DK2953957T3 - Modificerede glycolipider og fremgangsmåder til fremstilling og brug af disse - Google Patents

Modificerede glycolipider og fremgangsmåder til fremstilling og brug af disse Download PDF

Info

Publication number: DK2953957T3
Authority: DK; Denmark
Prior art keywords: glycolipides; preparing; modified; methods; modified glycolipides
Prior art date: 2013-02-08

Application number

DK14706210.3T

Other languages

English (en)

Inventor

Steven A Porcelli

Maurice Zauderer

Original Assignee

Vaccinex Inc

Albert Einstein College Medicine Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-02-08

Filing date

2014-02-07

Publication date

2019-07-22

2013-03-14 Priority claimed from US13/803,972 external-priority patent/US9371352B2/en

2014-02-07 Application filed by Vaccinex Inc, Albert Einstein College Medicine Inc filed Critical Vaccinex Inc

2019-07-22 Application granted granted Critical

2019-07-22 Publication of DK2953957T3 publication Critical patent/DK2953957T3/da

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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Virology (AREA)
Bioinformatics & Cheminformatics (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Tropical Medicine & Parasitology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Neurology (AREA)
Dermatology (AREA)
Rheumatology (AREA)
Obesity (AREA)
Hematology (AREA)
Endocrinology (AREA)
AIDS & HIV (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Transplantation (AREA)
Emergency Medicine (AREA)
Heart & Thoracic Surgery (AREA)

DK14706210.3T 2013-02-08 2014-02-07 Modificerede glycolipider og fremgangsmåder til fremstilling og brug af disse DK2953957T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201361762591P	2013-02-08	2013-02-08
US13/803,972 US9371352B2 (en)	2013-02-08	2013-03-14	Modified glycolipids and methods of making and using the same
US201361842149P	2013-07-02	2013-07-02
PCT/US2014/015286 WO2014124245A1 (en)	2013-02-08	2014-02-07	Modified glycolipids and methods of making and using the same

Publications (1)

Publication Number	Publication Date
DK2953957T3 true DK2953957T3 (da)	2019-07-22

Family

ID=51300153

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK14706210.3T DK2953957T3 (da)	2013-02-08	2014-02-07	Modificerede glycolipider og fremgangsmåder til fremstilling og brug af disse

Country Status (10)

Country	Link
EP (1)	EP2953957B1 (da)
JP (1)	JP6487854B2 (da)
KR (1)	KR102167438B1 (da)
CN (1)	CN105339379B (da)
AU (1)	AU2014214770B2 (da)
CA (1)	CA2900524A1 (da)
DK (1)	DK2953957T3 (da)
ES (1)	ES2730649T3 (da)
NZ (1)	NZ710949A (da)
WO (1)	WO2014124245A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9809654B2 (en)	2002-09-27	2017-11-07	Vaccinex, Inc.	Targeted CD1d molecules
EP2112930B1 (en)	2007-02-21	2017-01-11	Vaccinex, Inc.	Modulation of nkt cell activity with antigen-loaded cdid molecules
CN108530517A (zh) *	2017-03-01	2018-09-14	拜西欧斯（北京）生物技术有限公司	刺激免疫细胞活化的多肽、融合蛋白及其制备方法
CN107522760A (zh) *	2017-08-21	2017-12-29	河南师范大学	具有免疫活性的α‑GalCer磷酸酯类化合物及其合成方法

