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DK0877801T3 - Morfologiske mutanter af trådsvampe - Google Patents

Morfologiske mutanter af trådsvampe

Info

Publication number
DK0877801T3
DK0877801T3 DK97904806T DK97904806T DK0877801T3 DK 0877801 T3 DK0877801 T3 DK 0877801T3 DK 97904806 T DK97904806 T DK 97904806T DK 97904806 T DK97904806 T DK 97904806T DK 0877801 T3 DK0877801 T3 DK 0877801T3
Authority
DK
Denmark
Prior art keywords
cell
mutant
parent
filamentous fungi
identifying
Prior art date
Application number
DK97904806T
Other languages
English (en)
Inventor
Jeffrey R Shuster
John C Royer
Original Assignee
Novozymes Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes Biotech Inc filed Critical Novozymes Biotech Inc
Application granted granted Critical
Publication of DK0877801T3 publication Critical patent/DK0877801T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
    • C12N9/2437—Cellulases (3.2.1.4; 3.2.1.74; 3.2.1.91; 3.2.1.150)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/66—Aspergillus
    • C12R2001/69—Aspergillus oryzae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/77—Fusarium

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK97904806T 1996-01-19 1997-01-17 Morfologiske mutanter af trådsvampe DK0877801T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1023896P 1996-01-19 1996-01-19
US72611496A 1996-10-04 1996-10-04
PCT/US1997/000829 WO1997026330A2 (en) 1996-01-19 1997-01-17 Morphological mutants of filamentous fungi

Publications (1)

Publication Number Publication Date
DK0877801T3 true DK0877801T3 (da) 2005-08-29

Family

ID=26680948

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97904806T DK0877801T3 (da) 1996-01-19 1997-01-17 Morfologiske mutanter af trådsvampe

Country Status (9)

Country Link
US (5) US6066493A (da)
EP (3) EP1605050A3 (da)
JP (1) JP3792725B2 (da)
CN (1) CN1231588C (da)
AT (1) ATE294233T1 (da)
AU (1) AU1750697A (da)
DE (1) DE69733121T2 (da)
DK (1) DK0877801T3 (da)
WO (1) WO1997026330A2 (da)

