DK1663291T3 - Rekombinante lubricinmolekyler og anvendelser deraf - Google Patents

Rekombinante lubricinmolekyler og anvendelser deraf

Info

Publication number: DK1663291T3
Authority: DK; Denmark
Prior art keywords: recombinant lubricin; lubricin molecules; molecules; recombinant; lubricin
Prior art date: 2003-08-14

Application number

DK04781229.2T

Other languages

English (en)

Inventor

Carl Ralph Flannery

Christopher John Corcoran

Bethany Annis Freeman

Lisa Anne Racie

Original Assignee

Wyeth Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-08-14

Filing date

2004-08-13

Publication date

2012-07-02

2004-08-13 Application filed by Wyeth Llc filed Critical Wyeth Llc

2012-07-02 Application granted granted Critical

2012-07-02 Publication of DK1663291T3 publication Critical patent/DK1663291T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Toxicology (AREA)
Physical Education & Sports Medicine (AREA)
Marine Sciences & Fisheries (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Pulmonology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DK04781229.2T 2003-08-14 2004-08-13 Rekombinante lubricinmolekyler og anvendelser deraf DK1663291T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US49574103P	2003-08-14	2003-08-14
PCT/US2004/026508 WO2005016130A2 (en)	2003-08-14	2004-08-13	Recombinant lubricin molecules and uses thereof

Publications (1)

Publication Number	Publication Date
DK1663291T3 true DK1663291T3 (da)	2012-07-02

Family

ID=34193342

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04781229.2T DK1663291T3 (da)	2003-08-14	2004-08-13	Rekombinante lubricinmolekyler og anvendelser deraf

Country Status (21)

Country	Link
US (6)	US7642236B2 (da)
EP (1)	EP1663291B1 (da)
JP (1)	JP2007502122A (da)
KR (1)	KR101078202B1 (da)
CN (2)	CN102924584A (da)
AU (2)	AU2004264970B2 (da)
BR (1)	BRPI0413553A (da)
CR (1)	CR8204A (da)
DK (1)	DK1663291T3 (da)
EC (1)	ECSP066364A (da)
ES (1)	ES2388970T3 (da)
HK (1)	HK1089110A1 (da)
IL (2)	IL173258A (da)
MX (1)	MXPA06001658A (da)
NO (1)	NO20060475L (da)
NZ (1)	NZ545021A (da)
RU (2)	RU2376313C2 (da)
SG (1)	SG145724A1 (da)
UA (1)	UA91818C2 (da)
WO (1)	WO2005016130A2 (da)
ZA (1)	ZA200601291B (da)

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US6743774B1 (en)	1999-04-23	2004-06-01	Rhode Island Hospital	Tribonectins
US20080287369A1 (en) *	2004-07-23	2008-11-20	Jay Gregory D	Compositions and Methods for Viscosupplementation
US20090068247A1 (en) *	2007-09-12	2009-03-12	Mucosal Therapeutics	Biocompatible devices coated with a tribonectin and methods for their production
US20090104148A1 (en) *	2007-09-18	2009-04-23	Jay Gregory D	Treatment and prevention of joint disease
US8506944B2 (en)	2008-05-07	2013-08-13	The Regents Of The University Of California	Replenishment and enrichment of ocular surface lubrication
DK2915529T3 (da) *	2008-05-07	2017-08-07	Univ California	Terapeutisk regenerering og berigelse af okulær overfladesmøring
US8980840B2 (en)	2009-01-13	2015-03-17	Schepens Eye Research Institute	Therapeutic modulation of vaginal epithelium boundary lubrication
US9730865B2 (en)	2009-05-22	2017-08-15	Lubris, Llc	Application and uses of PRG4 and therapeutic modulation thereof
WO2011091000A2 (en) *	2010-01-19	2011-07-28	Singularis, Inc.	Oral care compositions and methods
US8716204B2 (en)	2010-07-27	2014-05-06	Zimmer, Inc.	Synthetic synovial fluid compositions and methods for making the same
US20130116186A1 (en) *	2011-10-04	2013-05-09	Rhode Island Hospital, A Lifespan Partner	Lubricin injections to maintain cartilage health
EP2948553B1 (en) *	2013-01-25	2020-04-01	Baylor College Of Medicine	A helper-dependent adenoviral gene therapy delivery and expression system
US20150010606A1 (en) *	2013-07-08	2015-01-08	Arthrex, Inc.	Intra-articular injection and implant attachment of molecule consisting of lubricin and extracellular superoxide dismutase or hyaluronic acid and extracellular superoxide dismutase
EP3057451A4 (en) *	2013-10-16	2017-06-21	Ensisheim Partners LLC	Protein-specific formulations
WO2015060935A1 (en) *	2013-10-22	2015-04-30	Lubris, Llc	Control of rheological properties of mixed hyaluronate/lubricin solutions
EP4062924A1 (en)	2013-11-26	2022-09-28	Lubris LLC	Compositions and methods for inhibiting intercellular interactions
WO2016123123A1 (en) *	2015-01-26	2016-08-04	Lubris Llc	Use of prg4 as an anti-inflammatory agent
HUE051774T2 (hu)	2016-01-13	2021-03-29	Genzyme Corp	Oszteoprotektív géneket, például HAS2-t és lubricint expresszáló rekombináns AAV vektorok, amelyek alkalmazhatók emlõsben oszteoartritisz és azzal kapcsolatos ízületi állapotok kezelésében
EP3408397B1 (en)	2016-01-27	2020-07-15	Just-Evotec Biologics, Inc.	Hybrid promoter and uses thereof
MX2020013869A (es) *	2018-06-21	2021-03-02	Lubris Llc	Lubricina para uso en curacion de heridas referencia cruzada con solicitudes relacionadas.
WO2020150396A1 (en) *	2019-01-15	2020-07-23	Cornell University	Recombinant lubricins, and compositions and methods for using the same
AR121396A1 (es) *	2020-02-24	2022-06-01	Novartis Ag	Purificación de polipéptidos producidos recombinantemente
IT202000022636A1 (it)	2020-09-25	2022-03-25	Ente Ospedaliero Specializzato In Gastroenterologia Istituto Nazionale Di Ricovero E Cura A Caratter	“terapia di combinazione di sorafenib e/o regorafenib con la proteina ricombinante umana proteoglicano-4 per il trattamento dell'epatocarcinoma”

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US5709020A (en) *	1994-07-19	1998-01-20	University Of Kentucky Research Foundation	Method for reducing the generation of wear particulates from an implant
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US5510122A (en) *	1994-09-28	1996-04-23	The Research Foundation Of State University Of New York	Preparation and use of whole saliva
US6743774B1 (en) *	1999-04-23	2004-06-01	Rhode Island Hospital	Tribonectins
US7001881B1 (en) *	1999-04-23	2006-02-21	Rhode Island Hospital	Tribonectins
US6960562B2 (en) *	1999-04-23	2005-11-01	Rhode Island Hospital, A Lifespan Partner	Tribonectin polypeptides and uses thereof
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2004
- 2004-08-13 CN CN2012104146501A patent/CN102924584A/zh active Pending
- 2004-08-13 RU RU2006107925/13A patent/RU2376313C2/ru not_active IP Right Cessation
- 2004-08-13 SG SG200805896-8A patent/SG145724A1/en unknown
- 2004-08-13 JP JP2006523436A patent/JP2007502122A/ja active Pending
- 2004-08-13 KR KR1020067003110A patent/KR101078202B1/ko not_active IP Right Cessation
- 2004-08-13 US US10/567,764 patent/US7642236B2/en not_active Expired - Fee Related
- 2004-08-13 ES ES04781229T patent/ES2388970T3/es not_active Expired - Lifetime
- 2004-08-13 UA UAA200602706A patent/UA91818C2/ru unknown
- 2004-08-13 WO PCT/US2004/026508 patent/WO2005016130A2/en active Application Filing
- 2004-08-13 BR BRPI0413553-9A patent/BRPI0413553A/pt not_active IP Right Cessation
- 2004-08-13 MX MXPA06001658A patent/MXPA06001658A/es active IP Right Grant
- 2004-08-13 AU AU2004264970A patent/AU2004264970B2/en not_active Ceased
- 2004-08-13 EP EP04781229A patent/EP1663291B1/en not_active Expired - Lifetime
- 2004-08-13 CN CNA2004800299041A patent/CN1867350A/zh active Pending
- 2004-08-13 DK DK04781229.2T patent/DK1663291T3/da active
- 2004-08-13 NZ NZ545021A patent/NZ545021A/en not_active IP Right Cessation
2006
- 2006-01-19 IL IL173258A patent/IL173258A/en not_active IP Right Cessation
- 2006-01-19 CR CR8204A patent/CR8204A/es unknown
- 2006-01-30 NO NO20060475A patent/NO20060475L/no not_active Application Discontinuation
- 2006-02-13 ZA ZA200601291A patent/ZA200601291B/xx unknown
- 2006-02-14 EC EC2006006364A patent/ECSP066364A/es unknown
- 2006-10-10 HK HK06111118.8A patent/HK1089110A1/xx unknown
2009
- 2009-06-24 IL IL199528A patent/IL199528A/en not_active IP Right Cessation
- 2009-08-07 RU RU2009130434/10A patent/RU2009130434A/ru not_active Application Discontinuation
- 2009-11-19 US US12/622,141 patent/US7893029B2/en not_active Expired - Fee Related
- 2009-11-23 US US12/624,112 patent/US7897571B2/en not_active Expired - Fee Related
2010
- 2010-04-16 AU AU2010201537A patent/AU2010201537B2/en not_active Ceased
2011
- 2011-02-25 US US13/035,529 patent/US8420793B2/en not_active Expired - Fee Related
2013
- 2013-03-08 US US13/791,346 patent/US8987205B2/en not_active Expired - Fee Related
2015
- 2015-02-05 US US14/614,809 patent/US20150343019A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1663291A2 (en)	2006-06-07
US7642236B2 (en)	2010-01-05
CN102924584A (zh)	2013-02-13
IL173258A0 (en)	2006-06-11
NZ545021A (en)	2009-03-31
SG145724A1 (en)	2008-09-29
US8987205B2 (en)	2015-03-24
CN1867350A (zh)	2006-11-22
ZA200601291B (en)	2010-08-25
IL199528A (en)	2013-03-24
NO20060475L (no)	2006-03-13
IL173258A (en)	2010-12-30
US8420793B2 (en)	2013-04-16
RU2006107925A (ru)	2006-07-27
MXPA06001658A (es)	2006-04-28
US7893029B2 (en)	2011-02-22
AU2004264970B2 (en)	2010-02-11
ECSP066364A (es)	2006-08-30
UA91818C2 (ru)	2010-09-10
US20110189731A1 (en)	2011-08-04
IL199528A0 (en)	2011-08-01
BRPI0413553A (pt)	2006-10-17
RU2009130434A (ru)	2011-02-20
AU2010201537B2 (en)	2012-02-23
RU2376313C2 (ru)	2009-12-20
AU2010201537A1 (en)	2010-05-06
KR101078202B1 (ko)	2011-11-01
US20130196930A1 (en)	2013-08-01
HK1089110A1 (en)	2006-11-24
ES2388970T3 (es)	2012-10-22
US20150343019A1 (en)	2015-12-03
US7897571B2 (en)	2011-03-01
EP1663291B1 (en)	2012-06-06
WO2005016130A2 (en)	2005-02-24
US20070191268A1 (en)	2007-08-16
WO2005016130A3 (en)	2006-02-02
CR8204A (es)	2007-10-01
KR20060072124A (ko)	2006-06-27
US20100080848A1 (en)	2010-04-01
US20100074935A1 (en)	2010-03-25
EP1663291A4 (en)	2009-08-05
JP2007502122A (ja)	2007-02-08
AU2004264970A1 (en)	2005-02-24

