DK232387A - DIASTEREOISOMER TETRAHYDROPYRIDO (2,3-D) PYRIMIDINE DERIVATIVES - Google Patents

DIASTEREOISOMER TETRAHYDROPYRIDO (2,3-D) PYRIMIDINE DERIVATIVES

Info

Publication number: DK232387A
Authority: DK; Denmark
Prior art keywords: tetrahydropyrido; diastereoisomer; pyrimidine derivatives; pyrimidine; derivatives
Prior art date: 1986-06-06

Application number

DK232387A

Other languages

Danish (da)

Other versions

DK232387D0 (en

DK170023B1 (en

Inventor

Edward C Taylor

George Peter Beardsley

Chuan Shih

Stephen R Fletcher

Original Assignee

Univ Princeton

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-06-06

Filing date

1987-05-06

Publication date

1987-12-07

1987-05-06 Application filed by Univ Princeton filed Critical Univ Princeton

1987-05-06 Publication of DK232387D0 publication Critical patent/DK232387D0/en

1987-12-07 Publication of DK232387A publication Critical patent/DK232387A/en

1995-05-01 Application granted granted Critical

1995-05-01 Publication of DK170023B1 publication Critical patent/DK170023B1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK232387A 1986-06-06 1987-05-06 Diastereoisomeric tetrahydropyrido [2,3-d] pyrimidine derivatives and method for separating these diastereoisomeric compounds DK170023B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US87153986A	1986-06-06	1986-06-06
US87153986		1986-06-06

Publications (3)

Publication Number	Publication Date
DK232387D0 DK232387D0 (en)	1987-05-06
DK232387A true DK232387A (en)	1987-12-07
DK170023B1 DK170023B1 (en)	1995-05-01

Family

ID=25357673

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK232387A DK170023B1 (en)	1986-06-06	1987-05-06	Diastereoisomeric tetrahydropyrido [2,3-d] pyrimidine derivatives and method for separating these diastereoisomeric compounds

Country Status (15)

Country	Link
EP (1)	EP0248573A3 (en)
JP (1)	JPH07116190B2 (en)
KR (1)	KR950004894B1 (en)
CN (1)	CN1019391B (en)
AU (1)	AU592182B2 (en)
CA (1)	CA1301155C (en)
DK (1)	DK170023B1 (en)
EG (1)	EG19551A (en)
ES (1)	ES2003828A6 (en)
GR (1)	GR870783B (en)
NZ (1)	NZ219971A (en)
PH (1)	PH25509A (en)
PT (1)	PT84990B (en)
SU (1)	SU1627087A3 (en)
ZA (1)	ZA873083B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE60038B1 (en) *	1986-06-30	1994-05-18	Univ Princeton	4(3H)-oxo-5, 6, 7, 8-tetrahydropyrido-[2, 3-d]pyrimidine derivatives
GB8625019D0 (en) *	1986-10-18	1986-11-19	Wellcome Found	Compounds
US4895946A (en) *	1987-10-26	1990-01-23	The Trustees Of Princeton University	Process for the preparation of fused pyridine compounds
US4889859A (en) *	1988-02-05	1989-12-26	The Trustees Of Princeton University	Pyrido[2,3-d]pyrimidine derivatives
JP2830008B2 (en) *	1988-04-01	1998-12-02	武田薬品工業株式会社	Condensed pyrimidine derivative
US5223620A (en) *	1988-04-01	1993-06-29	Takeda Chemical Industries, Ltd.	Pyrido[2,3-d]pyrimidine compounds useful as intermediates
DK172753B1 (en) *	1988-05-25	1999-06-28	Lilly Co Eli	N- (5,6,7,8-tetrahydropyrido [2,3-d] pyrimidin-6-yl-alkanoyl) -glutamic acid derivatives, their use, pharmaceutical preparations
US5008391A (en) *	1989-07-07	1991-04-16	Eli Lilly And Company	Enantioselective synthesis of antifolates
US5066828A (en) *	1990-04-12	1991-11-19	Merrell Dow Pharmaceuticals Inc.	Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
IL137685A0 (en) *	1998-02-11	2001-10-31	Lilly Co Eli	Processes and intermediates useful to make antifolates
CN110749692B (en) *	2019-10-15	2022-03-18	扬子江药业集团有限公司	Separation and detection method of L-glutamic acid diethyl ester hydrochloride and optical isomer thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA861235B (en) *	1985-03-08	1986-10-29	Univ Princeton	Pyrido(2,3-d)pyrimidine derivatives

1987
- 1987-04-14 NZ NZ219971A patent/NZ219971A/en unknown
- 1987-04-29 ZA ZA873083A patent/ZA873083B/en unknown
- 1987-05-04 EG EG26087A patent/EG19551A/en active
- 1987-05-06 DK DK232387A patent/DK170023B1/en not_active IP Right Cessation
- 1987-05-07 JP JP62109938A patent/JPH07116190B2/en not_active Expired - Fee Related
- 1987-05-12 AU AU72731/87A patent/AU592182B2/en not_active Ceased
- 1987-05-19 GR GR870783A patent/GR870783B/en unknown
- 1987-05-22 EP EP87304580A patent/EP0248573A3/en not_active Withdrawn
- 1987-05-25 CA CA000537814A patent/CA1301155C/en not_active Expired - Lifetime
- 1987-06-02 PT PT84990A patent/PT84990B/en not_active IP Right Cessation
- 1987-06-04 PH PH35342A patent/PH25509A/en unknown
- 1987-06-05 ES ES8701666A patent/ES2003828A6/en not_active Expired
- 1987-06-05 SU SU874202677A patent/SU1627087A3/en active
- 1987-06-05 KR KR1019870005798A patent/KR950004894B1/en not_active IP Right Cessation
- 1987-06-06 CN CN87104103A patent/CN1019391B/en not_active Expired

