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DK2970345T3 - 18f-mærkede psma-targeterede pet-kontrastmidler - Google Patents

18f-mærkede psma-targeterede pet-kontrastmidler Download PDF

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Publication number
DK2970345T3
DK2970345T3 DK14721640.2T DK14721640T DK2970345T3 DK 2970345 T3 DK2970345 T3 DK 2970345T3 DK 14721640 T DK14721640 T DK 14721640T DK 2970345 T3 DK2970345 T3 DK 2970345T3
Authority
DK
Denmark
Prior art keywords
contractors
labeled psma
psma targeted
targeted pet
pet
Prior art date
Application number
DK14721640.2T
Other languages
English (en)
Inventor
Clifford Berkman
Svetlana A Stekhova
Original Assignee
Cancer Targeted Tech Llc
Univ Washington State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Targeted Tech Llc, Univ Washington State filed Critical Cancer Targeted Tech Llc
Application granted granted Critical
Publication of DK2970345T3 publication Critical patent/DK2970345T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0489Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0402Organic compounds carboxylic acid carriers, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2404Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2404Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2416Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/22Amides of acids of phosphorus
    • C07F9/24Esteramides
    • C07F9/2454Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2458Esteramides the amide moiety containing a substituent or a structure which is considered as characteristic of aliphatic amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK14721640.2T 2013-03-15 2014-03-14 18f-mærkede psma-targeterede pet-kontrastmidler DK2970345T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361798108P 2013-03-15 2013-03-15
PCT/US2014/027820 WO2014143736A1 (en) 2013-03-15 2014-03-14 18f-labeled psma-targeted pet imaging agents

Publications (1)

Publication Number Publication Date
DK2970345T3 true DK2970345T3 (da) 2019-08-26

Family

ID=50639969

Family Applications (2)

Application Number Title Priority Date Filing Date
DK14721640.2T DK2970345T3 (da) 2013-03-15 2014-03-14 18f-mærkede psma-targeterede pet-kontrastmidler
DK19179758.8T DK3560937T3 (da) 2013-03-15 2014-03-14 Fremgangsmåder til fremstilling af 18f-mærkede psma-målrettede billeddannelsesmidler og diagnostiske fremgangsmåder dermed

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK19179758.8T DK3560937T3 (da) 2013-03-15 2014-03-14 Fremgangsmåder til fremstilling af 18f-mærkede psma-målrettede billeddannelsesmidler og diagnostiske fremgangsmåder dermed

Country Status (16)

Country Link
US (2) US11554183B2 (da)
EP (3) EP3560937B1 (da)
CN (2) CN105308056B (da)
AU (2) AU2014228233B2 (da)
CA (1) CA2903131C (da)
DK (2) DK2970345T3 (da)
ES (2) ES2743433T3 (da)
FI (1) FI3560937T3 (da)
HR (2) HRP20230109T1 (da)
HU (2) HUE061402T2 (da)
LT (2) LT3560937T (da)
PL (2) PL2970345T3 (da)
PT (2) PT3560937T (da)
RS (1) RS64011B1 (da)
SI (2) SI3560937T1 (da)
WO (1) WO2014143736A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017027870A1 (en) * 2015-08-13 2017-02-16 The Johns Hopkins University Triazole conjugated ureas, thioureas, carbamates, and "reversed" carbamates for psma-targeted imaging agents and uses thereof
EP3497108A1 (en) * 2016-08-10 2019-06-19 Cancer Targeted Technology LLC Chelated psma inhibitors
WO2018175646A1 (en) 2017-03-22 2018-09-27 Safeop Surgical, Inc. Medical systems and methods for detecting changes in electrophysiological evoked potentials
KR20200009091A (ko) 2017-05-24 2020-01-29 아이티엠 이소토펜 테크놀로지엔 뮌헨 아게 신규 psma-결합제 및 이의 용도
WO2018233798A1 (en) 2017-06-20 2018-12-27 ITM Isotopen Technologien München AG NOVEL PSMA BINDING AGENTS AND USE THEREOF
WO2020108753A1 (en) 2018-11-28 2020-06-04 ITM Isotopen Technologien München AG Novel tumor antigen binding agents and uses thereof
WO2020224780A1 (en) 2019-05-08 2020-11-12 ITM Isotopen Technologien München AG Para-aminohippuric acid (pah) as a renal protective substance
WO2021046233A1 (en) 2019-09-03 2021-03-11 Cancer Targeted Technology Llc Chelate-containing psma inhibitors
WO2022096103A1 (en) 2020-11-05 2022-05-12 ITM Isotopen Technologien München AG Combination of para-aminohippuric acid (pah) and radiolabeled complexes for treating cancer
WO2022111800A1 (en) 2020-11-25 2022-06-02 Itm Solucin Gmbh Stable formulations for radionuclide complexes
TW202304531A (zh) 2021-04-02 2023-02-01 法商先進加速器應用公司 放射性配體顯像劑在前列腺癌的用途及注射或輸液用溶液

