DK21585A - Substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-oner, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne - Google Patents

Substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-oner, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne Download PDF

Info

Publication number: DK21585A
Authority: DK; Denmark
Prior art keywords: compounds; dibenz; azepin; dihydro; substituted
Prior art date: 1984-01-21

Application number

DK21585A

Other languages

English (en)

Other versions

DK159441B (da

DK159441C (da

DK21585D0 (da

Inventor

Wolfgang Eberlein

Guenter Trummlitz

Wolfhard Engel

Guenther Schmidt

Rudolf Hammer

Antonio Giachetti

Original Assignee

Thomae Gmbh Dr K

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-01-21

Filing date

1985-01-17

Publication date

1985-07-22

1985-01-17 Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K

1985-01-17 Publication of DK21585D0 publication Critical patent/DK21585D0/da

1985-07-22 Publication of DK21585A publication Critical patent/DK21585A/da

1990-10-15 Publication of DK159441B publication Critical patent/DK159441B/da

1991-03-18 Application granted granted Critical

1991-03-18 Publication of DK159441C publication Critical patent/DK159441C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/20—Dibenz [b, e] azepines; Hydrogenated dibenz [b, e] azepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Hydrogenated Pyridines (AREA)

DK021585A 1984-01-21 1985-01-17 11-substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-on-derivater, laegemidler indeholdende disse forbindelser og analogifremgangsmaade til forbindelsernes fremstilling DK159441C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3402060		1984-01-21
DE19843402060 DE3402060A1 (de)	1984-01-21	1984-01-21	Substituierte 5,11-dihydro-6h-dibenz(b,e)azepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (4)

Publication Number	Publication Date
DK21585D0 DK21585D0 (da)	1985-01-17
DK21585A true DK21585A (da)	1985-07-22
DK159441B DK159441B (da)	1990-10-15
DK159441C DK159441C (da)	1991-03-18

Family

ID=6225562

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK021585A DK159441C (da)	1984-01-21	1985-01-17	11-substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-on-derivater, laegemidler indeholdende disse forbindelser og analogifremgangsmaade til forbindelsernes fremstilling

Country Status (24)

Country	Link
US (1)	US4567178A (da)
EP (1)	EP0149840B1 (da)
JP (1)	JPH0662575B2 (da)
KR (1)	KR910006986B1 (da)
AT (1)	ATE42553T1 (da)
AU (1)	AU570761B2 (da)
CA (1)	CA1241651A (da)
CS (1)	CS247094B2 (da)
DD (1)	DD235259A5 (da)
DE (2)	DE3402060A1 (da)
DK (1)	DK159441C (da)
ES (2)	ES8601908A1 (da)
FI (1)	FI79534C (da)
GR (1)	GR850131B (da)
HU (1)	HU193250B (da)
IE (1)	IE57754B1 (da)
IL (1)	IL74101A (da)
NO (1)	NO161619C (da)
NZ (1)	NZ210875A (da)
PH (1)	PH23209A (da)
PL (2)	PL142866B1 (da)
PT (1)	PT79837B (da)
SU (1)	SU1308196A3 (da)
ZA (1)	ZA85414B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3531682A1 (de) *	1985-09-05	1987-03-12	Thomae Gmbh Dr K	(+)-6-chlor-5,10-dihydro-5-((1-methyl-4- piperidinyl)acetyl)-11h-dibenzo(b,e)(1,4) diazepin-11-on, seine isolierung und verwendung als arzneimittel
IT8819192A0 (it) *	1988-01-25	1988-01-25	Angeli Inst Spa	Amminochetoni di dibenzo e piridobenzo azepinoni sostituiti e composizioni farmaceutiche.
US5256699A (en) *	1988-10-18	1993-10-26	Ciba-Geify Corporation	Dispersible tablet formulation of diclofenac acid free base
DE3838912A1 (de) *	1988-11-17	1990-05-23	Thomae Gmbh Dr K	Mittel zur behandlung von akuten und chronischen obstruktiven atemwegserkrankungen
US6613905B1 (en)	1998-01-21	2003-09-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
AU2335699A (en) *	1998-01-21	1999-08-09	Kyowa Hakko Kogyo Co. Ltd.	Chemokine receptor antagonists and methods of use therefor
AU2331999A (en)	1998-01-21	1999-08-09	Kyowa Hakko Kogyo Co. Ltd.	Chemokine receptor antagonists and methods of use therefor
US6509346B2 (en)	1998-01-21	2003-01-21	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
NZ505329A (en) *	1998-06-08	2003-05-30	Theravance Inc	Two heteroaryl or aryl containing compounds covalently attached via a linker useful as muscarinic receptor antagonists
US7271176B2 (en) *	1998-09-04	2007-09-18	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use thereof
US6693202B1 (en)	1999-02-16	2004-02-17	Theravance, Inc.	Muscarinic receptor antagonists
UA73543C2 (uk)	1999-12-07	2005-08-15	Тераванс, Інк.	Похідні сечовини, фармацевтична композиція та застосування похідного при приготуванні лікарського засобу для лікування захворювання, яке опосередковується мускариновим рецептором
JP2003516390A (ja)	1999-12-07	2003-05-13	セラヴァンスインコーポレーテッド	ムスカリンレセプターアンタゴニスト活性を有するカルバメート誘導体
US7541365B2 (en)	2001-11-21	2009-06-02	Millennium Pharmaceuticals, Inc.	Chemokine receptor antagonists and methods of use therefor
TWI291467B (en) *	2002-11-13	2007-12-21	Millennium Pharm Inc	CCR1 antagonists and methods of use therefor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1795176C3 (de) *	1968-08-20	1974-10-24	Dr. Karl Thomae Gmbh, 7950 Biberach	hT-substituierte 5-Aminoacetyl-5,10-dihydro-l lH-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11one und Verfahren zu ihrer Herstellung
CH624682A5 (da) *	1976-11-10	1981-08-14	Sandoz Ag
DE2918832A1 (de) *	1979-05-10	1980-11-20	Basf Ag	5,6-dihydro-11-alkylen-morphantridin- 6-one
DE3204157A1 (de) *	1982-02-06	1983-08-11	Dr. Karl Thomae Gmbh, 7950 Biberach	Substituierte dibenzodiazepinone, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

