DK135683B - Analogous process for the preparation of 2,4-diamino-5-benzyl-pyrimidine derivatives or salts of these compounds. - Google Patents

Analogous process for the preparation of 2,4-diamino-5-benzyl-pyrimidine derivatives or salts of these compounds.

Info

Publication number: DK135683B
Authority: DK; Denmark
Prior art keywords: diamino; benzyl; salts; compounds; preparation
Prior art date: 1973-09-12

Application number

DK468374AA

Other languages

Danish (da)

Other versions

DK468374A (en

DK135683C (en

Inventor

Ivan Kompis

Gerald Rey-Bellet

Guido Zanetti

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-09-12

Filing date

1974-09-04

Publication date

1977-06-06

1974-09-04 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1975-05-12 Publication of DK468374A publication Critical patent/DK468374A/da

1976-07-05 Priority to DK304476A priority Critical patent/DK304476A/en

1977-06-06 Publication of DK135683B publication Critical patent/DK135683B/en

1977-11-14 Application granted granted Critical

1977-11-14 Publication of DK135683C publication Critical patent/DK135683C/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C07D239/49—Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Oncology (AREA)
Pharmacology & Pharmacy (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrrole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

DK468374AA 1973-09-12 1974-09-04 Analogous process for the preparation of 2,4-diamino-5-benzyl-pyrimidine derivatives or salts of these compounds. DK135683B (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
DK304476A DK304476A (en)	1973-09-12	1976-07-05	BENZYLPYRIMIDINES, THEIR MANUFACTURE AND USE

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH1305773A CH591456A5 (en)	1973-09-12	1973-09-12

Publications (3)

Publication Number	Publication Date
DK468374A DK468374A (en)	1975-05-12
DK135683B true DK135683B (en)	1977-06-06
DK135683C DK135683C (en)	1977-11-14

Family

ID=4388903

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK468374AA DK135683B (en)	1973-09-12	1974-09-04	Analogous process for the preparation of 2,4-diamino-5-benzyl-pyrimidine derivatives or salts of these compounds.

Country Status (28)

Country	Link
JP (1)	JPS6042238B2 (en)
AR (2)	AR207764A1 (en)
AT (1)	AT338797B (en)
BE (1)	BE819773A (en)
BR (1)	BR7407614D0 (en)
CA (1)	CA1037476A (en)
CH (1)	CH591456A5 (en)
CU (1)	CU34115A (en)
DD (2)	DD122785A5 (en)
DE (1)	DE2443682C2 (en)
DK (1)	DK135683B (en)
ES (7)	ES429949A1 (en)
FI (1)	FI58638C (en)
FR (1)	FR2242984B1 (en)
GB (3)	GB1484481A (en)
HK (1)	HK181A (en)
HU (1)	HU170427B (en)
IE (1)	IE40523B1 (en)
IL (1)	IL45510A (en)
LU (1)	LU70878A1 (en)
NL (1)	NL155827B (en)
NO (1)	NO140858C (en)
PH (1)	PH10643A (en)
PL (2)	PL97757B1 (en)
SE (1)	SE419443B (en)
SU (3)	SU577987A3 (en)
YU (3)	YU217874A (en)
ZA (1)	ZA745317B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4515948A (en) *	1973-09-12	1985-05-07	Hoffmann-La Roche Inc.	2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
EP0001633A1 (en) *	1977-10-18	1979-05-02	The Wellcome Foundation Limited	Processes for preparing tri-heterocyclic substituted methanes and their conversion into further intermediates useful in the preparation of pharmacologically active compounds
CH639273A5 (en)	1978-09-12	1983-11-15	Hoffmann La Roche	DIURETIC MEANS.
DE3250132C2 (en) *	1981-11-09	1997-01-16	Mallinckrodt Veterinary Inc	2,4-Di:amino-5-benzyl-pyrimidine derivs. prepn.
CH664960A5 (en) *	1981-11-09	1988-04-15	Wellcome Found	METHOD FOR PRODUCING SUBSTITUTED 2,4-DIAMINO-5-BENZYLPYRIMIDINES.
GB2180836A (en) *	1985-09-27	1987-04-08	William James Stephen Barker	Sunscreen
JPH0431685Y2 (en) *	1987-06-01	1992-07-30
CA1300166C (en) *	1987-12-03	1992-05-05	Alfredo Guerrato	Process for the preparation of a benzoic acid ester
US4900859A (en) *	1987-12-03	1990-02-13	Hoffman-La Roche Inc.	Process for 4-dimethylamino-3,5-dimethoxybenzaldehyde

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1103931B (en) *	1957-02-21	1961-04-06	Wellcome Found	Process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives
US3485840A (en) *	1964-11-12	1969-12-23	Hoffmann La Roche	2,4-diamino - 5 - (2',4',5'-substituted benzyl) pyrimidines,intermediates and processes

