[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DK1137400T3 - Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode - Google Patents

Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode

Info

Publication number
DK1137400T3
DK1137400T3 DK99963398T DK99963398T DK1137400T3 DK 1137400 T3 DK1137400 T3 DK 1137400T3 DK 99963398 T DK99963398 T DK 99963398T DK 99963398 T DK99963398 T DK 99963398T DK 1137400 T3 DK1137400 T3 DK 1137400T3
Authority
DK
Denmark
Prior art keywords
peptide
preparation
compositions containing
extended release
subcutaneous implants
Prior art date
Application number
DK99963398T
Other languages
English (en)
Inventor
Alain Maquin
Patrice Mauriac
Pierre Marion
Original Assignee
Mediolanum Pharmaceuticals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mediolanum Pharmaceuticals Ltd filed Critical Mediolanum Pharmaceuticals Ltd
Application granted granted Critical
Publication of DK1137400T3 publication Critical patent/DK1137400T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK99963398T 1998-12-10 1999-12-06 Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode DK1137400T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002655A IT1304152B1 (it) 1998-12-10 1998-12-10 Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato
PCT/EP1999/009536 WO2000033809A1 (en) 1998-12-10 1999-12-06 Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extended release period

Publications (1)

Publication Number Publication Date
DK1137400T3 true DK1137400T3 (da) 2004-03-22

Family

ID=11381206

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99963398T DK1137400T3 (da) 1998-12-10 1999-12-06 Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode

Country Status (16)

