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DK1556382T3 - 3-Phenylpyridoindolderivater, fremstilling og terapeutisk anvendelse deraf - Google Patents

3-Phenylpyridoindolderivater, fremstilling og terapeutisk anvendelse deraf

Info

Publication number
DK1556382T3
DK1556382T3 DK03810495T DK03810495T DK1556382T3 DK 1556382 T3 DK1556382 T3 DK 1556382T3 DK 03810495 T DK03810495 T DK 03810495T DK 03810495 T DK03810495 T DK 03810495T DK 1556382 T3 DK1556382 T3 DK 1556382T3
Authority
DK
Denmark
Prior art keywords
phenylpyridoindole
derivatives
preparation
therapeutic use
therapeutic
Prior art date
Application number
DK03810495T
Other languages
English (en)
Inventor
Camille-Georges Wermuth
Bernard Bourrie
Pierre Casellas
Paola Ciapetti
Jean-Marie Derocq
Samir Jegham
Yvette Muneaux
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of DK1556382T3 publication Critical patent/DK1556382T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK03810495T 2002-10-23 2003-10-21 3-Phenylpyridoindolderivater, fremstilling og terapeutisk anvendelse deraf DK1556382T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0213264A FR2846329B1 (fr) 2002-10-23 2002-10-23 Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique
PCT/FR2003/003110 WO2004041817A1 (fr) 2002-10-23 2003-10-21 Derives de pyridoindolone substitues en -3 par un phenyle, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
DK1556382T3 true DK1556382T3 (da) 2008-10-06

Family

ID=32088223

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03810495T DK1556382T3 (da) 2002-10-23 2003-10-21 3-Phenylpyridoindolderivater, fremstilling og terapeutisk anvendelse deraf

Country Status (33)

Country Link
US (2) US7390818B2 (da)
EP (1) EP1556382B1 (da)
JP (1) JP4488899B2 (da)
KR (1) KR101051859B1 (da)
CN (1) CN100345850C (da)
AR (1) AR041689A1 (da)
AT (1) ATE396994T1 (da)
AU (1) AU2003296769B2 (da)
BR (1) BR0314883A (da)
CA (1) CA2502769C (da)
CY (1) CY1109785T1 (da)
DE (1) DE60321372D1 (da)
DK (1) DK1556382T3 (da)
EA (1) EA010833B1 (da)
ES (1) ES2304546T3 (da)
FR (1) FR2846329B1 (da)
HK (1) HK1074446A1 (da)
HR (1) HRP20050362B1 (da)
IL (1) IL168133A (da)
IS (1) IS2641B (da)
MA (1) MA27455A1 (da)
ME (1) ME00102B (da)
MX (1) MXPA05004349A (da)
NO (1) NO331297B1 (da)
NZ (1) NZ539866A (da)
PL (1) PL214867B1 (da)
PT (1) PT1556382E (da)
RS (1) RS51605B (da)
SI (1) SI1556382T1 (da)
TW (1) TWI325864B (da)
UA (1) UA79317C2 (da)
WO (1) WO2004041817A1 (da)
ZA (1) ZA200503231B (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2823975B1 (fr) 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
US7456193B2 (en) 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
US20100297252A1 (en) 2003-03-03 2010-11-25 Elan Pharma International Ltd. Nanoparticulate meloxicam formulations
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
FR2869316B1 (fr) * 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2876377B1 (fr) * 2004-10-11 2007-03-16 Univ Claude Bernard Lyon Nouveaux derives de 9h-pyrido[2,3-b]indole, leur procede de preparation, ainsi que les compositions pharmaceutiques contenant de tels composes
FR2892416B1 (fr) * 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique
EP2435027B1 (en) 2009-05-27 2016-10-05 Alkermes Pharma Ireland Limited Reduction of flake-like aggregation in nanoparticulate meloxicam compositions
FR2959133A1 (fr) 2010-04-22 2011-10-28 Sanofi Aventis Formulation pharmaceutique anticancereuse
FR2945950A1 (fr) 2009-05-27 2010-12-03 Elan Pharma Int Ltd Compositions de nanoparticules anticancereuses et procedes pour les preparer
CN107459481A (zh) * 2017-07-25 2017-12-12 广州大学 一种3‑（4‑甲氧基苯基）‑6‑甲氧基‑4‑氯‑5,7‑二溴喹啉的合成方法
KR102660608B1 (ko) * 2019-02-01 2024-04-26 지앙수 아오사이캉 파마수티칼 씨오., 엘티디. c-Met억제제로서 피리미디닐기를 포함하는 삼환식 화합물
CN113329276B (zh) * 2020-02-28 2022-10-28 华为技术有限公司 数据传输方法、装置、网关、芯片及存储介质
CN116171156A (zh) * 2020-07-31 2023-05-26 南京明德新药研发有限公司 含嘧啶基团的三并环类化合物的盐型、晶型及其制备方法
US20240132446A1 (en) * 2021-05-26 2024-04-25 Refined Technologies, Inc. Compositions and methods for removal of n-methyl-2-pyrrolidone (nmp) degradation products and other foulants from nmp purification systems

