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DK1215201T3 - Fremgangsmåde til fremstilling af aryloctanylamider - Google Patents

Fremgangsmåde til fremstilling af aryloctanylamider

Info

Publication number
DK1215201T3
DK1215201T3 DK01128462T DK01128462T DK1215201T3 DK 1215201 T3 DK1215201 T3 DK 1215201T3 DK 01128462 T DK01128462 T DK 01128462T DK 01128462 T DK01128462 T DK 01128462T DK 1215201 T3 DK1215201 T3 DK 1215201T3
Authority
DK
Denmark
Prior art keywords
chem
formula
compounds
removal
reaction
Prior art date
Application number
DK01128462T
Other languages
English (en)
Inventor
Daniel Bellus
Alessandro Dondoni
Original Assignee
Speedel Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Pharma Ag filed Critical Speedel Pharma Ag
Application granted granted Critical
Publication of DK1215201T3 publication Critical patent/DK1215201T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/16Preparation of optical isomers
    • C07C231/18Preparation of optical isomers by stereospecific synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK01128462T 2000-12-14 2001-12-06 Fremgangsmåde til fremstilling af aryloctanylamider DK1215201T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH24422000 2000-12-14

Publications (1)

Publication Number Publication Date
DK1215201T3 true DK1215201T3 (da) 2007-01-29

Family

ID=4569276

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01128462T DK1215201T3 (da) 2000-12-14 2001-12-06 Fremgangsmåde til fremstilling af aryloctanylamider

Country Status (8)

Country Link
US (2) US20020082302A1 (da)
EP (1) EP1215201B1 (da)
AT (1) ATE342887T1 (da)
CY (1) CY1107575T1 (da)
DE (1) DE60123911T2 (da)
DK (1) DK1215201T3 (da)
ES (1) ES2274847T3 (da)
PT (1) PT1215201E (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0212410D0 (en) * 2002-05-29 2002-07-10 Novartis Ag Organic compounds
AU2003238007A1 (en) * 2002-06-11 2003-12-22 Elan Pharmaceuticals, Inc. Methods of treating alzheimer's disease using aryl alkanoic acid amides
GB0327839D0 (en) * 2003-12-01 2003-12-31 Novartis Ag Organic compounds
GB0419361D0 (en) * 2004-08-31 2004-10-06 Novartis Ag Organic compounds
GB0511686D0 (en) * 2005-06-08 2005-07-13 Novartis Ag Organic compounds
GB0521083D0 (en) 2005-10-17 2005-11-23 Novartis Ag Organic compounds
GB2431651A (en) * 2005-10-25 2007-05-02 Novartis Ag Synthesis of aryl-octanoyl amide compounds
GB2431652A (en) * 2005-10-25 2007-05-02 Novartis Ag Alternative synthesis of aryl-octanoyl amide compounds
GB2431647A (en) * 2005-10-25 2007-05-02 Novartis Ag Synthesis of aryl-octanoyl amide compounds
GB2431654A (en) * 2005-10-25 2007-05-02 Novartis Ag Alternative synthesis of aryl-octanoyl amide compounds
GB2431644A (en) * 2005-10-25 2007-05-02 Novartis Ag Synthesis of aryl-octanoyl amide compounds
GB2431648A (en) * 2005-10-25 2007-05-02 Novartis Ag Alternative synthesis of aryl-octanoyl amide compounds
GB2431650A (en) * 2005-10-25 2007-05-02 Novartis Ag Alternative synthesis of aryl-octanoyl amide compounds
GB2431640A (en) * 2005-10-25 2007-05-02 Novartis Ag Alternative synthesis of aryl-octanoyl amide compounds
GB2431643A (en) * 2005-10-25 2007-05-02 Novartis Ag Synthesis of aryl-octanoyl amide compounds
GB2431646A (en) * 2005-10-25 2007-05-02 Novartis Ag Alternative synthesis of aryl-octanoyl amide compounds
GB2431645A (en) * 2005-10-25 2007-05-02 Novartis Ag Alternative synthesis of aryl-octanoyl amide compounds
GB0522789D0 (en) 2005-11-08 2005-12-14 Novartis Ag Organic compounds
EP2062874B1 (en) 2007-11-20 2014-12-17 KRKA, tovarna zdravil, d.d., Novo mesto Process and intermediates for the preparation of aliskiren
SI2189442T1 (sl) 2008-11-20 2015-03-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Postopek in intermediati za pripravo aliskirena
WO2011051853A1 (en) * 2009-10-29 2011-05-05 CarboDesign LLC Manufacturing process for preparing enaniomerically pure 8- aryloctanoic acid derivatives such as aliskiren
WO2011064790A1 (en) * 2009-11-30 2011-06-03 Avra Laboratories Pvt. Ltd A novel process for making aliskiren, its novel intermediates and certain novel compounds
US8703976B2 (en) 2011-10-02 2014-04-22 Milan Soukup Manufacturing process for 8-aryloctanoic acids such as Aliskiren
CN113546633B (zh) * 2021-07-27 2022-07-01 云南大学 一种镨基磁性催化剂及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY119161A (en) * 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities

Also Published As

Publication number Publication date
US6670507B2 (en) 2003-12-30
EP1215201A2 (en) 2002-06-19
EP1215201B1 (en) 2006-10-18
DE60123911T2 (de) 2007-05-31
PT1215201E (pt) 2007-02-28
CY1107575T1 (el) 2013-03-13
DE60123911D1 (de) 2006-11-30
EP1215201A3 (en) 2003-01-29
ES2274847T3 (es) 2007-06-01
US20020082302A1 (en) 2002-06-27
ATE342887T1 (de) 2006-11-15
US20030176717A1 (en) 2003-09-18

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