DK2081551T3 - Formation of a dried reconstituted vesicle for pharmaceutical use - Google Patents
Formation of a dried reconstituted vesicle for pharmaceutical useInfo
- Publication number
- DK2081551T3 DK2081551T3 DK07818735.8T DK07818735T DK2081551T3 DK 2081551 T3 DK2081551 T3 DK 2081551T3 DK 07818735 T DK07818735 T DK 07818735T DK 2081551 T3 DK2081551 T3 DK 2081551T3
- Authority
- DK
- Denmark
- Prior art keywords
- formation
- pharmaceutical use
- dried reconstituted
- vesicle
- reconstituted vesicle
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06021093 | 2006-10-06 | ||
PCT/EP2007/008659 WO2008040556A1 (en) | 2006-10-06 | 2007-10-05 | Dried reconstituted vesicle formation for pharmaceutical application |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2081551T3 true DK2081551T3 (en) | 2013-05-06 |
Family
ID=38910893
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07818735.8T DK2081551T3 (en) | 2006-10-06 | 2007-10-05 | Formation of a dried reconstituted vesicle for pharmaceutical use |
Country Status (17)
Country | Link |
---|---|
US (3) | US9526761B2 (en) |
EP (2) | EP2081551B1 (en) |
JP (2) | JP5484059B2 (en) |
KR (1) | KR101333279B1 (en) |
CN (3) | CN101528197B (en) |
CA (1) | CA2664637C (en) |
CY (1) | CY1113934T1 (en) |
DK (1) | DK2081551T3 (en) |
ES (2) | ES2708851T3 (en) |
HR (1) | HRP20130328T1 (en) |
PL (1) | PL2081551T3 (en) |
PT (1) | PT2081551E (en) |
RS (1) | RS52706B (en) |
RU (1) | RU2443412C2 (en) |
SI (1) | SI2081551T1 (en) |
TW (1) | TWI455731B (en) |
WO (2) | WO2008040556A1 (en) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
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US6907884B2 (en) | 2002-09-30 | 2005-06-21 | Depay Acromed, Inc. | Method of straddling an intraosseous nerve |
US8361067B2 (en) | 2002-09-30 | 2013-01-29 | Relievant Medsystems, Inc. | Methods of therapeutically heating a vertebral body to treat back pain |
US7258690B2 (en) | 2003-03-28 | 2007-08-21 | Relievant Medsystems, Inc. | Windowed thermal ablation probe |
US7879103B2 (en) | 2005-04-15 | 2011-02-01 | Musculoskeletal Transplant Foundation | Vertebral disc repair |
WO2008013763A2 (en) | 2006-07-25 | 2008-01-31 | Musculoskeletal Transplant Foundation | Packed demineralized cancellous tissue forms for disc nucleus augmentation, restoration, or replacement and methods of implantation |
US10028753B2 (en) | 2008-09-26 | 2018-07-24 | Relievant Medsystems, Inc. | Spine treatment kits |
JP5688022B2 (en) | 2008-09-26 | 2015-03-25 | リリーバント メドシステムズ、インコーポレイテッド | System and method for guiding an instrument through the interior of a bone |
AU2011247659B2 (en) * | 2010-04-27 | 2014-07-24 | Scil Technology Gmbh | Stable aqueous MIA/CD-RAP formulations |
AU2012362524B2 (en) | 2011-12-30 | 2018-12-13 | Relievant Medsystems, Inc. | Systems and methods for treating back pain |
US20130202682A1 (en) * | 2012-01-24 | 2013-08-08 | The Trustees Of Columbia University In The City Of New York | Synthetic matrix vesicles for biomimetic mineralization |
NZ703532A (en) * | 2012-07-05 | 2018-02-23 | Taiwan Liposome Co Ltd | Methods of treating arthritis |
US10588691B2 (en) | 2012-09-12 | 2020-03-17 | Relievant Medsystems, Inc. | Radiofrequency ablation of tissue within a vertebral body |
IL238516B (en) | 2012-11-05 | 2022-08-01 | Relievant Medsystems Inc | System and methods for creating curved paths through bone and modulating nerves within the bone |
US9724151B2 (en) | 2013-08-08 | 2017-08-08 | Relievant Medsystems, Inc. | Modulating nerves within bone using bone fasteners |
US8986732B2 (en) | 2013-08-12 | 2015-03-24 | Helix Biopharma Corporation | Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery |
