 (en) | 2003-02-06 | 2004-08-12 | Jianrong Lou | Chemical treatment of biological samples for nucleic acid extraction and kits therefor |
| FR2861085B1 (fr) | 2003-10-15 | 2006-01-27 | Bertin Technologies Sa | Methode d'extraction d'acides nucleiques et son application dans l'analyse de la population microbienne de l'air |
| US20050239045A1 (en) | 2003-12-08 | 2005-10-27 | Arkray Inc. | Microorganism or cell collecting method, and microorganism or cell collecting implement used for the method |
| DE102004004901B4 (de) * | 2004-01-30 | 2006-01-05 | Johannes-Gutenberg-Universität Mainz | Verfahren zur Herstellung von Sorbicillacton A |
| WO2005113769A1 (en) | 2004-05-14 | 2005-12-01 | Exact Sciences Corporation | Method for stabilizing biological samples for nucleic acid analysis |
| ES2529044T3 (es) * | 2004-05-21 | 2015-02-16 | Mo Bio Laboratories, Inc. | Kits y procedimientos para eliminar contaminantes de ácidos nucleicos en muestras ambientales y biológicas |
| EP1758937B1 (en) | 2004-05-24 | 2009-09-02 | Genvault Corporation | Stable protein storage and stable nucleic acid storage in recoverable form |
| US20050277121A1 (en) | 2004-06-11 | 2005-12-15 | Ambion, Inc. | Crude biological derivatives competent for nucleic acid detection |
| AU2005305012C1 (en) * | 2004-11-05 | 2012-07-19 | Qiagen North American Holdings, Inc. | Compositions and methods for purifying nucleic acids from stabilization reagents |
| CA2587419C (en) * | 2004-11-17 | 2013-03-19 | Forensink Corporation Inc. | Compositions for marking objects with dna and methods for marking and linking an object to its owner |
| US8158357B2 (en) | 2005-03-16 | 2012-04-17 | Dna Genotek Inc. | Compositions and method for storage of nucleic acid from bodily fluids |
| US20070141582A1 (en) | 2005-12-15 | 2007-06-21 | Weiwei Li | Method and kit for detection of early cancer or pre-cancer using blood and body fluids |
| JP2007248170A (ja) * | 2006-03-15 | 2007-09-27 | Hitachi Ltd | 糞便懸濁液作製用容器 |
| WO2008021995A1 (en) | 2006-08-10 | 2008-02-21 | Cohen Ariel B | Methods and compositions for detecting an analyte in a biological sample |
| US8080645B2 (en) * | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| NZ576003A (en) | 2006-10-06 | 2012-03-30 | Dna Genotek Inc | Stabilizing compositions and methods for extraction of ribonucleic acid |
| US20080286831A1 (en) | 2007-01-15 | 2008-11-20 | Greg Liang | Sample collector and tester |
| WO2008152980A1 (ja) | 2007-06-12 | 2008-12-18 | Olympus Corporation | 生物学的試料と試薬との混合用容器及び生物学的試料と試薬との混合方法 |
| ES2552858T3 (es) | 2007-10-01 | 2015-12-02 | Longhorn Vaccines And Diagnostics, Llc | Recogida de muestras biológicas y sistema de transporte y métodos de uso |
| WO2009057695A1 (ja) | 2007-10-30 | 2009-05-07 | Olympus Corporation | 遺伝子解析による腺腫又はがんの検出方法 |
| US9347055B2 (en) | 2007-11-05 | 2016-05-24 | Eiken Kagaku Kabushiki Kaisha | Method and kit for preparation of sample for use in nucleic acid amplification |
| CN101952460A (zh) | 2007-11-20 | 2011-01-19 | 奥林巴斯株式会社 | 用于制备粪便样品的方法、制备粪便样品用溶液和采集粪便用试剂盒 |
| ES2522542T3 (es) | 2008-02-15 | 2014-11-17 | Mayo Foundation For Medical Education And Research | Detección de neoplasia a partir de una muestra de heces |
