DK1869065T3 - Fremgangsmåde til kromatografi med svag opdeling - Google Patents
Fremgangsmåde til kromatografi med svag opdeling Download PDFInfo
- Publication number
- DK1869065T3 DK1869065T3 DK06738028.7T DK06738028T DK1869065T3 DK 1869065 T3 DK1869065 T3 DK 1869065T3 DK 06738028 T DK06738028 T DK 06738028T DK 1869065 T3 DK1869065 T3 DK 1869065T3
- Authority
- DK
- Denmark
- Prior art keywords
- partition chromatography
- weak partition
- weak
- chromatography
- partition
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
- 238000004810 partition chromatography Methods 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/30—Partition chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/32—Bonded phase chromatography
- B01D15/325—Reversed phase
- B01D15/327—Reversed phase with hydrophobic interaction
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
- B01D15/361—Ion-exchange
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- B01D15/3828—Ligand exchange chromatography, e.g. complexation, chelation or metal interaction chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66043705P | 2005-03-11 | 2005-03-11 | |
PCT/US2006/008919 WO2006099308A2 (en) | 2005-03-11 | 2006-03-10 | A method of weak partitioning chromatography |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1869065T3 true DK1869065T3 (da) | 2020-06-08 |
Family
ID=36992346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK06738028.7T DK1869065T3 (da) | 2005-03-11 | 2006-03-10 | Fremgangsmåde til kromatografi med svag opdeling |
Country Status (21)
Country | Link |
---|---|
US (3) | US8067182B2 (da) |
EP (1) | EP1869065B1 (da) |
JP (1) | JP5199063B2 (da) |
KR (2) | KR101482791B1 (da) |
CN (2) | CN101175765A (da) |
AU (1) | AU2006223180B2 (da) |
BR (1) | BRPI0608584B8 (da) |
CA (1) | CA2601062C (da) |
CR (1) | CR9377A (da) |
DK (1) | DK1869065T3 (da) |
ES (1) | ES2797480T3 (da) |
HK (1) | HK1210476A1 (da) |
HU (1) | HUE049797T2 (da) |
IL (1) | IL185687A (da) |
MX (1) | MX2007011129A (da) |
NO (1) | NO20074443L (da) |
PL (1) | PL1869065T3 (da) |
PT (1) | PT1869065T (da) |
RU (1) | RU2457214C2 (da) |
SI (1) | SI1869065T1 (da) |
WO (1) | WO2006099308A2 (da) |
Families Citing this family (68)
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KR101482791B1 (ko) * | 2005-03-11 | 2015-01-21 | 와이어쓰 엘엘씨 | 약한 분배성 크로마토그래피법 |
EP2069387A4 (en) * | 2006-06-14 | 2011-02-02 | Glaxosmithkline Llc | METHODS OF PURIFYING ANTIBODIES USING HYDROXYAPATITE CERAMIC |
JP2010501623A (ja) | 2006-08-28 | 2010-01-21 | アレス トレーディング ソシエテ アノニム | Fc含有タンパク質の精製法 |
TW200821026A (en) * | 2006-09-08 | 2008-05-16 | Wyeth Corp | Arginine wash in protein purification using affinity chromatography |
MY185887A (en) | 2006-09-13 | 2021-06-14 | Abbvie Inc | Cell culture improvements |
US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
CN104152395B (zh) * | 2006-11-08 | 2020-03-10 | 惠氏公司 | 合理设计的细胞培养基 |
SI2565206T1 (sl) * | 2007-10-30 | 2016-07-29 | Genentech, Inc. | Čiščenje protitelesa s kationsko izmenjevalno kromatografijo |
WO2009092010A1 (en) * | 2008-01-18 | 2009-07-23 | Gagnon Peter S | Enhanced purification of phosphorylated and non-phosphorylated biomolecules by apatite chromatography |
JP5666447B2 (ja) † | 2008-08-14 | 2015-02-12 | ジェネンテック, インコーポレイテッド | 常在性タンパク質置換イオン交換メンブレンクロマトグラフィを用いた混入物除去方法 |
US20100069617A1 (en) * | 2008-09-12 | 2010-03-18 | Ge Healthcare Bio-Sciences Ab | Enhanced protein aggregate removal by mixed mode chromatography on hydrophobic interaction media in the presence of protein-excluded zwitterions |
