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DK1973946T3 - Translokation og mutant ros kinase i human ikke-småcellet lungekarcinom - Google Patents

Translokation og mutant ros kinase i human ikke-småcellet lungekarcinom

Info

Publication number
DK1973946T3
DK1973946T3 DK07718104.8T DK07718104T DK1973946T3 DK 1973946 T3 DK1973946 T3 DK 1973946T3 DK 07718104 T DK07718104 T DK 07718104T DK 1973946 T3 DK1973946 T3 DK 1973946T3
Authority
DK
Denmark
Prior art keywords
lungcarcinom
translocation
rose
mutant
kinase
Prior art date
Application number
DK07718104.8T
Other languages
English (en)
Inventor
Ailan Guo
Anthony Possemato
Original Assignee
Cell Signaling Technology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38288244&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1973946(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cell Signaling Technology Inc filed Critical Cell Signaling Technology Inc
Application granted granted Critical
Publication of DK1973946T3 publication Critical patent/DK1973946T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
DK07718104.8T 2006-01-20 2007-01-19 Translokation og mutant ros kinase i human ikke-småcellet lungekarcinom DK1973946T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76063406P 2006-01-20 2006-01-20
PCT/US2007/001360 WO2007084631A2 (en) 2006-01-20 2007-01-19 Translocation and mutant ros kinase in human non-small cell lung carcinoma

Publications (1)

Publication Number Publication Date
DK1973946T3 true DK1973946T3 (da) 2015-06-22

Family

ID=38288244

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07718104.8T DK1973946T3 (da) 2006-01-20 2007-01-19 Translokation og mutant ros kinase i human ikke-småcellet lungekarcinom
DK13176525.7T DK2671954T3 (da) 2006-01-20 2007-01-19 Translokation og mutant ROS-kinase i human ikke-småcellet lungekarcinom

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK13176525.7T DK2671954T3 (da) 2006-01-20 2007-01-19 Translokation og mutant ROS-kinase i human ikke-småcellet lungekarcinom

Country Status (10)

Country Link
EP (4) EP2671954B1 (da)
JP (7) JP5554925B2 (da)
CN (2) CN103981198B (da)
DK (2) DK1973946T3 (da)
ES (2) ES2539830T3 (da)
HK (2) HK1120272A1 (da)
HU (1) HUE039085T2 (da)
PT (1) PT2671954T (da)
SI (1) SI2671954T1 (da)
WO (1) WO2007084631A2 (da)

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US8383799B2 (en) 2006-01-20 2013-02-26 Cell Signaling Technology, Inc. Translocation and mutant ROS kinase in human non-small cell lung carcinoma
WO2007084631A2 (en) * 2006-01-20 2007-07-26 Cell Signaling Technology, Inc. Translocation and mutant ros kinase in human non-small cell lung carcinoma
US20120208824A1 (en) 2006-01-20 2012-08-16 Cell Signaling Technology, Inc. ROS Kinase in Lung Cancer
CA2702686C (en) * 2007-10-18 2023-04-04 Cell Signaling Technology, Inc. Translocation and mutant ros kinase in human non-small cell lung carcinoma
CA2744236C (en) 2009-02-12 2021-03-16 Cell Signaling Technology, Inc. Mutant ros expression in human cancer
US9109259B2 (en) 2010-06-22 2015-08-18 Japanese Foundation For Cancer Research Detection method for novel ROS1 fusions
KR20140041906A (ko) 2011-08-02 2014-04-04 화이자 인코포레이티드 암의 치료에 사용하기 위한 크리조티닙
CN104364391A (zh) * 2012-02-08 2015-02-18 因赛特遗传学公司 用于诊断和治疗癌症的涉及ros1融合的方法和组合物
WO2015075196A1 (en) * 2013-11-21 2015-05-28 Assistance Publique - Hopitaux De Paris Method for detecting chromosomal rearrangements
CN107236818A (zh) * 2017-07-19 2017-10-10 臻悦生物科技江苏有限公司 肺癌临床用药突变基因检测试剂盒
US11802315B2 (en) * 2017-08-09 2023-10-31 Pamgene B.V. Method for predicting the response of non-small-cell lung carcinoma patients to a medicament
CN108148912B (zh) * 2018-03-08 2021-10-08 四川大学 肿瘤的生物标志物、应用和肿瘤检测试剂盒
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Also Published As

Publication number Publication date
JP7262214B2 (ja) 2023-04-21
JP6957546B2 (ja) 2021-11-02
EP1973946B1 (en) 2015-03-25
JP2014140371A (ja) 2014-08-07
EP2671954A2 (en) 2013-12-11
EP3936621A1 (en) 2022-01-12
JP2009523446A (ja) 2009-06-25
JP2017070286A (ja) 2017-04-13
JP2021006039A (ja) 2021-01-21
JP2023039988A (ja) 2023-03-22
PT2671954T (pt) 2018-10-08
EP2671954B1 (en) 2018-05-16
WO2007084631A2 (en) 2007-07-26
CN101528921A (zh) 2009-09-09
HUE039085T2 (hu) 2018-12-28
JP2019141060A (ja) 2019-08-29
HK1256305A1 (zh) 2019-09-20
CN103981198A (zh) 2014-08-13
SI2671954T1 (sl) 2018-11-30
EP1973946A2 (en) 2008-10-01
JP5554925B2 (ja) 2014-07-23
CN103981198B (zh) 2020-09-01
ES2539830T3 (es) 2015-07-06
EP2671954A3 (en) 2014-02-12
EP1973946A4 (en) 2010-08-11
HK1120272A1 (en) 2009-03-27
DK2671954T3 (da) 2018-08-13
ES2683846T3 (es) 2018-09-28
JP2019068816A (ja) 2019-05-09
JP6521928B2 (ja) 2019-05-29
CN101528921B (zh) 2013-11-20
JP6259320B2 (ja) 2018-01-10
EP3360965A1 (en) 2018-08-15
WO2007084631A3 (en) 2008-12-31

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