DK2895607T3 - Dobbeltstrengede oligonukleotidmolekyler til ddit4 og fremgangsmåder til anvendelse deraf - Google Patents
Dobbeltstrengede oligonukleotidmolekyler til ddit4 og fremgangsmåder til anvendelse deraf Download PDFInfo
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- DK2895607T3 DK2895607T3 DK13773450.5T DK13773450T DK2895607T3 DK 2895607 T3 DK2895607 T3 DK 2895607T3 DK 13773450 T DK13773450 T DK 13773450T DK 2895607 T3 DK2895607 T3 DK 2895607T3
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- Prior art keywords
- ddit4
- string
- double
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- oligonucleotide molecules
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/319—Chemical structure of the backbone linked by 2'-5' linkages, i.e. having a free 3'-position
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/352—Nature of the modification linked to the nucleic acid via a carbon atom
- C12N2310/3521—Methyl
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- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
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- Heart & Thoracic Surgery (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261699884P | 2012-09-12 | 2012-09-12 | |
PCT/US2013/059341 WO2014043289A2 (en) | 2012-09-12 | 2013-09-12 | Double-stranded oligonucleotide molecules to ddit4 and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2895607T3 true DK2895607T3 (da) | 2021-05-25 |
Family
ID=49304313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13773450.5T DK2895607T3 (da) | 2012-09-12 | 2013-09-12 | Dobbeltstrengede oligonukleotidmolekyler til ddit4 og fremgangsmåder til anvendelse deraf |
Country Status (10)
Country | Link |
---|---|
US (3) | US9932578B2 (da) |
EP (1) | EP2895607B1 (da) |
JP (1) | JP6364009B2 (da) |
CN (1) | CN104619844A (da) |
BR (1) | BR112015004747A2 (da) |
CA (1) | CA2880290C (da) |
DK (1) | DK2895607T3 (da) |
ES (1) | ES2872349T3 (da) |
HK (1) | HK1210216A1 (da) |
WO (1) | WO2014043289A2 (da) |
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JP7551056B2 (ja) | 2017-10-05 | 2024-09-17 | ソニーグループ株式会社 | プログラマブルなポリマー薬物 |
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CN111565756A (zh) | 2018-01-12 | 2020-08-21 | 索尼公司 | 包含生物活性化合物的具有刚性间隔基团的聚合物 |
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-
2013
- 2013-09-12 JP JP2015531340A patent/JP6364009B2/ja not_active Expired - Fee Related
- 2013-09-12 EP EP13773450.5A patent/EP2895607B1/en active Active
- 2013-09-12 WO PCT/US2013/059341 patent/WO2014043289A2/en active Application Filing
- 2013-09-12 US US14/421,845 patent/US9932578B2/en not_active Expired - Fee Related
- 2013-09-12 BR BR112015004747A patent/BR112015004747A2/pt not_active IP Right Cessation
- 2013-09-12 DK DK13773450.5T patent/DK2895607T3/da active
- 2013-09-12 CN CN201380047225.6A patent/CN104619844A/zh active Pending
- 2013-09-12 ES ES13773450T patent/ES2872349T3/es active Active
- 2013-09-12 US US14/426,513 patent/US9611474B2/en active Active
- 2013-09-12 CA CA2880290A patent/CA2880290C/en not_active Expired - Fee Related
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2015
- 2015-11-05 HK HK15110939.6A patent/HK1210216A1/xx unknown
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2017
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Also Published As
Publication number | Publication date |
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US9611474B2 (en) | 2017-04-04 |
CA2880290C (en) | 2020-10-27 |
BR112015004747A2 (pt) | 2017-11-21 |
US9932578B2 (en) | 2018-04-03 |
WO2014043289A2 (en) | 2014-03-20 |
EP2895607B1 (en) | 2021-05-05 |
EP2895607A2 (en) | 2015-07-22 |
CN104619844A (zh) | 2015-05-13 |
HK1210216A1 (en) | 2016-04-15 |
CA2880290A1 (en) | 2014-03-20 |
JP6364009B2 (ja) | 2018-07-25 |
US20180044671A9 (en) | 2018-02-15 |
US10421962B2 (en) | 2019-09-24 |
US20150267194A1 (en) | 2015-09-24 |
US20180010125A1 (en) | 2018-01-11 |
WO2014043289A3 (en) | 2014-06-05 |
US20150203845A1 (en) | 2015-07-23 |
JP2015535174A (ja) | 2015-12-10 |
ES2872349T3 (es) | 2021-11-02 |
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