DK1106608T3 - Substituerede (dihydro)benzoxazin- og (dihydro)benzothiazinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse - Google Patents

Substituerede (dihydro)benzoxazin- og (dihydro)benzothiazinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Info

Publication number: DK1106608T3
Authority: DK; Denmark
Prior art keywords: alkyl; dihydro; nrr; benzoxazine; halo
Prior art date: 1999-12-06

Application number

DK00403399T

Other languages

English (en)

Inventor

Marie-Claude Viaud

Gerald Guillaumet

Philippe Daubos

Caroline Bennejean

Philippe Delagrange

Pierre Renard

Original Assignee

Servier Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-06

Filing date

2000-12-05

Publication date

2003-06-02

2000-12-05 Application filed by Servier Lab filed Critical Servier Lab

2003-06-02 Application granted granted Critical

2003-06-02 Publication of DK1106608T3 publication Critical patent/DK1106608T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hematology (AREA)
Obesity (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Child & Adolescent Psychology (AREA)
Vascular Medicine (AREA)
Anesthesiology (AREA)
Hospice & Palliative Care (AREA)
Emergency Medicine (AREA)
Psychology (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

DK00403399T 1999-12-06 2000-12-05 Substituerede (dihydro)benzoxazin- og (dihydro)benzothiazinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse DK1106608T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9915309A FR2801885B1 (fr)	1999-12-06	1999-12-06	Nouveaux derives (dihydro)benzoxaziniques et (dihydro) benzothiaziniques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number	Publication Date
DK1106608T3 true DK1106608T3 (da)	2003-06-02

Family

ID=9552901

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK00403399T DK1106608T3 (da)	1999-12-06	2000-12-05	Substituerede (dihydro)benzoxazin- og (dihydro)benzothiazinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse

Country Status (23)

Country	Link
US (1)	US6620809B2 (da)
EP (1)	EP1106608B1 (da)
JP (1)	JP3572012B2 (da)
KR (1)	KR100491601B1 (da)
CN (1)	CN1147482C (da)
AT (1)	ATE233744T1 (da)
AU (1)	AU774186B2 (da)
BR (1)	BR0005736A (da)
CA (1)	CA2328553A1 (da)
DE (1)	DE60001534T2 (da)
DK (1)	DK1106608T3 (da)
EA (1)	EA004762B1 (da)
ES (1)	ES2193926T3 (da)
FR (1)	FR2801885B1 (da)
HK (1)	HK1038741A1 (da)
HU (1)	HUP0004837A2 (da)
MX (1)	MX223546B (da)
NO (1)	NO317991B1 (da)
NZ (1)	NZ508631A (da)
PL (1)	PL344300A1 (da)
SI (1)	SI1106608T1 (da)
TR (1)	TR200300359T4 (da)
ZA (1)	ZA200007214B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003289222A1 (en) *	2002-12-06	2004-06-30	Toray Industries, Inc.	Benzomorpholine derivatives
FR2853649B1 (fr) *	2003-04-09	2006-07-14	Servier Lab	Nouveaux derives d'isoquinoleine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US20090042874A1 (en) *	2007-05-30	2009-02-12	Wyeth	Antidepressant heteroaryl derivatives of heterocycle-fused benzodioxans

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1173942A (en) *	1967-06-06	1969-12-10	Bellon Labor Sa Roger	New 2,3-Dihydro-1,4-Benzoxazines
CA2035147A1 (en) *	1990-02-08	1991-08-09	Kousuke Yasuda	Thiazine (or oxazine) derivatives and preparation thereof
KR20010042296A (ko) *	1998-03-31	2001-05-25	로즈 암스트롱, 크리스틴 에이. 트러트웨인	세린 프로테아제 억제제로서의 벤즈옥사지논/벤조티아지논

