DK1632232T3 - Salt af 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimehtylphenyl]amino]-2-pyrimidinyl]-amino]-benzonitril - Google Patents

Salt af 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimehtylphenyl]amino]-2-pyrimidinyl]-amino]-benzonitril

Info

Publication number: DK1632232T3
Authority: DK; Denmark
Prior art keywords: amino; cyanoethenyl; benzonitrile; dimethylphenyl; pyrimidinyl
Prior art date: 2004-09-02

Application number

DK05108086.9T

Other languages

English (en)

Other versions

DK1632232T6 (da

Inventor

Paul Theodoor Agnes Stevens

Jozef Peeters

Roger Petrus Gerebern Vandecruys

Alfred Elisabeth Stappers

Alex Herman Copmans

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-09-02

Filing date

2005-09-02

Publication date

2011-08-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38091637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1632232(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-09-02 Priority claimed from MYPI20043578A external-priority patent/MY169670A/en

2005-09-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2011-08-22 Publication of DK1632232T3 publication Critical patent/DK1632232T3/da

2022-04-19 Application granted granted Critical

2022-04-19 Publication of DK1632232T6 publication Critical patent/DK1632232T6/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Virology (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
AIDS & HIV (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Tropical Medicine & Parasitology (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Hybrid Cells (AREA)

DK05108086.9T 2004-09-02 2005-09-02 Salt af 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]¬amino]¬benzonitril DK1632232T6 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
MYPI20043578A MY169670A (en)	2003-09-03	2004-09-02	Combinations of a pyrimidine containing nnrti with rt inhibitors
PCT/EP2004/052028 WO2005021001A1 (en)	2003-09-03	2004-09-03	Combinations of a pyrimidine containing nnrti with rt inhibitors
EP05101467		2005-02-25

Publications (2)

Publication Number	Publication Date
DK1632232T3 true DK1632232T3 (da)	2011-08-22
DK1632232T6 DK1632232T6 (da)	2022-04-19

Family

ID=38091637

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK05108086.9T DK1632232T6 (da)	2004-09-02	2005-09-02	Salt af 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]¬amino]¬benzonitril

Country Status (21)

