DK2654785T3 - Forøget immunrespons hos kvægracer - Google Patents
Forøget immunrespons hos kvægracer Download PDFInfo
- Publication number
- DK2654785T3 DK2654785T3 DK11804675.4T DK11804675T DK2654785T3 DK 2654785 T3 DK2654785 T3 DK 2654785T3 DK 11804675 T DK11804675 T DK 11804675T DK 2654785 T3 DK2654785 T3 DK 2654785T3
- Authority
- DK
- Denmark
- Prior art keywords
- immune response
- increased immune
- cattle breeds
- breeds
- cattle
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/711—Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dispersion Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201061426255P | 2010-12-22 | 2010-12-22 | |
PCT/EP2011/073414 WO2012084951A1 (en) | 2010-12-22 | 2011-12-20 | Enhanced immune response in bovine species |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2654785T3 true DK2654785T3 (da) | 2019-06-24 |
Family
ID=45444595
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK11804675.4T DK2654785T3 (da) | 2010-12-22 | 2011-12-20 | Forøget immunrespons hos kvægracer |
Country Status (34)
Country | Link |
---|---|
US (3) | US20130295167A1 (da) |
EP (1) | EP2654785B1 (da) |
JP (2) | JP6058550B2 (da) |
KR (1) | KR101940826B1 (da) |
CN (2) | CN108379576A (da) |
AR (1) | AR084510A1 (da) |
AU (1) | AU2011347464B2 (da) |
BR (1) | BR112013016231B1 (da) |
CA (1) | CA2822359C (da) |
CL (1) | CL2013001833A1 (da) |
CO (1) | CO6761354A2 (da) |
CR (1) | CR20130312A (da) |
DK (1) | DK2654785T3 (da) |
DO (1) | DOP2013000149A (da) |
EC (1) | ECSP13012709A (da) |
ES (1) | ES2722204T3 (da) |
GT (1) | GT201300168A (da) |
HK (1) | HK1259341A1 (da) |
HR (1) | HRP20190779T1 (da) |
HU (1) | HUE043473T4 (da) |
IL (1) | IL226733B (da) |
LT (1) | LT2654785T (da) |
MX (1) | MX345854B (da) |
MY (1) | MY167159A (da) |
NZ (1) | NZ612285A (da) |
PL (1) | PL2654785T3 (da) |
PT (1) | PT2654785T (da) |
RU (1) | RU2606855C2 (da) |
SI (1) | SI2654785T1 (da) |
TR (1) | TR201906323T4 (da) |
TW (1) | TWI587877B (da) |
UA (1) | UA118537C2 (da) |
UY (1) | UY33821A (da) |
WO (1) | WO2012084951A1 (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
UA118537C2 (uk) | 2010-12-22 | 2019-02-11 | Байєр Інтеллектуал Проперті Гмбх | Композиція імуномодулятора для лікування респіратоного захворювання у великої рогатої худоби |
JO3733B1 (ar) | 2011-04-05 | 2021-01-31 | Bayer Ip Gmbh | استخدام 3,2-دايهيدروايميدازو[1, 2 -c]كوينازولينات مستبدلة |
RU2740492C2 (ru) * | 2014-02-28 | 2021-01-14 | Байер Энимэл Хельс ГмбХ | Иммуностимулирующие плазмиды |
CN104825393B (zh) * | 2015-01-16 | 2017-11-10 | 艾美科健(中国)生物医药有限公司 | 一种硫酸头孢喹肟肺靶向脂质体制剂及其制备方法 |
RU2018102915A (ru) * | 2015-06-26 | 2019-07-29 | Байер Энимэл Хельс ГмбХ | Способы модуляции контрольных молекул цитозольной днк |
KR20180035860A (ko) * | 2015-07-31 | 2018-04-06 | 바이엘 애니멀 헬스 게엠베하 | 수생 종에서의 향상된 면역 반응 |
CA2993883A1 (en) | 2015-07-31 | 2017-02-09 | Bayer Animal Health Gmbh | Enhanced immune response in porcine species |
BR112019001599A2 (pt) * | 2016-07-26 | 2019-10-01 | Bayer Animal Health Gmbh | fertilidade aumentada em espécies bovinas |
KR102069670B1 (ko) * | 2017-03-02 | 2020-01-23 | 단디바이오사이언스 주식회사 | 면역활성물질을 포함하는 다중도메인캡슐, 이의 제조방법, 및 이를 포함하는 면역조절 조성물 |
CA3085661A1 (en) * | 2017-12-15 | 2019-06-20 | Bayer Animal Health Gmbh | Immunostimulatory oligonucleotides |
CN108812546A (zh) * | 2018-09-07 | 2018-11-16 | 四川省草原科学研究院 | 适于青藏高原地区牦牛运输减少应激的药物及使用方法 |
CN109646435B (zh) * | 2019-01-11 | 2021-08-03 | 山东省农业科学院奶牛研究中心 | 厄他培南钠在制备防治牛传染性鼻气管炎药物中的应用 |
WO2020194735A1 (ja) | 2019-03-28 | 2020-10-01 | 日本電気株式会社 | 情報処理装置、サーバ割当装置、方法、及びコンピュータ可読媒体 |