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CN100392077C (zh) 1997-12-22 2008-06-04 诺维信公司 糖氧化酶及其在焙烤中的用途
BRPI9914278B1 (pt) * 1998-10-06 2016-03-08 Dyadic Internat Usa Inc cepa recombinante de chrysosporium, e, método para produzir um polipeptídeo de interesse
EP2278016B1 (en) 1999-03-22 2012-09-26 Novozymes Inc. Promoter sequences derived from Fusarium Venenatum and uses thereof
US6361973B1 (en) 1999-03-22 2002-03-26 Novozymes Biotech, Inc. Promoters for expressing genes in a fungal cell
US6995239B1 (en) * 1999-03-24 2006-02-07 Genencor International, Inc. Hyphal growth in fungi
US7189538B2 (en) * 1999-03-24 2007-03-13 Genencor International, Inc. Hyphal growth in fungi
US7122330B2 (en) 2000-04-13 2006-10-17 Mark Aaron Emalfarb High-throughput screening of expressed DNA libraries in filamentous fungi
CA2376552A1 (en) * 2000-04-13 2001-10-25 Emalfarb, Mark Aaron High-throughput screening of expressed dna libraries in filamentous fungi
EP2281878A1 (en) 2000-06-26 2011-02-09 Novozymes A/S Lipolytic enzyme
US6558715B1 (en) * 2000-10-31 2003-05-06 Novozymes Biotech, Inc. Methods for using lipases in baking
US6824798B2 (en) * 2001-09-27 2004-11-30 J. Gregory Koenig Method of preventing veisalgia
US20040018573A1 (en) * 2002-04-18 2004-01-29 Power Scott D Production of functional antibodies in filamentous fungi
AU2003231228A1 (en) 2002-04-22 2003-11-03 Novozymes Biotech, Inc. Methods for preparing variants of a dna sequence in filamentous fungi
WO2003089617A2 (en) 2002-04-22 2003-10-30 Novozymes Biotech, Inc. Methods for increasing homologous recombination of a nucleic acid sequence
DK1546302T3 (da) 2002-08-30 2009-12-14 Novozymes Inc Fremgangsmåder til fremstilling af pattedyrs-trypsiner
DK1585822T3 (da) 2002-11-18 2012-05-14 Novozymes Inc Promotorvarianter til ekspression af gener i en fungal celle
CA2511656A1 (en) * 2002-12-24 2004-07-15 Ikeda Food Research Co., Ltd. Coenzyme-binding glucose dehydrogenase
WO2004099228A2 (en) 2003-05-02 2004-11-18 Novozymes Inc. Variants of beta-glucosidases
EP2377931B1 (en) 2003-08-25 2013-05-08 Novozymes Inc. Variants of glycoside hydrolases
JP4809347B2 (ja) 2004-06-14 2011-11-09 ノボザイムス アクティーゼルスカブ ポリペプチド製造用シグナルペプチド
US20060080393A1 (en) * 2004-10-12 2006-04-13 Cardone Richard J Method for using e-mail documents to create and update address lists
CA2600693A1 (en) * 2005-03-24 2006-09-28 Dsm Ip Assets B.V. Process for microbial production of a valuable compound
JP5020070B2 (ja) 2005-03-25 2012-09-05 池田食研株式会社 補酵素結合型グルコース脱水素酵素をコードするポリヌクレオチド
US9862956B2 (en) 2006-12-10 2018-01-09 Danisco Us Inc. Expression and high-throughput screening of complex expressed DNA libraries in filamentous fungi
WO2008073914A2 (en) 2006-12-10 2008-06-19 Dyadic International Inc. Expression and high-throughput screening of complex expressed dna libraries in filamentous fungi
EP2121916A1 (en) * 2006-12-20 2009-11-25 Danisco US, INC., Genencor Division Assays for improved fungal strains
US20100221783A1 (en) 2007-05-09 2010-09-02 Novozymes A/S Expression Cloning Method Suitable for Selecting Library Clones Producing a Polypeptide of Interest
US8551751B2 (en) 2007-09-07 2013-10-08 Dyadic International, Inc. BX11 enzymes having xylosidase activity
MX350399B (es) 2009-12-18 2017-09-06 Novozymes Inc Metodos para producir polipeptidos en mutantes de trichoderma deficientes en proteasa.
CN103003439A (zh) * 2010-06-22 2013-03-27 中化帝斯曼制药有限公司荷兰公司 气泡发酵工艺
CA2846391A1 (en) 2011-08-24 2013-02-28 Novozymes, Inc. Aspergillus fumigatus cellulolytic enzyme compositions and uses thereof
CN103890180A (zh) 2011-08-24 2014-06-25 诺维信股份有限公司 在丝状真菌宿主细胞中产生多种重组多肽的方法
CA2846398A1 (en) 2011-08-24 2013-02-28 Novozymes, Inc. Cellulolytic enzyme compositions and uses thereof
WO2013028915A2 (en) 2011-08-24 2013-02-28 Novozymes, Inc. Methods for obtaining positive transformants of a filamentous fungal host cell
WO2013102674A2 (en) 2012-01-05 2013-07-11 Novartis International Pharmaceutical Ltd. Protease deficient filamentous fungal cells and methods of use thereof
WO2013174927A1 (en) 2012-05-23 2013-11-28 Novartis International Pharmaceutical Limited Production of fucosylated glycoproteins
CN104603269A (zh) 2012-08-17 2015-05-06 诺维信公司 用于在丝状真菌菌株中共沉默基因表达的方法及其应用
US10023872B2 (en) 2012-12-21 2018-07-17 Novozymes, Inc. Methods for producing heterologous polypeptides in mutants of trichoderma
RU2016104064A (ru) 2013-07-10 2017-08-15 Новартис Аг Клетки мицелиальных грибов с множественной недостаточностью протеаз и способы их использования
US20170166939A1 (en) 2013-11-26 2017-06-15 Novozymes A/S Enzyme Compositions and Uses Thereof
CN106488982A (zh) 2014-06-06 2017-03-08 诺维信公司 酶组合物及其用途
US10513724B2 (en) 2014-07-21 2019-12-24 Glykos Finland Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
WO2020123845A1 (en) 2018-12-12 2020-06-18 Novozymes A/S Methods for increasing the productivity of a filamentous fungal cell in the production of a polypeptide
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Also Published As

Publication number Publication date
EP1605050A2 (en) 2005-12-14
JP2000503537A (ja) 2000-03-28
WO1997026330A3 (en) 1997-10-09
US6066493A (en) 2000-05-23
WO1997026330A2 (en) 1997-07-24
US7198938B2 (en) 2007-04-03
EP1605050A3 (en) 2006-03-22
EP0877801A2 (en) 1998-11-18
EP0877801B1 (en) 2005-04-27
EP2295581A2 (en) 2011-03-16
US6794180B2 (en) 2004-09-21
US6544774B1 (en) 2003-04-08
AU1750697A (en) 1997-08-11
DE69733121D1 (de) 2005-06-02
US20040266009A1 (en) 2004-12-30
JP3792725B2 (ja) 2006-07-05
CN1231588C (zh) 2005-12-14
EP2295581A3 (en) 2011-05-04
US6184026B1 (en) 2001-02-06
ATE294233T1 (de) 2005-05-15
US20040009579A1 (en) 2004-01-15
CN1219971A (zh) 1999-06-16
DE69733121T2 (de) 2006-03-02

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