DK2260873T3 - Pcylering af proteiner - Google Patents
Pcylering af proteinerInfo
- Publication number
- DK2260873T3 DK2260873T3 DK09162203.5T DK09162203T DK2260873T3 DK 2260873 T3 DK2260873 T3 DK 2260873T3 DK 09162203 T DK09162203 T DK 09162203T DK 2260873 T3 DK2260873 T3 DK 2260873T3
- Authority
- DK
- Denmark
- Prior art keywords
- pcyling
- proteins
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/548—Phosphates or phosphonates, e.g. bone-seeking
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09162203.5A EP2260873B1 (en) | 2009-06-08 | 2009-06-08 | Pcylation of proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2260873T3 true DK2260873T3 (da) | 2019-09-16 |
Family
ID=41011846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK09162203.5T DK2260873T3 (da) | 2009-06-08 | 2009-06-08 | Pcylering af proteiner |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP2260873B1 (da) |
DK (1) | DK2260873T3 (da) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI1988910T1 (en) * | 2006-02-28 | 2018-02-28 | Kodiak Sciences Inc. | Polymeric conjugates containing acryloyloxyethylphosphorylcholine and their preparations |
US8765432B2 (en) | 2009-12-18 | 2014-07-01 | Oligasis, Llc | Targeted drug phosphorylcholine polymer conjugates |
ES2905690T3 (es) * | 2010-04-15 | 2022-04-11 | Kodiak Sciences Inc | Polímeros que contienen zwitteriones de alto peso molecular |
US10046021B2 (en) | 2013-02-05 | 2018-08-14 | Tpcera Ltd. | Phosphorylcholine conjugates and uses thereof |
US9987372B2 (en) | 2013-02-05 | 2018-06-05 | Tpcera Ltd. | Phosphorylcholine conjugates and uses thereof |
US10702608B2 (en) | 2013-09-08 | 2020-07-07 | Kodiak Sciences Inc. | Factor VIII zwitterionic polymer conjugates |
US9840553B2 (en) | 2014-06-28 | 2017-12-12 | Kodiak Sciences Inc. | Dual PDGF/VEGF antagonists |
JP2017534612A (ja) | 2014-10-14 | 2017-11-24 | ポリセリックス・リミテッド | Pegの部分を含めた脱離基を含む試薬を用いるペプチド又はタンパク質のコンジュゲーションのための方法 |
KR20210013299A (ko) | 2014-10-17 | 2021-02-03 | 코디악 사이언시스 인코포레이티드 | 부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트 |
US10722475B2 (en) * | 2014-11-26 | 2020-07-28 | The Regents Of The University Of California | Stealth nanocapsules for protein delivery |
KR20180104635A (ko) | 2015-12-30 | 2018-09-21 | 코디악 사이언시스 인코포레이티드 | 항체 및 이의 접합체 |
JP7038663B2 (ja) | 2016-04-14 | 2022-03-18 | ポリセリックス・リミテッド | 環中に少なくとも2個の(-ch2-ch2-0-)単位を含むリンカーを含むコンジュゲート及びコンジュゲート試薬 |
GB201608936D0 (en) | 2016-05-20 | 2016-07-06 | Polytherics Ltd | Novel conjugates and novel conjugating reagents |
AU2019227997A1 (en) | 2018-03-02 | 2020-09-24 | Kodiak Sciences Inc. | IL-6 antibodies and fusion constructs and conjugates thereof |
EP4041312A4 (en) | 2019-10-10 | 2023-12-20 | Kodiak Sciences Inc. | METHOD FOR TREATING AN EYE DISORDER |
US20240277853A1 (en) * | 2021-06-04 | 2024-08-22 | Tagcyx Biotechnologies Inc. | Medium-molecular-weight compound conjugate for improving pharmacokinetic profile of medium-molecular-weight compound and method of producing the same |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
US6071980A (en) | 1997-08-27 | 2000-06-06 | E. I. Du Pont De Nemours And Company | Atom transfer radical polymerization |
AUPP337298A0 (en) | 1998-05-07 | 1998-05-28 | University Of Melbourne, The | Process for microgel preparation |
ATE279447T1 (de) | 1998-09-29 | 2004-10-15 | Ciba Sc Holding Ag | Verfahren zur herstellung von polymeren enthaltend endständige n-0 gruppen |
EP1325046B1 (en) | 2000-10-06 | 2007-06-27 | Biocompatibles UK Limited | Zwitterionic polymers |
WO2003062290A1 (en) | 2002-01-16 | 2003-07-31 | Biocompatibles Uk Limited | Polymer conjugates |
ATE486613T1 (de) | 2002-03-07 | 2010-11-15 | Biocompatibles Uk Ltd | Mit nucleinsäure complexierte block-copolymere |
GB0301014D0 (en) | 2003-01-16 | 2003-02-19 | Biocompatibles Ltd | Conjugation reactions |
SI1988910T1 (en) * | 2006-02-28 | 2018-02-28 | Kodiak Sciences Inc. | Polymeric conjugates containing acryloyloxyethylphosphorylcholine and their preparations |
US8575397B2 (en) | 2007-02-14 | 2013-11-05 | Biocompatibles Uk Limited | Derivatisation of biological molecules |
-
2009
- 2009-06-08 EP EP09162203.5A patent/EP2260873B1/en active Active
- 2009-06-08 DK DK09162203.5T patent/DK2260873T3/da active
Also Published As
Publication number | Publication date |
---|---|
EP2260873A1 (en) | 2010-12-15 |
EP2260873B1 (en) | 2019-07-24 |
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