DK1292710T3 - Fremgangsmåde til matrix-screening - Google Patents
Fremgangsmåde til matrix-screeningInfo
- Publication number
- DK1292710T3 DK1292710T3 DK01943634T DK01943634T DK1292710T3 DK 1292710 T3 DK1292710 T3 DK 1292710T3 DK 01943634 T DK01943634 T DK 01943634T DK 01943634 T DK01943634 T DK 01943634T DK 1292710 T3 DK1292710 T3 DK 1292710T3
- Authority
- DK
- Denmark
- Prior art keywords
- repertoires
- repertoire
- screening method
- combining
- members
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B30/00—Methods of screening libraries
- C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
- B01L3/0244—Drop counters; Drop formers using pins
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
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- Food Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nanotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Composite Materials (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Materials Engineering (AREA)
- Plant Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0015443A GB0015443D0 (en) | 2000-06-23 | 2000-06-23 | Matrix screening method |
GB0026099A GB0026099D0 (en) | 2000-10-25 | 2000-10-25 | Matrix screening method |
US24685100P | 2000-11-08 | 2000-11-08 | |
PCT/GB2001/002831 WO2001098534A2 (en) | 2000-06-23 | 2001-06-22 | Matrix screening method |
Publications (1)
Publication Number | Publication Date |
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DK1292710T3 true DK1292710T3 (da) | 2007-12-27 |
Family
ID=27255773
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK01943634T DK1292710T3 (da) | 2000-06-23 | 2001-06-22 | Fremgangsmåde til matrix-screening |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1292710B1 (da) |
JP (1) | JP2004501379A (da) |
AT (1) | ATE371749T1 (da) |
AU (1) | AU2001266172A1 (da) |
CA (1) | CA2410857A1 (da) |
DE (1) | DE60130211T2 (da) |
DK (1) | DK1292710T3 (da) |
ES (1) | ES2292596T3 (da) |
PT (1) | PT1292710E (da) |
WO (1) | WO2001098534A2 (da) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
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US20020115068A1 (en) * | 2000-06-23 | 2002-08-22 | Ian Tomlinson | Matrix screening method |
US6800453B2 (en) | 2001-01-23 | 2004-10-05 | President And Fellows Of Harvard College | Nucleic-acid programmable protein arrays |
US8178316B2 (en) | 2006-06-29 | 2012-05-15 | President And Fellows Of Harvard College | Evaluating proteins |
US8716437B2 (en) | 2007-12-07 | 2014-05-06 | Steven A. Goldstein | Identification of toxin ligands |
BRPI1013012A2 (pt) | 2009-06-02 | 2016-10-18 | Opko Health Inc | identificação de pequenas moléculas reconhecidas por anticorpos em indivíduos com doenças neurodegenerativas |
WO2011047257A1 (en) | 2009-10-16 | 2011-04-21 | The Board Of Regents Of The University Of Texas System | Compositions and methods for producing cyclic peptoid libraries |
SG11201505663YA (en) * | 2013-01-24 | 2015-08-28 | Scripps Korea Antibody Inst | Protein combination-based fv library, and preparation method therefor |
US10988759B2 (en) | 2016-01-15 | 2021-04-27 | University Of Washington | High throughput protein-protein interaction screening in yeast liquid culture |
EP4150073A1 (en) | 2020-05-11 | 2023-03-22 | A-Alpha Bio, Inc. | High-throughput screening methods to identify small molecule targets |
US20220251543A1 (en) | 2020-06-01 | 2022-08-11 | A-Alpha Bio, Inc. | Methods for characterizing and engineering protein-protein interactions |
WO2024071112A1 (ja) * | 2022-09-27 | 2024-04-04 | 国立大学法人浜松医科大学 | 抗体の製造方法 |
Family Cites Families (3)
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ATE262374T1 (de) * | 1991-11-22 | 2004-04-15 | Affymetrix Inc | Kombinatorische strategien für polymersynthese |
DE69822510T2 (de) * | 1997-11-27 | 2005-03-24 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Identifizierung und charakterisierung von interagierenden molekülen |
JP2003503067A (ja) * | 1999-06-26 | 2003-01-28 | オデュッセイ・ファーマシューティカルズ,インコーポレイテッド | 最適化された蛋白質−蛋白質相互作用のインビボライブラリー対ライブラリー選択 |
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2001
- 2001-06-22 AU AU2001266172A patent/AU2001266172A1/en not_active Abandoned
- 2001-06-22 WO PCT/GB2001/002831 patent/WO2001098534A2/en active IP Right Grant
- 2001-06-22 PT PT01943634T patent/PT1292710E/pt unknown
- 2001-06-22 DK DK01943634T patent/DK1292710T3/da active
- 2001-06-22 CA CA002410857A patent/CA2410857A1/en not_active Abandoned
- 2001-06-22 DE DE60130211T patent/DE60130211T2/de not_active Expired - Fee Related
- 2001-06-22 EP EP01943634A patent/EP1292710B1/en not_active Expired - Lifetime
- 2001-06-22 AT AT01943634T patent/ATE371749T1/de not_active IP Right Cessation
- 2001-06-22 JP JP2002504682A patent/JP2004501379A/ja not_active Withdrawn
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Also Published As
Publication number | Publication date |
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JP2004501379A (ja) | 2004-01-15 |
CA2410857A1 (en) | 2001-12-27 |
WO2001098534A3 (en) | 2002-05-30 |
EP1292710B1 (en) | 2007-08-29 |
ATE371749T1 (de) | 2007-09-15 |
EP1292710A2 (en) | 2003-03-19 |
AU2001266172A1 (en) | 2002-01-02 |
PT1292710E (pt) | 2007-12-04 |
WO2001098534A2 (en) | 2001-12-27 |
DE60130211D1 (de) | 2007-10-11 |
ES2292596T3 (es) | 2008-03-16 |
DE60130211T2 (de) | 2008-05-29 |
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