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DK3182980T3 - Behandling af glykosyleringsmangelsygdomme - Google Patents

Behandling af glykosyleringsmangelsygdomme Download PDF

Info

Publication number
DK3182980T3
DK3182980T3 DK15833822.8T DK15833822T DK3182980T3 DK 3182980 T3 DK3182980 T3 DK 3182980T3 DK 15833822 T DK15833822 T DK 15833822T DK 3182980 T3 DK3182980 T3 DK 3182980T3
Authority
DK
Denmark
Prior art keywords
glycosyling
treatment
deficiency diseases
deficiency
diseases
Prior art date
Application number
DK15833822.8T
Other languages
English (en)
Inventor
Borstel Reid W Von
Original Assignee
Wellstat Therapeutics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellstat Therapeutics Corp filed Critical Wellstat Therapeutics Corp
Application granted granted Critical
Publication of DK3182980T3 publication Critical patent/DK3182980T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004Monosaccharides having only carbon, hydrogen and oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7012Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK15833822.8T 2014-08-19 2015-08-19 Behandling af glykosyleringsmangelsygdomme DK3182980T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201462039052P 2014-08-19 2014-08-19
PCT/US2015/045896 WO2016028894A1 (en) 2014-08-19 2015-08-19 Treatment of glycosylation deficiency diseases

Publications (1)

Publication Number Publication Date
DK3182980T3 true DK3182980T3 (da) 2021-01-11

Family

ID=55351228

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15833822.8T DK3182980T3 (da) 2014-08-19 2015-08-19 Behandling af glykosyleringsmangelsygdomme

Country Status (6)

Country Link
US (2) US20170209476A1 (da)
EP (1) EP3182980B1 (da)
DK (1) DK3182980T3 (da)
ES (1) ES2841745T3 (da)
PL (1) PL3182980T3 (da)
WO (1) WO2016028894A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112020013342A2 (pt) * 2018-02-01 2020-12-01 Wellstat Therapeutics Corporation composições e dispositivos para fornecimento sistêmico de uridina
EP4190334A1 (en) * 2018-06-14 2023-06-07 Mayo Foundation for Medical Education and Research Methods and materials for treating glycosylation disorders
WO2022056428A1 (en) * 2020-09-14 2022-03-17 Wellstat Therapeutics Corporation 2',3'-diacetyluridine substituted with acetoacetyl at the 5' position

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1171137E (pt) * 1999-02-23 2008-03-17 Univ California Utilização de triacetiluridina para o tratamento de perturbações mitocondriais
WO2007064691A1 (en) * 2005-12-02 2007-06-07 Nabil Habib Lab Treatment of cancer and other diseases
US20120078529A1 (en) * 2009-05-13 2012-03-29 Wellstat Therapeutics Corporation Determining the severity of 5-fluorouracil overdose
US20110257233A1 (en) * 2010-03-19 2011-10-20 Sanford-Burnham Medical Research Institute Benzoisothiazolones as inhibitors of phosphomannose isomerase
JP2015503924A (ja) * 2012-01-05 2015-02-05 ハダシット メディカル リサーチ サービシーズ アンド ディベロップメント リミテッド 遺伝子導入のための方法及び組成物

Also Published As

Publication number Publication date
EP3182980A1 (en) 2017-06-28
US20220273688A1 (en) 2022-09-01
EP3182980B1 (en) 2020-10-14
US20170209476A1 (en) 2017-07-27
PL3182980T3 (pl) 2021-04-19
EP3182980A4 (en) 2018-06-06
WO2016028894A1 (en) 2016-02-25
ES2841745T3 (es) 2021-07-09

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