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DK1209151T3 - 4-substituerede piperidinderivativer - Google Patents

4-substituerede piperidinderivativer

Info

Publication number
DK1209151T3
DK1209151T3 DK00956885T DK00956885T DK1209151T3 DK 1209151 T3 DK1209151 T3 DK 1209151T3 DK 00956885 T DK00956885 T DK 00956885T DK 00956885 T DK00956885 T DK 00956885T DK 1209151 T3 DK1209151 T3 DK 1209151T3
Authority
DK
Denmark
Prior art keywords
ingrediates
piperide
substituted
provides
hydrates
Prior art date
Application number
DK00956885T
Other languages
Danish (da)
English (en)
Inventor
Takashi Kosasa
Yoichi Iimura
Original Assignee
Eisai R&D Man Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai R&D Man Co Ltd filed Critical Eisai R&D Man Co Ltd
Application granted granted Critical
Publication of DK1209151T3 publication Critical patent/DK1209151T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
DK00956885T 1999-09-01 2000-09-01 4-substituerede piperidinderivativer DK1209151T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP24711599 1999-09-01
PCT/JP2000/005968 WO2001016105A1 (fr) 1999-09-01 2000-09-01 Derives de piperidine 4-substituee

Publications (1)

Publication Number Publication Date
DK1209151T3 true DK1209151T3 (da) 2007-08-20

Family

ID=17158668

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00956885T DK1209151T3 (da) 1999-09-01 2000-09-01 4-substituerede piperidinderivativer

Country Status (10)

Country Link
US (1) US7091218B1 (fr)
EP (1) EP1209151B1 (fr)
AT (1) ATE360612T1 (fr)
CA (1) CA2382117C (fr)
CY (1) CY1106716T1 (fr)
DE (1) DE60034577T2 (fr)
DK (1) DK1209151T3 (fr)
ES (1) ES2284519T3 (fr)
PT (1) PT1209151E (fr)
WO (1) WO2001016105A1 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002002526A1 (fr) * 2000-07-03 2002-01-10 Eisai Co., Ltd. Compositions pharmaceutiques servant a stabiliser la tension intraoculaire
KR100579813B1 (ko) * 2001-10-16 2006-05-12 주식회사 에스티씨나라 피페리딘 유도체, 이의 제조방법 및 이를 포함하는 치매치료용 약학적 조성물
BR0215389A (pt) 2001-12-28 2004-10-26 Takeda Chemical Industries Ltd Agente preventivo ou terapêutico para distúrbio urinário, método para prevenir ou tratar distúrbio urinário, uso de um composto, composto, pró-droga, processo para preparar o composto, medicamento, e, método para triar um composto
US20050107432A1 (en) * 2002-01-22 2005-05-19 Yoichi Iimura Sigma receptor binder containing indanone derivative
HUP0401850A3 (en) * 2004-09-15 2008-03-28 Egis Gyogyszergyar Nyilvanosan Donepezil salts for producing pharmaceutical composition
DE102004046497A1 (de) * 2004-09-23 2006-04-06 Helm Ag Donepezil-Salze
JP2010512328A (ja) 2006-12-11 2010-04-22 レビバ ファーマシューティカルズ,インコーポレーテッド インダノン系コリンエステラーゼ阻害薬の組成物、合成および使用方法
US9249098B2 (en) * 2012-07-10 2016-02-02 Xueheng Cheng Derivatives of donepezil
CN103787954B (zh) 2012-10-26 2016-01-20 中国科学院上海药物研究所 一类氟取代的环状胺类化合物及其制备方法、药物组合物和用途
CA2891122C (fr) 2012-11-14 2021-07-20 The Johns Hopkins University Methodes et compositions pour le traitement de la schizophrenie
CA2904767C (fr) 2013-03-15 2022-06-21 Agenebio, Inc. Procedes et compositions pour ameliorer la fonction cognitive
EP2968237A4 (fr) 2013-03-15 2016-08-31 Univ Johns Hopkins Procédés et compositions pour améliorer la fonction cognitive
US10159648B2 (en) 2015-05-22 2018-12-25 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000319257A (ja) 1969-01-06 2000-11-21 Eisai Co Ltd 1−ベンジル−4−[(5,6−ジメトキシ−2−フルオロ−1−インダノン)−2−イル]メチルピペリジン
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
PL171915B1 (pl) 1991-03-28 1997-06-30 Eisai Co Ltd Sposób wytwarzania pochodnych aminy heterocyklicznej PL PL PL PL PL PL PL
US5750542A (en) 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
CA2116117A1 (fr) 1991-08-22 1993-03-04 Hiroyuki Sueoka Compose de type benzisoxazole et son utilisation
JPH09268176A (ja) 1996-04-01 1997-10-14 Eisai Co Ltd アラルキルピペリジン誘導体
CN1163224C (zh) 1998-09-30 2004-08-25 武田药品工业株式会社 改善膀胱排泄能力的药物
US20020177593A1 (en) 1998-09-30 2002-11-28 Yuji Ishihara Agents and crystals for improving excretory potency of urinary bladder
AU2825600A (en) 1999-03-03 2000-09-21 Eisai Co. Ltd. Fluorides of 4-substituted piperidine derivatives
US6277866B1 (en) 1999-03-03 2001-08-21 Eisai Co., Ltd. 1-benzyl-4[(5,6-dimethoxy-2-fluoro-1-indanon)-2-yl]methylpiperidine
WO2000057880A1 (fr) 1999-03-29 2000-10-05 Schering Corporation Procedes et compositions pour traiter des troubles allergiques et troubles associes au moyen de descarboethoxyloratadine fluoree
WO2002002526A1 (fr) 2000-07-03 2002-01-10 Eisai Co., Ltd. Compositions pharmaceutiques servant a stabiliser la tension intraoculaire
IL150982A (en) * 2002-07-30 2007-02-11 Ori Lerman Process for making Donafzil

Also Published As

Publication number Publication date
EP1209151A1 (fr) 2002-05-29
CA2382117C (fr) 2009-11-10
ATE360612T1 (de) 2007-05-15
CA2382117A1 (fr) 2001-03-08
DE60034577D1 (de) 2007-06-06
DE60034577T2 (de) 2007-12-27
US7091218B1 (en) 2006-08-15
PT1209151E (pt) 2007-05-31
EP1209151B1 (fr) 2007-04-25
ES2284519T3 (es) 2007-11-16
CY1106716T1 (el) 2012-05-23
EP1209151A4 (fr) 2004-12-29
WO2001016105A1 (fr) 2001-03-08

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