Also Published As

Publication number	Publication date
CN1019391B (en)	1992-12-09
EP0248573A2 (en)	1987-12-09
AU592182B2 (en)	1990-01-04
JPS6339878A (en)	1988-02-20
GR870783B (en)	1987-09-25
KR880000431A (en)	1988-03-25
DK232387D0 (en)	1987-05-06
EP0248573A3 (en)	1989-06-14
CA1301155C (en)	1992-05-19
PT84990B (en)	1990-03-08
EG19551A (en)	1996-02-29
JPH07116190B2 (en)	1995-12-13
NZ219971A (en)	1989-08-29
PT84990A (en)	1987-07-01
DK170023B1 (en)	1995-05-01
AU7273187A (en)	1987-12-10
SU1627087A3 (en)	1991-02-07
ES2003828A6 (en)	1988-11-16
PH25509A (en)	1991-07-24
KR950004894B1 (en)	1995-05-15
ZA873083B (en)	1987-10-26
CN87104103A (en)	1987-12-30

Publication	Publication Date	Title
DK0447891T3 (en)	1994-05-30	Thieno (2,3-d) pyrimidine derivatives
DK0432677T3 (en)	1996-04-09	N- (pyrrolo (2,3-d) pyrimidine-3-ylacyl-glutamic acid derivatives
DE3788385D1 (en)	1994-01-20	Pyrimidine derivatives.
DK495287D0 (en)	1987-09-21	2-OR 3-ARYL-SUBSTITUTED IMIDAZO (1,2-A) PYRIDIA DOWN
DE3888897D1 (en)	1994-05-11	Imidazo [1,2-b] pyridazine derivatives.
DK0384522T3 (en)	1993-04-19	Antiviral tetrahydroimidazo (1,4) benzodiazepine-2-thiones
DE3675846D1 (en)	1991-01-10	GUANINE DERIVATIVES.
FI871123A (en)	1987-09-15	PYRAZOLO / 3,4-D / PYRIMIDINDERIVAT, DERAS FRAMSTAELLNING OCH ANVAENDNING.
DK232387A (en)	1987-12-07	DIASTEREOISOMER TETRAHYDROPYRIDO (2,3-D) PYRIMIDINE DERIVATIVES
DE3779358D1 (en)	1992-07-02	PYRIDO (2,3-B) INDOLE.
DK307387A (en)	1987-12-31	4 (3H) -oxo-5,6,7,8-tetrahydro-pyrido (2,3-d) pyrimidine derivatives
NO895217L (en)	1990-07-09	SUBSTITUTED PYRIDO (2,3-D) PYRIMIDINES.
DK382788D0 (en)	1988-07-08	4-AMINO-SUBSTITUTED 1,2-DIHYDROXY-NAPHTHALENE DERIVATIVES
DE3682244D1 (en)	1991-12-05	SUBSTITUTED DIHYDROIMIDAZO (1,2-A) CHINOXALINE DERIVATIVES.
DE3276808D1 (en)	1987-08-27	PYRIDO (2,3-D) PYRIMIDINES
PH22448A (en)	1988-09-12	Substituted carboxy-thiazolo/3,2-a/pyrimidine derivatives
DK0417840T3 (en)	1995-02-13	Antiviral tetrahydroimidazo (1,4) benzodiazepines
NZ226123A (en)	1990-03-27	2-amino-pyrido(2,3-d)pyrimidine derivatives
ATE63120T1 (en)	1991-05-15	4(3H)-OXO-5,6,7,8-TETRAHYDROPYRIDO(2,3D>PYRIMIDINE DERIVATIVES.
IL82249A0 (en)	1987-10-30	Diastereoisomeric tetrahydropyrido(2,3-d)pyrimidine derivatives
IE852585L (en)	1986-04-19	PYRIDO (2,3-d) PYRIMIDINES
IE852586L (en)	1986-04-19	PYRIDO (2,3-d) PYRIMIDINES
FI931574A (en)	1993-04-07	4-SUBSTITUERADE PYRAZOLO / 3,4-D / PYRIMIDINDERIVAT
IT8620712A0 (en)	1986-06-06	PROCEDURE FOR THE PREPARATION OF -9-(2-BENZOYLOXY-ETHOXY-METHYL)GUANINE.
ATE58736T1 (en)	1990-12-15	GUANINE DERIVATIVES.

Legal Events

Date	Code	Title	Description
1995-05-01	B1	Patent granted (law 1993)
2006-02-27	PBP	Patent lapsed	Country of ref document: DK