DK1523486T3 - Tetracykliske arylsulfonylindoler med serotoninreceptor-affinitet - Google Patents
Tetracykliske arylsulfonylindoler med serotoninreceptor-affinitetInfo
- Publication number
- DK1523486T3 DK1523486T3 DK03760857T DK03760857T DK1523486T3 DK 1523486 T3 DK1523486 T3 DK 1523486T3 DK 03760857 T DK03760857 T DK 03760857T DK 03760857 T DK03760857 T DK 03760857T DK 1523486 T3 DK1523486 T3 DK 1523486T3
- Authority
- DK
- Denmark
- Prior art keywords
- pharmaceutically acceptable
- compound
- serotonin receptor
- receptor affinity
- indoles
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN478CH2002 | 2002-06-21 | ||
| PCT/IN2003/000222 WO2004000849A2 (en) | 2002-06-21 | 2003-06-19 | Tetracyclic arylsulfonyl indoles having serotonin receptor affinity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1523486T3 true DK1523486T3 (da) | 2008-03-03 |
Family
ID=29798513
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03760857T DK1523486T3 (da) | 2002-06-21 | 2003-06-19 | Tetracykliske arylsulfonylindoler med serotoninreceptor-affinitet |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7649097B2 (de) |
| EP (1) | EP1523486B1 (de) |
| JP (1) | JP4473120B2 (de) |
| CN (1) | CN100378108C (de) |
| AT (1) | ATE377603T1 (de) |
| AU (1) | AU2003249582B2 (de) |
| BR (1) | BR0312176A (de) |
| CA (1) | CA2490254C (de) |
| DE (1) | DE60317333T2 (de) |
| DK (1) | DK1523486T3 (de) |
| ES (1) | ES2297216T3 (de) |
| HK (1) | HK1074843A1 (de) |
| MX (1) | MXPA04012832A (de) |
| NZ (1) | NZ537770A (de) |
| RU (1) | RU2340619C2 (de) |
| WO (1) | WO2004000849A2 (de) |
| ZA (1) | ZA200409886B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1567492B1 (de) * | 2002-11-28 | 2013-05-22 | Suven Life Sciences Limited | N-arylsulfonyl-3-aminoalkoxyindole |
| JP4571507B2 (ja) * | 2002-12-18 | 2010-10-27 | スベン ライフ サイエンシズ リミティド | セロトニン受容体親和性を有する四環系３−置換インドール |
| PT1704154E (pt) * | 2004-01-02 | 2009-08-05 | Suven Life Sciences Ltd | Novos indeno[2,1a]indenos e isoindol[2,1-a]indóis |
| MXPA06011420A (es) * | 2004-04-01 | 2007-04-20 | Cardiome Pharma Corp | Compuestos pegilados de modulacion de canal de iones. |
| PT1856132E (pt) * | 2005-03-08 | 2009-06-09 | Suven Life Sciences Ltd | Processo para preparar benzotiazinoindoles substituídos |
| KR20220131520A (ko) | 2019-12-26 | 2022-09-28 | 길가메쉬 파마슈티컬스, 인코포레이티드 | 아릴시클로헥실아민 유도체 및 정신장애 치료에서의 이의 용도 |
| CN115135320B (zh) | 2020-02-18 | 2023-08-29 | 吉尔伽美什制药公司 | 用于治疗情绪障碍的特定色胺 |
| KR20230012501A (ko) | 2020-05-19 | 2023-01-26 | 사이빈 아이알엘 리미티드 | 중수소화된 트립타민 유도체 및 사용 방법 |
| WO2021250434A1 (en) | 2020-06-12 | 2021-12-16 | Beckley Psytech Limited | Composition comprising a benzoate salt of 5-methoxy-n,n-dimethyltryptamine |
| GB202212116D0 (en) | 2022-08-19 | 2022-10-05 | Beckley Psytech Ltd | Pharmaceutically acceptable salts and Compositions thereof |
| US12129234B1 (en) | 2023-08-03 | 2024-10-29 | Gilgamesh Pharmaceuticals, Inc. | Crystalline salts of N-ethyl-(5-fluoro-1H-indol-3-yl)-N-methylethan-1-amine |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3481953A (en) * | 1967-12-18 | 1969-12-02 | American Home Prod | 1-arylsulfonyl-3-(2-substituted ethyl) indoles |
| ZA795239B (en) | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
| BE889931A (fr) | 1980-08-12 | 1982-02-11 | Glaxo Group Ltd | Derives indoliques, leur preparation et leurs applications en tant que medicaments |
| GB8600397D0 (en) | 1986-01-08 | 1986-02-12 | Glaxo Group Ltd | Chemical compounds |
| GB8719167D0 (en) | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
| GB8724912D0 (en) | 1987-10-23 | 1987-11-25 | Wellcome Found | Indole derivatives |