CN114480663A (zh) * | 2021-11-15 | 2022-05-13 | 贵州省畜牧兽医研究所 | 用于检测猪源差异脲原体的引物对、试剂盒及检测方法 |
Family Cites Families (32)
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US3854480A (en) | 1969-04-01 | 1974-12-17 | Alza Corp | Drug-delivery system |
US4675189A (en) | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
US4452775A (en) | 1982-12-03 | 1984-06-05 | Syntex (U.S.A.) Inc. | Cholesterol matrix delivery system for sustained release of macromolecules |
US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5407686A (en) | 1991-11-27 | 1995-04-18 | Sidmak Laboratories, Inc. | Sustained release composition for oral administration of active ingredient |
US5427791A (en) | 1992-08-05 | 1995-06-27 | Regents Of The University Of Minnesota | Embryonal vaccine against Newcastle disease |
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6429199B1 (en) | 1994-07-15 | 2002-08-06 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules for activating dendritic cells |
US6239116B1 (en) | 1994-07-15 | 2001-05-29 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US5830878A (en) * | 1995-06-07 | 1998-11-03 | Megabios Corporation | Cationic lipid: DNA complexes for gene targeting |
US5736152A (en) | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
US6048535A (en) | 1997-06-12 | 2000-04-11 | Regents Of The University Of Minnesota | Multivalent in ovo avian vaccine |
US20030022854A1 (en) * | 1998-06-25 | 2003-01-30 | Dow Steven W. | Vaccines using nucleic acid-lipid complexes |
US6693086B1 (en) | 1998-06-25 | 2004-02-17 | National Jewish Medical And Research Center | Systemic immune activation method using nucleic acid-lipid complexes |
US20040247662A1 (en) * | 1998-06-25 | 2004-12-09 | Dow Steven W. | Systemic immune activation method using nucleic acid-lipid complexes |
JP4800485B2 (ja) | 1999-03-26 | 2011-10-26 | バイカル インコーポレイテッド | ポリヌクレオチドベースのワクチンに対する免疫応答を増強するためのアジュバント組成物および方法 |
RU2158587C1 (ru) * | 1999-05-11 | 2000-11-10 | Ставропольское научно-производственное объединение "Пульс" | Антибактериальное средство для лечения заболеваний сельскохозяйственных животных и птиц, способ профилактики и лечения цыплят при заболеваниях бактериальной этиологии, способ лечения респираторной болезни телят бактериальной этиологии, способ профилактики туберкулеза у крупного рогатого скота |
US20040002472A1 (en) * | 2000-01-21 | 2004-01-01 | Audonnet Jean-Christophe Francis | Vaccination or immunization using a prime-boost regimen |
PE20020572A1 (es) * | 2000-12-06 | 2002-07-31 | Centro Inmunologia Molecular | Preparaciones para potenciar la inmunogenicidad de antigenos poco inmunogenicos |
OA13092A (en) | 2001-04-24 | 2006-11-10 | Innogenetics Nv | Constructs and methods for expression of recombinant HCV envelope proteins. |
CA2452666A1 (en) * | 2001-07-02 | 2003-01-16 | Pfizer Products Inc. | Mycoplasma hyopneumoniae vaccine and methods for reducing mycoplasma bovis pneumonia in cattle |
CN1764474B (zh) * | 2003-03-26 | 2011-02-02 | 惠氏公司 | 免疫原性组合物及方法 |
MY146351A (en) * | 2003-05-29 | 2012-08-15 | Schering Plough Ltd | Compositions for treating infection in cattle and swine |
AU2004280143A1 (en) * | 2003-10-11 | 2005-04-21 | Tekmira Pharmaceuticals Corporation | Methods and compositions for enhancing innate immunity and antibody dependent cellular cytotoxicity |
US20090068223A1 (en) | 2005-11-15 | 2009-03-12 | Boehringer Ingelheim Vetmedica, Inc. | Combination vaccine comprising an attenuated bovine viral diarrhea virus |
JP2008094763A (ja) * | 2006-10-12 | 2008-04-24 | Takeshi Ogura | 海洋ミネラル成分からなるインターフェロンγ産生増強剤 |
