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DK234780A - 6beta,7beta,15,16-dimethylen-1,4-androstadien-3-oner fremgangsmaade til fremstilling heraf og anvendelsen heraf som laegemiddel - Google Patents

6beta,7beta,15,16-dimethylen-1,4-androstadien-3-oner fremgangsmaade til fremstilling heraf og anvendelsen heraf som laegemiddel

Info

Publication number
DK234780A
DK234780A DK234780A DK234780A DK234780A DK 234780 A DK234780 A DK 234780A DK 234780 A DK234780 A DK 234780A DK 234780 A DK234780 A DK 234780A DK 234780 A DK234780 A DK 234780A
Authority
DK
Denmark
Prior art keywords
androstadien
6beta
7beta
oner
dimethylene
Prior art date
Application number
DK234780A
Other languages
English (en)
Other versions
DK145140C (da
DK145140B (da
Inventor
R Wiechert
D Bittler
U Kerb
K Prezewowsky
J Casals-Stenzel
W Losert
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK234780A publication Critical patent/DK234780A/da
Publication of DK145140B publication Critical patent/DK145140B/da
Application granted granted Critical
Publication of DK145140C publication Critical patent/DK145140C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • C07J53/008—3 membered carbocyclic rings in position 15/16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Control Of High-Frequency Heating Circuits (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK234780A 1979-05-31 1980-05-30 Analogifremgangsmaade til fremstilling af 6beta,7beta,15,16-dimethylen-1,4-androstadien-3-oner DK145140C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19792922500 DE2922500A1 (de) 1979-05-31 1979-05-31 6 beta .7 beta
DE2922500 1979-05-31

Publications (3)

Publication Number Publication Date
DK234780A true DK234780A (da) 1980-12-01
DK145140B DK145140B (da) 1982-09-13
DK145140C DK145140C (da) 1983-02-21

Family

ID=6072347

Family Applications (1)

Application Number Title Priority Date Filing Date
DK234780A DK145140C (da) 1979-05-31 1980-05-30 Analogifremgangsmaade til fremstilling af 6beta,7beta,15,16-dimethylen-1,4-androstadien-3-oner

Country Status (16)