US10159646B2 (en) * | 2013-08-12 | 2018-12-25 | Altum-Avro Pharma Partnership | Biphasic lipid-vesicle compositions and methods for treating cervical dysplasia by intravaginal delivery |
BR112017011258B1 (en) * | 2014-12-18 | 2024-02-06 | Bracco Suisse S.A | AQUEOUS SUSPENSION OF MICROVESCLES FILLED WITH GAS AND PHARMACEUTICAL KIT |
US11376218B2 (en) | 2015-05-04 | 2022-07-05 | Versantis AG | Method for preparing transmembrane pH-gradient vesicles |
AU2016321884B2 (en) * | 2015-09-18 | 2021-01-07 | Bionet Pharma Gmbh | Improvement of expression and folding in the manufacturing process of CD-RAP by using a CD-RAP precursor protein |
CA3019751A1 (en) * | 2016-04-04 | 2017-10-12 | Gu Ventures Ab | Methods and compositions for the treatment of intervertebral disc herniation |
EP3618836A4 (en) * | 2017-04-25 | 2021-01-13 | Adjuvance Technologies, Inc. | Triterpene saponin analogues |
PT3675816T (en) * | 2017-08-28 | 2023-05-31 | Taiwan Liposome Co Ltd | Sustained-release anesthetic compositions and methods of preparation thereof |
US11389405B2 (en) | 2017-09-18 | 2022-07-19 | North Carolina State University | Artificial beta cells and methods of use thereof |
KR102649069B1 (en) | 2018-05-31 | 2024-03-19 | 주식회사 엑소코바이오 | Composition for improving face redness comprising an exosome derived from stem cell as an active ingredient |
KR102058961B1 (en) | 2018-07-28 | 2019-12-24 | 주식회사 엑소코바이오 | Method for freeze-drying exosomes |
KR102163806B1 (en) * | 2018-07-30 | 2020-10-07 | 주식회사 엑소코바이오 | Composition for reducing sebum release comprising an exosome derived from stem cell as an active ingredient |
RS65449B1 (en) * | 2018-10-09 | 2024-05-31 | Univ British Columbia | Compositions and systems comprising transfection-competent vesicles free of organic-solvents and detergents and methods related there to |
AU2020346827A1 (en) | 2019-09-12 | 2022-03-31 | Relievant Medsystems, Inc. | Systems and methods for tissue modulation |
US12082876B1 (en) | 2020-09-28 | 2024-09-10 | Relievant Medsystems, Inc. | Introducer drill |
JP2024505335A (en) | 2020-12-22 | 2024-02-06 | リリーバント メドシステムズ、インコーポレイテッド | Prediction of spinal neuromodulation candidates |
CN113995852B (en) * | 2021-11-08 | 2024-01-30 | 河北大学 | Arg-liposome microcapsule, microencapsulated protamine-siRNA complex, and preparation method and application thereof |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH621479A5 (en) * | 1977-08-05 | 1981-02-13 | Battelle Memorial Institute | |
FR2416008A1 (en) * | 1978-02-02 | 1979-08-31 | Oreal | LIPOSOME LYOPHILISATES |
IL79114A (en) * | 1985-08-07 | 1990-09-17 | Allergan Pharma | Method and composition for making liposomes |
FR2591105B1 (en) * | 1985-12-11 | 1989-03-24 | Moet Hennessy Rech | PHARMACEUTICAL COMPOSITION, IN PARTICULAR DERMATOLOGICAL, OR COSMETIC, BASED ON HYDRATED LIPID LAMELLAR PHASES OR LIPOSOMES CONTAINING A RETINOIDE OR A STRUCTURAL ANALOG OF SUCH A RETINOID AS A CAROTENOID. |
US4897353A (en) * | 1986-03-13 | 1990-01-30 | University Of Southwestern Louisiana | Cryogenic protection of phosphofructokinase using amino acids and zinc ions |
US5709879A (en) * | 1990-06-29 | 1998-01-20 | Chiron Corporation | Vaccine compositions containing liposomes |
AU8329391A (en) * | 1990-08-08 | 1992-03-02 | Liposome Technology, Inc. | Stable doxorubicin/liposome composition |
CA2120197A1 (en) * | 1993-04-02 | 1994-10-03 | Kenji Endo | Stable aqueous dispersions containing liposomes |
GB9320668D0 (en) * | 1993-10-07 | 1993-11-24 | Secr Defence | Liposomes containing particulare materials |
US6066331A (en) * | 1994-07-08 | 2000-05-23 | Barenholz; Yechezkel | Method for preparation of vesicles loaded with biological structures, biopolymers and/or oligomers |
IL115199A (en) | 1995-09-07 | 2005-05-17 | Opperbas Holding Bv | Composition comprising a polynucleic acid molecule in a liposome and method using said composition |