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1268772A (en) 1968-03-15 1972-03-29 Glaxo Lab Ltd NOVEL alpha-CARBOLINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME
US4263304A (en) * 1978-06-05 1981-04-21 Sumitomo Chemical Company, Limited 7 H-indolo[2,3-c]isoquinolines
SU833971A1 (ru) 1979-07-10 1981-05-30 Ленинградский Химико-Фармацевтическийинститут Способ получени 3-фенил-2-оксо- - КАРбОлиНОВ
FR2595701B1 (fr) * 1986-03-17 1988-07-01 Sanofi Sa Derives du pyrido-indole, leur application a titre de medicaments et les compositions les renfermant
JPH10501686A (ja) 1994-04-13 1998-02-17 ザ ロックフェラー ユニヴァーシティ 神経系の細胞へのｄｎａのａａｖ仲介送達
DE19502753A1 (de) * 1995-01-23 1996-07-25 Schering Ag Neue 9H-Pyrido[3,4-b]indol-Derivate
FR2765581B1 (fr) * 1997-07-03 1999-08-06 Synthelabo Derives de 3-aryl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one, leur preparation et leur application en therapeutique
FR2765582B1 (fr) 1997-07-03 1999-08-06 Synthelabo Derives de 3-alkyl-1,9-dihydro-2h-pyrido[2,3-b]indol-2-one leur preparation et leur application en therapeutique
EP1068205A1 (en) 1998-04-02 2001-01-17 Neurogen Corporation Aminoalkyl substituted 5,6,7,8-tetrahydro-9h pyrimidino 2,3-b]indole and 5,6,7,8-tetrahydro-9h-pyrimidino 4,5-b]indole derivatives: crf1 specific ligands
IT1313592B1 (it) * 1999-08-03 2002-09-09 Novuspharma Spa Derivati di 1h-pirido 3,4-b indol-1-one.
US20020156016A1 (en) 2001-03-30 2002-10-24 Gerald Minuk Control of cell growth by altering cell membrane potentials
FR2823975B1 (fr) * 2001-04-27 2003-05-30 Sanofi Synthelabo Nouvelle utilisation de pyridoindolone
US7456193B2 (en) * 2002-10-23 2008-11-25 Sanofi-Aventis Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
FR2846330B1 (fr) 2002-10-23 2004-12-03 Sanofi Synthelabo Derives de pyridoindolone substitues en -3 par groupe heterocyclique, leur preparation et leur application en therapeutique
FR2869316B1 (fr) * 2004-04-21 2006-06-02 Sanofi Synthelabo Derives de pyridoindolone substitues en -6, leur preparation et leur application en therapeutique.
FR2892416B1 (fr) 2005-10-20 2008-06-27 Sanofi Aventis Sa Derives de 6-heteroarylpyridoindolone, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
EP1556382B1 (fr) 2008-05-28
JP4488899B2 (ja) 2010-06-23
US7390818B2 (en) 2008-06-24
FR2846329A1 (fr) 2004-04-30
JP2006511498A (ja) 2006-04-06
ATE396994T1 (de) 2008-06-15
HRP20050362B1 (hr) 2014-01-31
NO331297B1 (no) 2011-11-21
ZA200503231B (en) 2006-06-28
ME00102B (me) 2010-10-10
IL168133A (en) 2010-05-31
MA27455A1 (fr) 2005-07-01
US8012991B2 (en) 2011-09-06
EA010833B1 (ru) 2008-12-30
CN100345850C (zh) 2007-10-31
AU2003296769A1 (en) 2004-06-07
RS51605B (en) 2011-08-31
EA200500521A1 (ru) 2005-12-29
TW200413368A (en) 2004-08-01
HRP20050362A2 (en) 2005-12-31
NO20051983L (no) 2005-07-22
RS20050362A (en) 2007-11-15
US20050288318A1 (en) 2005-12-29
ES2304546T3 (es) 2008-10-16
EP1556382A1 (fr) 2005-07-27
CA2502769C (en) 2011-03-15
NZ539866A (en) 2008-01-31
DE60321372D1 (de) 2008-07-10
US20080214538A1 (en) 2008-09-04
SI1556382T1 (sl) 2008-10-31
CY1109785T1 (el) 2014-09-10
CN1729190A (zh) 2006-02-01
MXPA05004349A (es) 2005-08-26
FR2846329B1 (fr) 2004-12-03
PL214867B1 (pl) 2013-09-30
NO20051983D0 (no) 2005-04-22
KR101051859B1 (ko) 2011-07-25
IS2641B (is) 2010-08-15
UA79317C2 (en) 2007-06-11
IS7815A (is) 2005-04-20
WO2004041817A1 (fr) 2004-05-21
AR041689A1 (es) 2005-05-26
CA2502769A1 (en) 2004-05-21
TWI325864B (en) 2010-06-11
KR20050086421A (ko) 2005-08-30
PT1556382E (pt) 2008-07-09
MEP22208A (en) 2010-06-10
AU2003296769B2 (en) 2010-02-04
BR0314883A (pt) 2005-08-02
PL376790A1 (pl) 2006-01-09
HK1074446A1 (en) 2005-11-11

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