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DK1307436T3 - Fremgangsmåde til fremstilling af baccatin III-derivater - Google Patents

Fremgangsmåde til fremstilling af baccatin III-derivater

Info

Publication number
DK1307436T3
DK1307436T3 DK01960578T DK01960578T DK1307436T3 DK 1307436 T3 DK1307436 T3 DK 1307436T3 DK 01960578 T DK01960578 T DK 01960578T DK 01960578 T DK01960578 T DK 01960578T DK 1307436 T3 DK1307436 T3 DK 1307436T3
Authority
DK
Denmark
Prior art keywords
preparation
baccatin iii
iii derivatives
derivatives
beta
Prior art date
Application number
DK01960578T
Other languages
English (en)
Inventor
Alessandro Pontiroli
Ezio Bombardelli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of DK1307436T3 publication Critical patent/DK1307436T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK01960578T 2000-08-10 2001-07-27 Fremgangsmåde til fremstilling af baccatin III-derivater DK1307436T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI001869A IT1318678B1 (it) 2000-08-10 2000-08-10 Procedimento per la preparazione di derivati della baccatina iii.
PCT/EP2001/008730 WO2002012215A1 (en) 2000-08-10 2001-07-27 Process for the preparation of baccatin iii derivatives

Publications (1)

Publication Number Publication Date
DK1307436T3 true DK1307436T3 (da) 2005-01-31

Family

ID=11445705

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01960578T DK1307436T3 (da) 2000-08-10 2001-07-27 Fremgangsmåde til fremstilling af baccatin III-derivater

Country Status (23)

Country Link
US (2) US6828445B2 (da)
EP (1) EP1307436B1 (da)
JP (1) JP4907043B2 (da)
KR (1) KR100853056B1 (da)
CN (3) CN1254470C (da)
AT (1) ATE277919T1 (da)
AU (2) AU2001282040B8 (da)
CA (1) CA2418829C (da)
CZ (1) CZ302810B6 (da)
DE (1) DE60106057T2 (da)
DK (1) DK1307436T3 (da)
ES (1) ES2228929T3 (da)
HK (2) HK1055964A1 (da)
HU (1) HU229316B1 (da)
IL (2) IL154330A0 (da)
IT (1) IT1318678B1 (da)
NO (1) NO328124B1 (da)
PL (1) PL200868B1 (da)
PT (1) PT1307436E (da)
RU (1) RU2264394C2 (da)
SI (1) SI1307436T1 (da)
SK (1) SK286653B6 (da)
WO (1) WO2002012215A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1320107B1 (it) * 2000-11-28 2003-11-18 Indena Spa Procedimento per la preparazione di derivati tassanici.
ITMI20012186A1 (it) 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14-beta-idrossi-baccatina iii-1,14-carbonato
ITMI20012185A1 (it) * 2001-10-19 2003-04-19 Indena Spa Procedimento per la preparazione della 14beta-idrossi-baccatina iii-1,14-carbonato
ITMI20021921A1 (it) * 2002-09-10 2004-03-11 Indena Spa Funzionalizzazione della posizione 14 dei nuclei tassanici e sintesi di nuovi derivati antitumorali.
US7446126B2 (en) * 2004-10-08 2008-11-04 Indena S.P.A. Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
ITMI20050614A1 (it) * 2005-04-12 2006-10-13 Indena Spa Processo per la purificazione della 10-deacetilbaccatina iii dalla 10-deacetil-2-debenzoil-2-pentenoilbaccatina iii
US20080151139A1 (en) * 2006-12-22 2008-06-26 Itt Manufacturing Enterprises, Inc. Addressable backlight for LCD panel
EP2080764B1 (en) 2008-01-18 2012-08-22 INDENA S.p.A. Solid forms of ortataxel

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698712A (en) 1992-03-06 1997-12-16 Indena S.P.A. Baccatine III derivatives
IT1275936B1 (it) * 1995-03-17 1997-10-24 Indena Spa Derivati della 10-deacetilbaccatina iii e della 10-deacetil-14b- idrossibaccatina iii loro metodo di preparazione e formulazioni
FR2732341A1 (fr) * 1995-03-27 1996-10-04 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
IT1275435B (it) * 1995-05-19 1997-08-07 Indena Spa Derivati della 10-desacetil-14beta-idrossibaccatina iii,loro metodo di preparazione e formulazioni che li contengono
AU2187799A (en) * 1998-01-26 1999-08-09 Hanmi Pharmaceutical Co., Ltd. Novel taxaneterpine compounds
IT1308636B1 (it) 1999-03-02 2002-01-09 Indena Spa Procedimento per la preparazione di tassani da 10-desacetilbaccatinaiii.
ITMI991483A1 (it) * 1999-07-06 2001-01-06 Indena Spa Derivati tassanici e procedimenti per la loro preparazione
IT1320107B1 (it) * 2000-11-28 2003-11-18 Indena Spa Procedimento per la preparazione di derivati tassanici.

Also Published As

Publication number Publication date
IL154330A0 (en) 2003-09-17
NO328124B1 (no) 2009-12-14
EP1307436A1 (en) 2003-05-07
RU2264394C2 (ru) 2005-11-20
US20050113585A1 (en) 2005-05-26
HUP0303832A2 (hu) 2004-03-01
ES2228929T3 (es) 2005-04-16
NO20030609D0 (no) 2003-02-07
CN1446207A (zh) 2003-10-01
CZ302810B6 (cs) 2011-11-23
HK1088325A1 (en) 2006-11-03
KR20030020454A (ko) 2003-03-08
JP4907043B2 (ja) 2012-03-28
PL360087A1 (en) 2004-09-06
SK286653B6 (sk) 2009-03-05
SK1592003A3 (en) 2003-07-01
US7078538B2 (en) 2006-07-18
PL200868B1 (pl) 2009-02-27
DE60106057T2 (de) 2006-02-23
AU2001282040B2 (en) 2005-09-15
KR100853056B1 (ko) 2008-08-19
PT1307436E (pt) 2004-11-30
CA2418829A1 (en) 2002-02-14
JP2004505961A (ja) 2004-02-26
ATE277919T1 (de) 2004-10-15
IT1318678B1 (it) 2003-08-27
AU2001282040B8 (en) 2006-01-19
CN1254470C (zh) 2006-05-03
IL154330A (en) 2006-12-31
WO2002012215A1 (en) 2002-02-14
CA2418829C (en) 2009-12-29
HU229316B1 (en) 2013-10-28
CN101130528A (zh) 2008-02-27
HUP0303832A3 (en) 2005-02-28
CZ2003365A3 (cs) 2003-06-18
AU8204001A (en) 2002-02-18
NO20030609L (no) 2003-02-07
SI1307436T1 (en) 2005-02-28
HK1055964A1 (en) 2004-01-30
US6828445B2 (en) 2004-12-07
DE60106057D1 (de) 2004-11-04
CN100349882C (zh) 2007-11-21
CN1736995A (zh) 2006-02-22
US20040014998A1 (en) 2004-01-22
ITMI20001869A0 (it) 2000-08-10
ITMI20001869A1 (it) 2002-02-10
EP1307436B1 (en) 2004-09-29

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