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DK2016080T3 - Dihydropyrazolopyrimidinon-derivater - Google Patents

Dihydropyrazolopyrimidinon-derivater

Info

Publication number
DK2016080T3
DK2016080T3 DK07742843.1T DK07742843T DK2016080T3 DK 2016080 T3 DK2016080 T3 DK 2016080T3 DK 07742843 T DK07742843 T DK 07742843T DK 2016080 T3 DK2016080 T3 DK 2016080T3
Authority
DK
Denmark
Prior art keywords
dihydropyrazolopyrimidinon
derivatives
dihydropyrazolopyrimidinon derivatives
Prior art date
Application number
DK07742843.1T
Other languages
English (en)
Inventor
Toshihiro Sakamoto
Satoshi Sunami
Fuyuki Yamamoto
Kenji Niiyama
Makoto Bamba
Keiji Takahashi
Hidetomo Furuyama
Takeshi Sagara
Sachie Otsuki
Toshihide Nishibata
Takashi Yoshizumi
Hiroshi Hirai
Original Assignee
Banyu Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38655640&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2016080(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Banyu Pharma Co Ltd filed Critical Banyu Pharma Co Ltd
Application granted granted Critical
Publication of DK2016080T3 publication Critical patent/DK2016080T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK07742843.1T 2006-04-27 2007-04-25 Dihydropyrazolopyrimidinon-derivater DK2016080T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006124208 2006-04-27
PCT/JP2007/059408 WO2007126122A1 (en) 2006-04-27 2007-04-25 Dihydropyrazolopyrimidinone derivatives

Publications (1)

Publication Number Publication Date
DK2016080T3 true DK2016080T3 (da) 2010-11-22

Family

ID=38655640

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07742851.4T DK2017278T3 (da) 2006-04-27 2007-04-25 Dihydropyrazolopyrimidinonderivat
DK07742843.1T DK2016080T3 (da) 2006-04-27 2007-04-25 Dihydropyrazolopyrimidinon-derivater

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK07742851.4T DK2017278T3 (da) 2006-04-27 2007-04-25 Dihydropyrazolopyrimidinonderivat

Country Status (39)

Country Link
US (4) US7935708B2 (da)
EP (2) EP2016080B1 (da)
JP (2) JP4513919B2 (da)
KR (1) KR101409161B1 (da)
CN (1) CN101432284B (da)
AR (1) AR060635A1 (da)
AT (1) ATE475662T1 (da)
AU (1) AU2007244185B2 (da)
BR (1) BRPI0710081A2 (da)
CA (1) CA2650119C (da)
CR (1) CR10359A (da)
CY (2) CY1111069T1 (da)
DE (1) DE602007008085D1 (da)
DK (2) DK2017278T3 (da)
DO (1) DOP2007000084A (da)
EC (1) ECSP088812A (da)
ES (2) ES2609087T3 (da)
GT (1) GT200800211A (da)
HK (1) HK1132498A1 (da)
HN (1) HN2008001532A (da)
HR (2) HRP20100563T1 (da)
HU (1) HUE032987T2 (da)
IL (1) IL194367A (da)
LT (1) LT2017278T (da)
MA (1) MA30428B1 (da)
MX (1) MX2008013063A (da)
MY (1) MY145408A (da)
NO (1) NO341617B1 (da)
NZ (1) NZ571196A (da)
PE (1) PE20080695A1 (da)
PL (2) PL2017278T3 (da)
PT (2) PT2017278T (da)
RU (1) RU2437885C2 (da)
SI (2) SI2016080T1 (da)
SV (1) SV2009003060A (da)
TW (1) TWI409262B (da)
UA (1) UA96152C2 (da)
WO (2) WO2007126128A1 (da)
ZA (1) ZA200807748B (da)

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CN115197221B (zh) * 2021-04-02 2024-05-24 轩竹(北京)医药科技有限公司 二氢吡唑并嘧啶酮类大环衍生物及其用途
AU2022265718A1 (en) 2021-04-29 2023-11-02 Novartis Ag Deubiquitinase-targeting chimeras and related methods
CN117222648A (zh) 2021-04-30 2023-12-12 微境生物医药科技(上海)有限公司 作为Wee-1抑制剂的稠环化合物及其制备方法和用途
JP2024520969A (ja) 2021-05-28 2024-05-28 江蘇天士力帝益薬業有限公司 Ｗｅｅ１阻害剤とその用途
WO2023041066A1 (zh) * 2021-09-18 2023-03-23 优领医药科技(香港)有限公司 含嘧啶并二氢吡唑啉酮类衍生物、其药学上可接受的盐及其制备方法和应用
CN113735863A (zh) * 2021-09-29 2021-12-03 武汉九州钰民医药科技有限公司 Wee1抑制剂adavosertib的制备工艺
CN113880844B (zh) * 2021-09-29 2023-02-14 武汉九州钰民医药科技有限公司 Wee1蛋白激酶抑制剂adavosertib的化学合成方法
WO2023072301A1 (zh) * 2021-11-01 2023-05-04 正大天晴药业集团股份有限公司 吡唑[3,4-d]嘧啶-3-酮类化合物及其医药用途
CN116462687A (zh) * 2022-01-18 2023-07-21 江苏天士力帝益药业有限公司 Wee1抑制剂及其制备和用途
CN116836184A (zh) * 2022-03-25 2023-10-03 药雅科技(上海)有限公司 Wee1激酶抑制剂的制备及其应用
CN115073460B (zh) * 2022-07-13 2023-07-25 苏州施安鼎泰生物医药技术有限公司 一种嘧啶并[5,4-c][2,6]萘啶衍生物及其制备方法以及药物组合物和应用
TW202404977A (zh) * 2022-07-15 2024-02-01 大陸商映恩生物製藥（蘇州）有限公司 一種嘧啶并五員雜環化合物、其製備方法和用途

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