DK149590C - Analogifremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo(4,1,0)hepten-(2)-on-(5)-forbindelser - Google Patents

Analogifremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo(4,1,0)hepten-(2)-on-(5)-forbindelser

Info

Publication number: DK149590C
Authority: DK; Denmark
Prior art keywords: diaza; bicyclo; aryl; compounds; preparation
Prior art date: 1978-12-16

Application number

DK532679A

Other languages

English (en)

Other versions

DK532679A (da

DK149590B (da

Inventor

Marco Thyes

Josef Gries

Hans Dieter Lehmann

Johannes Kunze

Dieter Lenke

Original Assignee

Basf Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-12-16

Filing date

1979-12-14

Publication date

1987-02-09

1979-12-14 Application filed by Basf Ag filed Critical Basf Ag

1980-06-17 Publication of DK532679A publication Critical patent/DK532679A/da

1986-08-04 Publication of DK149590B publication Critical patent/DK149590B/da

1987-02-09 Application granted granted Critical

1987-02-09 Publication of DK149590C publication Critical patent/DK149590C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C62/30—Unsaturated compounds
- C07C62/38—Unsaturated compounds containing keto groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Diabetes (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK532679A 1978-12-16 1979-12-14 Analogifremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo(4,1,0)hepten-(2)-on-(5)-forbindelser DK149590C (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2854475		1978-12-16
DE19782854475 DE2854475A1 (de)	1978-12-16	1978-12-16	Neue 3,4-diaza-bicyclo eckige klammer auf 4.1.0 eckige klammer zu hepten-(2)- one-(5), verfahren zu ihrer herstellung und diese verbindungen enthaltende therapeutische mittel

Publications (3)

Publication Number	Publication Date
DK532679A DK532679A (da)	1980-06-17
DK149590B DK149590B (da)	1986-08-04
DK149590C true DK149590C (da)	1987-02-09

Family

ID=6057438

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK532679A DK149590C (da)	1978-12-16	1979-12-14	Analogifremgangsmaade til fremstilling af 2-aryl-3,4-diaza-bicyclo(4,1,0)hepten-(2)-on-(5)-forbindelser

Country Status (10)

Country	Link
US (1)	US4271163A (da)
EP (1)	EP0012366B1 (da)
JP (1)	JPS5583758A (da)
AT (1)	ATE6643T1 (da)
CA (1)	CA1145749A (da)
DE (2)	DE2854475A1 (da)
DK (1)	DK149590C (da)
HU (1)	HU182454B (da)
IE (1)	IE49234B1 (da)
ZA (1)	ZA796789B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3124699A1 (de) *	1981-06-24	1983-01-13	Basf Ag, 6700 Ludwigshafen	Neue 2-aryl-3,4-diaza-bicyclo(4.n.0.)alken-(2)-one-(5),verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3209159A1 (de) *	1982-03-13	1983-09-15	Basf Ag, 6700 Ludwigshafen	Neue 6-aryl-4,5-dihydro-3(2h)-pyridazinone, verfahren zu ihrer herstellung, diese verbindungen enthaltende therapeutische mittel und deren verwendung
DE3302021A1 (de) *	1983-01-22	1984-07-26	Basf Ag, 6700 Ludwigshafen	6-aryl-4,5-dihydro-3(2h)-pyridazinone, ihre herstellung und verwendung
JP3442815B2 (ja) *	1992-05-13	2003-09-02	第一製薬株式会社	ジアザビシクロアルケン誘導体
IL115995A0 (en) *	1994-11-15	1996-01-31	Bayer Ag	Substituted 4-biarylbutyric or 5-biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors
US5789434A (en) *	1994-11-15	1998-08-04	Bayer Corporation	Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
US5886022A (en) *	1995-06-05	1999-03-23	Bayer Corporation	Substituted cycloalkanecarboxylic acid derivatives as matrix metalloprotease inhibitors
WO2020157199A1 (en)	2019-02-01	2020-08-06	Bayer Aktiengesellschaft	Annulated dihydropyridazinone compounds as anti-cancer compounds

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL37788A0 (en)	1970-10-09	1971-12-29	American Cyanamid Co	New pyridazinone compounds,their preparation and pharmaceutical compositions containing them
US3689652A (en) *	1970-10-09	1972-09-05	William Vincent Curran	Method of lowering blood pressure in mammals
FR2110329A1 (en) *	1970-10-09	1972-06-02	American Cyanamid Co	6-phenyl-pyridazin-3-one derivs - hypotensives
US3822260A (en) *	1970-10-09	1974-07-02	American Cyanamid Co	6-(cyanophenyl)-4,5-dihydro-3(2h)-pyridazinones
US3975388A (en) *	1971-02-22	1976-08-17	Bdh Pharmaceuticals Limited	Pyridazinones
GB1383906A (en)	1971-02-22	1974-02-12	Bdh Pharmaceuticals Ltd	Pyridazinones
US4088762A (en) *	1971-02-22	1978-05-09	Bdh Pharmaceuticals Limited	6-(P-PIPERAZINO)-PHENYL-4,5-DIHYDRO-3(2H)pyridazinones
US3746712A (en) *	1971-06-08	1973-07-17	A Ross	6-(substituted-phenyl)-5-methyl-4,5-dihydro-3(2h)-pyridazinones
US3812256A (en) *	1971-06-08	1974-05-21	American Cyanamid Co	Novel method for lowering blood pressure in mammals
JPS5221616B2 (da) *	1974-01-09	1977-06-11
DE2727481A1 (de)	1977-06-18	1979-01-11	Basf Ag	Dihydropyridazone und dihydropyridazone enthaltende therapeutische mittel

1978
- 1978-12-16 DE DE19782854475 patent/DE2854475A1/de not_active Withdrawn
1979
- 1979-11-30 US US06/098,854 patent/US4271163A/en not_active Expired - Lifetime
- 1979-12-06 EP EP79104956A patent/EP0012366B1/de not_active Expired
- 1979-12-06 AT AT79104956T patent/ATE6643T1/de not_active IP Right Cessation
- 1979-12-06 DE DE7979104956T patent/DE2966809D1/de not_active Expired
- 1979-12-12 CA CA000341754A patent/CA1145749A/en not_active Expired
- 1979-12-13 IE IE2418/79A patent/IE49234B1/en unknown
- 1979-12-14 DK DK532679A patent/DK149590C/da active
- 1979-12-14 HU HU79BA3905A patent/HU182454B/hu unknown
- 1979-12-14 ZA ZA00796789A patent/ZA796789B/xx unknown
- 1979-12-17 JP JP16290679A patent/JPS5583758A/ja active Granted

Also Published As

Publication number	Publication date
DK532679A (da)	1980-06-17
DE2854475A1 (de)	1980-07-03
US4271163A (en)	1981-06-02
HU182454B (en)	1984-01-30
EP0012366A1 (de)	1980-06-25
JPS5583758A (en)	1980-06-24
DK149590B (da)	1986-08-04
DE2966809D1 (en)	1984-04-19
CA1145749A (en)	1983-05-03
ATE6643T1 (de)	1984-03-15
IE49234B1 (en)	1985-09-04
IE792418L (en)	1980-06-16
JPS6328911B2 (da)	1988-06-10
ZA796789B (en)	1980-12-31
EP0012366B1 (de)	1984-03-14

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