DK162391C - Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser - Google Patents

Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser

Info

Publication number: DK162391C
Authority: DK; Denmark
Prior art keywords: cephem; disubstituted; isomers; carboxylic acid; acid compounds
Prior art date: 1976-04-12

Application number

DK075077A

Other languages

English (en)

Other versions

DK75077A (da

DK162391B (da

Inventor

Takao Takaya

Takashi Masugi

Hisashi Takasugi

Hiromu Kochi

Original Assignee

Fujisawa Pharmaceutical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-04-12

Filing date

1977-02-21

Publication date

1992-03-09

1976-04-12 Priority claimed from GB14916/76A external-priority patent/GB1576625A/en

1977-02-21 Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co

1977-10-13 Publication of DK75077A publication Critical patent/DK75077A/da

1991-10-21 Publication of DK162391B publication Critical patent/DK162391B/da

1992-03-09 Application granted granted Critical

1992-03-09 Publication of DK162391C publication Critical patent/DK162391C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/16—Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK075077A 1976-04-12 1977-02-21 Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser DK162391C (da)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
GB1491676		1976-04-12
GB14916/76A GB1576625A (en)	1976-04-12	1976-04-12	Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
GB2349076		1976-06-07
GB2349076		1976-06-07
JP12582676		1976-10-19
JP51125826A JPS5941995B2 (ja)	1976-04-12	1976-10-19	３，７−ジ置換−３−セフエム−４−カルボン酸化合物およびその塩類およびそれらの製造方法

Publications (3)

Publication Number	Publication Date
DK75077A DK75077A (da)	1977-10-13
DK162391B DK162391B (da)	1991-10-21
DK162391C true DK162391C (da)	1992-03-09

Family

ID=27257189

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK075077A DK162391C (da)	1976-04-12	1977-02-21	Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser

Country Status (13)

Country	Link
AR (2)	AR227864A1 (da)
AT (1)	AT358728B (da)
CA (1)	CA1337522C (da)
CH (2)	CH638532A5 (da)
DE (1)	DE2707565A1 (da)
DK (1)	DK162391C (da)
ES (7)	ES457191A1 (da)
FR (1)	FR2348219A1 (da)
HU (1)	HU177441B (da)
IE (1)	IE45597B1 (da)
MX (1)	MX4985E (da)
NL (1)	NL191259C (da)
SE (2)	SE443981B (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3192167A (en) *	1962-09-20	1965-06-29	Ogawa Abiko	Low pressure liquid vaporizer which is electrically heated
BE878514A (fr) *	1978-09-04	1980-02-29	Fujisawa Pharmaceutical Co	Procede de preparation de composes d'acide 3-cephem-4-carboxylique a disubstitution en positions 3 et 7, nouveaux produits ainsi obtenus et leur utilisation pour leur activite antibacterienne
GR63088B (en) *	1976-04-14	1979-08-09	Takeda Chemical Industries Ltd	Preparation process of novel cephalosporins
FR2381053A1 (fr) *	1977-02-18	1978-09-15	Roussel Uclaf	Nouvelles oximes derivees de l'acide 3-thiadiazolyl thiomethyl 7-aminothiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
PH17188A (en)	1977-03-14	1984-06-14	Fujisawa Pharmaceutical Co	New cephem and cepham compounds and their pharmaceutical compositions and method of use
FR2399418A1 (fr) *	1977-03-14	1979-03-02	Fujisawa Pharmaceutical Co	Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques
SE439312B (sv) *	1977-03-25	1985-06-10	Roussel Uclaf	Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
DE2714880A1 (de) *	1977-04-02	1978-10-26	Hoechst Ag	Cephemderivate und verfahren zu ihrer herstellung
JPS5498795A (en) *	1978-01-13	1979-08-03	Takeda Chem Ind Ltd	Cephalosporin derivative and its preparation
FR2432521A1 (fr) *	1978-03-31	1980-02-29	Roussel Uclaf	Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2553770B2 (fr) *	1978-03-31	1986-03-14	Roussel Uclaf	Nouveaux produits derives de l'acide 2(2-amino thiazol-4-yl) 2-alcoxy-imino acetique substitues sur l'oxime et leur procede de preparation
FR2421907A1 (fr) *	1978-04-07	1979-11-02	Roussel Uclaf	Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2438051A2 (fr) *	1978-10-05	1980-04-30	Roussel Uclaf	Nouvelles oximes derivees de l'acide 3-azidomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
MC1259A1 (fr)	1978-05-30	1980-01-14	Hoffmann La Roche	Derives acyles
US4284631A (en) *	1978-07-31	1981-08-18	Fujisawa Pharmaceutical Co., Ltd.	7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them
FR2453161A1 (fr) *	1978-08-31	1980-10-31	Fujisawa Pharmaceutical Co	Procede de preparation de derives d'acide thiazolylacetique et nouveaux produits ainsi obtenus
US4341775A (en) *	1978-09-11	1982-07-27	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds
DE2965943D1 (en) *	1978-10-17	1983-08-25	Fujisawa Pharmaceutical Co	Cepham compounds, pharmaceutical compositions containing them and processes for the preparation thereof and of known cephem compounds
DE2945248A1 (de) *	1978-11-13	1980-05-22	Fujisawa Pharmaceutical Co	Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
FR2448543A1 (fr) *	1979-02-09	1980-09-05	Roussel Uclaf	Nouvelles oximes o-substituees par un radical comportant un ammonium quaternaire et derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2461713A1 (fr) *	1979-07-19	1981-02-06	Roussel Uclaf	Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
FR2462439A1 (fr) *	1979-07-26	1981-02-13	Roussel Uclaf	Nouveau procede de preparation de produits derives de l'acide 7-/(2-aryl) 2-hydroxyimino acetamido/cephalosporanique
IL61458A0 (en) *	1979-12-07	1980-12-31	Erba Farmitalia	N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them
FR2506307A1 (fr) *	1981-05-22	1982-11-26	Roussel Uclaf	Nouveaux derives substitues de l'acide 2-(2-amino 4-thiazolyl) 2-hydroxyimino acetique et leur procede de preparation
US4426528A (en) *	1982-04-01	1984-01-17	Eli Lilly And Company	Purification of syn-(2-aminothiazol-4-yl)methoxyimino)acetic acid
FR2532936A1 (fr) *	1982-09-13	1984-03-16	Roussel Uclaf	Nouveaux derives de l'acide 2-amino-thiazolyl-4-yl acetique comportant une fonction oxime substituee et leur procede de preparation
GB8324152D0 (en) *	1983-09-09	1983-10-12	Glaxo Group Ltd	Chemical process
IT8448798A0 (it) *	1983-09-12	1984-09-05	Biochemie Gmbh	Procedimento per la preparazione di antibiotici del tipo cefalosporina
GB2161476B (en) *	1984-05-25	1988-01-27	Toyama Chemical Co Ltd	2-aminothiazolyl-2-methoxyimino acetamides and their use in preparing cephalosporins
EP0241901B1 (en) *	1986-04-14	1994-08-24	Banyu Pharmaceutical Co., Ltd.	Cephalosporin derivatives, processes for their preparation and antibacterial agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1399086A (en) *	1971-05-14	1975-06-25	Glaxo Lab Ltd	Cephalosporin compounds
NZ176206A (en) *	1973-12-25	1978-03-06	Takeda Chemical Industries Ltd	Cephalosporins
DK154939C (da) *	1974-12-19	1989-06-12	Takeda Chemical Industries Ltd	Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
SE432254B (sv) *	1975-02-04	1984-03-26	Fujisawa Pharmaceutical Co	Analogiforfarande for framstellning av 3-substituerade 7-(alfa,alfa-disubstituerade acetamido)-3-cefem-4-karboxylsyror
FR2346014A1 (fr) *	1976-01-23	1977-10-28	Roussel Uclaf	Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2760123C2 (de) *	1976-01-23	1986-04-30	Roussel-Uclaf, Paris	7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
SE440655B (sv) *	1976-01-23	1985-08-12	Roussel Uclaf	Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra
FR2345153A1 (fr) *	1976-03-25	1977-10-21	Roussel Uclaf	Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GR63088B (en) *	1976-04-14	1979-08-09	Takeda Chemical Industries Ltd	Preparation process of novel cephalosporins