Publication	Publication Date	Title
DK1663291T3 (da)	2012-07-02	Rekombinante lubricinmolekyler og anvendelser deraf
CY2018009I2 (el)	2018-06-27	Παραλλαγες ανοσοσφαιρινων και χρησεις αυτων
DK1641822T3 (da)	2013-07-22	Heterologe il-17-a/f-polypeptider og terapeutiske anvendelser deraf.
DK1680443T3 (da)	2013-12-16	Stabiliserede alfa-helix-peptider og anvendelser heraf
DK1711207T3 (da)	2013-03-11	Interferon-alpha-antistoffer og anvendelse heraf
DK1404809T3 (da)	2014-03-17	Forbedrede hudsubstitutter og anvendelser deraf
DK1513873T3 (da)	2014-11-03	Terapeutiske epitoper og anvendelser deraf
DK1673460T3 (da)	2013-02-04	Rekombinante vacciner og anvendelse af disse
ATE486091T1 (de)	2010-11-15	Vegf-fallen und therapeutische verwendungen dafür
NO20055568D0 (no)	2005-11-24	Substituerte 1,4-diazepiner og anvendelser derav
DE60326145D1 (de)	2009-03-26	Spielermittlungsverfahren
ATE423117T1 (de)	2009-03-15	Heterocyclische 7-aminoalkylidenylchinolone und - naphthyridone
DE602005003819D1 (de)	2008-01-24	Perfluoroelastomer- und fluoroplastikgemische
DK1601744T3 (da)	2012-08-20	Forgasningsapparat og fremgangsmåde
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