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DK1115725T3 - Tetrahydropyridoethere - Google Patents

Tetrahydropyridoethere

Info

Publication number
DK1115725T3
DK1115725T3 DK99948776T DK99948776T DK1115725T3 DK 1115725 T3 DK1115725 T3 DK 1115725T3 DK 99948776 T DK99948776 T DK 99948776T DK 99948776 T DK99948776 T DK 99948776T DK 1115725 T3 DK1115725 T3 DK 1115725T3
Authority
DK
Denmark
Prior art keywords
tetrahydropyridoethers
naphthyridine
imidazo
methoxyethoxy
tetrahydro
Prior art date
Application number
DK99948776T
Other languages
Danish (da)
English (en)
Inventor
Stefan Postius
Wolfgang-Alexander Simon
Gerhard Grundler
Guido Hanauer
Reinhard Huber
Wolfgang Kromer
Ernst Sturm
Joerg Senn-Bilfinger
Original Assignee
Altana Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag
Application granted granted Critical
Publication of DK1115725T3 publication Critical patent/DK1115725T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK99948776T 1998-09-23 1999-09-17 Tetrahydropyridoethere DK1115725T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19843504 1998-09-23
EP98117988 1998-09-23
PCT/EP1999/006899 WO2000017200A1 (en) 1998-09-23 1999-09-17 Tetrahydropyridoethers

Publications (1)

Publication Number Publication Date
DK1115725T3 true DK1115725T3 (da) 2003-06-23

Family

ID=26049024

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99948776T DK1115725T3 (da) 1998-09-23 1999-09-17 Tetrahydropyridoethere

Country Status (31)

