DK1327146T3 - Forbindelse med et forgrenet linkermolekyle - Google Patents
Forbindelse med et forgrenet linkermolekyleInfo
- Publication number
- DK1327146T3 DK1327146T3 DK01985752T DK01985752T DK1327146T3 DK 1327146 T3 DK1327146 T3 DK 1327146T3 DK 01985752 T DK01985752 T DK 01985752T DK 01985752 T DK01985752 T DK 01985752T DK 1327146 T3 DK1327146 T3 DK 1327146T3
- Authority
- DK
- Denmark
- Prior art keywords
- compound
- linker molecule
- branched linker
- branched linkers
- branched
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Detergent Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10048417A DE10048417A1 (de) | 2000-09-29 | 2000-09-29 | Verbindungen mit verzweigtem Linker |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1327146T3 true DK1327146T3 (da) | 2006-01-23 |
Family
ID=7658168
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01985752T DK1327146T3 (da) | 2000-09-29 | 2001-09-26 | Forbindelse med et forgrenet linkermolekyle |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20040086943A1 (da) |
| EP (1) | EP1327146B1 (da) |
| JP (1) | JP3647845B2 (da) |
| AT (1) | ATE304709T1 (da) |
| AU (1) | AU2002215904A1 (da) |
| CA (1) | CA2423916C (da) |
| DE (2) | DE10048417A1 (da) |
| DK (1) | DK1327146T3 (da) |
| ES (1) | ES2248405T3 (da) |
| WO (1) | WO2002027315A2 (da) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6858210B1 (en) | 1998-06-09 | 2005-02-22 | La Jolla Pharmaceutical Co. | Therapeutic and diagnostic domain 1 β2GPI polypeptides and methods of using same |
| EP2335728A1 (en) | 2001-05-11 | 2011-06-22 | Ludwig Institute for Cancer Research Ltd. | Specific binding proteins and uses thereof |
| US20100056762A1 (en) | 2001-05-11 | 2010-03-04 | Old Lloyd J | Specific binding proteins and uses thereof |
| US8114418B2 (en) | 2001-06-21 | 2012-02-14 | Dynavax Technologies Corporation | Chimeric immunomodulatory compounds and methods of using the same—IV |
| DE10227599B4 (de) * | 2002-06-20 | 2005-04-28 | Proteome Factory Ag | Verfahren und Reagenz zur spezifischen Identifizierung und Quantifizierung von einem oder mehreren Proteinen in einer Probe |
| ATE352632T1 (de) * | 2002-07-19 | 2007-02-15 | Mologen Ag | Dna-expressionskonstrukt zur multiplen genexpression |
| GB0329825D0 (en) * | 2003-12-23 | 2004-01-28 | Celltech R&D Ltd | Biological products |
| EP1780545B1 (en) * | 2004-07-30 | 2010-09-15 | Advanced Life Science Institute, Inc. | Probe complex |
| CA2627443C (en) | 2005-11-25 | 2013-10-01 | Mologen Ag | Dna constructs for specific inhibition of gene expression by rna interference |
| GB0607479D0 (en) * | 2006-04-13 | 2006-05-24 | Johnson Matthey Plc | Adhesion promoting compound |
| MX338185B (es) | 2007-01-25 | 2016-04-05 | Dana Farber Cancer Inst Inc | Uso de anticuerpos anti-egfr en el tratamiento de enfermedad mediada por egfr mutante. |
| WO2008115404A1 (en) | 2007-03-15 | 2008-09-25 | Ludwing Institute For Cancer Research | Treatment method using egfr antibodies and src inhibitors and related formulations |
| CN101896503B (zh) | 2007-08-14 | 2018-05-22 | 路德维格癌症研究所有限公司 | 靶向egf受体的单克隆抗体175及其衍生物和用途 |
| EP2318051A4 (en) * | 2008-07-14 | 2012-12-26 | Andrew Metters | IN VITRO DIAGNOSTIC MARKERS COMPRISING CARBON NANOPARTICLES AND KITS |
| CN103588801A (zh) * | 2013-12-02 | 2014-02-19 | 天津大港油田圣达科技有限公司 | 一种微量元素井间示踪剂的使用方法 |
| CN118362716A (zh) | 2018-12-28 | 2024-07-19 | 雅培制药有限公司 | 微粒上的单分子的直接检测 |
| CN115135680A (zh) * | 2019-12-18 | 2022-09-30 | 标准生物工具加拿大公司 | 用于信号放大的质谱细胞术试剂和方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK365785A (da) * | 1984-09-17 | 1986-03-18 | Hoffmann La Roche | Metalcomplexer |
| US5075447A (en) * | 1984-09-17 | 1991-12-24 | Hoffmann-La Roche Inc. | Ruthenium complexes useful as carriers for immunologically active materials |
| FR2579224B1 (fr) * | 1985-03-25 | 1987-05-22 | Genetica | Procede de preparation microbiologique de la serum-albumine humaine |