1984
- 1984-01-21 DE DE19843402060 patent/DE3402060A1/de not_active Withdrawn
- 1984-12-22 EP EP84116184A patent/EP0149840B1/de not_active Expired
- 1984-12-22 AT AT84116184T patent/ATE42553T1/de not_active IP Right Cessation
- 1984-12-22 DE DE8484116184T patent/DE3477927D1/de not_active Expired
1985
- 1985-01-02 PH PH31747A patent/PH23209A/en unknown
- 1985-01-07 US US06/689,325 patent/US4567178A/en not_active Expired - Fee Related
- 1985-01-08 PL PL1985255144A patent/PL142866B1/pl unknown
- 1985-01-09 SU SU853834159A patent/SU1308196A3/ru active
- 1985-01-17 DK DK021585A patent/DK159441C/da not_active IP Right Cessation
- 1985-01-17 GR GR850131A patent/GR850131B/el unknown
- 1985-01-17 DD DD85272625A patent/DD235259A5/de unknown
- 1985-01-18 AU AU37792/85A patent/AU570761B2/en not_active Ceased
- 1985-01-18 IE IE117/85A patent/IE57754B1/en not_active IP Right Cessation
- 1985-01-18 JP JP60007333A patent/JPH0662575B2/ja not_active Expired - Lifetime
- 1985-01-18 FI FI850228A patent/FI79534C/fi not_active IP Right Cessation
- 1985-01-18 IL IL74101A patent/IL74101A/xx not_active IP Right Cessation
- 1985-01-18 PT PT79837A patent/PT79837B/pt not_active IP Right Cessation
- 1985-01-18 NO NO850216A patent/NO161619C/no unknown
- 1985-01-18 ES ES539668A patent/ES8601908A1/es not_active Expired
- 1985-01-18 ZA ZA85414A patent/ZA85414B/xx unknown
- 1985-01-18 CA CA000472168A patent/CA1241651A/en not_active Expired
- 1985-01-18 CS CS85374A patent/CS247094B2/cs unknown
- 1985-01-18 NZ NZ210875A patent/NZ210875A/en unknown
- 1985-01-18 PL PL1985251603A patent/PL142903B1/pl unknown
- 1985-01-19 KR KR1019850000318A patent/KR910006986B1/ko not_active IP Right Cessation
- 1985-01-21 HU HU85240A patent/HU193250B/hu not_active IP Right Cessation
- 1985-07-10 ES ES545025A patent/ES8604524A1/es not_active Expired