1973
- 1973-09-12 CH CH1305773A patent/CH591456A5/xx not_active IP Right Cessation
1974
- 1974-01-01 AR AR255569A patent/AR207764A1/en active
- 1974-08-06 YU YU02178/74A patent/YU217874A/en unknown
- 1974-08-19 ZA ZA00745317A patent/ZA745317B/en unknown
- 1974-08-21 CA CA207,509A patent/CA1037476A/en not_active Expired
- 1974-08-21 IL IL45510A patent/IL45510A/en unknown
- 1974-09-02 FI FI2561/74A patent/FI58638C/en active
- 1974-09-03 NL NL7411685.A patent/NL155827B/en not_active IP Right Cessation
- 1974-09-04 DK DK468374AA patent/DK135683B/en unknown
- 1974-09-06 PL PL1974173909A patent/PL97757B1/en unknown
- 1974-09-06 PL PL1974195308A patent/PL99159B1/en unknown
- 1974-09-09 SE SE7411382A patent/SE419443B/en unknown
- 1974-09-09 PH PH16253A patent/PH10643A/en unknown
- 1974-09-09 IE IE1870/74A patent/IE40523B1/en unknown
- 1974-09-10 DD DD190238A patent/DD122785A5/xx unknown
- 1974-09-10 LU LU70878A patent/LU70878A1/xx unknown
- 1974-09-10 JP JP49103536A patent/JPS6042238B2/en not_active Expired
- 1974-09-10 DD DD181015A patent/DD116824A5/xx unknown
- 1974-09-10 FR FR7430568A patent/FR2242984B1/fr not_active Expired
- 1974-09-11 CU CU34115A patent/CU34115A/en unknown
- 1974-09-11 AT AT735174A patent/AT338797B/en not_active IP Right Cessation
- 1974-09-11 GB GB39617/74A patent/GB1484481A/en not_active Expired
- 1974-09-11 GB GB47894/76A patent/GB1484483A/en not_active Expired
- 1974-09-11 SU SU7402058406A patent/SU577987A3/en active
- 1974-09-11 NO NO743271A patent/NO140858C/en unknown
- 1974-09-11 ES ES429949A patent/ES429949A1/en not_active Expired
- 1974-09-11 GB GB47893/76A patent/GB1484482A/en not_active Expired
- 1974-09-11 HU HUHO1718A patent/HU170427B/hu not_active IP Right Cessation
- 1974-09-11 BE BE148396A patent/BE819773A/en not_active IP Right Cessation
- 1974-09-12 DE DE2443682A patent/DE2443682C2/en not_active Expired
- 1974-09-12 BR BR7614/74A patent/BR7407614D0/en unknown
1975
- 1975-04-25 ES ES437008A patent/ES437008A1/en not_active Expired
- 1975-04-25 ES ES437009A patent/ES437009A1/en not_active Expired
- 1975-04-25 ES ES437012A patent/ES437012A1/en not_active Expired
- 1975-04-25 ES ES437011A patent/ES437011A1/en not_active Expired
- 1975-04-25 ES ES437007A patent/ES437007A1/en not_active Expired
- 1975-04-25 ES ES437013A patent/ES437013A1/en not_active Expired
- 1975-06-20 SU SU752145937A patent/SU609465A3/en active
- 1975-06-20 SU SU7502145932A patent/SU571189A3/en active
- 1975-06-30 AR AR259408A patent/AR211387Q/en unknown
1980
- 1980-11-27 YU YU3016/80A patent/YU37154B/en unknown
- 1980-11-27 YU YU3015/80A patent/YU37153B/en unknown
1981
- 1981-01-08 HK HK1/81A patent/HK181A/en unknown