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009532338A (ja) * 2006-03-14 2009-09-10 キャンサー ターゲテッド テクノロジー エルエルシー Psmaのペプチド模倣体阻害剤、それらを含む化合物、およびそれらの使用方法
EP2063918B1 (en) * 2006-09-08 2014-02-26 Piramal Imaging SA Compounds and methods for 18f labeled agents
CA2732632C (en) * 2008-08-01 2018-01-09 The Johns Hopkins University Psma-binding agents and uses thereof
US9328129B2 (en) * 2010-11-12 2016-05-03 Washington State University Peptidomimetic inhibitors of PSMA
EP2721039B1 (en) * 2011-06-15 2018-01-10 Cancer Targeted Technology LLC Chelated psma inhibitors
CN102757296B (zh) * 2012-04-10 2014-11-19 中国科学院上海应用物理研究所 一种对化合物进行[18f]标记的方法
WO2013173630A1 (en) 2012-05-16 2013-11-21 Cancer Targeted Technology, Llc Formulation of radiopharmaceuticals containing multiple acidic groups
WO2013173583A1 (en) 2012-05-16 2013-11-21 Cancer Targeted Technology, Llc Psma inhibitors

Also Published As

Publication number Publication date
US20230144322A1 (en) 2023-05-11
FI3560937T3 (fi) 2023-02-28
LT3560937T (lt) 2023-03-27
SI3560937T1 (sl) 2023-04-28
EP3560937B1 (en) 2022-12-28
PL2970345T3 (pl) 2019-12-31
US20160030605A1 (en) 2016-02-04
CA2903131C (en) 2021-11-23
SI2970345T1 (sl) 2019-11-29
PT2970345T (pt) 2019-09-06
EP4180438A1 (en) 2023-05-17
LT2970345T (lt) 2019-09-25
PL3560937T3 (pl) 2023-03-27
DK3560937T3 (da) 2023-02-13
HUE046194T2 (hu) 2020-02-28
EP2970345B1 (en) 2019-06-19
AU2014228233A1 (en) 2015-09-17
CA2903131A1 (en) 2014-09-18
CN105308056A (zh) 2016-02-03
EP2970345A1 (en) 2016-01-20
AU2014228233B2 (en) 2019-02-28
HUE061402T2 (hu) 2023-06-28
ES2937955T3 (es) 2023-04-03
AU2019203610A1 (en) 2019-06-13
WO2014143736A1 (en) 2014-09-18
CN108558939B (zh) 2021-08-24
CN108558939A (zh) 2018-09-21
CN105308056B (zh) 2018-03-20
EP3560937A1 (en) 2019-10-30
US11554183B2 (en) 2023-01-17
RS64011B1 (sr) 2023-03-31
HRP20230109T1 (hr) 2023-04-28
PT3560937T (pt) 2023-02-13
AU2019203610B2 (en) 2021-02-04
HRP20191482T1 (hr) 2019-11-15
ES2743433T3 (es) 2020-02-19

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