Country	Link
EP (1)	EP1632232B3 (da)
JP (1)	JP4912309B2 (da)
CN (1)	CN104586850A (da)
AT (1)	ATE508748T1 (da)
BR (1)	BRPI0514871A (da)
CY (3)	CY1112249T1 (da)
DK (1)	DK1632232T6 (da)
EA (1)	EA013686B1 (da)
ES (1)	ES2371442T7 (da)
FR (2)	FR16C1023I1 (da)
HK (1)	HK1210029A1 (da)
HU (2)	HUS1600060I1 (da)
IL (1)	IL181650A (da)
LT (2)	LTPA2016042I1 (da)
ME (1)	ME01246B (da)
MX (1)	MX2007002595A (da)
NI (1)	NI200700068A (da)
NO (3)	NO340654B1 (da)
PT (1)	PT1632232E (da)
RS (1)	RS51923B2 (da)
SI (1)	SI1632232T1 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY169670A (en)	2003-09-03	2019-05-08	Tibotec Pharm Ltd	Combinations of a pyrimidine containing nnrti with rt inhibitors
UA96436C2 (ru)	2006-01-20	2011-11-10	Тиботек Фармасьютикелз Лтд.	Долгосрочное лечение вич-инфекции
AR065720A1 (es)	2007-03-14	2009-06-24	Tibotec Pharm Ltd	Polvos para reconstitucion que comprenden rilpivirina dispersos en ciertos polimeros. uso. proceso.
SG10201912527XA (en) *	2010-11-19	2020-02-27	Gilead Sciences Inc	Therapeutic compositions comprising rilpivirine hcl and tenofovir disoproxil fumarate
EA024409B1 (ru) *	2011-04-15	2016-09-30	Эмкьюар Фармасьютикалз Лимитед	Улучшенный способ получения промежуточного соединения для синтеза рилпивирина
EP2628732A1 (en) *	2012-02-20	2013-08-21	Sandoz AG	Novel crystalline form of rilpivirine hydrochloride
EP2604593A1 (en)	2011-12-14	2013-06-19	Sandoz AG	Polymorph of Rilpivirine hydrochloride and its use as antiviral
WO2013087794A1 (en)	2011-12-14	2013-06-20	Sandoz Ag	Polymorph of rilpivirine hydrochloride and its use as antiviral
WO2013153162A1 (en) *	2012-04-11	2013-10-17	Sandoz Ag	Polymorph of rilpivirine hydrochloride
WO2013153161A2 (en) *	2012-04-11	2013-10-17	Sandoz Ag	Novel polymorph of rilpivirine hydrochloride
CN103570688B (zh) *	2012-07-19	2016-06-08	中国科学院上海药物研究所	2，5-二氨甲基吡嗪类化合物、其药物组合物、制备方法和用途
GR1008965B (el) *	2015-12-02	2017-02-28	Φαρματεν Ανωνυμος Βιομηχανικη Και Εμπορικη Εταιρεια Φαρμακευτικων Ιατρικων Και Καλλυντικων Προϊοντων	Φαρμακευτικο σκευασμα που περιλαμβανει δαρουναβιρη και μεθοδος παρασκευης αυτου
RU2616267C1 (ru) *	2016-01-25	2017-04-13	Закрытое Акционерное Общество "БИОКОМ"	Твердая лекарственная форма индинавира немедленного высвобождения и способ ее получения
EP3528791B1 (en) *	2016-10-24	2023-12-06	Janssen Sciences Ireland Unlimited Company	Dispersible compositions
AU2018291076B2 (en) *	2017-06-30	2021-01-21	Janssen Sciences Ireland Unlimited Company	Combination and uses and treatments thereof
CN114392241B (zh) *	2022-01-10	2023-07-25	安徽贝克生物制药有限公司	一种利匹韦林片及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6307543B1 (en) *	1998-09-10	2001-10-23	Silicon Image, Inc.	Bi-directional data transfer using two pair of differential lines as a single additional differential pair
JO3429B1 (ar) *	2001-08-13	2019-10-20	Janssen Pharmaceutica Nv	مشتقات برميدينات مثبطة فيروس الايدز
MY169670A (en) *	2003-09-03	2019-05-08	Tibotec Pharm Ltd	Combinations of a pyrimidine containing nnrti with rt inhibitors
JP4822707B2 (ja) *	2002-08-09	2011-11-24	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	４−［［４−［［４−（２−シアノエテニル）−２，６−ジメチルフェニル］アミノ］−２−ピリミジニル］アミノ］ベンゾニトリルの製造方法
AU2002350719A1 (en) *	2002-11-29	2004-06-23	Janssen Pharmaceutica N.V.	Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
CL2004000192A1 (es) *	2003-02-07	2005-03-18	Janssen Pharmaceutica Nv	Uso de compuestos derivados de 2-aminopirimidina para preparar un medicamento para la prevencion de una infeccion por vih relaciones sexuales o un contacto intimo en la pareja.

2005
- 2005-09-02 ME MEP-2011-144A patent/ME01246B/me unknown
- 2005-09-02 JP JP2007528886A patent/JP4912309B2/ja active Active
- 2005-09-02 RS RS20110355A patent/RS51923B2/sr unknown
- 2005-09-02 ES ES05108086T patent/ES2371442T7/es active Active
- 2005-09-02 EP EP05108086.9A patent/EP1632232B3/en active Active
- 2005-09-02 BR BRPI0514871-5A patent/BRPI0514871A/pt not_active Application Discontinuation
- 2005-09-02 EA EA200700536A patent/EA013686B1/ru active Protection Beyond IP Right Term
- 2005-09-02 SI SI200531339T patent/SI1632232T1/sl unknown
- 2005-09-02 DK DK05108086.9T patent/DK1632232T6/da active
- 2005-09-02 MX MX2007002595A patent/MX2007002595A/es active IP Right Grant
- 2005-09-02 PT PT05108086T patent/PT1632232E/pt unknown
- 2005-09-02 CN CN201510012919.7A patent/CN104586850A/zh active Pending
- 2005-09-02 AT AT05108086T patent/ATE508748T1/de active
2007
- 2007-03-01 IL IL181650A patent/IL181650A/en active IP Right Grant
- 2007-03-01 NI NI200700068A patent/NI200700068A/es unknown
- 2007-04-02 NO NO20071745A patent/NO340654B1/no active Protection Beyond IP Right Term
2011
- 2011-08-10 CY CY20111100775T patent/CY1112249T1/el unknown
2015
- 2015-11-03 HK HK15110805.7A patent/HK1210029A1/xx unknown
2016
- 2016-12-20 CY CY2016051C patent/CY2016051I1/el unknown
- 2016-12-20 LT LTPA2016042C patent/LTPA2016042I1/lt unknown
- 2016-12-20 LT LTPA2016043C patent/LTPA2016043I1/lt unknown
- 2016-12-20 HU HUS1600060C patent/HUS1600060I1/hu unknown
- 2016-12-20 HU HUS1600061C patent/HUS1600061I1/hu unknown
- 2016-12-20 FR FR16C1023C patent/FR16C1023I1/fr active Active
- 2016-12-20 FR FR16C1025C patent/FR16C1025I1/fr active Active
- 2016-12-20 CY CY2016050C patent/CY2016050I1/el unknown
2017
- 2017-11-21 NO NO2017065C patent/NO2017065I1/no unknown
- 2017-11-21 NO NO2017063C patent/NO2017063I1/no unknown

