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DK2828396T3 - Fremgangsmåde til fremstillingen af g-csf - Google Patents

Fremgangsmåde til fremstillingen af g-csf Download PDF

Info

Publication number
DK2828396T3
DK2828396T3 DK13709469.4T DK13709469T DK2828396T3 DK 2828396 T3 DK2828396 T3 DK 2828396T3 DK 13709469 T DK13709469 T DK 13709469T DK 2828396 T3 DK2828396 T3 DK 2828396T3
Authority
DK
Denmark
Prior art keywords
csf
procedure
preparation
Prior art date
Application number
DK13709469.4T
Other languages
English (en)
Inventor
Katalin Olasz
Ferenc Felföldi
Jozsef Kozma
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Application granted granted Critical
Publication of DK2828396T3 publication Critical patent/DK2828396T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
DK13709469.4T 2012-03-19 2013-03-18 Fremgangsmåde til fremstillingen af g-csf DK2828396T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU1200171A HUP1200171A1 (hu) 2012-03-19 2012-03-19 Módszerek polipeptidek elõállítására
PCT/EP2013/055529 WO2013068602A2 (en) 2012-03-19 2013-03-18 Method for the production of polypeptides

Publications (1)

Publication Number Publication Date
DK2828396T3 true DK2828396T3 (da) 2019-05-27

Family

ID=89990648

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13709469.4T DK2828396T3 (da) 2012-03-19 2013-03-18 Fremgangsmåde til fremstillingen af g-csf

Country Status (15)

Country Link
US (1) US9416164B2 (da)
EP (2) EP2828396B1 (da)
JP (1) JP6154885B2 (da)
KR (1) KR101949556B1 (da)
CN (1) CN104603280A (da)
CA (1) CA2867794C (da)
DK (1) DK2828396T3 (da)
ES (1) ES2732374T3 (da)
HR (1) HRP20190846T1 (da)
HU (2) HUP1200171A1 (da)
LT (1) LT2828396T (da)
PL (1) PL2828396T3 (da)
SI (1) SI2828396T1 (da)
TR (1) TR201907221T4 (da)
WO (1) WO2013068602A2 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP1200171A1 (hu) 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására
HUP1200172A2 (en) 2012-03-19 2013-10-28 Richter Gedeon Nyrt Methods for refolding g-csf from inclusion bodies
US10435732B2 (en) 2014-06-09 2019-10-08 Kaneka Corporation Method for producing recombinant proteins using recombinant brevibacillus
SG11202107201YA (en) * 2018-12-28 2021-07-29 Coherus Biosciences Inc Process for producing, isolating, and purifying modified recombinant proteins
WO2020234742A1 (en) * 2019-05-20 2020-11-26 Lupin Limited Granulocyte colony stimulating factor purification