Country Link
US (4) US6436953B1 (cs)
EP (1) EP1115725B1 (cs)
JP (1) JP4145492B2 (cs)
KR (1) KR100668400B1 (cs)
CN (2) CN1155598C (cs)
AT (1) ATE231862T1 (cs)
AU (1) AU763463B2 (cs)
BG (1) BG65195B1 (cs)
BR (1) BR9914044A (cs)
CA (1) CA2344251A1 (cs)
CZ (1) CZ292335B6 (cs)
DE (1) DE69905178T2 (cs)
DK (1) DK1115725T3 (cs)
EA (1) EA005377B1 (cs)
EE (1) EE04677B1 (cs)
ES (1) ES2191464T3 (cs)
GE (1) GEP20032926B (cs)
HK (1) HK1038360B (cs)
HR (1) HRP20010224A2 (cs)
HU (1) HUP0102990A3 (cs)
ID (1) ID28896A (cs)
IL (2) IL142063A0 (cs)
NO (1) NO317304B1 (cs)
NZ (1) NZ510610A (cs)
PL (1) PL193616B1 (cs)
PT (1) PT1115725E (cs)
RS (1) RS50145B (cs)
SI (1) SI1115725T1 (cs)
SK (1) SK285165B6 (cs)
TR (1) TR200100805T2 (cs)
WO (1) WO2000017200A1 (cs)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4145492B2 (ja) 1998-09-23 2008-09-03 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング テトラヒドロピリドエーテル
EP1173439B1 (en) 1999-04-17 2003-05-21 ALTANA Pharma AG Haloalkoxy imidazonaphthyridines
CA2721484A1 (en) * 1999-05-12 2000-11-12 President And Fellows Of Harvard College Dopamine transporter imaging agents
DE60127131T2 (de) * 2000-03-29 2007-11-22 Nycomed Gmbh Tricyclische imidazopyridine
DK1313740T3 (da) * 2000-03-29 2006-04-03 Altana Pharma Ag Prodrugs af imidazopyridinderivater
JP2004512338A (ja) * 2000-10-25 2004-04-22 アルタナ　ファルマ　アクチエンゲゼルシャフト 胃液分泌抑制剤としてのポリ置換イミダゾピリジン
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
WO2002069968A1 (en) * 2001-03-08 2002-09-12 Astrazeneca Ab New use
DE60214004T2 (de) 2001-08-02 2007-02-15 Altana Pharma Ag Tricyclische epoxide
WO2003016310A1 (en) * 2001-08-03 2003-02-27 Altana Pharma Ag Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders
EP1417208A1 (en) * 2001-08-03 2004-05-12 ALTANA Pharma AG Amino-substituted imidazopyridines for the treatment of gastrointestinal diseases
KR20040081204A (ko) 2002-02-15 2004-09-20 알타나 파마 아게 트리시클릭 ｎ-아실 화합물
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
BR0309808A (pt) * 2002-05-07 2005-03-01 Altana Pharma Ag Combinação para o tratamento de distúrbios das vias aéreas
CN100384842C (zh) 2002-11-19 2008-04-30 奥坦纳医药公司 8-取代的咪唑并吡啶类化合物
RS51707B (sr) 2002-12-12 2011-10-31 Nycomed Gmbh. Kombinacija leka sastavljena od r, r - formoterola i ciklezonida
MXPA05006349A (es) * 2002-12-20 2005-08-26 Altana Pharma Ag 8-trialquisiloxi -2-metil -9-fenil -7- oxo-7, 8, 9, 10- tetrahidroimidazo [1, 2h] [1, 7].
WO2004071391A2 (en) * 2003-02-17 2004-08-26 Altana Pharma Ag Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders
ME00524B (me) 2003-03-10 2011-10-10 Astrazeneca Ab Novi postupak za dobijanje roflumilasta
TW200503783A (en) * 2003-04-11 2005-02-01 Altana Pharma Ag Oral pharmaceutical preparation for proton pump antagonists
SA04250092B1 (ar) * 2003-05-14 2008-05-04 التانا فاروا ايه جي مركب وسيط جديد لتحضير مركبات إيميدازوبيريدين imidazopyridines فعالة علاجياً
WO2004105795A1 (en) * 2003-05-27 2004-12-09 Altana Pharma Ag Pharmaceutical combinations of a proton pump inhibitor and a compound which modifies gastrointestinal motility
BRPI0414046A (pt) * 2003-08-29 2006-10-24 Dynogen Pharmaceuticals Inc método de tratamento de um distúrbio de motilidade gastrintestinal, de tratamento de "gerd", de "gerd" noturno, composição farmacêutica, kit que compreende um composto e método para aumentar a motilidade esofágica em um paciente
JP5618452B2 (ja) 2003-09-16 2014-11-05 タケダ ゲゼルシャフト ミット ベシュレンクテル ハフツングＴａｋｅｄａ ＧｍｂＨ 呼吸器疾患の治療のためのシクレソニドの使用
CN101361738A (zh) * 2003-11-03 2009-02-11 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2-a]吡啶衍生物
US7326784B2 (en) 2003-12-19 2008-02-05 Altana Pharma Ag Intermediates for the preparation of tricyclic dihydropyrano-imidazo-pyridines derivatives
NZ549011A (en) * 2004-02-17 2009-04-30 Altana Pharma Ag Tricyclic imidazopyridines and intermediates for the synthesis thereof
ATE533765T1 (de) 2004-09-03 2011-12-15 Yuhan Corp Pyrroloä2,3-cüpyridinderivate und verfahren für deren herstellung
PL1784402T3 (pl) 2004-09-03 2011-12-30 Yuhan Corp Pochodne pirolo[3,2-c]pirydyny oraz sposoby ich wytwarzania
DK1784403T3 (da) 2004-09-03 2013-10-21 Yuhan Corp Pyrrolo[3,2-b]pyridinderivater samt fremgangsmåder til deres fremstilling
CA2601250C (en) * 2005-03-16 2014-10-28 Nycomed Gmbh Taste masked dosage form containing roflumilast
EP2080513A1 (en) * 2008-01-16 2009-07-22 Schraermeyer, Ulrich, Prof. Dr. rer. nat Tetrahydropyridoethers for treatment of AMD
KR101605063B1 (ko) 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제
WO2012027240A1 (en) * 2010-08-23 2012-03-01 Schering Corporation Fused tricyclic inhibitors of mammalian target of rapamycin
JP6001168B2 (ja) * 2012-06-15 2016-10-05 バイオ‐ファーム ソリューションズ カンパニー リミテッドＢｉｏ‐Ｐｈａｒｍ Ｓｏｌｕｔｉｏｎｓ Ｃｏ．， Ｌｔｄ． フェニルアルキルスルファメート化合物及びこれを含む筋弛緩剤組成物
WO2015052256A1 (en) 2013-10-08 2015-04-16 Katairo Gmbh Tetrahydropyridoethers for the treatment of stargardt's disease