| US5750409A (en) * | 1991-11-18 | 1998-05-12 | Boehringer Mannheim Gmbh | Pentacyclic compounds and their use as absorption or fluorescent dyes |
| GB9215780D0 (en) * | 1992-07-24 | 1992-09-09 | Univ London Pharmacy | Peptide compounds |
| DE4310141A1 (de) * | 1993-03-29 | 1994-10-06 | Boehringer Mannheim Gmbh | Homobidentale trifunktionelle Linker |
| GB9407812D0 (en) * | 1994-04-20 | 1994-06-15 | Nycomed Salutar Inc | Compounds |
| EP0772616B1 (de) * | 1994-07-25 | 1999-12-15 | Roche Diagnostics GmbH | Hydrophile metallkomplexe |
| ES2171190T3 (es) * | 1994-07-25 | 2002-09-01 | Roche Diagnostics Gmbh | Peptidos marcados con haptenos. |
| ATE331952T1 (de) * | 1994-07-25 | 2006-07-15 | Roche Diagnostics Gmbh | Bestimmung von spezifischem immunglobulin unter verwendung multipler antigene |
| AU690315B2 (en) * | 1994-07-25 | 1998-04-23 | Boehringer Mannheim Gmbh | Metal complexes with charged linker |
| CA2195648A1 (en) * | 1994-07-25 | 1996-02-08 | Christoph Seidel | Metal chelate-labelled peptides |
| US5718915A (en) * | 1994-10-31 | 1998-02-17 | Burstein Laboratories, Inc. | Antiviral liposome having coupled target-binding moiety and hydrolytic enzyme |
| DE19519973A1 (de) * | 1995-05-31 | 1996-12-05 | Boehringer Mannheim Gmbh | Entstörungsreagenz für die Bestimmung eines Analyten mit einem lumineszenzfähigen Metallkomplex |
| US5714360A (en) * | 1995-11-03 | 1998-02-03 | Bsi Corporation | Photoactivatable water soluble cross-linking agents containing an onium group |
| WO1998019705A1 (en) * | 1996-11-05 | 1998-05-14 | Bristol-Myers Squibb Company | Branched peptide linkers |
| PT1061954E (pt) * | 1998-03-12 | 2004-10-29 | Nektar Therapeutics Al Corp | Derivados de poli(etileno glicol) com grupos reactivos proximos |
| DE19811582A1 (de) * | 1998-03-17 | 1999-09-23 | Roche Diagnostics Gmbh | Stabilisierung und Verstärkung von Elektrochemilumineszenz-Signalen |
| US6153655A (en) * | 1998-04-17 | 2000-11-28 | Enzon, Inc. | Terminally-branched polymeric linkers and polymeric conjugates containing the same |
| WO2000018583A1 (en) * | 1998-09-29 | 2000-04-06 | Hewlett-Packard Company | Method and apparatus for making booklets |
| GB2413081A (en) * | 2004-04-13 | 2005-10-19 | Sca Hygiene Prod Ab | Absorbant article with folded side flap portions and method of manufacture |
-
2000
- 2000-09-29 DE DE10048417A patent/DE10048417A1/de not_active Withdrawn
-
2001
- 2001-09-26 US US10/381,944 patent/US20040086943A1/en not_active Abandoned
- 2001-09-26 JP JP2002530643A patent/JP3647845B2/ja not_active Expired - Lifetime
- 2001-09-26 WO PCT/EP2001/011118 patent/WO2002027315A2/en active IP Right Grant
- 2001-09-26 AT AT01985752T patent/ATE304709T1/de active
- 2001-09-26 EP EP01985752A patent/EP1327146B1/en not_active Expired - Lifetime
- 2001-09-26 AU AU2002215904A patent/AU2002215904A1/en not_active Abandoned
- 2001-09-26 ES ES01985752T patent/ES2248405T3/es not_active Expired - Lifetime
- 2001-09-26 DK DK01985752T patent/DK1327146T3/da active
- 2001-09-26 CA CA002423916A patent/CA2423916C/en not_active Expired - Lifetime
- 2001-09-26 DE DE60113445T patent/DE60113445T2/de not_active Expired - Lifetime
-
2009
- 2009-02-13 US US12/370,886 patent/US20090264618A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE60113445T2 (de) | 2006-06-29 |
| JP3647845B2 (ja) | 2005-05-18 |
| WO2002027315A2 (en) | 2002-04-04 |
| EP1327146A2 (en) | 2003-07-16 |
| US20090264618A1 (en) | 2009-10-22 |
| US20040086943A1 (en) | 2004-05-06 |
| DE60113445D1 (de) | 2005-10-20 |
| EP1327146B1 (en) | 2005-09-14 |
| WO2002027315A3 (en) | 2002-07-11 |
| DE10048417A1 (de) | 2002-04-11 |
| ATE304709T1 (de) | 2005-09-15 |
| CA2423916C (en) | 2009-02-03 |
| CA2423916A1 (en) | 2002-04-04 |
| ES2248405T3 (es) | 2006-03-16 |
| JP2004510160A (ja) | 2004-04-02 |
| AU2002215904A1 (en) | 2002-04-08 |
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