| GB8819024D0 (en) | 1988-08-10 | 1988-09-14 | Glaxo Group Ltd | Chemical compounds |
| IL96891A0 (en) | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
| CA2042295A1 (fr) | 1990-05-15 | 1991-11-16 | Jacques Chauveau | Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant |
| ATE156823T1 (de) | 1990-06-07 | 1997-08-15 | Zeneca Ltd | Therapeutische heterocyclische verbindungen |
| SK278998B6 (sk) | 1991-02-01 | 1998-05-06 | Merck Sharp & Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu, spôsob i |
| GB9113802D0 (en) | 1991-06-26 | 1991-08-14 | Smithkline Beecham Plc | Medicaments |
| GB9210400D0 (en) | 1992-05-15 | 1992-07-01 | Merck Sharp & Dohme | Therapeutic agents |
| KR940007001A (ko) | 1992-09-16 | 1994-04-26 | 최승주 | 새로운 n-신나모일-2-메틸-5-메톡시-3-인돌 아세트산 에스테르, 그 제조방법 및 이를 함유하는 약학적 제제 |
| JP2000026471A (ja) * | 1998-07-10 | 2000-01-25 | Nippon Soda Co Ltd | １１−ホルミル−インドロ［１，２−ｂ］［１，２］ベンズイソチアゾールおよび農園芸用殺菌剤 |
| GB9820113D0 (en) * | 1998-09-15 | 1998-11-11 | Merck Sharp & Dohme | Therapeutic agents |
| WO2000034242A1 (en) | 1998-12-11 | 2000-06-15 | Virginia Commonwealth University | Selective 5-ht6 receptor ligands |
| EP1379239B1 (de) | 2001-03-29 | 2007-09-12 | Eli Lilly And Company | N-(2-arylethyl) benzylamine als 5-ht6 rezeptor-antagoniste |
-
2003
- 2003-06-19 DE DE60317333T patent/DE60317333T2/de not_active Expired - Lifetime
- 2003-06-19 MX MXPA04012832A patent/MXPA04012832A/es active IP Right Grant
- 2003-06-19 ES ES03760857T patent/ES2297216T3/es not_active Expired - Lifetime
- 2003-06-19 AU AU2003249582A patent/AU2003249582B2/en not_active Ceased
- 2003-06-19 RU RU2005101344/04A patent/RU2340619C2/ru not_active IP Right Cessation
- 2003-06-19 US US10/519,219 patent/US7649097B2/en not_active Expired - Fee Related
- 2003-06-19 CN CNB038146029A patent/CN100378108C/zh not_active Expired - Fee Related
- 2003-06-19 EP EP03760857A patent/EP1523486B1/de not_active Expired - Lifetime
- 2003-06-19 NZ NZ537770A patent/NZ537770A/en not_active IP Right Cessation
- 2003-06-19 AT AT03760857T patent/ATE377603T1/de active
- 2003-06-19 BR BR0312176-3A patent/BR0312176A/pt not_active IP Right Cessation
- 2003-06-19 WO PCT/IN2003/000222 patent/WO2004000849A2/en active IP Right Grant
- 2003-06-19 CA CA2490254A patent/CA2490254C/en not_active Expired - Fee Related
- 2003-06-19 DK DK03760857T patent/DK1523486T3/da active
- 2003-06-19 JP JP2004515418A patent/JP4473120B2/ja not_active Expired - Fee Related
-
2004
- 2004-12-07 ZA ZA200409886A patent/ZA200409886B/en unknown
-
2005
- 2005-10-06 HK HK05108865A patent/HK1074843A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2490254A1 (en) | 2003-12-31 |
| US7649097B2 (en) | 2010-01-19 |
| ATE377603T1 (de) | 2007-11-15 |
| CN1662544A (zh) | 2005-08-31 |
| US20050203154A1 (en) | 2005-09-15 |
| ES2297216T3 (es) | 2008-05-01 |
| WO2004000849A2 (en) | 2003-12-31 |
| NZ537770A (en) | 2007-03-30 |
| CN100378108C (zh) | 2008-04-02 |
| DE60317333T2 (de) | 2008-08-28 |
| RU2340619C2 (ru) | 2008-12-10 |
| JP2005535621A (ja) | 2005-11-24 |
| RU2005101344A (ru) | 2005-08-20 |
| ZA200409886B (en) | 2006-07-26 |
| AU2003249582B2 (en) | 2006-08-03 |
| AU2003249582A1 (en) | 2004-01-06 |
| HK1074843A1 (en) | 2005-11-25 |
| MXPA04012832A (es) | 2005-05-27 |
| BR0312176A (pt) | 2005-04-05 |
| EP1523486A2 (de) | 2005-04-20 |
| EP1523486B1 (de) | 2007-11-07 |
| DE60317333D1 (de) | 2007-12-20 |
| JP4473120B2 (ja) | 2010-06-02 |
| WO2004000849A3 (en) | 2004-03-25 |
| CA2490254C (en) | 2011-11-01 |
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