EP2249843A4 (en) * | 2008-02-24 | 2013-05-08 | Us Gov Health & Human Serv | USE OF IMMUNOGENIC COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF PATHOGENIC INFECTIONS |
BRPI0910036B8 (pt) * | 2008-03-25 | 2021-05-25 | Juvaris Biotherapeutics Inc | kit compreendendo um primeiro administrador para via intra-venosa de um complexo de lipídio catiônico-dna (cldc) e um segundo administrador de uma vacina |
NZ591950A (en) * | 2008-10-31 | 2012-12-21 | Boehringer Ingelheim Vetmed | Use of various antigens including antigens from mycoplasma bovis in multivalent vaccine composition |
EP2992899B1 (en) * | 2009-05-14 | 2020-07-01 | Bayer Intellectual Property GmbH | Enhanced immune response in avian species |
UA118537C2 (uk) | 2010-12-22 | 2019-02-11 | Байєр Інтеллектуал Проперті Гмбх | Композиція імуномодулятора для лікування респіратоного захворювання у великої рогатої худоби |
-
2011
- 2011-12-20 UA UAA201308922A patent/UA118537C2/uk unknown
- 2011-12-20 SI SI201131729T patent/SI2654785T1/sl unknown
- 2011-12-20 WO PCT/EP2011/073414 patent/WO2012084951A1/en active Application Filing
- 2011-12-20 CA CA2822359A patent/CA2822359C/en active Active
- 2011-12-20 KR KR1020137018801A patent/KR101940826B1/ko active IP Right Grant
- 2011-12-20 UY UY0001033821A patent/UY33821A/es not_active Application Discontinuation
- 2011-12-20 PT PT11804675T patent/PT2654785T/pt unknown
- 2011-12-20 LT LTEP11804675.4T patent/LT2654785T/lt unknown
- 2011-12-20 CN CN201810200992.0A patent/CN108379576A/zh active Pending
- 2011-12-20 DK DK11804675.4T patent/DK2654785T3/da active
- 2011-12-20 ES ES11804675T patent/ES2722204T3/es active Active
- 2011-12-20 AU AU2011347464A patent/AU2011347464B2/en active Active
- 2011-12-20 NZ NZ612285A patent/NZ612285A/en unknown
- 2011-12-20 JP JP2013545307A patent/JP6058550B2/ja active Active
- 2011-12-20 MY MYPI2013701066A patent/MY167159A/en unknown
- 2011-12-20 BR BR112013016231-7A patent/BR112013016231B1/pt active IP Right Grant
- 2011-12-20 RU RU2013133730A patent/RU2606855C2/ru active
- 2011-12-20 CN CN201180066905.3A patent/CN103501810A/zh active Pending
- 2011-12-20 PL PL11804675T patent/PL2654785T3/pl unknown
- 2011-12-20 EP EP11804675.4A patent/EP2654785B1/en active Active
- 2011-12-20 US US13/995,960 patent/US20130295167A1/en not_active Abandoned
- 2011-12-20 MX MX2013007064A patent/MX345854B/es active IP Right Grant
- 2011-12-20 HU HUE11804675A patent/HUE043473T4/hu unknown
- 2011-12-20 TR TR2019/06323T patent/TR201906323T4/tr unknown
- 2011-12-21 AR ARP110104848A patent/AR084510A1/es unknown
- 2011-12-21 TW TW100147617A patent/TWI587877B/zh active
-
2013
- 2013-06-04 IL IL226733A patent/IL226733B/en active IP Right Grant
- 2013-06-20 CL CL2013001833A patent/CL2013001833A1/es unknown
- 2013-06-21 US US13/923,496 patent/US20140010865A1/en not_active Abandoned
- 2013-06-21 CO CO13148228A patent/CO6761354A2/es not_active Application Discontinuation
- 2013-06-21 GT GT201300168A patent/GT201300168A/es unknown
- 2013-06-21 EC ECSP13012709 patent/ECSP13012709A/es unknown
- 2013-06-21 DO DO2013000149A patent/DOP2013000149A/es unknown
- 2013-06-21 CR CR20130312A patent/CR20130312A/es unknown
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2016
- 2016-09-12 JP JP2016177599A patent/JP2017036290A/ja active Pending
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2018
- 2018-08-08 US US16/058,888 patent/US10751361B2/en active Active
-
2019
- 2019-01-31 HK HK19101707.1A patent/HK1259341A1/zh unknown
- 2019-04-25 HR HRP20190779TT patent/HRP20190779T1/hr unknown
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