EP2326658A4 (en) * | 2008-09-12 | 2013-04-10 | Ge Healthcare Bio Sciences Ab | IMPROVED PROTEIN-AGGREGATE SEPARATION WITH MULTIMODAL ANION EXCHANGERS IN THE PRESENCE OF ZWITTERIONS EXCLUDED FROM THE PROTEIN |
CA2738499A1 (en) | 2008-10-20 | 2010-04-29 | Abbott Laboratories | Viral inactivation during purification of antibodies |
RU2520838C2 (ru) | 2008-10-20 | 2014-06-27 | Эббви Инк | Выделение и очистка антител с использованием аффинной хроматографии на основе белка а |
RU2481824C2 (ru) | 2008-10-29 | 2013-05-20 | Аблинкс Н.В | Препараты однодоменных антигенсвязывающих молекул |
US10118962B2 (en) | 2008-10-29 | 2018-11-06 | Ablynx N.V. | Methods for purification of single domain antigen binding molecules |
ES2488542T3 (es) | 2008-12-22 | 2014-08-27 | F. Hoffmann-La Roche Ag | Purificación de inmunoglobulinas |
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US9505833B2 (en) | 2012-04-20 | 2016-11-29 | Abbvie Inc. | Human antibodies that bind human TNF-alpha and methods of preparing the same |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
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KR20150027060A (ko) * | 2012-05-31 | 2015-03-11 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 다중 모드의 기능성들을 갖는 입자들로 면역글로불린 g 조제물들의 크로마토그래피 정제 |
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CA2542951C (en) | 2003-10-24 | 2016-08-30 | Abhinav A. Shukla | Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction |
JP5004586B2 (ja) * | 2003-10-27 | 2012-08-22 | ワイス・エルエルシー | ヒドロキシアパタイトクロマトグラフィーを用いる高分子量凝集体の取り出し |
KR101482791B1 (ko) * | 2005-03-11 | 2015-01-21 | 와이어쓰 엘엘씨 | 약한 분배성 크로마토그래피법 |
-
2006
- 2006-03-10 KR KR20077020848A patent/KR101482791B1/ko active IP Right Grant
- 2006-03-10 PL PL06738028T patent/PL1869065T3/pl unknown
- 2006-03-10 JP JP2008501028A patent/JP5199063B2/ja active Active
- 2006-03-10 PT PT67380287T patent/PT1869065T/pt unknown
- 2006-03-10 US US11/372,054 patent/US8067182B2/en active Active
- 2006-03-10 ES ES06738028T patent/ES2797480T3/es active Active
- 2006-03-10 BR BRPI0608584A patent/BRPI0608584B8/pt active IP Right Grant
- 2006-03-10 AU AU2006223180A patent/AU2006223180B2/en active Active
- 2006-03-10 DK DK06738028.7T patent/DK1869065T3/da active
- 2006-03-10 WO PCT/US2006/008919 patent/WO2006099308A2/en active Application Filing
- 2006-03-10 CN CNA200680016391XA patent/CN101175765A/zh active Pending
- 2006-03-10 HU HUE06738028A patent/HUE049797T2/hu unknown
- 2006-03-10 MX MX2007011129A patent/MX2007011129A/es active IP Right Grant
- 2006-03-10 SI SI200632376T patent/SI1869065T1/sl unknown
- 2006-03-10 KR KR1020137028820A patent/KR101660575B1/ko active IP Right Grant
- 2006-03-10 CA CA2601062A patent/CA2601062C/en active Active
- 2006-03-10 RU RU2007132851/10A patent/RU2457214C2/ru not_active Application Discontinuation
- 2006-03-10 EP EP06738028.7A patent/EP1869065B1/en active Active
- 2006-03-10 CN CN201410849296.4A patent/CN104610422A/zh active Pending
- 2006-08-28 US US11/510,634 patent/US20070054390A1/en not_active Abandoned
-
2007
- 2007-09-03 NO NO20074443A patent/NO20074443L/no not_active Application Discontinuation
- 2007-09-03 IL IL185687A patent/IL185687A/en active IP Right Grant
- 2007-09-12 CR CR9377A patent/CR9377A/es not_active Application Discontinuation
-
2011
- 2011-11-28 US US13/305,045 patent/US9144755B2/en active Active
-
2015
- 2015-11-12 HK HK15111155.1A patent/HK1210476A1/xx unknown
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