US6287590B1 (en) * | 1997-10-02 | 2001-09-11 | Esperion Therapeutics, Inc. | Peptide/lipid complex formation by co-lyophilization |
WO2000012762A1 (en) * | 1998-09-01 | 2000-03-09 | Millennium Pharmaceuticals, Inc. | A novel protein related to melanoma-inhibiting protein and uses thereof |
EP1025871A1 (en) * | 1999-01-28 | 2000-08-09 | F. Hoffmann-La Roche Ag | Use of a melanoma inhibiting activity factor (MIA) for cartilage and bone repair |
US7435260B2 (en) * | 1999-08-13 | 2008-10-14 | Ferree Bret A | Use of morphogenetic proteins to treat human disc disease |
CA2392721C (en) * | 1999-12-06 | 2009-01-20 | Sdgi Holdings, Inc. | Intervertebral disc treatment devices and methods |
EP1432403B1 (en) * | 2001-10-03 | 2010-07-28 | Celator Pharmaceuticals, Inc. | Liposome loading with metal ions |
EP1513853A2 (en) * | 2002-05-24 | 2005-03-16 | Neopharm, Inc. | Cardiolipin compositions, methods of preparation and use |
US7169405B2 (en) * | 2003-08-06 | 2007-01-30 | Warsaw Orthopedic, Inc. | Methods and devices for the treatment of intervertebral discs |
GB2430368B (en) * | 2004-03-30 | 2009-08-26 | Ilypsa Inc | Methods and compositions for treatment of ion imbalances |
ZA200610272B (en) * | 2004-05-21 | 2008-07-30 | Synthes Gmbh | Replacement of nucleus pulposus using a hydrogel |
JP5201987B2 (en) * | 2004-05-25 | 2013-06-05 | ストライカー コーポレイション | Use of morphogenic proteins to treat cartilage defects |
EP1604693A1 (en) * | 2004-06-09 | 2005-12-14 | Scil Technology GmbH | In situ forming scaffold, its manufacturing and use |
JP2008518951A (en) * | 2004-10-28 | 2008-06-05 | アルザ コーポレイション | Lyophilized liposome formulations and methods |
US20110071056A1 (en) * | 2009-09-24 | 2011-03-24 | Rajesh K Saini | Degradable Surfactants, Including Degradable Gemini Surfactants, and Associated Methods |
-
2007
- 2007-10-05 EP EP07818735A patent/EP2081551B1/en active Active
- 2007-10-05 PL PL07818735T patent/PL2081551T3/en unknown
- 2007-10-05 CN CN2007800397245A patent/CN101528197B/en not_active Expired - Fee Related
- 2007-10-05 CN CN2012104557068A patent/CN102940878A/en active Pending
- 2007-10-05 ES ES07818736T patent/ES2708851T3/en active Active
- 2007-10-05 CN CNA2007800422016A patent/CN101605534A/en active Pending
- 2007-10-05 DK DK07818735.8T patent/DK2081551T3/en active
- 2007-10-05 EP EP07818736.6A patent/EP2086507B1/en not_active Not-in-force
- 2007-10-05 WO PCT/EP2007/008659 patent/WO2008040556A1/en active Application Filing
- 2007-10-05 KR KR1020097009193A patent/KR101333279B1/en active IP Right Grant
- 2007-10-05 JP JP2009530811A patent/JP5484059B2/en not_active Expired - Fee Related
- 2007-10-05 SI SI200731193T patent/SI2081551T1/en unknown
- 2007-10-05 TW TW096137658A patent/TWI455731B/en not_active IP Right Cessation
- 2007-10-05 PT PT78187358T patent/PT2081551E/en unknown
- 2007-10-05 ES ES07818735T patent/ES2400162T3/en active Active
- 2007-10-05 JP JP2009530810A patent/JP5404402B2/en not_active Expired - Fee Related
- 2007-10-05 RS RS20130131A patent/RS52706B/en unknown
- 2007-10-05 WO PCT/EP2007/008660 patent/WO2008040557A1/en active Application Filing
- 2007-10-05 CA CA2664637A patent/CA2664637C/en not_active Expired - Fee Related
- 2007-10-05 RU RU2009117170/15A patent/RU2443412C2/en not_active IP Right Cessation
-
2009
- 2009-04-06 US US12/419,167 patent/US9526761B2/en not_active Expired - Fee Related
- 2009-04-06 US US12/419,131 patent/US20090297580A1/en not_active Abandoned
-
2013
- 2013-04-10 HR HRP20130328TT patent/HRP20130328T1/en unknown
- 2013-04-18 CY CY20131100316T patent/CY1113934T1/en unknown
-
2016
- 2016-03-08 US US15/064,444 patent/US20160220638A1/en not_active Abandoned
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