DK1899325T3 - Imidazolinon- og hydantoinderivater som hidtil ukendte hæmmere af histondeacetylase - Google Patents
Imidazolinon- og hydantoinderivater som hidtil ukendte hæmmere af histondeacetylaseInfo
- Publication number
- DK1899325T3 DK1899325T3 DK06763797.5T DK06763797T DK1899325T3 DK 1899325 T3 DK1899325 T3 DK 1899325T3 DK 06763797 T DK06763797 T DK 06763797T DK 1899325 T3 DK1899325 T3 DK 1899325T3
- Authority
- DK
- Denmark
- Prior art keywords
- histone deacetylase
- imidazolinone
- novel inhibitors
- hydantoin derivatives
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05105592 | 2005-06-23 | ||
| PCT/EP2006/063351 WO2006136553A1 (en) | 2005-06-23 | 2006-06-20 | Imidazolinone and hydantoine derivatives as novel inhibitors of histone deacetylase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1899325T3 true DK1899325T3 (da) | 2012-03-05 |
Family
ID=35115704
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK06763797.5T DK1899325T3 (da) | 2005-06-23 | 2006-06-20 | Imidazolinon- og hydantoinderivater som hidtil ukendte hæmmere af histondeacetylase |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20100160321A1 (da) |
| EP (1) | EP1899325B1 (da) |
| JP (1) | JP5047168B2 (da) |
| AT (1) | ATE533759T1 (da) |
| AU (1) | AU2006260961B2 (da) |
| CA (1) | CA2608929C (da) |
| DK (1) | DK1899325T3 (da) |
| ES (1) | ES2377446T3 (da) |
| WO (1) | WO2006136553A1 (da) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2476186C (en) | 2002-03-13 | 2011-07-19 | Janssen Pharmaceutica N.V. | Sulfonylamino-derivatives as novel inhibitors of histone deacetylase |
| OA12789A (en) * | 2002-03-13 | 2006-07-10 | Janssen Pharmaceutica Nv | Carbonylamino-derivatives as novel inhibitors of histone deacetylase. |
| PL208401B1 (pl) * | 2002-03-13 | 2011-04-29 | Janssen Pharmaceutica Nv | Pochodne piperazynylowe, piperydynylowe i morfolinylowe, sposób ich wytwarzania, kompozycja je zawierająca oraz ich zastosowanie |
| BR0308081A (pt) * | 2002-03-13 | 2004-12-21 | Janssen Pharmaceutica Nv | Inibidores de histona desacetilase |
| CA2572833C (en) | 2004-07-28 | 2013-04-09 | Janssen Pharmaceutica N.V. | Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase |
| UA86066C2 (ru) * | 2004-07-28 | 2009-03-25 | Янссен Фармацевтика Н.В. | Производные замещенного пропенилпиперазина как ингибиторы гистондеацетилазы |
| US8138198B2 (en) | 2005-05-18 | 2012-03-20 | Angibaud Patrick Rene | Substituted aminopropenyl piperidine or morpholine derivatives as novel inhibitors of histone deacetylase |
| DK1943232T3 (da) * | 2005-10-27 | 2011-08-29 | Janssen Pharmaceutica Nv | Kvadratsyrederivater som inhibitorer af histondeacetylase |
| JP5250967B2 (ja) * | 2005-11-30 | 2013-07-31 | 三菱化学株式会社 | 有機化合物、電荷輸送材料、電荷輸送材料用組成物および有機電界発光素子 |
| EP1956008B1 (en) * | 2005-11-30 | 2012-03-28 | Mitsubishi Chemical Corporation | Organic compound, charge-transporting material, composition for charge-transporting material and organic electroluminescent device |
| US8101616B2 (en) | 2006-01-19 | 2012-01-24 | Janssen Pharmaceutica N.V. | Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase |
| AU2007206948B2 (en) * | 2006-01-19 | 2012-08-23 | Janssen Pharmaceutica N.V. | Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase |
| WO2007082882A1 (en) | 2006-01-19 | 2007-07-26 | Janssen Pharmaceutica N.V. | Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase |
| PL1981874T3 (pl) | 2006-01-19 | 2009-10-30 | Janssen Pharmaceutica Nv | Pochodne aminofenylowe jako nowe inhibitory deacetylazy histonowej |
| CN101370790B (zh) | 2006-01-19 | 2015-10-21 | 詹森药业有限公司 | 作为组蛋白去乙酰化酶抑制剂的吡啶和嘧啶衍生物 |
| GB0619753D0 (en) * | 2006-10-06 | 2006-11-15 | Chroma Therapeutics Ltd | Enzyme inhibitors |
| CN101827840A (zh) * | 2007-10-16 | 2010-09-08 | 诺瓦提斯公司 | 用作npy y2受体调节剂的咪唑烷-2,4-二酮(乙内酰脲)衍生物 |
| JP2011500633A (ja) | 2007-10-16 | 2011-01-06 | ノバルティス アーゲー | ４−フェニル−５−オキソ−イミダゾール誘導体、その医薬組成物および使用 |
| WO2012149093A1 (en) * | 2011-04-26 | 2012-11-01 | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY OF ARMY | 2-guanidino-4-oxo-imidazoline derivatives as antimalarial agents, synthesis and methods of use thereof |
| KR101842645B1 (ko) * | 2012-04-12 | 2018-03-29 | 한국화학연구원 | 신규한 히드라진온이 치환된 피리미딘 유도체 및 그의 용도 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060058553A1 (en) * | 2002-02-07 | 2006-03-16 | Axys Pharmaceuticals, Inc. | Novel bicyclic hydroxamates as inhibitors of histone deacetylase |
| BR0308081A (pt) * | 2002-03-13 | 2004-12-21 | Janssen Pharmaceutica Nv | Inibidores de histona desacetilase |
| GB0209715D0 (en) * | 2002-04-27 | 2002-06-05 | Astrazeneca Ab | Chemical compounds |
-
2006
- 2006-06-20 JP JP2008517483A patent/JP5047168B2/ja active Active
- 2006-06-20 DK DK06763797.5T patent/DK1899325T3/da active
- 2006-06-20 EP EP06763797A patent/EP1899325B1/en active Active
- 2006-06-20 AT AT06763797T patent/ATE533759T1/de active
- 2006-06-20 CA CA2608929A patent/CA2608929C/en active Active
- 2006-06-20 AU AU2006260961A patent/AU2006260961B2/en not_active Ceased
- 2006-06-20 US US11/917,999 patent/US20100160321A1/en not_active Abandoned
- 2006-06-20 ES ES06763797T patent/ES2377446T3/es active Active
- 2006-06-20 WO PCT/EP2006/063351 patent/WO2006136553A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| EP1899325A1 (en) | 2008-03-19 |
| AU2006260961B2 (en) | 2011-08-11 |
| JP5047168B2 (ja) | 2012-10-10 |
| AU2006260961A1 (en) | 2006-12-28 |
| CA2608929C (en) | 2014-01-28 |
| EP1899325B1 (en) | 2011-11-16 |
| JP2008546737A (ja) | 2008-12-25 |
| ATE533759T1 (de) | 2011-12-15 |
| CA2608929A1 (en) | 2006-12-28 |
| WO2006136553A1 (en) | 2006-12-28 |
| ES2377446T3 (es) | 2012-03-27 |
| US20100160321A1 (en) | 2010-06-24 |
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