[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DK1206567T3 - In vivo höj-kapacitet toksikologisk screeningsfremgangsmåde - Google Patents

In vivo höj-kapacitet toksikologisk screeningsfremgangsmåde

Info

Publication number
DK1206567T3
DK1206567T3 DK00952321T DK00952321T DK1206567T3 DK 1206567 T3 DK1206567 T3 DK 1206567T3 DK 00952321 T DK00952321 T DK 00952321T DK 00952321 T DK00952321 T DK 00952321T DK 1206567 T3 DK1206567 T3 DK 1206567T3
Authority
DK
Denmark
Prior art keywords
subject
screening method
capacity
libraries
high throughput
Prior art date
Application number
DK00952321T
Other languages
English (en)
Inventor
Patrick Fogarty
Original Assignee
Tosk Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/472,654 external-priority patent/US6365129B1/en
Application filed by Tosk Inc filed Critical Tosk Inc
Application granted granted Critical
Publication of DK1206567T3 publication Critical patent/DK1206567T3/da

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms
    • G01N33/5085Supracellular entities, e.g. tissue, organisms of invertebrates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5014Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082Supracellular entities, e.g. tissue, organisms

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK00952321T 1999-08-04 2000-07-31 In vivo höj-kapacitet toksikologisk screeningsfremgangsmåde DK1206567T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14720099P 1999-08-04 1999-08-04
US09/472,654 US6365129B1 (en) 1999-08-04 1999-12-27 Invivo high throughput toxicology screening method
PCT/US2000/020849 WO2001011076A1 (en) 1999-08-04 2000-07-31 In vivo high throughput toxicology screening method

Publications (1)

Publication Number Publication Date
DK1206567T3 true DK1206567T3 (da) 2009-05-11

Family

ID=26844683

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00952321T DK1206567T3 (da) 1999-08-04 2000-07-31 In vivo höj-kapacitet toksikologisk screeningsfremgangsmåde

Country Status (8)

Country Link
EP (1) EP1206567B1 (da)
AT (1) ATE420354T1 (da)
AU (1) AU781138B2 (da)
CA (1) CA2381144C (da)
DE (1) DE60041337D1 (da)
DK (1) DK1206567T3 (da)
ES (1) ES2319959T3 (da)
WO (1) WO2001011076A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7415358B2 (en) 2001-05-22 2008-08-19 Ocimum Biosolutions, Inc. Molecular toxicology modeling
US7447594B2 (en) 2001-07-10 2008-11-04 Ocimum Biosolutions, Inc. Molecular cardiotoxicology modeling
US7469185B2 (en) 2002-02-04 2008-12-23 Ocimum Biosolutions, Inc. Primary rat hepatocyte toxicity modeling
WO2005069872A2 (en) * 2004-01-15 2005-08-04 Washington University High throughput pharmaceutical screening using drosophila

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254799A (en) * 1985-01-18 1993-10-19 Plant Genetic Systems N.V. Transformation vectors allowing expression of Bacillus thuringiensis endotoxins in plants
US5180838A (en) * 1986-08-26 1993-01-19 Her Majesty The Queen As Represented By The Minister Of National Defense Of Her Majesty's Canadian Government Phototoxic compounds for use as insect control agents
DE3715114A1 (de) * 1987-05-06 1988-11-17 Krause Hans Verfahren und einrichtung zum toxizitaetsnachweis in oberflaechengewaessern sowie in trink- und brauchwasser
US5204100A (en) * 1991-02-01 1993-04-20 Ciba-Geigy Corporation Baciullus thuringiensis strains active against coleopteran insects
UA48104C2 (uk) * 1991-10-04 2002-08-15 Новартіс Аг Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника
IL104419A0 (en) * 1992-01-24 1993-05-13 Fmc Corp Insecticidally effective peptides
CA2111521A1 (en) * 1993-12-15 1995-06-16 Stroud Water Research Center, Inc. Mayfly centroptilum triangulifer as a bioassay organism
US6063756A (en) * 1996-09-24 2000-05-16 Monsanto Company Bacillus thuringiensis cryET33 and cryET34 compositions and uses therefor
US6548733B2 (en) * 1998-12-21 2003-04-15 The Genetics Company, Inc. Function-based small molecular weight compound screening system in drosophila melanogaster