Also Published As

Publication number	Publication date
PL255144A1 (en)	1986-08-12
PL251603A1 (en)	1985-12-17
DK159441B (da)	1990-10-15
IE850117L (en)	1985-07-21
IE57754B1 (en)	1993-03-24
ES545025A0 (es)	1986-02-01
DE3477927D1 (en)	1989-06-01
ATE42553T1 (de)	1989-05-15
NO161619B (no)	1989-05-29
FI850228A0 (fi)	1985-01-18
IL74101A0 (en)	1985-04-30
JPH0662575B2 (ja)	1994-08-17
JPS60161970A (ja)	1985-08-23
PT79837A (en)	1985-02-01
HUT37141A (en)	1985-11-28
PL142866B1 (en)	1987-12-31
KR910006986B1 (ko)	1991-09-14
AU3779285A (en)	1985-08-01
DK159441C (da)	1991-03-18
IL74101A (en)	1988-09-30
EP0149840A1 (de)	1985-07-31
FI850228L (fi)	1985-07-22
PL142903B1 (en)	1987-12-31
ES539668A0 (es)	1985-11-16
DK21585D0 (da)	1985-01-17
CA1241651A (en)	1988-09-06
DD235259A5 (de)	1986-04-30
ES8604524A1 (es)	1986-02-01
NO850216L (no)	1985-07-22
PT79837B (en)	1986-12-18
NO161619C (no)	1989-09-06
SU1308196A3 (ru)	1987-04-30
AU570761B2 (en)	1988-03-24
DE3402060A1 (de)	1985-08-01
US4567178A (en)	1986-01-28
KR850005414A (ko)	1985-08-26
NZ210875A (en)	1987-07-31
FI79534B (fi)	1989-09-29
HU193250B (en)	1987-08-28
CS247094B2 (en)	1986-11-13
GR850131B (da)	1985-05-17
FI79534C (fi)	1990-01-10
PH23209A (en)	1989-06-06
ZA85414B (en)	1986-09-24
ES8601908A1 (es)	1985-11-16
EP0149840B1 (de)	1989-04-26

Publication	Publication Date	Title
DK21585A (da)	1985-07-22	Substituerede 5,11-dihydro-6h-dibenz(b,e)azepin-6-oner, fremgangsmaade til deres fremstilling og laegemidler indeholdende forbindelserne
ES2093099T3 (es)	1996-12-16	Preparacion de piperidinas sustituidas.
ATE51617T1 (de)	1990-04-15	Verfahren zur herstellung von 4-phenyl-pyrrolderivaten.
ATE48835T1 (de)	1990-01-15	Chinolylglycinamidderivate, verfahren zu ihrer herstellung und therapeutische verwendung als psychotrope.
DK282285A (da)	1985-12-23	Hidtil ukendte 8-alkylthio-2-piperazino-pyrimido(5,4-d)pyrimidiner,deres fremstilling og laegemidler indeholdende disse forbindelser
ATE61573T1 (de)	1991-03-15	Neue kristalline salze von aryloxypropanolaminen, verfahren zu ihrer herstellung und ihre verwendung.
PT80791A (fr)	1985-08-01	Procede de preparation de nouvelles phenyl-naphtiridines utiles notamment comme medicaments anti-ulceres
NO871575L (no)	1987-10-16	Fremgangsmaate for fremstilling av 1,5-benztiazepin-derivater.
ES2064533T3 (es)	1995-02-01	Acido(1,2,3,4-tetrahidro-9-acridinimino)-ciclohexanocarboxilico y compuestos relacionados, un procedimiento para su preparacion y su uso como medicamentos.
DE3850196D1 (de)	1994-07-21	Modifizierte Splenopentine, Verfahren zu ihrer Herstellung und ihre Verwendung.
MX9206997A (es)	1993-06-01	Procedimiento para la preparacion de derivados de trifluorobenceno.
DE59007185D1 (de)	1994-10-27	Substituierte 1.2.3.4-Oxatriazolium-5-olate, Verfahren zu ihrer Herstellung und ihre Verwendung.
ATE60599T1 (de)	1991-02-15	Chinolin-8-carbonsaeureazolide, ein verfahren zu ihrer herstellung und ihre verwendung als herbizide.
ATE90677T1 (de)	1993-07-15	Substituierte 3-aminosydnonimine, verfahren zu ihrer herstellung und ihre verwendung.
ATE73455T1 (de)	1992-03-15	4,4-dimethyltetrahydropyr-2-on-derivate, verfahren zu ihrer herstellung und ihre verwendung zur synthese von pyretrinverbindungen.
PT89356A (pt)	1989-12-29	Processo para a preparacao de derivados da 2-amino-tetra-hidro-isoquinolina e de composicoes farmaceuticas contendo os mesmos

Legal Events

Date	Code	Title	Description
1996-09-16	PBP	Patent lapsed