Country Link
US (1) US6620422B1 (da)
EP (1) EP1137400B1 (da)
JP (1) JP4607329B2 (da)
KR (1) KR100676844B1 (da)
CN (1) CN1149975C (da)
AT (1) ATE253893T1 (da)
AU (1) AU757898C (da)
BR (1) BR9916053B1 (da)
CA (1) CA2354034C (da)
DE (1) DE69912836T2 (da)
DK (1) DK1137400T3 (da)
ES (1) ES2211211T3 (da)
IT (1) IT1304152B1 (da)
PT (1) PT1137400E (da)
TW (1) TW561053B (da)
WO (1) WO2000033809A1 (da)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1408876A4 (en) 2001-06-22 2004-09-22 Durect Corp ZERO ORDER COAXIAL IMPLANTS WITH EXTENDED RELEASE
JP4490095B2 (ja) 2001-06-29 2010-06-23 メドグラフト マイクロテック インコーポレイテッド 生体分解性の注入可能な移植物およびそれに関連する製造方法ならびに使用方法
KR100885070B1 (ko) * 2002-05-08 2009-02-25 재단법인서울대학교산학협력재단 Ｐｌｇａ에 특이적으로 부착하는 올리고 펩타이드
KR101139112B1 (ko) 2002-06-25 2012-04-30 다케다 야쿠힌 고교 가부시키가이샤 서방성 조성물의 제조 방법
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
ES2350123T3 (es) 2003-01-28 2011-01-18 Ironwood Pharmaceuticals, Inc. Composiciones para el tratamiento de trastornos gastrointestinales.
GB0304726D0 (en) * 2003-03-01 2003-04-02 Ardana Bioscience Ltd New Process
ITMI20031302A1 (it) 2003-06-26 2004-12-27 Mediolanum Pharmaceuticals Ltd Uso di etanolo come plasticizzante per preparare impianti sottocutanei contenenti principi attivi termolabili dispersi in una matrice di plga.
DE602004007802T2 (de) * 2003-06-26 2008-04-17 Mediolanum Pharmaceuticals Ltd. Subcutane implantate mit begrenzter initialer wirkstoff-freisetzung und deren anschliessende lineare veränderliche verlängerte freisetzung
TWI357815B (en) * 2003-06-27 2012-02-11 Euro Celtique Sa Multiparticulates
US7314938B2 (en) 2003-11-05 2008-01-01 Sunesis Pharmaceuticals, Inc. Modulators of cellular adhesion
US20060003008A1 (en) * 2003-12-30 2006-01-05 Gibson John W Polymeric devices for controlled release of active agents
FR2865938B1 (fr) * 2004-02-05 2006-06-02 Sod Conseils Rech Applic Formulation retard solide comprenant de l'acetate de triptoreline
AU2005325213B2 (en) 2004-08-04 2010-10-07 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
WO2006071208A1 (en) * 2004-12-23 2006-07-06 Durect Corporation Polymeric implants, preferably containing a mixture of peg and plg, for controlled release of a gnrh
US8168655B2 (en) * 2005-05-17 2012-05-01 Sarcode Bioscience Inc. Compositions and methods for treatment of eye disorders
ITMI20061545A1 (it) * 2006-08-02 2008-02-03 Mediolanum Pharmaceuticals Ltd Particelle in grado di rilasciare il principio attivo per un periodo prolungato di tempo
ITMI20061538A1 (it) * 2006-08-02 2008-02-03 Mediolanum Pharmaceuticals Ltd Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo
ITMI20061539A1 (it) * 2006-08-02 2008-02-03 Mediolanum Pharmaceuticals Ltd Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo
CN101209238B (zh) * 2006-12-27 2012-05-09 辽宁省计划生育科学研究院 含孕二烯酮的生物降解型长效皮下避孕埋植剂及其制备
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EA020466B1 (ru) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Агонисты гуанилатциклазы, пригодные для лечения желудочно-кишечных нарушений, воспаления, рака и других заболеваний
US8067028B2 (en) * 2007-08-13 2011-11-29 Confluent Surgical Inc. Drug delivery device
EP3167886B1 (en) 2007-10-19 2020-08-05 Novartis AG Compositions and methods for treatment of macular edema
US8728528B2 (en) 2007-12-20 2014-05-20 Evonik Corporation Process for preparing microparticles having a low residual solvent volume
CN102065893A (zh) * 2008-04-15 2011-05-18 萨可德公司 Lfa-1拮抗剂向胃肠系统的递送
US8080562B2 (en) * 2008-04-15 2011-12-20 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
EP2246063A1 (en) * 2009-04-29 2010-11-03 Ipsen Pharma S.A.S. Sustained release formulations comprising GnRH analogues
US8378105B2 (en) * 2009-10-21 2013-02-19 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
WO2011161531A1 (en) 2010-06-24 2011-12-29 Torrent Pharmaceuticals Limited Pharmaceutical composition containing goserelin for in-situ implant
WO2012151343A1 (en) 2011-05-04 2012-11-08 Balance Therapeutics, Inc. Pentylenetetrazole derivatives
DE102011114864A1 (de) 2011-10-05 2013-04-11 Acino Ag Verfahren zur Herstellung einer homogenen Pulvermischung und Verfahren zur Herstellung eines Implantats sowie Implantat
CN104797574B (zh) 2012-07-25 2019-11-22 原生质生物科学股份有限公司 Lfa-1抑制剂及其多晶型物
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CN103446041B (zh) * 2013-08-27 2015-06-10 青岛东辉医药科技发展有限公司 一种亮丙瑞林缓控释药棒及其制备方法
MY176976A (en) 2013-10-10 2020-08-28 Bausch Health Ireland Ltd Agonists of guanylate cyclase useful for the treatment of opioid induced dysfunctions
CN105287390A (zh) * 2015-11-20 2016-02-03 北京博恩特药业有限公司 一种长效醋酸亮丙瑞林微球及其制备方法
CN105267153B (zh) * 2015-11-27 2018-05-11 上海苏豪逸明制药有限公司 一种曲普瑞林缓释微粒及其制备方法
CN108884130B (zh) 2016-01-11 2022-09-13 博士医疗爱尔兰有限公司 用于治疗溃疡性结肠炎的制剂和方法
CN105878174B (zh) * 2016-04-26 2021-06-29 广州帝奇医药技术有限公司 一种固体分散体及其制备方法与应用
CN107281493A (zh) * 2017-06-20 2017-10-24 苏州乔纳森新材料科技有限公司 一种聚乳酸‑聚乙醇酸共聚复合材料及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2209937B (en) * 1987-09-21 1991-07-03 Depiopharm S A Water insoluble polypeptides
CH679207A5 (da) * 1989-07-28 1992-01-15 Debiopharm Sa
AU653771B2 (en) * 1991-01-03 1994-10-13 Alkermes Controlled Therapeutics, Inc. Stabilization of proteins by cationic biopolymers
PT99989A (pt) 1991-01-09 1994-05-31 Alza Corp Dispositivos biodegradaveis e composicoes para libertacao difusivel de agentes
CH683149A5 (fr) * 1991-07-22 1994-01-31 Debio Rech Pharma Sa Procédé pour la préparation de microsphères en matériau polymère biodégradable.
US5945128A (en) * 1996-09-04 1999-08-31 Romano Deghenghi Process to manufacture implants containing bioactive peptides
BR9713702A (pt) * 1996-12-12 2000-10-31 Dds Drug Delivery Service Ges Preparado na forma de um composto coadjuvante de material matriz contendo opcionalmente substância ativa