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US5936076A (en)	1991-08-29	1999-08-10	Kirin Beer Kabushiki Kaisha	αgalactosylceramide derivatives
CA2230808C (en)	1996-07-03	2006-08-15	Japan Energy Corporation	A novel purine derivative
CN1222293C (zh)	1997-04-10	2005-10-12	麒麟麦酒株式会社	含有α－糖基神经酰胺的NKT细胞活化剂
TW572758B (en)	1997-12-22	2004-01-21	Sumitomo Pharma	Type 2 helper T cell-selective immune response inhibitors comprising purine derivatives
AU4545799A (en)	1998-06-10	1999-12-30	Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The	Beta2 microglobulin fusion proteins and high affinity variants
CN1561389A (zh)	2001-07-25	2005-01-05	纽约大学	糖基神经酰胺作为用于抗传染病和癌症的疫苗的佐剂的用途
WO2003105769A2 (en)	2002-06-13	2003-12-24	New York University	Synthetic c-glycolipid and its use for treating cancer infectious diseases and autoimmune diseases
US20060116331A1 (en)	2002-09-27	2006-06-01	Biomira, Inc.	Glycosylceramide analogues
US9809654B2 (en)	2002-09-27	2017-11-07	Vaccinex, Inc.	Targeted CD1d molecules
EP1619199B1 (en)	2003-02-14	2013-12-18	Japan as represented by President of National Center of Neurology and Psychiatry Ministry of Health	Glycolipid derivatives, process for production of the same, intermediates for synthesis thereof, and process for production of the intermediates
GB0314682D0 (en)	2003-06-24	2003-07-30	Isis Innovation	Materials and methods relating to the modulation of T cell response to soluble antigen
JP2005089334A (ja)	2003-09-12	2005-04-07	Sumitomo Pharmaceut Co Ltd	８−ヒドロキシアデニン化合物
US7771726B2 (en)	2003-10-08	2010-08-10	New York University	Use of synthetic glycolipids as universal adjuvants for vaccines against cancer and infectious diseases
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NZ553320A (en) *	2004-08-27	2011-02-25	Einstein Coll Med	Ceramide derivatives as modulators of immunity and autoimmunity
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WO2006071848A2 (en)	2004-12-28	2006-07-06	The Rockefeller University	Glycolipids and analogues thereof as antigens for nk t cells
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EP2112930B1 (en) *	2007-02-21	2017-01-11	Vaccinex, Inc.	Modulation of nkt cell activity with antigen-loaded cdid molecules
CN102325875B (zh) *	2009-01-08	2018-04-10	阿尔伯爱因斯坦医学有限公司	具有细胞壁结合神经酰胺类糖脂的细菌疫苗及其应用

2014
- 2014-02-07 KR KR1020157024435A patent/KR102167438B1/ko active IP Right Grant
- 2014-02-07 CN CN201480019636.9A patent/CN105339379B/zh not_active Expired - Fee Related
- 2014-02-07 CA CA2900524A patent/CA2900524A1/en not_active Abandoned
- 2014-02-07 WO PCT/US2014/015286 patent/WO2014124245A1/en active Application Filing
- 2014-02-07 EP EP14706210.3A patent/EP2953957B1/en active Active
- 2014-02-07 DK DK14706210.3T patent/DK2953957T3/da active
- 2014-02-07 JP JP2015557115A patent/JP6487854B2/ja not_active Expired - Fee Related
- 2014-02-07 NZ NZ710949A patent/NZ710949A/en not_active IP Right Cessation
- 2014-02-07 AU AU2014214770A patent/AU2014214770B2/en not_active Ceased
- 2014-02-07 ES ES14706210T patent/ES2730649T3/es active Active

Also Published As

Publication number	Publication date
WO2014124245A1 (en)	2014-08-14
AU2014214770B2 (en)	2018-09-06
EP2953957B1 (en)	2019-04-10
ES2730649T3 (es)	2019-11-12
EP2953957A1 (en)	2015-12-16
CN105339379B (zh)	2019-11-26
CN105339379A (zh)	2016-02-17
CA2900524A1 (en)	2014-08-14
JP6487854B2 (ja)	2019-03-20
KR102167438B1 (ko)	2020-10-19
AU2014214770A1 (en)	2015-08-27
NZ710949A (en)	2020-02-28
JP2016509013A (ja)	2016-03-24
KR20150119019A (ko)	2015-10-23

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