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DK2849724T3 - Middel til at fremme fødemiddelindtag og fødemiddelretention - Google Patents

Middel til at fremme fødemiddelindtag og fødemiddelretention Download PDF

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Publication number
DK2849724T3
DK2849724T3 DK13724779.7T DK13724779T DK2849724T3 DK 2849724 T3 DK2849724 T3 DK 2849724T3 DK 13724779 T DK13724779 T DK 13724779T DK 2849724 T3 DK2849724 T3 DK 2849724T3
Authority
DK
Denmark
Prior art keywords
local anesthetic
food
esophagus
food intake
stomach
Prior art date
Application number
DK13724779.7T
Other languages
English (en)
Inventor
Christophorus Louis Eduard Broekkamp
Bernardus Wijnand Mathijs Marie Peeters
Original Assignee
Orexa B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orexa B V filed Critical Orexa B V
Application granted granted Critical
Publication of DK2849724T3 publication Critical patent/DK2849724T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Nutrition Science (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Claims (6)

1. Lokalbedøvelsesmiddel til anvendelse i en fremgangsmåde til behandling af (i) anoreksi, (ii) kakeksi, (iii) sarkopeni og (iv) postoperative komplikationer i fødemiddelforarbejdning efter operation på tarmkanalen eller efter kejsersnit, omfattende at benytte en tilstrækkelig dosis af lokalbedøvelsesmidlet til en overflade af svælget, spiserøret, og/eller maven for at fremme fødemiddelindtag og fødemiddelretention hos et pattedyr, lokalbedøvelsesmidlet er lidocain eller ropivacain.
2. Lokalbedøvelsesmiddel til anvendelse i en fremgangsmåde til behandling af (i) anoreksi, (ii) kakeksi, (iii) sarkopeni og (iv) postoperative komplikationer i fødemiddelforarbejdning efter operation på tarmkanalen eller efter kejsersnit, omfattende at benytte en tilstrækkelig dosis af lokalbedøvelsesmidlet i svælghulrummet, spiserøret, og/eller maven før eller under eller efter spisning, for at fremme fødemiddelindtag og fødemiddelretention hos et pattedyr, lokalbedøvelsesmidlet er lidocain eller ropivacain.
3. Lokalbedøvelsesmiddel til anvendelse ifølge et hvilket som helst af krav 1-2, k e n detegnet ved, at lokalbedøvelsesmidlet benyttes på en overflade af spiserøret.
4. Lokalbedøvelsesmiddel til anvendelse ifølge krav 1, kendetegnet ved, at lokalbedøvelsesmidlet benyttes på en overflade af maven.
5. Lokalbedøvelsesmiddel til anvendelse ifølge et hvilket som helst af krav 1-4, k e n detegnet ved, at lægemidlet er formuleret i en opløsning eller suspension i et fremføringsmiddel, som fremmer retention af formuleringen med et slimhindepitel fra et pattedyr.
6. Lokalbedøvelsesmiddel til anvendelse ifølge krav 5, kendetegnet ved, at lokalbedøvelsesmidlet er opløst eller opslæmmet i en opløsning af alginat.
DK13724779.7T 2012-05-16 2013-05-15 Middel til at fremme fødemiddelindtag og fødemiddelretention DK2849724T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12075046 2012-05-16
PCT/EP2013/060013 WO2013171252A1 (en) 2012-05-16 2013-05-15 Means to facilitate food intake and food retention

Publications (1)

Publication Number Publication Date
DK2849724T3 true DK2849724T3 (da) 2018-10-15

Family

ID=48485144

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13724779.7T DK2849724T3 (da) 2012-05-16 2013-05-15 Middel til at fremme fødemiddelindtag og fødemiddelretention

Country Status (7)

Country Link
US (2) US10828272B2 (da)
EP (2) EP3409271B1 (da)
DK (1) DK2849724T3 (da)
ES (1) ES2689293T3 (da)
PL (1) PL2849724T3 (da)
PT (1) PT2849724T (da)
WO (1) WO2013171252A1 (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2849724T3 (da) * 2012-05-16 2018-10-15 Orexa B V Middel til at fremme fødemiddelindtag og fødemiddelretention
NL2029094B1 (en) 2021-09-01 2023-03-17 Orexa B V Composition for increasing feed intake
MX2024006405A (es) 2021-11-25 2024-06-05 Orexa B V Unidad de dosificacion oral gastrorretentiva que contiene un anestesico local.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5417671A (en) * 1990-05-23 1995-05-23 Jackson; Richard R. Medical devices having local anesthetic effect and methods of their manufacture
US6103257A (en) * 1998-07-17 2000-08-15 Num-Pop, Inc. System for delivering pharmaceuticals to the buccal mucosa
US6299902B1 (en) * 1999-05-19 2001-10-09 The University Of Georgia Research Foundation, Inc. Enhanced transdermal anesthesia of local anesthetic agents
DK1809329T3 (da) * 2004-09-17 2012-04-02 Durect Corp Vedvarende lokalanæstesisammensætning indeholdende saib
US20070020195A1 (en) * 2005-06-08 2007-01-25 Greenway Frank L Iii Nasally administered appetite suppressants
US20080021068A1 (en) * 2006-07-24 2008-01-24 Akorn, Inc. Aqueous gel formulation and method for inducing topical anesthesia
JP2008094743A (ja) * 2006-10-10 2008-04-24 Tohoku Techno Arch Co Ltd 摂食・嚥下改善食品
ES2605814T3 (es) * 2011-04-29 2017-03-16 Moberg Pharma Ab Composiciones farmacéuticas que comprenden un anestésico local tal como bupivacaína para administración local en la boca o la garganta
DK2849724T3 (da) * 2012-05-16 2018-10-15 Orexa B V Middel til at fremme fødemiddelindtag og fødemiddelretention

Also Published As

Publication number Publication date
WO2013171252A1 (en) 2013-11-21
EP3409271B1 (en) 2024-07-24
EP2849724B1 (en) 2018-07-11
PT2849724T (pt) 2018-10-30
US20150133502A1 (en) 2015-05-14
EP3409271C0 (en) 2024-07-24
EP2849724A1 (en) 2015-03-25
EP3409271A1 (en) 2018-12-05
US11925610B2 (en) 2024-03-12
ES2689293T3 (es) 2018-11-13
EP2849724B8 (en) 2018-08-29
US20210008016A1 (en) 2021-01-14
PL2849724T3 (pl) 2019-01-31
US10828272B2 (en) 2020-11-10

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