1999
- 1999-12-06 FR FR9915309A patent/FR2801885B1/fr not_active Expired - Fee Related
2000
- 2000-12-01 NO NO20006128A patent/NO317991B1/no unknown
- 2000-12-04 MX MXPA00011967 patent/MX223546B/es active IP Right Grant
- 2000-12-05 PL PL00344300A patent/PL344300A1/xx not_active Application Discontinuation
- 2000-12-05 JP JP2000369913A patent/JP3572012B2/ja not_active Expired - Fee Related
- 2000-12-05 DE DE60001534T patent/DE60001534T2/de not_active Expired - Fee Related
- 2000-12-05 EP EP00403399A patent/EP1106608B1/fr not_active Expired - Lifetime
- 2000-12-05 DK DK00403399T patent/DK1106608T3/da active
- 2000-12-05 TR TR2003/00359T patent/TR200300359T4/xx unknown
- 2000-12-05 AT AT00403399T patent/ATE233744T1/de not_active IP Right Cessation
- 2000-12-05 NZ NZ508631A patent/NZ508631A/en unknown
- 2000-12-05 ES ES00403399T patent/ES2193926T3/es not_active Expired - Lifetime
- 2000-12-05 US US09/730,119 patent/US6620809B2/en not_active Expired - Fee Related
- 2000-12-05 EA EA200001157A patent/EA004762B1/ru not_active IP Right Cessation
- 2000-12-05 SI SI200030062T patent/SI1106608T1/xx unknown
- 2000-12-06 BR BR0005736-3A patent/BR0005736A/pt not_active IP Right Cessation
- 2000-12-06 CN CNB001372513A patent/CN1147482C/zh not_active Expired - Fee Related
- 2000-12-06 CA CA002328553A patent/CA2328553A1/fr not_active Abandoned
- 2000-12-06 KR KR10-2000-0073761A patent/KR100491601B1/ko not_active IP Right Cessation
- 2000-12-06 ZA ZA200007214A patent/ZA200007214B/xx unknown
- 2000-12-06 AU AU72073/00A patent/AU774186B2/en not_active Ceased
- 2000-12-06 HU HU0004837A patent/HUP0004837A2/hu unknown
2001
- 2001-12-27 HK HK01109066A patent/HK1038741A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
ATE233744T1 (de)	2003-03-15
TR200300359T4 (tr)	2004-02-23
US6620809B2 (en)	2003-09-16
EA004762B1 (ru)	2004-08-26
JP2001187787A (ja)	2001-07-10
ZA200007214B (en)	2001-06-06
AU7207300A (en)	2001-06-07
EP1106608A1 (fr)	2001-06-13
JP3572012B2 (ja)	2004-09-29
AU774186B2 (en)	2004-06-17
PL344300A1 (en)	2001-06-18
KR20010062170A (ko)	2001-07-07
US20010003747A1 (en)	2001-06-14
CN1147482C (zh)	2004-04-28
SI1106608T1 (en)	2003-06-30
HK1038741A1 (en)	2002-03-28
MX223546B (es)	2004-10-19
NO317991B1 (no)	2005-01-17
NZ508631A (en)	2002-03-01
CN1308069A (zh)	2001-08-15
NO20006128D0 (no)	2000-12-01
EA200001157A3 (ru)	2001-08-27
HUP0004837A2 (hu)	2002-04-29
FR2801885B1 (fr)	2002-01-11
EP1106608B1 (fr)	2003-03-05
NO20006128L (no)	2001-06-07
ES2193926T3 (es)	2003-11-16
FR2801885A1 (fr)	2001-06-08
KR100491601B1 (ko)	2005-05-27
DE60001534T2 (de)	2004-01-08
BR0005736A (pt)	2001-07-17
HU0004837D0 (da)	2001-02-28
DE60001534D1 (de)	2003-04-10
EA200001157A2 (ru)	2001-06-25
MXPA00011967A (es)	2002-05-23
CA2328553A1 (fr)	2001-06-06

Publication	Publication Date	Title
ATE206412T1 (de)	2001-10-15	Heterocyclische verbindungen als bradykinin antagonisten
DK1389617T3 (da)	2007-05-07	Heterocyclisk forbindelse og antitumormiddel indeholdende denne som den aktive bestanddel
NO995175D0 (no)	1999-10-22	Nye dihydro- og tetrahydrokinolinforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem
MX9202142A (es)	1993-06-01	Nuevos derivados de urea, proceso para su preparacion, y composicion farmaceutica que los comprende.
IL144461A0 (en)	2002-05-23	Quinoline and quinazoline derivatives and pharmaceutical compositions containing them
AU3113793A (en)	1993-03-11	Intermediates for preparing antipicornaviral pyridazinamines
DK1106608T3 (da)	2003-06-02	Substituerede (dihydro)benzoxazin- og (dihydro)benzothiazinderivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
CA2254755A1 (en)	1997-11-27	Hexahydro-pyrido(4,3-b)indole derivatives as antipsychotic drugs
AR016501A1 (es)	2001-07-04	Compuestos inhibidores de las fkbp, composiciones farmaceuticas, uso para la preparacion de medicamentos y procesos de preparacion e intermediarios.
DK1061081T3 (da)	2002-08-12	Nye afledede af 7-oxo-2,3,7,14-tetrahydro-1H-benzo[b]pyrano[3,2-h]acridinecarboxylat, fremgangsmåder til fremstilling heraf og farmaceutiske tilberedninger, som indeholder disse
IL116386A (en)	1999-06-20	Preparation of pharmaceutical compositions containing 1,2-bridged 1,4-dihydropyridines for the control of cns disorders and sickle cell anemia certain such novel compounds and their preparation
EA200400667A2 (ru)	2004-12-30	Новые соединения бензотиазина и бензотиадиазина, способ их получения и фармацевтические композиции, которые их содержат
GR3034748T3 (en)	2001-02-28	Bis imide derivatives, process for their preparation and pharmaceutical compositions containing them
PT1010694E (pt)	2003-10-31	Derivados espiroimidazolinicos e a sua utilizacao como antagonistas alfa2-adrenergicos e bloqueadores da recaptura de monoaminas
EA200200379A2 (ru)	2002-10-31	Новые соединения пиримидин-4-она, способ их получения и содержащие их фармацевтические композиции
HU9801822D0 (en)	1998-10-28	New bis-pyrido4,3-bòcarbozole compounds, a process for their preparation and pharmaceutical compositions containing them