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DK0983249T3 - Fremgangsmåder og mellemprodukter til fremstilling af substituerede indazolderivater - Google Patents

Fremgangsmåder og mellemprodukter til fremstilling af substituerede indazolderivater

Info

Publication number
DK0983249T3
DK0983249T3 DK98913997T DK98913997T DK0983249T3 DK 0983249 T3 DK0983249 T3 DK 0983249T3 DK 98913997 T DK98913997 T DK 98913997T DK 98913997 T DK98913997 T DK 98913997T DK 0983249 T3 DK0983249 T3 DK 0983249T3
Authority
DK
Denmark
Prior art keywords
intermediates
preparation
methods
indazole derivatives
substituted indazole
Prior art date
Application number
DK98913997T
Other languages
English (en)
Inventor
Stephane Caron
Shane Allen Eisenbeis
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of DK0983249T3 publication Critical patent/DK0983249T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DK98913997T 1997-05-08 1998-04-28 Fremgangsmåder og mellemprodukter til fremstilling af substituerede indazolderivater DK0983249T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4685897P 1997-05-08 1997-05-08
PCT/IB1998/000647 WO1998050367A1 (en) 1997-05-08 1998-04-28 Processes and intermediates for preparing substituted indazole derivatives

Publications (1)

Publication Number Publication Date
DK0983249T3 true DK0983249T3 (da) 2002-07-08

Family

ID=21945777

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98913997T DK0983249T3 (da) 1997-05-08 1998-04-28 Fremgangsmåder og mellemprodukter til fremstilling af substituerede indazolderivater

Country Status (12)

Country Link
US (1) US6011159A (da)
EP (1) EP0983249B1 (da)
JP (1) JP3399546B2 (da)
AR (2) AR015648A1 (da)
AT (1) ATE214373T1 (da)
AU (1) AU6849798A (da)
DE (1) DE69804212T2 (da)
DK (1) DK0983249T3 (da)
ES (1) ES2172882T3 (da)
PT (1) PT983249E (da)
WO (1) WO1998050367A1 (da)
ZA (1) ZA983842B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2001002304A0 (en) * 1996-05-03 2001-12-31 Pfizer Substituted indazole derivatives and related compounds
CA2309175A1 (en) * 1997-11-04 1999-05-14 Pfizer Products Inc. Therapeutically active compounds based on indazole bioisostere replacement of catechol in pde4 inhibitors
JP2000198734A (ja) * 1998-12-30 2000-07-18 Pfizer Inc 胃運動性減弱および関連疾患の治療のための運動性増強薬
KR100423899B1 (ko) * 2000-05-10 2004-03-24 주식회사 엘지생명과학 세포 증식 억제제로 유용한 1,1-디옥소이소티아졸리딘을갖는 인다졸
DE102004005172A1 (de) * 2004-02-02 2005-08-18 Aventis Pharma Deutschland Gmbh Indazolderivate als Inhibitoren der Hormon Sensitiven Lipase
UA88792C2 (ru) * 2004-11-10 2009-11-25 Таргасепт, Інк. Гидроксибензоатные соли метаникотиновых соединений
US7459469B2 (en) 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
TWI389889B (zh) 2006-05-09 2013-03-21 Targacept Inc (2s)-(4e)-n-甲基-5-〔3-(5-異丙氧基吡啶)基〕-4-戊烯-2-胺之新穎多晶型
EP2021325A2 (en) 2006-05-09 2009-02-11 AstraZeneca AB Salt forms of (2s)-(4e)-n-methyl-5-[3-(5-isopropoxypyridin)yl]-4-penten-2-amine

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1050129C (zh) * 1994-10-20 2000-03-08 美国辉瑞有限公司 二环四氢吡唑并吡啶和其作为药物的应用
AP2001002304A0 (en) * 1996-05-03 2001-12-31 Pfizer Substituted indazole derivatives and related compounds

Also Published As

Publication number Publication date
EP0983249B1 (en) 2002-03-13
DE69804212D1 (de) 2002-04-18
JP3399546B2 (ja) 2003-04-21
US6011159A (en) 2000-01-04
AR016737A1 (es) 2001-07-25
ZA983842B (en) 1999-11-08
ES2172882T3 (es) 2002-10-01
AU6849798A (en) 1998-11-27
DE69804212T2 (de) 2002-07-25
EP0983249A1 (en) 2000-03-08
PT983249E (pt) 2002-08-30
ATE214373T1 (de) 2002-03-15
JP2000513019A (ja) 2000-10-03
WO1998050367A1 (en) 1998-11-12
AR015648A1 (es) 2001-05-16

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