DK1915993T3 - Synergistiske kombinationer omfattende en renininhibitor til hjertekarsygdomme - Google Patents

Synergistiske kombinationer omfattende en renininhibitor til hjertekarsygdomme

Info

Publication number: DK1915993T3
Authority: DK; Denmark
Prior art keywords: renin inhibitor; cardiovascular disease; synergistic combinations; pharmaceutically acceptable; acceptable salt
Prior art date: 2000-11-17

Application number

DK08002401T

Other languages

English (en)

Inventor

William Hewitt

Daniel Lucius Vasella

Randy Lee Webb

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-11-17

Filing date

2001-11-15

Publication date

2013-10-14

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9903412&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1915993(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-11-15 Application filed by Novartis Ag filed Critical Novartis Ag

2013-10-14 Application granted granted Critical

2013-10-14 Publication of DK1915993T3 publication Critical patent/DK1915993T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Endocrinology (AREA)
Obesity (AREA)
Physical Education & Sports Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Rheumatology (AREA)
Toxicology (AREA)
Biomedical Technology (AREA)
Hospice & Palliative Care (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Emergency Medicine (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)

DK08002401T 2000-11-17 2001-11-15 Synergistiske kombinationer omfattende en renininhibitor til hjertekarsygdomme DK1915993T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0028151A GB0028151D0 (en)	2000-11-17	2000-11-17	Combination of organic compounds
EP20050015603 EP1602370B1 (en)	2000-11-17	2001-11-15	Synergistic combinations comprising a renin inhibitor for cardiovascular diseases

Publications (1)

Publication Number	Publication Date
DK1915993T3 true DK1915993T3 (da)	2013-10-14

Family

ID=9903412

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DK05015603T DK1602370T3 (da)	2000-11-17	2001-11-15	Synergistiske kombinationer omfattende en renininhibitor til hjerte-kredslöbs-sygdomme
DK01996377T DK1341533T3 (da)	2000-11-17	2001-11-15	Synergistiske kombinationer omfattende en renininhibitor til cardiovaskulære sygdomme
DK08002401T DK1915993T3 (da)	2000-11-17	2001-11-15	Synergistiske kombinationer omfattende en renininhibitor til hjertekarsygdomme

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DK05015603T DK1602370T3 (da)	2000-11-17	2001-11-15	Synergistiske kombinationer omfattende en renininhibitor til hjerte-kredslöbs-sygdomme
DK01996377T DK1341533T3 (da)	2000-11-17	2001-11-15	Synergistiske kombinationer omfattende en renininhibitor til cardiovaskulære sygdomme

Country Status (32)

Country	Link
US (4)	US8168616B1 (da)
EP (7)	EP2305232B1 (da)
JP (6)	JP2004513920A (da)
KR (6)	KR101008752B1 (da)
CN (4)	CN101091703A (da)
AT (2)	ATE317692T1 (da)
AU (2)	AU2002223680B2 (da)
BR (1)	BR0115411A (da)
CA (2)	CA2763223A1 (da)
CY (5)	CY1105603T1 (da)
CZ (2)	CZ305341B6 (da)
DE (3)	DE60117295T2 (da)
DK (3)	DK1602370T3 (da)
EC (1)	ECSP034603A (da)
ES (4)	ES2308347T3 (da)
GB (1)	GB0028151D0 (da)
HK (3)	HK1115544A1 (da)
HU (2)	HUP0301841A3 (da)
IL (3)	IL155707A (da)
LU (2)	LU91563I2 (da)
MX (1)	MXPA03004358A (da)
NL (2)	NL300385I1 (da)
NO (2)	NO334002B1 (da)
NZ (6)	NZ550897A (da)
PL (3)	PL400914A1 (da)
PT (3)	PT1915993E (da)
RU (2)	RU2310443C2 (da)
SG (1)	SG135969A1 (da)
SI (3)	SI1915993T1 (da)
SK (1)	SK287881B6 (da)
WO (1)	WO2002040007A1 (da)
ZA (1)	ZA200303497B (da)

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GB0612540D0 (en)	2006-06-23	2006-08-02	Novartis Ag	Galenical formulations of organic compounds
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2000
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Also Published As