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61227526A (ja) 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
US4810643A (en) 1985-08-23 1989-03-07 Kirin- Amgen Inc. Production of pluripotent granulocyte colony-stimulating factor
DE3537708A1 (de) 1985-10-23 1987-04-23 Boehringer Mannheim Gmbh Verfahren zur aktivierung von t-pa nach expression in prokaryonten
JPH0618780B2 (ja) * 1986-01-22 1994-03-16 中外製薬株式会社 骨髄性白血病抑制剤
US5714581A (en) 1986-12-23 1998-02-03 Kyowa Hakko Kogyo Co., Ltd. Polypeptide derivatives of human granulocyte colony stimulating factor
JP2796388B2 (ja) 1988-05-13 1998-09-10 アムジエン・インコーポレーテツド G−csfの精製方法
DE3835350A1 (de) 1988-10-17 1990-04-19 Boehringer Mannheim Gmbh Aktivierung von gentechnologisch hergestellten, in prokaryonten exprimierten antikoerpern
WO1990006952A1 (en) 1988-12-22 1990-06-28 Kirin-Amgen, Inc. Chemically modified granulocyte colony stimulating factor
US5055555A (en) 1989-01-05 1991-10-08 Helmut Sassenfeld Purification of G-CSF
FR2669646A1 (fr) 1990-11-23 1992-05-29 Lorraine Laminage Procede de traitement d'un effluent aqueux issu d'un procede d'electrozingage, ainsi que procede et installation en comportant application.
DE4114575C1 (da) 1991-05-04 1992-05-14 Fa. Carl Freudenberg, 6940 Weinheim, De
KR100241257B1 (ko) 1997-05-22 2000-02-01 한승수 인체 과립구 콜로니 자극 인자 활성물질 및 그것의 제조방법
ATE349460T1 (de) 1998-07-09 2007-01-15 Barofold Inc Rückfaltung von protein-aggregaten und einschlussteilchen durch hohen druck
FR2796071B1 (fr) 1999-07-08 2001-09-07 Hoechst Marion Roussel Inc Procede de purification de facteur de stimulation de colonies de granulocytes
EP1284987B1 (en) 2000-05-16 2007-07-18 Bolder Biotechnology, Inc. Methods for refolding proteins containing free cysteine residues
SI21102A (sl) 2001-12-19 2003-06-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Postopek za izolacijo biološko aktivnega granulocitne kolonije stimulirajočega dejavnika
AU2002345829A1 (en) 2002-06-24 2004-01-06 Dr. Reddy's Laboratories Ltd. Process for preparing g-csf
SI21273A (sl) 2002-07-31 2004-02-29 LEK farmacevtska dru�ba d.d. Priprava inkluzijskih teles z visokim deležem pravilno zvitega prekurzorja heterolognega proteina
KR100484653B1 (ko) * 2004-05-06 2005-04-20 주식회사 대웅 원핵세포에서 활성형의 가용성 단백질을 제조하는 방법 및 이를 위한 폴리시스트론 벡터
DE102004041639A1 (de) 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies
US20080171857A1 (en) 2005-03-17 2008-07-17 Uma Devi Komath Process for the Purification of Recombinant Granulocyte-Colony Stimulating Factor
KR100694994B1 (ko) 2005-06-13 2007-03-14 씨제이 주식회사 사람 과립구 콜로니 형성인자 동종체
GB0605684D0 (en) 2006-03-21 2006-05-03 Sicor Biotech Uab Method For Purifying Granulocyte-Colony Stimulating Factor
WO2008009366A1 (en) 2006-07-21 2008-01-24 Sony Service Centre (Europe) N.V. System having plurality of hardware blocks and method of operating the same
WO2008096370A2 (en) 2007-02-05 2008-08-14 Natco Pharma Limited An efficient and novel purification method of recombinant hg-csf
WO2008096368A2 (en) * 2007-02-05 2008-08-14 Natco Pharma Limited A novel process for production of recombinant human g-csf
CN101358196A (zh) 2008-08-29 2009-02-04 浙江理工大学 利用家蚕后部丝腺体外表达系统合成蛋白质的方法
CN101691560B (zh) 2008-12-19 2011-08-31 华南理工大学 大肠杆菌及其可溶性表达转谷氨酰胺酶酶原的方法
EP2443135A1 (en) 2009-06-16 2012-04-25 Lupin Ltd. Process for purification of recombinant human granulocyte colony stimulating factor
HUP1200172A2 (en) 2012-03-19 2013-10-28 Richter Gedeon Nyrt Methods for refolding g-csf from inclusion bodies
HUP1200171A1 (hu) 2012-03-19 2013-09-30 Richter Gedeon Nyrt Módszerek polipeptidek elõállítására

Also Published As

Publication number Publication date
JP2015514398A (ja) 2015-05-21
ES2732374T3 (es) 2019-11-22
HRP20190846T1 (hr) 2019-08-09
US9416164B2 (en) 2016-08-16
CA2867794A1 (en) 2013-05-16
LT2828396T (lt) 2019-05-27
CN104603280A (zh) 2015-05-06
WO2013068602A2 (en) 2013-05-16
EP2828396A2 (en) 2015-01-28
EP2828396B1 (en) 2019-04-24
CA2867794C (en) 2020-06-09
US20150044721A1 (en) 2015-02-12
WO2013068602A3 (en) 2013-08-01
HUP1200171A1 (hu) 2013-09-30
EP3517621A1 (en) 2019-07-31
TR201907221T4 (tr) 2019-06-21
HUE045310T2 (hu) 2019-12-30
PL2828396T3 (pl) 2019-08-30
KR20140144705A (ko) 2014-12-19
JP6154885B2 (ja) 2017-06-28
KR101949556B1 (ko) 2019-02-18
SI2828396T1 (sl) 2019-06-28

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