Also Published As

Publication number	Publication date
EP1632232A1 (en)	2006-03-08
HUS1600061I1 (hu)	2017-01-30
ES2371442T3 (es)	2012-01-02
HK1210029A1 (en)	2016-04-15
NO2017063I1 (no)	2017-11-21
ATE508748T1 (de)	2011-05-15
EA013686B1 (ru)	2010-06-30
PT1632232E (pt)	2011-08-02
EP1632232B3 (en)	2022-03-30
HUS1600060I1 (hu)	2017-01-30
NO20071745L (no)	2007-04-02
JP4912309B2 (ja)	2012-04-11
BRPI0514871A (pt)	2008-06-24
EP1632232B1 (en)	2011-05-11
MX2007002595A (es)	2007-04-25
LTPA2016043I1 (lt)	2017-01-10
CN104586850A (zh)	2015-05-06
LTPA2016042I1 (lt)	2017-01-10
JP2008511592A (ja)	2008-04-17
CY2016051I1 (el)	2017-07-12
SI1632232T1 (sl)	2011-09-30
ME01246B (me)	2013-06-20
RS51923B2 (sr)	2022-05-31
ES2371442T7 (es)	2022-05-12
FR16C1025I1 (fr)	2017-02-03
NO2017065I1 (no)	2017-11-21
DK1632232T6 (da)	2022-04-19
CY2016050I1 (el)	2017-07-12
EA200700536A1 (ru)	2007-08-31
CY1112249T1 (el)	2015-12-09
RS51923B (en)	2012-02-29
NO340654B1 (no)	2017-05-22
NI200700068A (es)	2016-09-29
IL181650A0 (en)	2007-07-04
FR16C1023I1 (fr)	2017-02-03
IL181650A (en)	2012-08-30

Publication	Publication Date	Title
LTPA2016042I1 (lt)	2017-01-10	4[[4-[[4-(2-Cianoetenil)-2,6-dimetilfenil]amino]-2-pirimidinil]amino]benzonitrilo druska
ME00191B (me)	2010-10-10	Farmaceutske kompozicije koje obuhvataju inhibitor hmg reduktaze
HK1174922A1 (en)	2013-06-21	Processes for the preparation of 4-[[4-[[4-(2-cyanoethenyl)-2,6- dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile 4-[[4-[[4-(2-)-2,6-]]-2-]]
NO2014030I1 (no)	2015-01-05	(E)-4-[[4-[[4-(2-cyanoetenyl)-2,6-dimetylfenyl]-amino]-2-pyrimidinyl]-amino]-benzonitril("Rilpivirine") samt enhver terapeutisk form derav som er dekket av det aktuelle patentet så som farmasøytisk akseptable salter av Rilpivirie innbefattende hydrokloridsaltet av Rilpivirine, og emtricitabine.
WO2009007441A3 (en)	2009-04-30	Crystalline form of (e) 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2 pyrimidinyl]amino]benzonitrile
PL1632232T3 (pl)	2011-10-31	Sól 4-[[4-[[4-(2-cyjanoetenylo)-2,6-dimetylofenylo]amino]-2-pirymidynylo]amino]benzonitrylu
CR9032A (es)	2009-07-30	Fumarato de 4-((4-((4-(2-cianoetenil)-2,6-dimetilfenil)amino-2- pirimidinil)amino)benzonitrilo
UA92467C2 (ru)	2010-11-10	Гидрохлорид 4-[[4-[[4-(2-цианоэтенил)-2,6-диметилфенил]амино]-2-пиримидинил]амино]бензонитрила
AP2487A (en)	2012-10-03	Fumarate of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]-amino]-2-pyrimidinyl]amino]benzonitrile
HRP20110563T1 (en)	2011-09-30	Salt of 4[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile