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DK1557473T3 - Reagent composition to distinguish beta-lactamases, kits and methods thereof - Google Patents

Reagent composition to distinguish beta-lactamases, kits and methods thereof

Info

Publication number
DK1557473T3
DK1557473T3 DK03769947T DK03769947T DK1557473T3 DK 1557473 T3 DK1557473 T3 DK 1557473T3 DK 03769947 T DK03769947 T DK 03769947T DK 03769947 T DK03769947 T DK 03769947T DK 1557473 T3 DK1557473 T3 DK 1557473T3
Authority
DK
Denmark
Prior art keywords
beta
lactamase
reagent composition
lactamases
composition
Prior art date
Application number
DK03769947T
Other languages
Danish (da)
Inventor
Atsushi Murata
Original Assignee
Hanaki Hideaki
Showa Pharm Chem Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanaki Hideaki, Showa Pharm Chem Ind filed Critical Hanaki Hideaki
Application granted granted Critical
Publication of DK1557473T3 publication Critical patent/DK1557473T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/978—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • G01N2333/986—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in cyclic amides (3.5.2), e.g. beta-lactamase (penicillinase, 3.5.2.6), creatinine amidohydrolase (creatininase, EC 3.5.2.10), N-methylhydantoinase (3.5.2.6)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The present invention provides a reagent composition for detecting beta -lactamase including as a beta -lactamase detection substrate 3-Ä2,4-dinitrostyrylÜ-7-(2-thienylacetamidoÜ-3-cephem-4-carboxylic acid, or 7-Ä2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxy-imino)acetamidoÜ-3-(2,4-dinitrostyryl)-3-cephem-4-carboxylic acid, and at least one beta -lactamase inhibitor selected from the group consisting of clavulanic acid, aztreonam, ethylenediaminetetraacetic acid, and cloxacillin, which composition can detect beta -lactamases rapidly and easily with high sensitivity. The present invention also provides a detection kit including the detecting reagent composition. Further, the present invention provides a beta -lactamase detection method where a liquid specimen containing a target substance to be analyzed is brought into contact with the composition. <IMAGE>
DK03769947T 2002-10-29 2003-10-29 Reagent composition to distinguish beta-lactamases, kits and methods thereof DK1557473T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002314681 2002-10-29
PCT/JP2003/013835 WO2004040008A1 (en) 2002-10-29 2003-10-29 REAGENT COMPOSITION FOR DETECTING β-LACTAMASE, DETECTION KIT AND DETECTION METHOD

Publications (1)

Publication Number Publication Date
DK1557473T3 true DK1557473T3 (en) 2009-05-04

Family

ID=32211621

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03769947T DK1557473T3 (en) 2002-10-29 2003-10-29 Reagent composition to distinguish beta-lactamases, kits and methods thereof

Country Status (11)

Country Link
US (1) US20060014230A1 (en)
EP (1) EP1557473B1 (en)
KR (1) KR20050083843A (en)
CN (1) CN1729299A (en)
AT (1) ATE425261T1 (en)
AU (1) AU2003280590A1 (en)
CA (1) CA2504183A1 (en)
DE (1) DE60326622D1 (en)
DK (1) DK1557473T3 (en)
ES (1) ES2324031T3 (en)
WO (1) WO2004040008A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002251755C1 (en) * 2001-01-12 2008-07-10 The Regents Of The University Of California Beta-lactamase substrates having phenolic ethers
WO2005071096A2 (en) 2004-01-21 2005-08-04 Molecular Probes, Inc. Derivatives of cephalosporin and clavulanic acid for detecting beta-lacamase in a sample
FR2881755B1 (en) * 2005-02-10 2012-11-30 Biomerieux Sa MEDIA FOR THE SPECIFIC DETECTION OF RESISTANT MICROORGANISMS
ES2645455T3 (en) 2006-12-19 2017-12-05 Becton, Dickinson And Company Chromogenic medium for detection and identification of vancomycin resistant enterococci and associated procedure
WO2009051838A1 (en) * 2007-10-19 2009-04-23 Becton Dickinson And Company Methods and compositions for the detection of beta-lactamases
WO2010047778A1 (en) 2008-10-20 2010-04-29 Becton Dickinson And Company Compositions for the detection of intracellular bacterial targets and other intracellular microorganism targets
CN101993910B (en) * 2009-08-11 2013-01-02 湘北威尔曼制药股份有限公司 Detection method and detection test paper for beta-lactamase
CN102115780B (en) * 2010-12-15 2013-01-30 黑龙江省乳品工业技术开发中心 Kit for detecting beta-lactamase as well as preparation and detection method thereof
CN103509083B (en) * 2012-06-28 2016-06-08 王郁生 A kind of wide spectrum beta-lactamase fluorogenic substrate and its preparation method and application
GB201317619D0 (en) 2013-10-04 2013-11-20 Uni I Oslo Compounds
KR20160011296A (en) 2014-07-21 2016-02-01 웹스씨스템(주) Specimen-Reagent Response Examination Kit and Bio Scanner Including the Same
FR3034523B1 (en) * 2015-04-03 2020-01-17 Universite De Bourgogne NOVEL METHOD FOR DETECTING THE PRESENCE OF BACTERIA PRODUCING BETA-LACTAMASES.
GB201613946D0 (en) 2016-08-15 2016-09-28 Univ Oslo Compounds
GB201712671D0 (en) * 2017-08-07 2017-09-20 Mast Group Ltd Chromogenic Carbapenemase detection method
CN107607719B (en) * 2017-11-02 2019-08-02 北京中生金域诊断技术股份有限公司 Beta-lactam enzyme method in a kind of measurement sample
CN107779494B (en) * 2017-11-02 2021-08-17 北京中生金域诊断技术股份有限公司 Kit for detecting infectious vaginitis and preparation method thereof
CN108330158A (en) * 2018-04-09 2018-07-27 江苏省产品质量监督检验研究院 Exogenous analysis method in a kind of fresh milk beta-lactamase
CN112666155A (en) * 2019-10-16 2021-04-16 广东第二师范学院 Kit for quantitatively detecting residues of various beta-lactamase inhibitors and use method thereof
CN111198266A (en) * 2020-01-09 2020-05-26 深圳市博奥通科生物制品有限公司 Rapid detection kit for sulbactam

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE789817A (en) 1971-10-07 1973-04-06 Glaxo Lab Ltd IMPROVEMENTS WITH CEPHALOSPORIN COMPOUNDS
JPH0635464B2 (en) * 1988-09-02 1994-05-11 明治製菓株式会社 Novel cephem compound, its production method and antibacterial agent
EP0538447B1 (en) * 1991-05-06 1997-05-28 Dade MicroScan Inc. Rapid inducible beta-lactamase screen test
US5641623A (en) * 1995-01-04 1997-06-24 Martin; Mark T. Electrochemiluminescence assay
US5741657A (en) * 1995-03-20 1998-04-21 The Regents Of The University Of California Fluorogenic substrates for β-lactamase and methods of use
JP3754993B2 (en) * 1999-02-04 2006-03-15 国立感染症研究所長 Method for distinguishing metallo-β-lactamase producing bacteria
CA2423328C (en) * 2000-09-22 2010-01-12 Zenyaku Kogyo Kabushiki Kaisha Cephem compound and esbl-detecting reagent containing the same
GB0106428D0 (en) * 2001-03-15 2001-05-02 Amura Ltd Antibacterial composition

Also Published As

Publication number Publication date
ATE425261T1 (en) 2009-03-15
EP1557473A4 (en) 2006-11-08
AU2003280590A1 (en) 2004-05-25
CN1729299A (en) 2006-02-01
EP1557473A1 (en) 2005-07-27
WO2004040008A1 (en) 2004-05-13
EP1557473B1 (en) 2009-03-11
DE60326622D1 (en) 2009-04-23
CA2504183A1 (en) 2004-05-13
ES2324031T3 (en) 2009-07-29
US20060014230A1 (en) 2006-01-19
KR20050083843A (en) 2005-08-26

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