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468400A (en) * 1982-12-20 1984-08-28 Schering Corporation Antiulcer tricyclic imidazo [1,2-a]pyridines
KR890701585A (ko) 1987-07-16 1989-12-21 헤르베르크 슈키·울리히 볼프 새로운 디아졸
SE9401197D0 (sv) * 1994-04-11 1994-04-11 Astra Ab Active compounds
EP0773945A1 (de) * 1994-07-28 1997-05-21 Byk Gulden Lomberg Chemische Fabrik GmbH Acylimidazopyridine
US6197783B1 (en) * 1997-03-24 2001-03-06 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
WO1998042707A1 (en) * 1997-03-24 1998-10-01 Byk Gulden Lomberg Chemische Fabrik Gmbh Tetrahydropyrido compounds
JP4145492B2 (ja) * 1998-09-23 2008-09-03 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング テトラヒドロピリドエーテル

Also Published As

Publication number Publication date
HUP0102990A2 (hu) 2002-01-28
PT1115725E (pt) 2003-06-30
AU6192099A (en) 2000-04-10
ATE231862T1 (de) 2003-02-15
EE04677B1 (et) 2006-08-15
HRP20010224A2 (en) 2002-04-30
BG105270A (en) 2001-11-30
EE200100172A (et) 2002-06-17
US6696460B2 (en) 2004-02-24
SI1115725T1 (en) 2003-06-30
US6436953B1 (en) 2002-08-20
EP1115725A1 (en) 2001-07-18
HK1038360B (zh) 2003-05-16
TR200100805T2 (tr) 2001-08-21
EP1115725B1 (en) 2003-01-29
AU763463B2 (en) 2003-07-24
YU21401A (sh) 2004-03-12
ID28896A (id) 2001-07-12
CN1560055A (zh) 2005-01-05
CN100506821C (zh) 2009-07-01
CZ20011082A3 (cs) 2001-09-12
PL346617A1 (en) 2002-02-25
EA200100315A1 (ru) 2001-10-22
HK1038360A1 (en) 2002-03-15
ES2191464T3 (es) 2003-09-01
EA005377B1 (ru) 2005-02-24
US20040162310A1 (en) 2004-08-19
CN1155598C (zh) 2004-06-30
US7105676B2 (en) 2006-09-12
SK3992001A3 (en) 2001-12-03
NO20011243L (no) 2001-03-12
NZ510610A (en) 2003-07-25
CZ292335B6 (cs) 2003-09-17
IL142063A (en) 2007-10-31
HUP0102990A3 (en) 2002-09-30
BG65195B1 (bg) 2007-06-29
BR9914044A (pt) 2001-12-04
NO317304B1 (no) 2004-10-04
RS50145B (sr) 2009-03-25
DE69905178D1 (de) 2003-03-06
KR20010075223A (ko) 2001-08-09
US20020169320A1 (en) 2002-11-14
IL142063A0 (en) 2002-03-10
CN1319101A (zh) 2001-10-24
WO2000017200A1 (en) 2000-03-30
SK285165B6 (sk) 2006-07-07
CA2344251A1 (en) 2000-03-30
NO20011243D0 (no) 2001-03-12
DE69905178T2 (de) 2003-07-17
JP2002526499A (ja) 2002-08-20
PL193616B1 (pl) 2007-02-28
JP4145492B2 (ja) 2008-09-03
KR100668400B1 (ko) 2007-01-17
US7393860B1 (en) 2008-07-01
GEP20032926B (en) 2003-03-25

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