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DK1567140T3 - Synergistisk kombination der omfatter roflumilast og (R,R)-formoterol - Google Patents

Synergistisk kombination der omfatter roflumilast og (R,R)-formoterol

Info

Publication number
DK1567140T3
DK1567140T3 DK03780056T DK03780056T DK1567140T3 DK 1567140 T3 DK1567140 T3 DK 1567140T3 DK 03780056 T DK03780056 T DK 03780056T DK 03780056 T DK03780056 T DK 03780056T DK 1567140 T3 DK1567140 T3 DK 1567140T3
Authority
DK
Denmark
Prior art keywords
roflumilast
formoterol
synergistic combination
treatment
relates
Prior art date
Application number
DK03780056T
Other languages
Danish (da)
English (en)
Inventor
Rolf Beume
Degenhard Marx
Stefan-Lutz Wollin
Daniela Bundschuh
Christian Weimar
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of DK1567140T3 publication Critical patent/DK1567140T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK03780056T 2002-11-27 2003-11-26 Synergistisk kombination der omfatter roflumilast og (R,R)-formoterol DK1567140T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02026504 2002-11-27
PCT/EP2003/013266 WO2004047828A1 (en) 2002-11-27 2003-11-26 Synergistic combination compresing roflumilas and (r.r) -formoterol

Publications (1)

Publication Number Publication Date
DK1567140T3 true DK1567140T3 (da) 2008-11-03

Family

ID=32338001

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03780056T DK1567140T3 (da) 2002-11-27 2003-11-26 Synergistisk kombination der omfatter roflumilast og (R,R)-formoterol

Country Status (32)

Country Link
US (1) US20060199865A1 (ko)
EP (1) EP1567140B1 (ko)
JP (1) JP2006508993A (ko)
KR (1) KR20050094810A (ko)
CN (1) CN1713902A (ko)
AT (1) ATE399544T1 (ko)
AU (1) AU2003288169B8 (ko)
BR (1) BR0316475A (ko)
CA (1) CA2506956C (ko)
CO (1) CO5690571A2 (ko)
CY (1) CY1110368T1 (ko)
DE (1) DE60321954D1 (ko)
DK (1) DK1567140T3 (ko)
EA (1) EA009990B1 (ko)
ES (1) ES2309374T3 (ko)
HK (1) HK1081862A1 (ko)
HR (1) HRP20050580B1 (ko)
IL (1) IL168307A (ko)
IS (1) IS2576B (ko)
MA (1) MA27538A1 (ko)
ME (1) ME00488B (ko)
MX (1) MXPA05005438A (ko)
NO (1) NO334148B1 (ko)
NZ (1) NZ540658A (ko)
PL (1) PL214869B1 (ko)
PT (1) PT1567140E (ko)
RS (1) RS51082B (ko)
SI (1) SI1567140T1 (ko)
TN (1) TNSN05130A1 (ko)
UA (1) UA83017C2 (ko)
WO (1) WO2004047828A1 (ko)
ZA (1) ZA200503307B (ko)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
US7470791B2 (en) 2003-03-10 2008-12-30 Nycomed Gmbh Process for the preparation of roflumilast
CA2601250C (en) 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
WO2013077830A1 (en) * 2011-11-25 2013-05-30 Mahmut Bilgic Synergistilly active combinations of roflumilast and carmoterol
CN103784443A (zh) * 2014-02-18 2014-05-14 青岛市城阳区人民医院 一种包含沙美特罗和罗氟司特的药物组合产品

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5795564A (en) * 1991-04-05 1998-08-18 Sepracor, Inc. Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
JP2001503772A (ja) * 1996-11-11 2001-03-21 セプラクール，インコーポレイテッド フォルモテロールの光学的に純粋な異性体の製造方法
TR199901772T2 (ko) * 1997-02-17 1999-09-21 Byk Gulden Lomberg Chemische Fabrik Gmbh
US6333354B1 (en) * 1997-02-28 2001-12-25 Byk Gulden Lomberg Chemische Fabrik Gmbh Synergistic combination of PDE inhibitors and adenylate cyclase agonists or guanyl cyclyse agonists
US6624181B1 (en) * 1997-02-28 2003-09-23 Altana Pharma Ag Synergistic combination
CN1314811A (zh) * 1998-08-26 2001-09-26 史密丝克莱恩比彻姆公司 治疗肺病的方法
US6303145B2 (en) * 1999-05-10 2001-10-16 Sepracor Inc. (S,R) formoterol methods and compositions
CN1202865C (zh) * 1999-08-21 2005-05-25 奥坦纳医药公司 增效组合物
GB0103630D0 (en) * 2001-02-14 2001-03-28 Glaxo Group Ltd Chemical compounds
ATE381537T1 (de) * 2001-03-22 2008-01-15 Glaxo Group Ltd Formanilid-derivative als beta2-adrenorezeptor- agonisten
CA2445839A1 (en) * 2001-04-30 2002-11-07 Glaxo Group Limited Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha

Also Published As

Publication number Publication date
AU2003288169B8 (en) 2010-08-26
MA27538A1 (fr) 2005-09-01
IS2576B (is) 2010-02-15
EA200500865A1 (ru) 2005-12-29
CN1713902A (zh) 2005-12-28
KR20050094810A (ko) 2005-09-28
NO20053023L (no) 2005-06-20
RS51082B (sr) 2010-10-31
TNSN05130A1 (en) 2007-05-14
EP1567140A1 (en) 2005-08-31
DE60321954D1 (de) 2008-08-14
HK1081862A1 (en) 2006-05-26
AU2003288169A1 (en) 2004-06-18
WO2004047828A1 (en) 2004-06-10
JP2006508993A (ja) 2006-03-16
PT1567140E (pt) 2008-09-24
MXPA05005438A (es) 2005-08-03
ES2309374T3 (es) 2008-12-16
EP1567140B1 (en) 2008-07-02
BR0316475A (pt) 2005-10-11
ZA200503307B (en) 2006-11-29
CA2506956C (en) 2012-10-02
IL168307A (en) 2010-12-30
EA009990B1 (ru) 2008-04-28
NZ540658A (en) 2007-03-30
HRP20050580B1 (hr) 2014-04-11
SI1567140T1 (sl) 2008-12-31
RS20050383A (en) 2007-08-03
US20060199865A1 (en) 2006-09-07
NO334148B1 (no) 2013-12-16
UA83017C2 (uk) 2008-06-10
CA2506956A1 (en) 2004-06-10
ME00488B (me) 2011-10-10
PL375632A1 (en) 2005-12-12
CY1110368T1 (el) 2015-04-29
ATE399544T1 (de) 2008-07-15
IS7899A (is) 2005-06-20
HRP20050580A2 (en) 2006-08-31
CO5690571A2 (es) 2006-10-31
PL214869B1 (pl) 2013-09-30
AU2003288169B2 (en) 2010-01-07

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