DK2819667T3 - Retinalderivater til anvendelse til forbedring af synsfunktionen - Google Patents
Retinalderivater til anvendelse til forbedring af synsfunktionen Download PDFInfo
- Publication number
- DK2819667T3 DK2819667T3 DK13760943.4T DK13760943T DK2819667T3 DK 2819667 T3 DK2819667 T3 DK 2819667T3 DK 13760943 T DK13760943 T DK 13760943T DK 2819667 T3 DK2819667 T3 DK 2819667T3
- Authority
- DK
- Denmark
- Prior art keywords
- improve
- vision function
- retinal derivatives
- retinal
- derivatives
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/11—Aldehydes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Ophthalmology & Optometry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261605729P | 2012-03-01 | 2012-03-01 | |
US201261642212P | 2012-05-03 | 2012-05-03 | |
US201261644360P | 2012-05-08 | 2012-05-08 | |
PCT/CA2013/050155 WO2013134867A1 (en) | 2012-03-01 | 2013-03-01 | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2819667T3 true DK2819667T3 (da) | 2020-03-30 |
Family
ID=49160185
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13760943.4T DK2819667T3 (da) | 2012-03-01 | 2013-03-01 | Retinalderivater til anvendelse til forbedring af synsfunktionen |
Country Status (17)
Country | Link |
---|---|
US (2) | US20160296478A1 (da) |
EP (1) | EP2819667B8 (da) |
JP (3) | JP6576636B2 (da) |
KR (1) | KR102133608B1 (da) |
CN (2) | CN109248163A (da) |
AU (3) | AU2013232697B2 (da) |
BR (1) | BR112014021602A2 (da) |
CA (1) | CA2865935C (da) |
DK (1) | DK2819667T3 (da) |
ES (1) | ES2780357T3 (da) |
HK (1) | HK1205469A1 (da) |
IL (1) | IL234306B (da) |
MX (1) | MX370928B (da) |
NZ (1) | NZ629267A (da) |
PT (1) | PT2819667T (da) |
RU (1) | RU2635536C2 (da) |
WO (1) | WO2013134867A1 (da) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2622763C2 (ru) | 2010-04-19 | 2017-06-19 | Новелион Терапьютикс Инк. | Лечебная схема и способы лечения или уменьшения нарушений зрения, связанных с дефицитом эндогенных ретиноидов |
CN109248163A (zh) | 2012-03-01 | 2019-01-22 | 诺维利昂治疗股份有限公司 | 用于在与内源性维甲酸类缺乏相关的视觉障碍中改善视觉功能的治疗方案和方法 |
WO2015164419A1 (en) * | 2014-04-22 | 2015-10-29 | Acucela Inc. | Pupillometric assessment of retinal pharmacodynamics and responses therefrom |
US20180170867A1 (en) * | 2015-05-08 | 2018-06-21 | University Of Debrecen | Stereoselective synthesis of 9-cis.13,14-dihydroretinoic acid and its ethyl esters |
US12029715B2 (en) * | 2015-05-08 | 2024-07-09 | University Of Debrecen | Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereof |
AU2017359593B2 (en) | 2016-11-17 | 2022-03-17 | Universidade De Vigo | Precursor compounds for providing retinoids of the vitamin A5 pathway and uses thereof |
RU186184U1 (ru) * | 2018-06-06 | 2019-01-11 | Федеральное государственное бюджетное учреждение "33 Центральный научно-исследовательский испытательный институт" Министерства обороны Российской Федерации | Устройство для оценки углов обзора и поля зрения испытателей в противогазе |
WO2024110625A1 (en) | 2022-11-24 | 2024-05-30 | Universität Bern | Cralbp based therapeutics for retinal disorders |
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US3196078A (en) | 1962-01-30 | 1965-07-20 | Ortho Pharma Corp | Process for combating retinits pigmentosa |
US3517067A (en) | 1964-02-11 | 1970-06-23 | Eastman Kodak Co | Syntheses of quaternary phosphonium salts |
DE2300107C2 (de) | 1973-01-03 | 1982-03-11 | Basf Ag, 6700 Ludwigshafen | Vitamin A-Säureanilid-4-carbonsäureäthylester, Verfahren zu seiner Herstellung und diesen enthaltende Zubereitungen |
CH590222A5 (da) | 1973-08-21 | 1977-07-29 | Hoffmann La Roche | |
US4022913A (en) | 1973-09-13 | 1977-05-10 | Hoffmann-La Roche Inc. | High potency vitamin A compositions |
DE2456959A1 (de) | 1974-12-03 | 1976-06-16 | Basf Ag | 4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen |
CA1198859A (en) | 1982-04-21 | 1986-01-07 | Chester L. O'neal | Disposable toothbrush with cap |
US4532133A (en) | 1983-05-24 | 1985-07-30 | Basf Wyandotte Corporation | Low temperature stable, emulsifiable vitamin A concentrates |
CA1282326C (en) | 1984-12-14 | 1991-04-02 | Paul J. Jarosz | Pharmaceutical composition containing 13-cis vitamin a acid as the active ingredient |