Also Published As

Publication number Publication date
JP2002531486A (ja) 2002-09-24
TW561053B (en) 2003-11-11
EP1137400B1 (en) 2003-11-12
EP1137400A1 (en) 2001-10-04
ITMI982655A1 (it) 2000-06-10
DE69912836T2 (de) 2004-11-11
CA2354034A1 (en) 2000-06-15
DE69912836D1 (de) 2003-12-18
WO2000033809A1 (en) 2000-06-15
US6620422B1 (en) 2003-09-16
BR9916053A (pt) 2001-09-04
PT1137400E (pt) 2004-03-31
KR20010082310A (ko) 2001-08-29
JP4607329B2 (ja) 2011-01-05
AU1971100A (en) 2000-06-26
CA2354034C (en) 2009-01-27
BR9916053B1 (pt) 2011-04-19
ES2211211T3 (es) 2004-07-01
KR100676844B1 (ko) 2007-01-31
AU757898C (en) 2003-12-18
IT1304152B1 (it) 2001-03-08
CN1149975C (zh) 2004-05-19
CN1329485A (zh) 2002-01-02
ATE253893T1 (de) 2003-11-15
AU757898B2 (en) 2003-03-13

Similar Documents

Publication Publication Date Title
DK1137400T3 (da) Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode
MY118835A (en) Sustained release compositions and the process for their preparation
DE69531741D1 (de) Verbindungen und zusammensetzungen zur verabreichung aktiver stoffe
DK0728148T3 (da) Forbedrede immunogene sammensætninger mod humant gastrin 17
ATE393831T1 (de) Zusammensetzung zur in vivo erzeugung von therapeutischen produkten
FI953378A (fi) Sytokiiniä pidättävät aineet
MX9705710A (es) Compuestos con propiedades de liberacion de la hormona del crecimiento.
TR200002299T2 (tr) Epotilon kompozisyonları.
ATE383169T1 (de) Komponente und zusammensetzungen zur verabreichung von wirkstoffen
ATE329897T1 (de) Verbindungen und zusammensetzungen zur verabreichung aktiven substanzen
IL109403A0 (en) Oral drug delivery compositions and methods
UA72915C2 (uk) Поживна ентеральна композиція, призначена для підтримки зростання та дозрівання недорозвинених шлунково-кишкових трактів у молодих ссавців та її застосування
ATE187740T1 (de) Modifizierte proteine und peptide enthaltende pharmazeutische mittel
ATE252375T1 (de) Bioabbaubare mikropartikeln mit verzögerter wirkstofffreisetzung
ATE281155T1 (de) Medikamentöse verabreichung von proteinen aus polymergemischen
JO1992B1 (en) Fixed pharmaceutical compounds based on the derivatives of quinpristine and dalphopristine materials and their preparation process
SG142165A1 (en) Biologically active peptides
BG103905A (en) New bpc peptide salts with organoprotective activity, method for their preparation and application in medicine
HK1047228A1 (en) Endoparasiticidal agents
TR200200599T2 (tr) İnsan insülini monomerik analogları.
ATE208627T1 (de) Orale zusammensetzungen mit niedrigdosierten zytotoxischen proteinen
DE60010230D1 (de) Pharmazeutische zusammensetzung von hydrophob modifizierten hedgehog-proteinen und deren verwendung
DE602004019141D1 (de) Isoleucyl-valyl-threonyl-asparaginyl-threonyl-threonin (ivtntt) enthaltende biologisch wirksame peptide
MX9604539A (es) Aminoacidos modificados para la distribucion de farmaco.
NZ335409A (en) Use of a burst free controlled release poly(lactide/glycolide) microcapsule pharmaceutical formulation