Country Link
US (1) US4291029A (da)
EP (1) EP0019690B1 (da)
JP (1) JPS55162799A (da)
AT (1) ATE880T1 (da)
AU (1) AU531057B2 (da)
CA (1) CA1134814A (da)
CS (1) CS214712B2 (da)
DD (1) DD151172A5 (da)
DE (2) DE2922500A1 (da)
DK (1) DK145140C (da)
ES (1) ES8101082A1 (da)
HU (2) HU181714B (da)
IE (1) IE49899B1 (da)
IL (1) IL60185A (da)
SU (1) SU873890A3 (da)
YU (1) YU41926B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3111951A1 (de) * 1981-03-23 1982-09-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen 7(alpha)-alkoxycarbonyl-15ss-methylen-4-androstene, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3213962A1 (de) * 1982-04-13 1983-10-13 Schering AG, 1000 Berlin und 4709 Bergkamen 1(alpha).2(alpha);6(beta).7(beta).15(beta).16(beta)-trimethylen-3-oxo-17(alpha)-pregn-4-en-21.17-carbolacton, dessen herstellung und verwendung als arzneimittel
DE3222265A1 (de) * 1982-06-09 1983-12-15 Schering AG, 1000 Berlin und 4709 Bergkamen 6ss.7ss-methylen-17(alpha)-pregn-4-en-21.17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE3227598A1 (de) * 1982-07-22 1984-01-26 Schering AG, 1000 Berlin und 4709 Bergkamen 7(alpha)-acylthio-15.16-methylen-3-oxo-17(alpha)-pregna-1.4-dien-21,17-carbolactone, verfahren zu ihrer herstellung und verwendung als arzneimittel
JPS5921698A (ja) * 1982-07-22 1984-02-03 シエ−リング・アクチエンゲゼルシヤフト １７α−プレグネ−４−エン−３−オキソ−２１−カルボン酸エステル、その製法およびこれを含有する抗アンドロゲン作用を有する医薬
DE3240510A1 (de) * 1982-10-29 1984-05-03 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 7(alpha)-acylthio-1(alpha),2(alpha)-methylen-3-oxo-17(alpha)-pregn-4-en-21,17-carbolactone, deren herstellung und diese enthaltende arzneimittel
FI77669C (fi) * 1983-04-13 1989-04-10 Ciba Geigy Ag 20-spiroxaner och analoger, som innehaoller en oeppen ring e, foerfarande foer deras framstaellning samt dessa innehaollande farmaceutiska preparat.
DE3326013A1 (de) * 1983-07-15 1985-01-24 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-methylen-17(alpha)-pregna-4,6-dien-21-carbonsaeuresalze, diese enthaltende pharmazeutische praeparate sowie verfahren zu deren herstellung
EP0134529B1 (de) * 1983-08-17 1990-03-21 Schering Aktiengesellschaft 7-alpha-Substituierte 3-Oxo-17alpha-pregn-4-en-21.17-carbolactone, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE3410880A1 (de) * 1984-03-21 1985-10-03 Schering AG, Berlin und Bergkamen, 1000 Berlin 17-substituierte estradiene und estratriene
FR2697328A1 (fr) * 1992-10-23 1994-04-29 Giat Ind Sa Munition fumigène.
US6787531B1 (en) * 1999-08-31 2004-09-07 Schering Ag Pharmaceutical composition for use as a contraceptive
US20020132801A1 (en) * 2001-01-11 2002-09-19 Schering Aktiengesellschaft Drospirenone for hormone replacement therapy
DE102007027637A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027635A1 (de) 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-19-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007027636A1 (de) * 2007-06-12 2008-12-18 Bayer Schering Pharma Aktiengesellschaft 17ß-Cyano-18a-homo-19-nor-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063498A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15,16-Methylen-steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063500A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-(1'-Propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063501A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15, 16-Methylen-17-hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063496A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 15,16-Methylen-17-(1'-propenyl)-17-3'-oxidoestra-4-en-3-on-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063495A1 (de) 2007-12-29 2009-09-17 Bayer Schering Pharma Aktiengesellschaft 19-Nor-Steroidderivate mit einer 15α,16α-Methylengruppe und einem gesättigten 17,17-Spirolactonring, deren Verwendung sowie diese Derivate enthaltende Arzneimittel
DE102007063503A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-19-nor-21-carbonsäure-Steroid y-Lacton-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102007063499A1 (de) 2007-12-29 2009-07-02 Bayer Schering Pharma Aktiengesellschaft Steroid-17,17-Lactol-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel
DE102008026793A1 (de) 2008-06-02 2009-12-03 Bayer Schering Pharma Aktiengesellschaft C-Ring-substituierte Pregn-4-en-21,17-carbolactone, sowie diese enthaltende pharmazeutische Präparate
MX2014005367A (es) 2011-11-04 2014-07-09 Bayer Pharma AG 18-metil-6,7-metilen-3-oxo-17-pregn-4-en-21,17b-carbolactona, preparados farmaceuticos que contienen los compuestos mencionados y su uso en la terapia de la endometriosis.
WO2016063269A1 (en) 2014-10-20 2016-04-28 Prendergast Patrick T Use of antagonists to the nuclear steroid receptor alone or in combination as direct antiviral agents to inhibit alphavirus, togaviridae, arenaviridae, filoviridae, bunyaviridae, flaviviridae and rhabdoviridae

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3254074A (en) * 1962-04-25 1966-05-31 Merck & Co Inc Spiroxenones
DE2264189C3 (de) * 1972-12-29 1979-05-31 Merck & Co., Inc., Rahway, N.J. (V.St.A.) 3'-(3-Oxo-17beta-hydroxy-6,7-methylen-androst-4en-bzw.-l,4-dien-17 a-yl) -propionsäureverbindungen, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Mittel
DE2652761C2 (de) * 1976-11-16 1985-11-21 Schering AG, 1000 Berlin und 4709 Bergkamen 15,16-Methylen-Spirolactone, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
ES469510A1 (es) * 1977-05-16 1978-12-01 Schering Ag Procedimiento para la preparacion de 17beta hidroxi-4-an- drosten-3-onas.

Also Published As

Publication number Publication date
IE801127L (en) 1980-11-30
AU531057B2 (en) 1983-08-11
DK145140C (da) 1983-02-21
ATE880T1 (de) 1982-05-15
YU132980A (en) 1983-02-28
JPS55162799A (en) 1980-12-18
CA1134814A (en) 1982-11-02
AU5874580A (en) 1980-12-04
DK145140B (da) 1982-09-13
CS214712B2 (en) 1982-05-28
HU187419B (en) 1986-01-28
DE2922500A1 (de) 1980-12-04
JPH0214360B2 (da) 1990-04-06
EP0019690A1 (de) 1980-12-10
US4291029A (en) 1981-09-22
IE49899B1 (en) 1986-01-08
EP0019690B1 (de) 1982-04-21
ES491916A0 (es) 1980-12-16
DD151172A5 (de) 1981-10-08
IL60185A (en) 1983-06-15
DE3060297D1 (en) 1982-06-03
YU41926B (en) 1988-02-29
SU873890A3 (ru) 1981-10-15
HU181714B (en) 1983-11-28
ES8101082A1 (es) 1980-12-16
IL60185A0 (en) 1980-07-31

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