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DK240678A - PROCEDURE FOR THE PREPARATION OF DI AND TRIFLUOROMETHYLAMINO ACIDS - Google Patents

PROCEDURE FOR THE PREPARATION OF DI AND TRIFLUOROMETHYLAMINO ACIDS

Info

Publication number
DK240678A
DK240678A DK240678A DK240678A DK240678A DK 240678 A DK240678 A DK 240678A DK 240678 A DK240678 A DK 240678A DK 240678 A DK240678 A DK 240678A DK 240678 A DK240678 A DK 240678A
Authority
DK
Denmark
Prior art keywords
trifluoromethylamino
acids
procedure
preparation
trifluoromethylamino acids
Prior art date
Application number
DK240678A
Other languages
Danish (da)
Inventor
J Kollonitsch
S Marburg
A A Patchett
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK240678A publication Critical patent/DK240678A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78Radicals substituted by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/48Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation involving decarboxylation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/255Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK240678A 1977-06-01 1978-05-31 PROCEDURE FOR THE PREPARATION OF DI AND TRIFLUOROMETHYLAMINO ACIDS DK240678A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80238877A 1977-06-01 1977-06-01

Publications (1)

Publication Number Publication Date
DK240678A true DK240678A (en) 1978-12-02

Family

ID=25183563

Family Applications (1)

Application Number Title Priority Date Filing Date
DK240678A DK240678A (en) 1977-06-01 1978-05-31 PROCEDURE FOR THE PREPARATION OF DI AND TRIFLUOROMETHYLAMINO ACIDS

Country Status (6)

Country Link
EP (1) EP0000034B1 (en)
JP (1) JPS5416437A (en)
DE (1) DE2862407D1 (en)
DK (1) DK240678A (en)
IE (1) IE47542B1 (en)
IT (1) IT7849635A0 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
AU3872678A (en) * 1977-09-01 1980-02-14 Merrell Toraude & Co Alpha-halomethyl amines
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
NZ194348A (en) * 1979-07-26 1982-09-14 Merrell Toraude & Co Fluorinated methyl-beta-alanine derivatives and pharmaceutical compositions
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
JP5902575B2 (en) * 2012-07-20 2016-04-13 国立大学法人お茶の水女子大学 Process for producing optically active fluorinated amine compound and optically active fluorinated amine compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines
GB1218135A (en) * 1967-07-28 1971-01-06 Abbott Lab Substituted phenethylamine derivatives

Also Published As

Publication number Publication date
IE47542B1 (en) 1984-04-18
JPS5416437A (en) 1979-02-07
DE2862407D1 (en) 1984-06-28
IE781077L (en) 1978-12-01
IT7849635A0 (en) 1978-05-31
EP0000034B1 (en) 1984-05-23
EP0000034A1 (en) 1978-12-20

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Legal Events

Date Code Title Description
ATS Application withdrawn