1977
- 1977-02-21 DK DK075077A patent/DK162391C/da active
- 1977-02-22 SE SE7701964A patent/SE443981B/xx not_active IP Right Cessation
- 1977-02-22 DE DE19772707565 patent/DE2707565A1/de active Granted
- 1977-02-23 CA CA000272430A patent/CA1337522C/en not_active Expired - Lifetime
- 1977-02-25 CH CH244777A patent/CH638532A5/de not_active IP Right Cessation
- 1977-02-28 HU HU77FU348A patent/HU177441B/hu unknown
- 1977-03-01 IE IE440/77A patent/IE45597B1/en not_active IP Right Cessation
- 1977-03-02 AT AT138477A patent/AT358728B/de not_active IP Right Cessation
- 1977-03-10 FR FR7707173A patent/FR2348219A1/fr active Granted
- 1977-03-25 ES ES457191A patent/ES457191A1/es not_active Expired
- 1977-04-11 MX MX775624U patent/MX4985E/es unknown
- 1977-04-12 NL NL7703969A patent/NL191259C/xx not_active IP Right Cessation
- 1977-04-20 AR AR257178A patent/AR227864A1/es active
1978
- 1978-03-27 AR AR271541A patent/AR223143A1/es active
- 1978-04-12 ES ES468719A patent/ES468719A1/es not_active Expired
1979
- 1979-02-15 ES ES477741A patent/ES477741A1/es not_active Expired
- 1979-10-16 ES ES485064A patent/ES485064A1/es not_active Expired
- 1979-10-16 ES ES485061A patent/ES485061A1/es not_active Expired
- 1979-10-16 ES ES485062A patent/ES485062A1/es not_active Expired
- 1979-10-16 ES ES485063A patent/ES485063A1/es not_active Expired
1983
- 1983-07-26 CH CH409583A patent/CH643557A5/de not_active IP Right Cessation
- 1983-08-17 SE SE8304465A patent/SE457351B/sv not_active IP Right Cessation