JPS61275266A (ja) | 1985-05-28 | 1986-12-05 | Taisho Pharmaceut Co Ltd | レチノイド誘導体 |
CZ282548B6 (cs) | 1992-01-22 | 1997-08-13 | F. Hoffmann-La Roche Ag | Farmaceutický přípravek |
US5310764A (en) | 1992-05-08 | 1994-05-10 | Steven Baranowitz | Treatment of age related macular degeneration with beta-carotene |
JPH06340525A (ja) | 1993-06-02 | 1994-12-13 | Lion Corp | 安定な低眼刺激性ビタミンa類可溶化点眼剤 |
EP0754046A1 (en) | 1994-04-04 | 1997-01-22 | FREEMAN, William R. | Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure |
RU2106843C1 (ru) | 1994-06-29 | 1998-03-20 | Красноярская государственная медицинская академия | Способ лечения близорукости |
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US5489611A (en) | 1995-02-10 | 1996-02-06 | Warner-Lambert Company | Method for lowering plasma levels of lipoprotein (a) |
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US6391924B1 (en) | 1997-12-10 | 2002-05-21 | Hampar Karageozian | Taurine derivatives useable in the treatment of ophthalmic disorders |
US6552009B2 (en) | 1998-07-16 | 2003-04-22 | Gentrix Llc | Compositions and methods of treating abnormal cell proliferation |
US6267985B1 (en) | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
US6372463B1 (en) | 1999-05-06 | 2002-04-16 | The President & Fellows Of Harvard College | Mutations in nucleic acid molecules encoding 11-CIS retinol dehydrogenase, the mutated proteins, and uses thereof |
US6300328B1 (en) | 1999-08-06 | 2001-10-09 | Alcon Universal Ltd. | Selective inhibitors of adenosine monophosphate deaminase for the treatment of optic nerve and retinal damage |
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CN101969938A (zh) | 2008-02-11 | 2011-02-09 | 华盛顿大学 | 治疗和预防年龄相关视网膜功能障碍的方法 |
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FR2955459B1 (fr) * | 2010-01-28 | 2013-11-22 | Polaris | Composition huileuse riche en monoglycerides de dha |
RU2622763C2 (ru) * | 2010-04-19 | 2017-06-19 | Новелион Терапьютикс Инк. | Лечебная схема и способы лечения или уменьшения нарушений зрения, связанных с дефицитом эндогенных ретиноидов |
CN109248163A (zh) | 2012-03-01 | 2019-01-22 | 诺维利昂治疗股份有限公司 | 用于在与内源性维甲酸类缺乏相关的视觉障碍中改善视觉功能的治疗方案和方法 |
US20150038582A1 (en) | 2012-03-01 | 2015-02-05 | Qlt Inc. | Therapeutic regimens and methods for improving visual function in visual disorders associated with an endogenous retinoid deficiency |
-
2013
- 2013-03-01 CN CN201811054761.XA patent/CN109248163A/zh active Pending
- 2013-03-01 AU AU2013232697A patent/AU2013232697B2/en active Active
- 2013-03-01 EP EP13760943.4A patent/EP2819667B8/en active Active
- 2013-03-01 RU RU2014139666A patent/RU2635536C2/ru active
- 2013-03-01 BR BR112014021602A patent/BR112014021602A2/pt not_active Application Discontinuation
- 2013-03-01 CN CN201380022484.3A patent/CN104470511A/zh active Pending
- 2013-03-01 WO PCT/CA2013/050155 patent/WO2013134867A1/en active Application Filing
- 2013-03-01 MX MX2014010457A patent/MX370928B/es active IP Right Grant
- 2013-03-01 DK DK13760943.4T patent/DK2819667T3/da active
- 2013-03-01 KR KR1020147027749A patent/KR102133608B1/ko active IP Right Grant
- 2013-03-01 PT PT137609434T patent/PT2819667T/pt unknown
- 2013-03-01 NZ NZ629267A patent/NZ629267A/en not_active IP Right Cessation
- 2013-03-01 ES ES13760943T patent/ES2780357T3/es active Active
- 2013-03-01 CA CA2865935A patent/CA2865935C/en active Active
- 2013-03-01 JP JP2014559050A patent/JP6576636B2/ja active Active
-
2014
- 2014-08-26 IL IL234306A patent/IL234306B/en unknown
-
2015
- 2015-06-29 HK HK15106135.6A patent/HK1205469A1/xx not_active IP Right Cessation
-
2016
- 2016-04-11 US US15/096,048 patent/US20160296478A1/en not_active Abandoned
-
2017
- 2017-08-15 JP JP2017156807A patent/JP2017197588A/ja active Pending
-
2018
- 2018-01-18 AU AU2018200415A patent/AU2018200415B2/en not_active Expired - Fee Related
- 2018-06-11 US US16/005,155 patent/US10828267B2/en active Active
-
2019
- 2019-12-20 AU AU2019283995A patent/AU2019283995B2/en not_active Ceased
-
2020
- 2020-02-10 JP JP2020020391A patent/JP2020073597A/ja active Pending
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