Publication number	Publication date
HK1115544A1 (en)	2008-12-05
DE60117295T2 (de)	2006-08-17
DE122009000021I1 (de)	2009-08-06
IL155707A0 (en)	2003-11-23
CA2428647A1 (en)	2002-05-23
KR20030051753A (ko)	2003-06-25
DE60134349D1 (de)	2008-07-17
EP2305232B1 (en)	2019-07-17
WO2002040007A1 (en)	2002-05-23
US8618174B2 (en)	2013-12-31
CY1114829T1 (el)	2015-11-04
JP2009235107A (ja)	2009-10-15
IL212075A0 (en)	2011-06-30
JP6577994B2 (ja)	2019-09-18
JP2013213061A (ja)	2013-10-17
NZ550896A (en)	2008-06-30
PT1915993E (pt)	2013-10-14
PT1602370E (pt)	2008-09-10
HK1059212A1 (en)	2004-06-25
KR101258365B1 (ko)	2013-04-30
CA2763223A1 (en)	2002-05-23
SI1602370T1 (sl)	2008-10-31
HK1089356A1 (en)	2006-12-01
BR0115411A (pt)	2004-08-17
EP1602370B1 (en)	2008-06-04
HUP0301841A3 (en)	2010-07-28
HU230882B1 (hu)	2018-11-29
KR20080011355A (ko)	2008-02-01
DK1602370T3 (da)	2008-09-22
GB0028151D0 (en)	2001-01-03
ES2429292T3 (es)	2013-11-14
HU1400409D0 (hu)	2003-09-29
LU91563I2 (fr)	2009-07-06
KR20110063596A (ko)	2011-06-10
SK287881B6 (sk)	2012-02-03
MXPA03004358A (es)	2003-08-19
KR20100114904A (ko)	2010-10-26
NO20032233D0 (no)	2003-05-16
EP1915993B1 (en)	2013-07-10
KR101008752B1 (ko)	2011-01-14
ATE397445T1 (de)	2008-06-15
NL300385I1 (nl)	2009-07-01
EP2305233A1 (en)	2011-04-06
SI1341533T1 (sl)	2006-08-31
IL155707A (en)	2012-02-29
PL400915A1 (pl)	2012-12-17
KR20080097488A (ko)	2008-11-05
NO334002B1 (no)	2013-11-11
PL400914A1 (pl)	2012-12-17
ATE317692T1 (de)	2006-03-15
EP1915993A1 (en)	2008-04-30
PL361404A1 (en)	2004-10-04
NO2013019I1 (no)	2014-06-02
EP1930000A1 (en)	2008-06-11
JP2018030894A (ja)	2018-03-01
CN100404024C (zh)	2008-07-23
NZ525795A (en)	2005-03-24
AU2002223680B2 (en)	2005-04-07
NO20032233L (no)	2003-05-16
HUP0301841A2 (hu)	2003-09-29
RU2006132668A (ru)	2008-03-20
JP6089278B2 (ja)	2017-03-08
CY2009005I2 (el)	2012-01-25
CY2013045I2 (el)	2015-11-04
CZ299749B6 (cs)	2008-11-12
SI1915993T1 (sl)	2013-10-30
NZ550898A (en)	2008-07-31
CY1108305T1 (el)	2012-01-25
CY1105603T1 (el)	2010-07-28
EP2305231A1 (en)	2011-04-06
CY2013045I1 (el)	2015-11-04
ES2734523T3 (es)	2019-12-10
CY2009005I1 (el)	2012-01-25
US20120010295A1 (en)	2012-01-12
AU2368002A (en)	2002-05-27
JP2017019876A (ja)	2017-01-26
US9023894B2 (en)	2015-05-05
EP1341533B1 (en)	2006-02-15
EP2305232A1 (en)	2011-04-06
CN1474690A (zh)	2004-02-11
ZA200303497B (en)	2004-04-28
LU92315I2 (fr)	2014-01-27
ECSP034603A (es)	2003-06-25
RU2310443C2 (ru)	2007-11-20
RU2346703C2 (ru)	2009-02-20
US20120004312A1 (en)	2012-01-05
JP6603757B2 (ja)	2019-11-06
CN101264072A (zh)	2008-09-17
US9023893B2 (en)	2015-05-05
KR20080096715A (ko)	2008-10-31
NZ550897A (en)	2008-03-28
SK5842003A3 (en)	2003-11-04
JP6373931B2 (ja)	2018-08-15
ES2308347T3 (es)	2008-12-01
NO2013019I2 (no)	2013-12-17
DE60117295D1 (de)	2006-04-20
IL217847A0 (en)	2012-03-29
PL227576B1 (pl)	2017-12-29
EP1602370A2 (en)	2005-12-07
SG135969A1 (en)	2007-10-29
NL301005I2 (nl)	2019-10-29
IL212075A (en)	2013-08-29
CZ305341B6 (cs)	2015-08-05
DK1341533T3 (da)	2006-05-08
US20120016035A1 (en)	2012-01-19
CN101264073A (zh)	2008-09-17
PT1341533E (pt)	2006-06-30
JP2004513920A (ja)	2004-05-13
EP1341533A1 (en)	2003-09-10
ES2256335T3 (es)	2006-07-16
EP1602370A3 (en)	2005-12-14
NL301005I1 (da)	2019-09-10
US8168616B1 (en)	2012-05-01
CN101091703A (zh)	2007-12-26
NZ537691A (en)	2007-01-26
NZ568764A (en)	2009-11-27
JP2018131465A (ja)	2018-08-23

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BR0212042A (pt)	2004-08-17	Composto, composição farmacêutica, método de tratamento ou prevenção de doenças, e, uso de um composto
EP1734041A3 (en)	2007-01-24	Platelet ADP receptor inhibitors
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WO2004048381A3 (en)	2004-08-05	Pyrazoloazepine compounds as pharmaceutical agents
ITMI931806A0 (it)	1993-08-06	Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica , loro uso e composizioni farmaceutiche che li contengono
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ITTO20001109A0 (it)	2000-11-27	Composizione farmaceutica per il trattamento anti m. ulcerans.
RU2000128859A (ru)	2003-08-27	Способ защиты печени от ксенобиотиков в эксперименте
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