Also Published As

Publication number	Publication date
SE457351B (sv)	1988-12-19
AT358728B (de)	1980-09-25
SE8304465D0 (sv)	1983-08-17
SE7701964L (sv)	1977-10-13
FR2348219B1 (da)	1982-12-03
HU177441B (en)	1981-10-28
CH643557A5 (en)	1984-06-15
CH638532A5 (de)	1983-09-30
DE2707565C2 (da)	1988-06-30
ES485063A1 (es)	1980-06-16
ES457191A1 (es)	1978-08-16
IE45597L (en)	1977-10-12
NL7703969A (nl)	1977-10-14
NL191259C (nl)	1995-04-18
NL191259B (nl)	1994-11-16
AR223143A1 (es)	1981-07-31
SE443981B (sv)	1986-03-17
AR227864A1 (es)	1982-12-30
MX4985E (es)	1983-01-31
ES468719A1 (es)	1979-10-16
ES477741A1 (es)	1980-04-01
FR2348219A1 (fr)	1977-11-10
ES485062A1 (es)	1980-06-16
DK75077A (da)	1977-10-13
DK162391B (da)	1991-10-21
CA1337522C (en)	1995-11-07
ES485061A1 (es)	1980-06-16
IE45597B1 (en)	1982-10-06
ATA138477A (de)	1980-02-15
DE2707565A1 (de)	1978-02-23
ES485064A1 (es)	1980-10-01

Publication	Publication Date	Title
DK162391C (da)	1992-03-09	Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DK129477A (da)	1977-09-26	Fremgangsmade til fremstilling af alkyloximderivater af 7-aminothiazolylacetamidocephalosporansyre
DK492677A (da)	1978-05-06	Fremgangsmaade til fremstilling af substituerede benzam9der
DK313477A (da)	1978-01-23	Fremgangsmade til fremstilling af nitrogenholdige heterocycliske forbindelser
DK161082C (da)	1991-11-04	Analogifremgangsmaade til fremstilling af syn-isomere oximderivater af 7-aminothiazolylacetamidocephalosporansyre
DK258078A (da)	1979-01-23	Fremgangsmaade til fremstilling af 7alfa-methoxy-7beta-(1,3-dithiethan-2-carboxamido) cephalosporansyre-derivater
DK286777A (da)	1977-12-30	Fremgangsmade til fremstilling af penicillansyrederivater
DK154079C (da)	1989-02-27	Fremgangsmaade til fremstilling af 4-halogen-2h-pyran-3(6h)-on-forbindelser
DK584777A (da)	1978-07-01	Fremgangsmaade til fremstilling af sterolinforbindelser
DK185577A (da)	1977-10-29	Fremgangsmade til fremstilling af heterocycliske forbindelser
DK12477A (da)	1977-07-15	Fremgangsmade til fremstilling af 7-aminothiazolylacetamidocephalosporansyrederivater
DK150484C (da)	1987-10-05	Analogifremgangsmaade til fremstilling af 4-amino-3-thiophencarboxylsyrederivater
DK369677A (da)	1978-02-21	Fremgangsmaade til fremstilling af oximderivater af 3-carbamoyloxymethyl-7-aminothiazolylacetamidocephalosponsyre
DK47677A (da)	1977-08-06	Fremgangsmade til fremstilling af 3-carbamoyloxymethyl-7-(amino-4-thiazolylacetamido)-cephalosporansyrederivater
DK86277A (da)	1977-08-28	Fremgangsmade til fremstilling af clavulamsyrederivater
DK138227B (da)	1978-07-31	Analogifremgangsmåde til fremstilling af substituerede xanthon-2-carboxylsyreforbindelser.
DK153554C (da)	1988-12-05	Fremgangsmaade til fremstilling af 7-aminocephalosporansyrederivater
DK209275A (da)	1975-11-29	Fremgangsmade til fremstilling af 2,3-polymethylen-5-sulfamoylbenzoesyreforbindelser
DK296676A (da)	1977-01-23	Fremgangsmade til fremstilling af 7-(alfa-amino-omega-(2,3-methylen-dioxyphenyl)acylamido)cephalosporansyrederivater
DK208677A (da)	1977-11-14	Fremgangsmade til fremstilling af maphthylforbindelser
DK296576A (da)	1977-01-23	Fremgangsmade til fremstilling af 7-(alfa-amino-omega-(3,4-methylen-dioxyphenyl)acylamido)cephalosporansyrederivater
DK284777A (da)	1977-12-29	Fremgangsmade til fremstilling af 7alfamethoxy-cephalosporansyre-derivater
DK88876A (da)	1977-09-02	Fremgangsmade til fremstilling af substituerede purinforbindelser
DK139691A (da)	1991-07-25	Fremgangsmaade til fremstilling af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
DK312976A (da)	1977-01-23	Fremgangsmade til fremstilling af 6-(alfa-amino-omega-(3,4-methylen-dioxyphenyl)acylamido)penicillansyrederivater