| JPWO2009133928A1 (ja) | 2008-05-02 | 2011-09-01 | アークレイ株式会社 | 白血球の分析方法およびそれに使用する分析試薬 |
| CN102027132A (zh) | 2008-05-12 | 2011-04-20 | 奥林巴斯株式会社 | 粪便处理方法及粪便处理容器 |
| JP5710969B2 (ja) | 2008-07-23 | 2015-04-30 | オリンパス株式会社 | 糞便試料からの核酸回収方法 |
| JPWO2010024251A1 (ja) | 2008-08-26 | 2012-01-26 | オリンパス株式会社 | 糞便試料の調製方法、糞便試料調製用溶液、及び採便用キット |
| US20100121046A1 (en) * | 2008-09-05 | 2010-05-13 | Mayo Foundation For Medical Education And Research | Collecting and processing complex macromolecular mixtures |
| US8405379B1 (en) | 2008-09-18 | 2013-03-26 | Luc Montagnier | System and method for the analysis of DNA sequences in biological fluids |
| WO2010064628A1 (ja) | 2008-12-05 | 2010-06-10 | オリンパス株式会社 | 核酸含有試料の調製方法、試料調製用溶液、及び核酸の解析方法 |
| JPWO2010064634A1 (ja) | 2008-12-05 | 2012-05-10 | オリンパス株式会社 | 糞便試料の調製方法、糞便試料調製用溶液、及び採便用キット |
| US8427428B2 (en) | 2009-03-31 | 2013-04-23 | Key Ovation Llc | Adjustable ergonomic keyboard |
| JPWO2010134246A1 (ja) | 2009-05-20 | 2012-11-08 | オリンパス株式会社 | 核酸含有試料の調製方法 |
| JPWO2010134245A1 (ja) | 2009-05-20 | 2012-11-08 | オリンパス株式会社 | 哺乳細胞由来核酸の回収方法、核酸解析方法、及び採便用キット |
| JP2011250757A (ja) | 2010-06-03 | 2011-12-15 | Olympus Corp | 生体試料中の核酸検出方法 |
| US9845489B2 (en) | 2010-07-26 | 2017-12-19 | Biomatrica, Inc. | Compositions for stabilizing DNA, RNA and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| US9376709B2 (en) | 2010-07-26 | 2016-06-28 | Biomatrica, Inc. | Compositions for stabilizing DNA and RNA in blood and other biological samples during shipping and storage at ambient temperatures |
| BR112013002667B1 (pt) | 2010-08-04 | 2020-02-04 | Thomas Julius Borody | composições para transplante da flora intestinal e métodos para fazê-las e usá-las e dispositivos para administrá-las |
| WO2012044581A1 (en) | 2010-10-01 | 2012-04-05 | Esoterix Genetic Laboratories, Llc | Enrichment of low molecular weight dna |
| US8530228B2 (en) | 2010-12-28 | 2013-09-10 | Bexmart | Integrated versatile and systems preparation of specimens |
| US9198609B2 (en) | 2011-04-19 | 2015-12-01 | Porex Corporation | Cards for sample storage and delivery comprising sintered porous plastic |
| US20130071847A1 (en) | 2011-09-19 | 2013-03-21 | BioPet Vet Lab | Methods and materials for determining the source of waste |
| US10435735B2 (en) * | 2014-03-07 | 2019-10-08 | Dna Genotek Inc. | Composition and method for stabilizing nucleic acids in biological samples |
-
2015
- 2015-03-06 US US15/124,060 patent/US10435735B2/en active Active
- 2015-03-06 RU RU2016138077A patent/RU2717644C2/ru active
- 2015-03-06 PT PT157580440T patent/PT3114225T/pt unknown
- 2015-03-06 SG SG10201807736SA patent/SG10201807736SA/en unknown
- 2015-03-06 ES ES15758044T patent/ES2880310T3/es active Active
- 2015-03-06 JP JP2016572863A patent/JP6670765B2/ja active Active
- 2015-03-06 CN CN201580015964.6A patent/CN106255753B/zh active Active
- 2015-03-06 PL PL15758044T patent/PL3114225T3/pl unknown
- 2015-03-06 SG SG11201607364RA patent/SG11201607364RA/en unknown
- 2015-03-06 IL IL247662A patent/IL247662B2/en unknown
- 2015-03-06 CA CA2941764A patent/CA2941764C/en active Active
- 2015-03-06 DK DK15758044.0T patent/DK3114225T3/da active
- 2015-03-06 AU AU2015226811A patent/AU2015226811B2/en active Active
- 2015-03-06 MX MX2016011495A patent/MX375482B/es active IP Right Grant
- 2015-03-06 EP EP15758044.0A patent/EP3114225B1/en active Active
- 2015-03-06 WO PCT/CA2015/050173 patent/WO2015131291A1/en active Application Filing
- 2015-03-06 KR KR1020167027593A patent/KR102392407B1/ko active Active
-
2016
- 2016-09-05 SA SA521421271A patent/SA521421271B1/ar unknown
- 2016-09-05 SA SA516371797A patent/SA516371797B1/ar unknown
-
2019
- 2019-09-17 ZA ZA2019/06139A patent/ZA201906139B/en unknown
- 2019-10-07 US US16/595,273 patent/US11198899B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK3114225T3 (da) | Sammensætning og fremgangsmåde til stabilisering af nukleinsyrer i biologiske prøver | |
| DK3882357T3 (da) | Fremgangsmåder og sammensætninger til analyse af nukleinsyrer | |
| EP3129035C0 (en) | COMPOSITIONS AND METHODS FOR INDUCING TH17 CELLS | |
| DK3325669T3 (da) | Sammensætninger og fremgangsmåder til RNA-analyse | |
| DK3307872T3 (da) | Fremgangsmåder og sammensætninger til effektiv indgivelse af nukleinsyrer og rna-baserede antimikrober | |
| DK3386550T3 (da) | Fremgangsmåder til fremstilling og anvendelse af guide nukleinsyrer | |
| DK3158054T3 (da) | Genetisk modificerede bakterier og fremgangsmåder til genetisk modifikation af bakterier | |
| DK3212778T3 (da) | Fremgangsmåder og sammensætninger til stabilisering af trans-splejsning af intein-modificerede proteaser | |
| DK3102673T3 (da) | Fremgangsmåder og sammensætninger til behandling af beta-talassæmi | |
| DK3204413T3 (da) | Bærerantistofsammensætninger og fremgangsmåder til fremstilling og anvendelse heraf | |
| DK3234133T3 (da) | Crispr-baserede sammensætninger og fremgangsmåder til anvendelse | |
| DK3394065T3 (da) | Tetrahydropyranyl-amino-pyrrolopyrimidinon og fremgangsmåder til anvendelse deraf | |
| DK3428290T3 (da) | Sammensætninger og fremgangsmåder til amplifikation af nukleinsyrer | |
| DK3134130T3 (da) | Sammensætninger og fremgangsmåder til behandling af hæmoglobinopatier | |
| DK3240895T3 (da) | Sammensætninger og fremgangsmåder til proteinglykosylering | |
| PL3274469T3 (pl) | Kompozycje i sposoby wykrywania zanieczyszczenia biologicznego | |
| DK3144001T3 (da) | Sammensætninger af selenoorganiske forbindelser og fremgangsmåder til anvendelse deraf | |
| DK3699289T3 (da) | Prøveklargøring til nukleinsyreamplifikation | |
| DK3129779T3 (da) | Fremgangsmåder og sammensætninger til påvisning af fejlfoldede proteiner | |
| DK3495482T3 (da) | Fremgangsmåde til fremstilling af dna-enhedssammensætning og fremgangsmåde til frembringelse af concatenat-dna | |
| DK3357343T3 (da) | Fedtsammensætning og fremgangsmåde til fremstilling heraf | |
| DK3307878T3 (da) | Fremgangsmåder til fremstilling og oprensning af nukleinsyreholdige sammensætninger | |
| DK3232777T3 (da) | Konservering og transport af en biologisk ex-vivo-prøve under anvendelse af ultralyd | |
| IL254827A0 (en) | Encapsulating methods and materials for biological samples | |
| DK3137479T3 (da) | Oligonukleotidsammensætninger og fremgangsmåder til fremstilling af disse |