Also Published As

Publication number Publication date
CA2381144A1 (en) 2001-02-15
CA2381144C (en) 2012-05-01
EP1206567A1 (en) 2002-05-22
EP1206567B1 (en) 2009-01-07
ES2319959T3 (es) 2009-05-18
ATE420354T1 (de) 2009-01-15
WO2001011076A1 (en) 2001-02-15
AU6504300A (en) 2001-03-05
EP1206567A4 (en) 2005-11-23
DE60041337D1 (de) 2009-02-26
AU781138B2 (en) 2005-05-05

Similar Documents

Publication Publication Date Title
Latypov et al. Assignment of the absolute configuration of β-chiral primary alcohols by NMR: scope and limitations
WO2003029264A3 (en) 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof
DE60040677D1 (de) Verbessertes toxizität-screening verfahren
ATE234268T1 (de) Synthese von n-substituierten oligomeren
ATE395041T1 (de) Zusammensetzungen enthaltend mindestens ein polyamid, mindestens einen inerten füller und wachs
Payne et al. Development of an injectable, in situ crosslinkable, degradable polymeric carrier for osteogenic cell populations. Part 3. Proliferation and differentiation of encapsulated marrow stromal osteoblasts cultured on crosslinking poly (propylene fumarate)
WO1999065712A3 (en) Glycosulfopeptides and methods of synthesis and use thereof
CY1114303T1 (el) Νεο οξινο θειικο αλας
WO2007012695A3 (en) Tissue carbohydrate compositions and analysis thereof
Hixon et al. Nitrogen isotope (δ15N) patterns for amino acids in lemur bones are inconsistent with aridity driving megafaunal extinction in south‐western Madagascar
DK1206567T3 (da) In vivo höj-kapacitet toksikologisk screeningsfremgangsmåde
DK1077218T3 (da) Peptidomimetiske forbindelser omfattende RGD-sekvenser, som er nyttige som integrininhibitorer
DE112007000484B4 (de) Stabil isotopenmarkierte aliphatische Aminosäuren, Verfahren zum Einbringen von diesen in ein Zielprotein und Verfahren zur NMR-Konformationsanalyse von Proteinen
Narasimhan et al. QSAR studies of antibacterial ricinoleic acid derivatives
WO2000006525A3 (en) Synthesis of combinatorial libraries of compounds reminiscent of natural products
EP1146030A3 (en) Combinatorial synthesis and analysis of organometallic compounds and catalysts
Joergensen et al. The electronic structure of. beta.-thioxoketones. A photoelectron spectroscopic study of the enol-enethiol tautomerism of thioacetylacetone and related compounds
FR2852959B1 (fr) Nouveaux derives de cyclodextrines, leur procede de preparation et leur utilisation notamment pour solubilisation de substances pharmacologiquement actives
ATE494371T1 (de) Nukleinsäureleitern
Kuo et al. Biosynthesis of the pipecolate moiety of marcfortine A
DE60023544D1 (de) Zusammensetzungen enthaltend eine kombination von defi und modifizierten defi und verfahren zur herstellung
EA200800003A1 (ru) Фунгицидные комбинации биологически активных веществ
ATE306559T1 (de) Verfahren zum screenen von verbindungen mit bioaktivität in organgeweben
Joergensen et al. Search for a trans-disulfide: structural analysis of di-tert-adamantyl disulfide by photoelectron spectroscopy, derivation of. sigma. I (t-Ad), and molecular mechanics calculations for related bulky disulfides
DE69421531D1 (de) Verwendung von rosmanolderivaten zur herstellung von antiradikalischen und/oder antilipoperoxidativen und/oder hepatotropen arzneistoffen