Also Published As

Publication number	Publication date
YU217874A (en)	1982-06-18
FI256174A (en)	1975-03-13
ES437013A1 (en)	1977-04-01
HK181A (en)	1981-01-16
NO140858B (en)	1979-08-20
AR207764A1 (en)	1976-10-29
AU7263174A (en)	1976-02-26
YU37153B (en)	1984-08-31
SU577987A3 (en)	1977-10-25
NL155827B (en)	1978-02-15
GB1484482A (en)	1977-09-01
FR2242984B1 (en)	1977-11-04
NO140858C (en)	1979-11-28
PL97757B1 (en)	1978-03-30
DK468374A (en)	1975-05-12
ES437008A1 (en)	1977-04-01
IL45510A (en)	1978-08-31
PL99159B1 (en)	1978-06-30
LU70878A1 (en)	1976-08-19
SE7411382L (en)	1975-03-13
FR2242984A1 (en)	1975-04-04
ATA735174A (en)	1977-01-15
ES429949A1 (en)	1976-10-01
IE40523B1 (en)	1979-06-20
JPS5053385A (en)	1975-05-12
DE2443682A1 (en)	1975-03-20
SE419443B (en)	1981-08-03
SU571189A3 (en)	1977-08-30
ES437009A1 (en)	1977-04-01
PH10643A (en)	1977-07-22
JPS6042238B2 (en)	1985-09-20
YU37154B (en)	1984-08-31
ES437012A1 (en)	1977-04-01
GB1484483A (en)	1977-09-01
SU609465A3 (en)	1978-05-30
DE2443682C2 (en)	1983-11-10
AR211387Q (en)	1977-12-15
DK135683C (en)	1977-11-14
CH591456A5 (en)	1977-09-15
GB1484481A (en)	1977-09-01
NL7411685A (en)	1975-03-14
AT338797B (en)	1977-09-12
ES437007A1 (en)	1977-04-01
FI58638C (en)	1981-03-10
IE40523L (en)	1975-03-12
ES437011A1 (en)	1977-04-01
HU170427B (en)	1977-06-28
CA1037476A (en)	1978-08-29
YU301580A (en)	1983-04-27
DD122785A5 (en)	1976-11-05
IL45510A0 (en)	1974-11-29
BR7407614D0 (en)	1975-07-08
DD116824A5 (en)	1975-12-12
YU301680A (en)	1983-04-27
ZA745317B (en)	1975-11-26
CU21022L (en)	1981-09-09
NO743271L (en)	1975-04-07
BE819773A (en)	1975-03-11
FI58638B (en)	1980-11-28
CU34115A (en)	1983-10-04

Publication	Publication Date	Title
DK131725B (en)	1975-08-25	Analogous process for the preparation of 2,4-diaminoquinazolines or salts thereof.
DK132172B (en)	1975-11-03	Analogous process for the preparation of 6,7-benzomorphans or their salts.
DK138692B (en)	1978-10-16	Analogous process for the preparation of s-triazolo (4,3-b) pyridazines or salts thereof.
DK138791B (en)	1978-10-30	Analogous process for the preparation of 2,6-disubstituted phenylaminoguanidine compounds.
DK140461B (en)	1979-09-03	Analogous process for the preparation of 8-azapurin-6-ones or salts thereof.
DK136060B (en)	1977-08-08	Analogous process for the preparation of 3-substituted 1,4,5,6-tetrahydropyridines or salts thereof.
DK139678B (en)	1979-03-26	Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine.
DK128078B (en)	1974-02-25	Analogous process for the preparation of 1,2,3,4-tetrahydroisoquinoline derivatives or salts thereof.
DK138327B (en)	1978-08-14	Analogous process for the preparation of pyrido (1,2a) pyrimidine derivatives.
DK138020B (en)	1978-06-26	Analogous process for the preparation of pyrazolodiazepine compounds or salts thereof.
DK135683B (en)	1977-06-06	Analogous process for the preparation of 2,4-diamino-5-benzyl-pyrimidine derivatives or salts of these compounds.
DK124682B (en)	1972-11-13	Analogous process for the preparation of N-oxides of 2,4-diamino-5-benzylpyrimidines or acid addition salts of these compounds.
DK140406B (en)	1979-08-20	Process for the preparation of 2,2,6,6-tetramethyl-4-oxopiperidine.
DK139388B (en)	1979-02-12	Process for the preparation of 2-amino-4-hydroxy-7,7-dimethyl-7,8-dihydropteridines or tautomers thereof or salts of these compounds.
DK136470B (en)	1977-10-17	Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives or salts thereof.
DK136816B (en)	1977-11-28	Analogous process for the preparation of phenoxypropylamine derivatives or their salts.
DK138797B (en)	1978-10-30	Analogous process for the preparation of 1,4-benzodiazepine derivatives or N-oxides or salts thereof.
DK134233B (en)	1976-10-04	Analogous process for the preparation of substituted benzimidazolinones or triazaspiro- [4,5] -decan-4-ones or acid addition salts thereof.
DK138449B (en)	1978-09-11	Process for the preparation of D (-) - penicillamine or its salts.
DK133979B (en)	1976-08-23	Analogous process for the preparation of 5-methyl-10- (beta-alkylaminethyl) -dibenzo (b, f) -azepines or salts thereof.
DK135504B (en)	1977-05-09	Analogous process for the preparation of 6-substituted 3-carbethoxyhydrazinopyridazines or salts thereof.
DK140841B (en)	1979-11-26	Analogous process for the preparation of isoquinoline derivatives or salts thereof.
DK131374B (en)	1975-07-07	Process for the preparation of 1,4-benzodiazepine derivatives or salts thereof.
DK134486B (en)	1976-11-15	Analogous process for the preparation of 3-hydrazonomethyl-rifamycin derivatives or 25-desacetyl- or 16, 17, 18, 19, 28, 29-hexahydro derivatives thereof.
DK137797B (en)	1978-05-08	Analogous process for the preparation of 2,4-diamino-5-benzylpyrimidine derivatives or salts thereof.